Aliases for PABPC5 Gene
External Ids for PABPC5 Gene
Previous GeneCards Identifiers for PABPC5 Gene
This gene encodes a protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010]
GeneCards Summary for PABPC5 Gene
PABPC5 (Poly(A) Binding Protein Cytoplasmic 5) is a Protein Coding gene. Diseases associated with PABPC5 include Ovarian Cystadenocarcinoma. Among its related pathways are mRNA surveillance pathway and Deadenylation-dependent mRNA decay. GO annotations related to this gene include nucleic acid binding and nucleotide binding. An important paralog of this gene is PABPC4.
UniProtKB/Swiss-Prot for PABPC5 Gene
Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).