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Aliases &
Descriptions
for PABPC1L2B
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| PABPC1L2 3 | | RBM32A 3 | | RBM32B 2, 3 |
| | | Descriptions |
|---|
| RNA binding motif protein 32B 1, 2 | | RNA-binding motif protein 32 3 | | RNA-binding protein 32 3 | | poly(A) binding protein, cytoplasmic 1-like 2B 2 |
|
| |
Search outside databases for aliases for PABPC1L2B gene |
Summaries
for PABPC1L2B(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| -- |
Genomic Location
for PABPC1L2B
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq13.1 Ensembl cytogenetic band: Xq13.1 HGNC cytogenetic band: Xq13.1PABPC1L2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP072139:
(about GC identifiers)
Start:
|
72,140,077 bp from pter |
End:
|
72,142,276 bp from pter |
Size:
|
2,200 bases |
Orientation:
|
plus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011669.16
| Proteins
for PABPC1L2B
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
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| UniProtKB/Swiss-Prot: PAP1M_HUMAN, Q5JQF8 (See
protein sequence)Recommended Name: Polyadenylate-binding protein 1-like 2 Size: 200 amino acids; 22799 Da
Miscellaneous: May be not functional as it lacks the poly(A)-binding protein C-terminal (PABC)
domain implicated in the mRNA stability and translation regulation
Secondary accessions: B2RMV9 Q8IVU8Post-translational modifications:
View phosphorylation sites using PhosphoSite2
REFSEQ proteins: NP_001035971.1
ENSEMBL proteins: ENSP00000362621
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
Antibodies for PABPC1L2B:
Assays for PABPC1L2B: | Protein
Domains/
Families
for PABPC1L2B(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q5JQF8
ProtoNet protein and cluster: Q5JQF8 UniProtKB/Swiss-Prot: PAP1M_HUMAN, Q5JQF8Similarity: Contains 2 RRM (RNA recognition motif) domains | Gene Function
for PABPC1L2B
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001042506
 Applied Biosystems Silencer® siRNAs for PABPC1L2B
 Sigma-Aldrich siRNA for PABPC1L2B
Sigma-Aldrich shRNA for PABPC1L2B
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001042506
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001042506
untagged cDNA clone in CMV expression vector: NM_001042506
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_001042506
2 Gene Ontology (GO) molecular function terms (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000166 | nucleotide binding |
IEA | -- | | GO:0003723 | RNA binding |
IEA | -- |
About this table | Pathways & Interactions
for PABPC1L2B
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
-- |
Drugs & Compounds
for PABPC1L2B(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for PABPC1L2B
|
Transcripts
for PABPC1L2B(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001042506
Sigma-Aldrich siRNA for PABPC1L2B
Sigma-Aldrich shRNA for PABPC1L2B
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001042506 REFSEQ mRNAs for PABPC1L2B gene: NM_001042506.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001042506
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001042506
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001042506
untagged cDNA clone in CMV expression vector: NM_001042506
Additional cDNA sequence: BC041956.1 2 DOTS entries: DT.95305166 DT.40272099 Unigene Cluster for PABPC1L2B: Poly(A) binding protein, cytoplasmic 1-like 2B Hs.567854 [show with all ESTs]Unigene Representative Sequence: BC041956
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000373521
|
Expression
for PABPC1L2B
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| PABPC1L2B expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for PABPC1L2B
1 / 2 1 probe-set matching PABPC1L2B gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.567854
|
Orthologs
for PABPC1L2B
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for PABPC1L2B gene from 3 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
cow
(Bos taurus) |
LOC7844381 |
-- |
similar to PABPC1L2B protein |
95(n)
98.5(a) |
784438 XM_001252745.1 XP_001252746.1 |
rat
(Rattus norvegicus) |
Pabpc1l2b1 |
-- |
poly(A) binding protein, cytoplasmic 1-like 2B |
91.29(n)
93.47(a) |
302405 XM_228576.3 XP_228576.2 |
mouse
(Mus musculus) |
Pabpc1l2b5
Pabpc1l2a1 |
X5
|
poly(A) binding protein, cytoplasmic 1-like 2B5
poly(A) binding protein, cytoplasmic 1-like 2A1 |
91.45(n)1
94.36(a)1 |
2455451 XM_141989.61 XP_141989.41 |
About this table Species with no ortholog for PABPC1L2B
ENSEMBL Gene Tree for PABPC1L2B | Paralogs
for PABPC1L2B(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for PABPC1L2B gene
- PABPC1L2A1 2 PABPC1L2 PABPC32 PABPC52 PABPCP52 PABPCP22 PABPC42
|
SNPs/Variants
for PABPC1L2B(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
The following additional 6 SNP(s) have been
found in Applied Biosystems data source:
(Click
for
Applied Biosystems TaqMan ® Genotyping Assay)
HapMap Linkage Disequilibrium images for PABPC1L2B (up to first 250kb)
|
Disorders & Mutations
for PABPC1L2B
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
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| -- |
Medical News
for PABPC1L2B(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for PABPC1L2B (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 3 PubMed articles for PABPC1L2B gene: |
Search for PABPC1L2B
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PABPC1L2B
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing PABPC1L2B
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PABPC1L2B(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for PABPC1L2B(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for PABPC1L2B:
|
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Incremental update: 13 Oct 2009
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