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PABPC3 Gene

protein-coding   GIFtS: 55
GCID: GC13P025670

Poly(A) Binding Protein, Cytoplasmic 3

(Previous names: poly(A)-binding protein, cytoplasmic 3)
(Previous symbol: PABPL3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Poly(A) Binding Protein, Cytoplasmic 31 2     Poly(A)-Binding Protein-Like 32
PABPL31 2 3 5     Polyadenylate-Binding Protein 32
PABP32 3 5     tPABP2
Testis PABP1 2     Testis-Specific Poly(A)-Binding Protein (PABP)2
Poly(A)-Binding Protein 32 3     Testis-Specific Poly(A)-Binding Protein 32
PABP-32 3     Testis-Specific Poly(A)-Binding Protein3
Poly(A)-Binding Protein, Cytoplasmic 31     

External Ids:    HGNC: 85561   Entrez Gene: 50422   Ensembl: ENSG000001518467   OMIM: 6046805   UniProtKB: Q9H3613   

Export aliases for PABPC3 gene to outside databases

Previous GC identifers: GC13P023650 GC13P019650 GC13P024600 GC13P023468 GC13P024568 GC13P006483


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PABPC3 Gene:
Messenger RNA stability and translation initiation are extensively under the control of poly(A)-binding proteins
(PABP). See PABPC1 (MIM 604679) for background information.(supplied by OMIM, Jul 2002)

GeneCards Summary for PABPC3 Gene:
PABPC3 (poly(A) binding protein, cytoplasmic 3) is a protein-coding gene. Diseases associated with PABPC3 include tonsillitis, and hiv-1. GO annotations related to this gene include poly(A) binding and nucleotide binding. An important paralog of this gene is PABPC1L.

UniProtKB/Swiss-Prot: PABP3_HUMAN, Q9H361
Function: Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism.
Binds poly(A) with a slightly lower affinity as compared to PABPC1

Gene Wiki entry for PABPC3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000013.11  NC_018924.2  NT_024524.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the PABPC3 gene promoter:
         TBP   Elk-1   p53   CUTL1   AP-4   POU3F2   GATA-2   E47   AREB6   ARP-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPABPC3 promoter sequence
   Search Chromatin IP Primers for PABPC3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PABPC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q12-q13   Ensembl cytogenetic band:  13q12.13   HGNC cytogenetic band: 13q12-q13

PABPC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PABPC3 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P025670:  view genomic region     (about GC identifiers)

Start:
25,670,276 bp from pter      End:
25,673,389 bp from pter
Size:
3,114 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PABP3_HUMAN, Q9H361 (See protein sequence)
Recommended Name: Polyadenylate-binding protein 3  
Size: 631 amino acids; 70031 Da
2 PDB 3D structures from and Proteopedia for PABPC3:
2D9P (3D)        4IVE (3D)    
Secondary accessions: Q8NHV0 Q9H086

Explore the universe of human proteins at neXtProt for PABPC3: NX_Q9H361

Explore proteomics data for PABPC3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys78, Lys208, Lys213, Lys231, Lys259, Lys284, Lys333, Lys348, Lys361
  • Modification sites at PhosphoSitePlus

  • See PABPC3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_112241.2  
    ENSEMBL proteins: 
     ENSP00000281589  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    RBM: RNA binding motif (RRM) containing

    4 InterPro protein domains:
     IPR002004 PABP_HYD
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom
     IPR006515 PABP_1234

    Graphical View of Domain Structure for InterPro Entry Q9H361

    ProtoNet protein and cluster: Q9H361

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB002004 Polyadenylate-binding protein/HECT-associated


    UniProtKB/Swiss-Prot: PABP3_HUMAN, Q9H361
    Similarity: Belongs to the polyadenylate-binding protein type-1 family
    Similarity: Contains 1 PABC domain
    Similarity: Contains 4 RRM (RNA recognition motif) domains


    PABPC3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PABP3_HUMAN, Q9H361
    Function: Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism.
    Binds poly(A) with a slightly lower affinity as compared to PABPC1

         Genatlas biochemistry entry for PABPC3:
    poly(A) binding protein,cytoplasmic 3

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding ----
    GO:0008143poly(A) binding IDA11328870
         
    PABPC3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PABPC3
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    miRNA
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    miRTarBase miRNAs that target PABPC3:
    hsa-mir-149-5p (MIRT045517), hsa-mir-10a-5p (MIRT047748)

    Block miRNA regulation of human, mouse, rat PABPC3 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate PABPC3:
    hsa-miR-9* hsa-miR-186 hsa-miR-3133 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidPABPC3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PABPC3

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PABPC3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PABP3_HUMAN, Q9H361: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm NAS11328870

    PABPC3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PABPC3 About    
    See pathways by source

    SuperPathContained pathways About
    1Deadenylation-dependent mRNA decay
    RNA degradation0.48
    2RNA transport
    RNA transport
    3mRNA surveillance pathway
    mRNA surveillance pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    3 Kegg Pathways  (Kegg details for PABPC3):
        RNA transport
    mRNA surveillance pathway
    RNA degradation


    PABPC3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PABPC3
    Interactions:

        Search GeneGlobe Interaction Network for PABPC3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PABPC3 (Q9H3612, 3 ENSP000002815894) via UniProtKB, MINT, STRING, and/or I2D (see all 208)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    MOV10Q9HCE12, ENSP000003500284MINT-6488791 STRING: ENSP00000350028
    UBCP0CG482, ENSP000003448184MINT-6488791 STRING: ENSP00000344818
    EEF1A1P681042, ENSP000003300544MINT-6488791 STRING: ENSP00000330054
    AGO1Q9UL182, ENSP000003623004MINT-6488791 STRING: ENSP00000362300
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016071mRNA metabolic process NAS11328870

    PABPC3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PABPC3 (PABP3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PABPC3 gene: 
    NM_030979.2  

    Unigene Cluster for PABPC3:

    Poly(A) binding protein, cytoplasmic 3
    Hs.458280  [show with all ESTs]
    Unigene Representative Sequence: BC045608
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000281589
    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate PABPC3:
    hsa-miR-9* hsa-miR-186 hsa-miR-3133 hsa-miR-3647-3p
    SwitchGear 3'UTR luciferase reporter plasmidPABPC3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PABPC3
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    Primer
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    OriGene qPCR primer pairs and template standards for PABPC3
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    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PABPC3
      QuantiTect SYBR Green Assays in human, mouse, rat PABPC3
      QuantiFast Probe-based Assays in human, mouse, rat PABPC3

    Additional mRNA sequence: 

    AF132026.1 AK313336.1 AL136900.1 BC027617.2 BC045608.1 

    Selected DOTS entries (see all 31):

    DT.91661782  DT.95267608  DT.100700595  DT.92470838  DT.91954612  DT.92470896  DT.100700601  DT.91870787 
    DT.121466365  DT.92470903  DT.95267689  DT.100700590  DT.100700596  DT.120762244  DT.121466486  DT.91801712 
    DT.92359426  DT.95267669  DT.95267672  DT.100060609  DT.120762238  DT.120762240  DT.121466401  DT.121466409 

    Selected AceView cDNA sequences (see all 32):

    BC027617 NM_030979 CD243801 AA954581 AL040749 AL136900 CD358574 AF132026 
    BI464014 BI825788 AL040750 AL040794 AL046737 BG718483 BG717008 BU567424 
    AI025825 CD358948 BI460001 AA382298 CD358457 BG723981 BE091857 BF349176 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PABPC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGTTGGAGA
    PABPC3 Expression
    About this image


    PABPC3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Bone (Muscoskeletal System)
             Bone Marrow
    PABPC3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PABPC3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.458280

    UniProtKB/Swiss-Prot: PABP3_HUMAN, Q9H361
    Tissue specificity: Testis specific

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PABPC3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for PABPC3 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves PABPC16
    Gallus gallus poly(A) binding protein, cytoplasmic...
    91(a)
    1 → many
    2(128374641-128383801)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    86(a)
    1 → many
    GL343394.1(21981-42069)
    zebrafish
    (Danio rerio)
    Actinopterygii pabpc1a1 poly A binding protein, cytoplasmic 1 a 73.75(n)
    83.87(a)
      606498  NM_001031676.1  NP_001026846.1 
            Species with no ortholog for PABPC3

    ENSEMBL Gene Tree for PABPC3 (if available)
    TreeFam Gene Tree for PABPC3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PABPC3 gene
    PABPC1L2  PABPC52  PABPC42  ELAVL12  PABPC4L2  ELAVL42  RBMS12  ELAVL32  
    RBMS32  ELAVL22  RBMS22  PABPC12  
    15 SIMAP similar genes for PABPC3 using alignment to 3 protein entries:     PABP3_HUMAN (see all proteins):
    RLIM    PABPC1    PABPC1L2A    PABPC1L2B    PABPC4L    PABPC4
    PABPC5    PABPC1L    DKFZp547H118    SF3B4    ELAVL2    HNRNPA1
    TIAL1    TIA1    RBM4B

    PABPC3 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for PABPC3
    PGOHUM00000240029 PGOHUM00000245501


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PABPC3 (see all 210)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 13 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1871604451,2
    --25668351(+) TAAATC/TATAGG 1 -- us2k10--------
    rs606489091,2
    C,F--25668419(+) ATATTC/ACGTGG 1 -- us2k12Minor allele frequency- A:0.14WA 120
    rs1485523121,2
    --25668647(+) TTTAAA/CCTTTT 1 -- us2k10--------
    rs95511771,2
    C,F,A,H--25668725(+) CTCACT/GCCTGT 1 -- us2k112Minor allele frequency- G:0.40NA WA CSA EA 378
    rs1419383221,2
    --25668736(+) AATCCC/TAGAGC 1 -- us2k10--------
    rs358661021,2
    C--25668749(+) TGGCAG/AGCGTA 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs30022111,2
    C,F,A,H--25669061(+) CCCCCC/AAACTG 1 -- us2k126Minor allele frequency- A:0.28NS EA NA WA CSA 2710
    rs1916094701,2
    --25669220(+) TGACCG/TCAAAA 1 -- us2k10--------
    rs1461319041,2
    C--25669467(+) CGCTTC/GAACCT 1 -- us2k10--------
    rs1837099821,2
    --25669542(+) AACTCC/TGTCTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PABPC3 (25670276 - 25673389 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for PABPC3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2747161CNV Deletion23290073
    esv2659512CNV Deletion23128226
    dgv7e24CNV Loss17666407
    nsv899942CNV Gain21882294
    nsv435952OTHER Inversion17901297

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PABPC3
    DNA2.0 Custom Variant and Variant Library Synthesis for PABPC3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604680    OMIM disorders: --

    4 diseases for PABPC3:    
    About MalaCards
    tonsillitis    hiv-1    cerebritis    prostatitis


    PABPC3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): PABPC3

    Export disorders for PABPC3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PABPC3 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with PABPC3)
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    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    3. Human testis expresses a specific poly(A)-binding protein. (PubMed id 11328870)1, 2 Feral C.... Pawlak A. (Nucleic Acids Res. 2001)
    4. Chromosomal localization of three human poly(A)-binding protein genes and four related pseudogenes. (PubMed id 10543404)1, 3 FAcral C....GuellaAn G. (Hum. Genet. 1999)
    5. Localization of the human poly(A)-binding protein gene (PAB1) to chromosomal regions 3q22-q25, 12q13-q14, and 13q12-q13 by in situ hybridization. (PubMed id 8432538)1, 3 Morris C.M. and Bodger M.P. (Genomics 1993)
    6. Profiling of Parkin-binding partners using tandem affinity purification. (PubMed id 24244333)1 Zanon A....Pichler I. (PLoS ONE 2013)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5042 HGNC: 8556 AceView: PABPC3 Ensembl:ENSG00000151846 euGenes: HUgn5042
    ECgene: PABPC3 Kegg: 5042 H-InvDB: PABPC3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PABPC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PABPC3 gene:
    Search GeneIP for patents involving PABPC3

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