Aliases for PADI6 Gene
External Ids for PADI6 Gene
Previous GeneCards Identifiers for PADI6 Gene
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. This protein may play a role in cytoskeletal reorganization in the egg and in early embryo development. [provided by RefSeq, Sep 2012]
GeneCards Summary for PADI6 Gene
PADI6 (Peptidyl Arginine Deiminase 6) is a Protein Coding gene. Diseases associated with PADI6 include Preimplantation Embryonic Lethality 2 and Preimplantation Embryonic Lethality. Among its related pathways are Chromatin organization and protein citrullination. GO annotations related to this gene include calcium ion binding and protein-arginine deiminase activity. An important paralog of this gene is PADI4.
UniProtKB/Swiss-Prot for PADI6 Gene
Catalyzes the deimination of arginine residues of proteins (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo (PubMed:27545678).