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PACS2 Gene

protein-coding GIFtS: 50

GC14P104839

phosphofurin acidic cluster sorting protein 2
(Previous name: phosphofurin acidic cluster sorting protein 1-like )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: PACS1L)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ25488 ^²
KIAA0602 ^¹, ², ³
PACS-2 ^³
PACS1L ^², ³

Descriptions
PACS1-like protein ^³
phosphofurin acidic cluster sorting protein 1-like ^¹, ²
phosphofurin acidic cluster sorting protein 2 ^²

External Ids
HGNC: 23794¹
Entrez Gene: 23241²
UniProtKB: Q86VP3³
Ensembl: ENSG00000179364⁷

Search outside databases for aliases for PACS2 gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: PACS2_HUMAN, Q86VP3

Function: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria

communication, including the apposition of mitochondria with the ER and ER homeostasis. In

addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a

sequence of events including the formation of mitochondrial truncated BID, the release of

cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion

channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular

compartments

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the PACS2 gene

Entrez Gene cytogenetic band: 14q32.33 Ensembl cytogenetic band: 14q32.33 HGNC cytogenetic band: 14q32

PACS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 14 GeneLoc Exon Structure

GeneLoc location for GC14P104839: (about GC identifiers)

Start:	104,852,126 bp from pter
End:	104,935,529 bp from pter
Size:	83,404 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000014.7 NT_026437.11

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: PACS2_HUMAN, Q86VP3 (See protein sequence)

Recommended Name: Phosphofurin acidic cluster sorting protein 2

Size: 889 amino acids; 97702 Da

Subunit: Interacts with BID and PKD2

Subcellular location: Endoplasmic reticulum lumen. Mitochondrion

Secondary accessions: A2VDJ9 O60342 Q6P191 Q96FL7

Alternative splicing: 3 isoforms: Q86VP3-1 Q86VP3-2 Q86VP3-3

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (2 alternative transcripts):

NP_001094383.1 NP_056012.2

ENSEMBL proteins:

ENSP00000321834

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse Abcam for Recombinant Proteins
	Human Recombinant Proteins from Abnova (PACS2)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IEA	--
GO:0005783	endoplasmic reticulum	IEA	--
GO:0005788	endoplasmic reticulum lumen	IEA	--

About this table

Antibodies for PACS2:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for PACS2
	Browse R&D Systems for Antibodies
	Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for PACS2

Assays for PACS2:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q86VP3

ProtoNet protein and cluster: Q86VP3

UniProtKB/Swiss-Prot: PACS2_HUMAN, Q86VP3

Similarity: Belongs to the PACS family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (PACS2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): XM_290619

Applied Biosystems Silencer® siRNAs for PACS2

Sigma-Aldrich siRNA for PACS2

Sigma-Aldrich shRNA for PACS2

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for PACS2
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001100913
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001100913
untagged cDNA clones in CMV expression vector (see all 3): BC028418

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001100913

UniProtKB/Swiss-Prot: PACS2_HUMAN, Q86VP3

Function: Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria

communication, including the apposition of mitochondria with the ER and ER homeostasis. In

addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a

sequence of events including the formation of mitochondrial truncated BID, the release of

cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion

channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular

compartments

1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Pacs2):

no phenotypic analysis

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/7 Interacting proteins for PACS2 (ENSP00000321834³) via UniProtKB, MINT, and/or STRING (see all 7 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PKD2	ENSP00000237596³	STRING (score=.944)
CANX	ENSP00000247461³	STRING (score=.876)
BCAP31	ENSP00000343458³	STRING (score=.822)
CRAMP1L	ENSP00000293925³	STRING (score=.748)
DBT	ENSP00000359151³	STRING (score=.748)

About this table

1 Gene Ontology (GO) biological process term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006915	apoptosis	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for PACS2

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (PACS2)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): XM_290619

Sigma-Aldrich siRNA for PACS2

Sigma-Aldrich shRNA for PACS2

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001100913 NM_015197

REFSEQ mRNAs for PACS2 gene (2 alternative transcripts):

NM_001100913.1 NM_015197.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001100913 NM_015197

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_001100913
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_001100913
                                 untagged cDNA clones in CMV expression vector (see all 3): BC028418

Additional cDNA sequence:

AB011174.1 AB072449.1 AK098354.1 AY320284.2 BC010663.1 BC028418.1 BC050351.1 BC065220.1

BC095493.1 BC131591.1 CR609884.1 CR619350.1

17 DOTS entries:

DT.95340845 DT.75136750 DT.100784499 DT.100784498 DT.99931200 DT.104677 DT.91725829 DT.100028808

DT.75113716 DT.100737432 DT.100784500 DT.120730234 DT.40253424 DT.40314722 DT.91723664 DT.95173287

DT.91723668

24/183 AceView cDNA sequences (see all 183 ):

BI910927 BQ681025 BU541359 BQ877534 CA388842 BG165261 BQ100979 BM974520

CA488597 AW516912 CO246386 AI361320 AL079470 BQ669918 BM558228 BC010663

BM709620 Z45646 AB011174 BG392373 AI419333 AL044754 BM973747 BQ086326

highest scoring ESTs for PACS2:

AB011174 AA156660 AA159210 AA193428 AA193451 AA367168 AA454581 AA456475 AA558972 AA661639

Unigene Cluster for PACS2:

Phosphofurin acidic cluster sorting protein 2

Hs.525626 [show with all ESTs]

Unigene Representative Sequence: NM_001100913

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for PACS2 (see all 10 )

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5	^	6a	·	6b	^	7	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13	^	14a	·	14b	^	15	^	16	^	17a	·	17b	^	18	^	19	^	20	^	21a	·
SP1:			-				-																-																												-
SP2:			-				-																-												-														-		-
SP3:
SP4:							-
SP5:

ExUns:	21b	·	21c	·	21d	^	22	^	23a	·	23b	·	23c	^	24	^	25a	·	25b	^	26	^	27a	·	27b	·	27c	·	27d
SP1:	-								-		-		-
SP2:	-								-		-		-
SP3:									-		-		-
SP4:
SP5:

About this scheme

ECgene alternative splicing isoforms for PACS2

1 Ensembl transcript including schematic representation:

ENST00000325438

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

PACS2 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for PACS2

¹ / ² / ³

7 probe-sets matching PACS2 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34406_at²^{, 3}	U133-A	1	1.00	1.00	1.00	1.00	AB011174	1.00	1.00	1.00	1
34406_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AB011174	1.00	1.00	1.00	1
212778_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AL583340	0.60	1.00	0.82	1
1555823_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
34406_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
212778_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1555824_a_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGGCCGCTCA

SOURCE GeneReport for Unigene cluster: Hs.525626
Expression variation in blood from EXPOLDB for PACS2
UniProtKB/Swiss-Prot: PACS2_HUMAN, Q86VP3
Tissue specificity: Broadly expressed, with greatest levels in skeletal muscle followed by heart,
brain, pancreas and testis

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for PACS2 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	PACS2¹	--	phosphofurin acidic cluster sorting protein 2	89.02(n) 93.07(a)	490884 XM_548006.2 XP_548006.2
mouse (Mus musculus)	Pacs2^{1, 5}	12⁵	phosphofurin acidic cluster sorting protein 2^{1, 5}	88.08(n)¹ 94.6(a)¹	217893¹ NM_001081170.1¹ NP_001074639.1¹ AI607305⁵ AI847353⁵ (see all 19)
chicken (Gallus gallus)	PACS2¹	--	phosphofurin acidic cluster sorting protein 2	78.6(n) 86.15(a)	424375 XM_422219.2 XP_422219.2
zebrafish (Danio rerio)	si:ch211-126j24.1¹	--	si:ch211-126j24.1	67.06(n) 63.92(a)	571137 XM_694701.3 XP_699793.3
fruit fly (Drosophila melanogaster)	KrT95D¹	--	Krueppel target at 95D	49.07(n) 39.65(a)	42843 NM_170110.2 NP_732935.2

About this table Species with no ortholog for PACS2

ENSEMBL Gene Tree for PACS2

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for PACS2 gene

PACS1²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/286 NCBI SNPs in PACS2 are shown (see all 286 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 78)

AB	SNP ID	Valid	Chr 14 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs11847153^1,2	A,C,F,H	104850210(+)	`GTGACA/GCATGG`	2	--	ng5¹ tfbs³		4	EU EA WA	418
	rs8010888^1,2	A,C,F,H	104904724(+)	`ACAGCA/GCCATG`	2	T/A	mis¹		4	EU EA WA	412
	rs11847295^1,2	C,F,H	104850350(+)	`AGGCCG/ACCATC`	2	--	ng5¹		4	EU EA WA	418
	rs10141888^1,2	A,F,H	104933618(+)	`TCCCAG/ACCAGA`	2	--	ut3¹		4	EU EA WA	416
	rs12880235^1,2	H	104933742(+)	`CCCGAG/AAAGTG`	2	--	ut3¹		4	EU EA WA	418
	rs4074004^1,2	A,C,F,H	104914224(-)	`TCCAGG/CGTGTC`	2	T/T	syn¹ ese³		7	EU EA WA NA	548
	rs4076933^1,2	A,C,F,H	104919936(+)	`ATCCTT/CGTCAA`	2	L/L	syn¹ ese³		8	EU EA WA	836
	rs4074003^1,2	F,H	104914245(-)	`CTGTCG/ACTGGG`	2	S/S	syn¹ ese³		4	EU EA WA	418
	rs10148890^1,2	A,C,F,H	104876100(+)	`GGGTGC/TCCAGG`	2	--	int¹		4	EU EA WA	418
	rs7494470^1,2	A,C,F,H	104918893(+)	`GGCACC/GCAGGT`	2	--	int¹		4	EU EA WA	418

About this table

HapMap Linkage Disequilibrium images for PACS2 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 610423

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10 PubMed articles for PACS2 gene:

PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis. (PubMed id 15692567)^{2, 3, 4} Simmen T.... Thomas G. (2005)
Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation. (PubMed id 15692563)^{3, 4} Koettgen M.... Walz G. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Large-scale characterization of HeLa cell nuclear phosphoproteins. (PubMed id 15302935)^{3, 4} Beausoleil S.A....Gygi S.P. (2004)
Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9628581)^{3, 4} Nagase T....Ohara O. (1998)
HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice. (PubMed id 18296443)³ Atkins K.M....Thomas G. (2008)
The Subcellular Distribution of Calnexin Is Mediated by PACS-2. (PubMed id 18417615)³ Myhill N....Simmen T. (2008)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)³ Kimura K.... Sugano S. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)³ Strausberg R.L....Marra M.A. (2002)
Kaposi sarcoma herpesvirus K5 removes CD31/PECAM from endothelial cells. (PubMed id 16601245)¹ Mansouri M....Fruh K. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 23241	HGNC: 23794	AceView: KIAA0602	Ensembl:ENSG00000179364	euGenes: HUgn23241
ECgene: PACS2	H-InvDB: PACS2

(According to HUGE)
About This Section

HUGE: KIAA0602

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for PACS2
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for PACS2:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for PACS2-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for PACS2		Antibodies for PACS2
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for PACS2		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (PACS2)
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	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

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Search Tocris compounds for PACS2

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Search Novus for antibodies for PACS2

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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PACS2 Gene at Home site.
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PACS2 Gene

protein-coding GIFtS: 50

Aliases &
Descriptions
for PACS2

Summaries
for PACS2

Genomic Location
for PACS2

Proteins
for PACS2

Protein Domains/
Families
for PACS2

Gene Function
for PACS2

Pathways & Interactions
for PACS2

Drugs & Compounds
for PACS2

Transcripts
for PACS2

Expression
for PACS2

Orthologs
for PACS2

Paralogs
for PACS2

SNPs/Variants
for PACS2

Disorders & Mutations
for PACS2

Medical News
for PACS2

Publications
for PACS2

Search for PACS2

Genome Databases showing PACS2

Other Databases showing PACS2

Specialized Databases showing PACS2

Licensable Technologies
for PACS2

Services
for PACS2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

PACS2 Gene

protein-coding GIFtS: 50

Aliases & Descriptionsfor PACS2

Summariesfor PACS2

Genomic Locationfor PACS2

Proteinsfor PACS2

Protein Domains/Familiesfor PACS2

Gene Functionfor PACS2

Pathways & Interactionsfor PACS2

Drugs & Compoundsfor PACS2

Transcriptsfor PACS2

Expression for PACS2

Orthologsfor PACS2

Paralogsfor PACS2

SNPs/Variantsfor PACS2

Disorders & Mutationsfor PACS2

Medical Newsfor PACS2

Publicationsfor PACS2

Search for PACS2

Genome Databases showing PACS2

Other Databases showing PACS2

Specialized Databases showing PACS2

Licensable Technologiesfor PACS2

Servicesfor PACS2

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for PACS2

Summaries
for PACS2

Genomic Location
for PACS2

Proteins
for PACS2

Protein Domains/
Families
for PACS2

Gene Function
for PACS2

Pathways & Interactions
for PACS2

Drugs & Compounds
for PACS2

Transcripts
for PACS2

Expression
for PACS2

Orthologs
for PACS2

Paralogs
for PACS2

SNPs/Variants
for PACS2

Disorders & Mutations
for PACS2

Medical News
for PACS2

Publications
for PACS2

Licensable Technologies
for PACS2

Services
for PACS2