PA2G4 Gene
protein-coding GIFtS: 61
GCID: GC12P056498
|
|
proliferation-associated 2G4, 38kDa(Previous names: proliferation-associated 2G4, 38kD )
| |
Aliases
for PA2G4 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Proliferation-Associated 2G4, 38kDa1 2 | | ErbB-3 Binding Protein 12 | | Cell Cycle Protein P38-2G4 Homolog2 3 | | ErbB3-Binding Protein Ebp12 | | ErbB3-Binding Protein 12 3 | | P38-2G41 | | EBP12 3 | | Proliferation-Associated Protein 2G42 | | Proliferation-Associated 2G4, 38kD1 | | HG4-12 | | HG4-12 | | |
Export aliases for PA2G4 gene to outside databasesPrevious GC identifers: GC12M056378 GC12M056832 GC12P056215 GC12P054784 GC12P053543 |
Summaries
for PA2G4 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PA2G4:
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present inpre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediateand late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and maycontribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgenreceptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases.This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Sixpseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80Function: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation.Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG).Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity.Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolarRNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosomeassembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity)
Gene Wiki entry for PA2G4
|
Genomic Views
for PA2G4 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000012.11 NC_018923.1 NT_029419.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PA2G4 gene promoter:
AP-1 Tal-1beta Egr-4 Egr-2 CREB HOXA5 deltaCREB SEF-1 (1) ITF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for PA2G4
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PA2G4 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12q13.2 Ensembl cytogenetic band: 12q13.2 HGNC cytogenetic band: 12q13.2PA2G4 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12P056498: view genomic region
(about GC identifiers)
Start:
|
56,498,103 bp from pter |
End:
|
56,507,694 bp from pter |
Size:
|
9,592 bases |
Orientation:
|
plus strand |
|
Proteins
for PA2G4 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80 (See
protein sequence)Recommended Name: Proliferation-associated protein 2G4 Size: 394 amino acids; 43787 Da
Subunit: Interacts with the cytoplasmic domain of non-phosphorylated ERBB3; the interaction requires PKC activity.Interacts with AR. Treatment with HRG leads to dissociation from ERBB3 and increases association with AR. Interactswith NCL/nucleolin. Component of a ribonucleoprotein complex containing at least PA2G4, NCL, TOP1, PABPC2, RPLP0,acetylated histone H1 (HIST1H1A or H1F1), histone H1 2/4, RPL4, RPL8, RPL15, RPL18, RPL18A, RPL21, RPL11, RPL12,RPL28, RPL27, RPLP2 and RPL24. Interacts with HDAC2. Interacts with RB1; the interaction is enhanced upon PA2G4dephosphorylation
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Tranlocates to the nucleus upon treatment with HRG
Caution: Although it belongs to the peptidase M24 family, it does not contain metal cofactors and lacks aminopeptidaseactivity
Sequence caution: Sequence=AAD00646.1; Type=Erroneous initiation;
2 PDB 3D structures from  and Proteopedia  for PA2G4:2Q8K (3D)
3J2I (3D)
Secondary accessions: O43846 Q9UM59Explore the universe of human proteins at neXtProt for PA2G4: NX_Q9UQ80
Post-translational modifications:
Phosphorylated on serine and threonine residues. Phosphorylation is enhanced by HRG treatment. Basal phosphorylation isPKC-dependent and HRG-induced phosphorylation is predominantly PKC-independent1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UQ80
PA2G4 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006182.2
ENSEMBL proteins: ENSP00000302886 ENSP00000448557 ENSP00000448081 ENSP00000448726 ENSP00000447615 ENSP00000447389
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
PA2G4 for ontologies About GeneDecksing
PA2G4 Antibody Products:
Assay Products for PA2G4: |
Protein
Domains /
Families
for PA2G4 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PA2G4 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9UQ80ProtoNet protein and cluster: Q9UQ80 UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80Similarity: Belongs to the peptidase M24 family |
Function
for PA2G4 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80Function: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation.Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG).Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity.Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolarRNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosomeassembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity) Genatlas biochemistry entry for PA2G4:murine cell-cycle P38-2G4 homolog,confined to the nucleus during interphase and cytoplasmic from metaphase through totelophase,widely expressed
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PA2G4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PA2G4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PA2G4 (NM_006191) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PA2G4 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PA2G4 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PA2G4 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
PA2G4 for ontologies About GeneDecksing
Animal Models:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Pa2g4):
PA2G4 for phenotypes About GeneDecksing
|
Pathways & Interactions
for PA2G4 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Coregulation of Androgen receptor activity | |
1  BioSystems Pathway for PA2G4
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PA2G4
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/77 Interacting proteins for PA2G4 (Q9UQ801, 2, 3 ENSP000003028864) via UniProtKB, MINT, STRING, and/or I2D (see all 77)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| NCL | P193381, 3, ENSP000003181954 | EBI-924893,EBI-352553 I2D:
score=2 STRING: ENSP00000318195 | | RB1 | P064001, 3, ENSP000002671634 | EBI-924893,EBI-491274 I2D:
score=4 STRING: ENSP00000267163 | | SIN3A | Q96ST31, 3, ENSP000003536224 | EBI-924893,EBI-347218 I2D:
score=3 STRING: ENSP00000353622 | | AR | P102753, ENSP000003638224 | I2D:
score=3 STRING: ENSP00000363822 | | NRBF2 | Q96F243, ENSP000002777464 | I2D:
score=3 STRING: ENSP00000277746 |
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
PA2G4 for ontologies About GeneDecksing
|
Drugs & Compounds
for PA2G4 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PA2G4 for compounds About GeneDecksing
 Browse Tocris compounds for PA2G4
1 Novoseek chemical compound relationship for PA2G4 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| testosterone |
32.1 |
9 |
15583694 (3), 12165860 (2), 18852121 (2), 19025630 (1) |
Search CenterWatch for drugs/clinical trials and news about PA2G4
|
Transcripts
for PA2G4 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PA2G4 gene: NM_006191.2 Unigene Clusters for PA2G4: Proliferation-associated 2G4, 38kDa Hs.524498 [show with all ESTs], Hs.573018 [show with all ESTs]Unigene Representative Sequences: NM_006191, NR_0032849 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000303305(uc001sjm.3) ENST00000552766 ENST00000546435 ENST00000548711
ENST00000553057 ENST00000551061 ENST00000550166 ENST00000552528 ENST00000552266
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PA2G4 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PA2G4
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PA2G4 (NM_006191) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PA2G4 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PA2G4 |
Additional cDNA sequence: AK025367.1 NR_003284.1 U50137.1 24/44 DOTS entries (see all 44): DT.91774612 DT.100034293 DT.86995864 DT.100865789 DT.92363174 DT.100687060 DT.97867576 DT.100687069 DT.100687071 DT.91670398 DT.97864060 DT.91774599 DT.91774615 DT.100687065 DT.419579 DT.91763237 DT.95340993 DT.100845158 DT.100687052 DT.95340889 DT.100687059 DT.100759294 DT.100877072 DT.121158859 24/780 AceView cDNA sequences (see all 780): BU507959 AU130268 CB160402 BM772166 BQ026946 CD622123 BM558794 BE251347 BM476310 CA311901 BQ894269 BI092808 BM556750 BI090543 CR605970 BF984460 AU120518 AA479876 BX396267 BQ437639 AA312738 BM844706 CF272275 BG251242
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for PA2G4 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PA2G4
|
Expression
for PA2G4 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PA2G4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CGGATAACCA
About this image
See PA2G4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PA2G4
SOURCE GeneReport for Unigene clusters: Hs.524498 Hs.573018
UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80Tissue specificity: Expressed in several cell lines tested, including primary and transformed cell lines
SABiosciences Custom PCR Arrays for PA2G4
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PA2G4
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PA2G4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PA2G4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PA2G4 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PA2G4 |
Orthologs
for PA2G4 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for PA2G4 gene from 8/36 species (see all 36) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
PA2G41 |
proliferation-associated 2G4, 38kDa |
81.14(n)
91.76(a) |
|
425279 XM_423059.3 XP_423059.3 |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
89(a) |
1 → many |
GL343198.1(3725287-3740819) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.89072 |
Xenopus laevis, Similar to proliferation-associated more |
82.1(n) |
|
BC044287.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufb37h042 |
Danio rerio proliferation-associated protein 1, mRNA more |
79.25(n) |
|
BC056591.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG105761 , 3 |
methionyl aminopeptidase3
CG105761 |
56(a)3
57.53(n)1
55.35(a)1 |
|
64E63
386451 NM_139727.21 NP_647984.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
W08E12.71 , 3 |
peptidase3
Protein W08E12.71 |
50(a)3
54.14(n)1
49.19(a)1 |
|
IV(3295147-3296523)3
1770971 NM_067910.51 NP_500311.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ATG21 |
metallopeptidase M24 domain-containing protein |
56.28(n)
50.52(a) |
|
824343 NM_115039.3 NP_190748.1 |
rice
(Oryza sativa) |
Liliopsida |
Os05g03505001 |
hypothetical protein |
57.02(n)
50.94(a) |
|
4338500 NM_001061809.1 NP_001055274.1 |
ENSEMBL Gene Tree for PA2G4 (if available)
TreeFam Gene Tree for PA2G4 (if available) |
Paralogs
for PA2G4 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PA2G4 gene
- ENSG000002574112 METAP22
1 SIMAP similar gene for PA2G4 using alignment to 8 protein entries: PA2G4_HUMAN (see all proteins):METAP2
PA2G4 for paralogs About GeneDecksing
5/6 Pseudogenes.org Pseudogenes for PA2G4 (see all 6)
PGOHUM00000261251 PGOHUM00000247594 PGOHUM00000237834 PGOHUM00000243332 PGOHUM00000236689
|
Genomic Variants
for PA2G4 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 12 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PA2G4 (56498103 - 56507694 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PA2G4: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PA2G4 |
|
Disorders
/ Diseases
for PA2G4 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PA2G4 for disorders About GeneDecksing
OMIM gene information: 602145
OMIM disorders: --
12  diseases for PA2G4: About MalaCardsadenoid cystic carcinoma oral squamous cell carcinoma squamous cell carcinoma adenoiditis
prostate cancer breast cancer colon cancer influenza
prostatitis carcinoma malaria neuronitis
4 Novoseek disease relationships for PA2G4 gene About this table
Export disorders for PA2G4 gene to outside databases
|
Publications
for PA2G4 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PA2G4 gene, integrated from 9 sources (see all 82):
(articles sorted by number of sources associating them with PA2G4) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and mapping of a human cDNA (PA2G4) that encodes a protein highly homologous to the mouse cell cycle protein p38-2G4. (PubMed id 9345902)1, 2, 3, 9 Lamartine J.... Sylla B.S. (1997)
- Ebp1, an ErbB-3 binding protein, interacts with Rb and affects Rb transcriptional regulation. (PubMed id 11268000)1, 2, 9 Xia X.... Hamburger A.W. (2001)
- Interaction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulin. (PubMed id 10682683)1, 2, 9 Yoo J.Y....Hamburger A.W. (2000)
- Specificity and heregulin regulation of Ebp1 (ErbB3 binding protein 1) mediated repression of androgen receptor signalling. (PubMed id 15583694)1, 2, 9 Zhang Y. and Hamburger A.W. (2005)
- Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases. (PubMed id 12682367)1, 2, 9 Zhang Y.... Hamburger A.W. (2003)
- The crystal structure of Ebp1 reveals a methionine aminopeptidase fold as binding platform for multiple interactions. (PubMed id 17765895)1, 2, 9 Kowalinski E....Sinning I. (2007)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- EBP1 is a nucleolar growth-regulating protein that is part of pre- ribosomal ribonucleoprotein complexes. (PubMed id 15064750)1, 2 Squatrito M.... Draetta G.F. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
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External Searches for PA2G4 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
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Genome Databases showing PA2G4 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing PA2G4 gene
(According to HUGE)
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Specialized Databases showing PA2G4 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Patent Information for PA2G4 gene:
Search GeneIP for patents involving PA2G4
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for PA2G4 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | OriGene Antibodies for PA2G4 | | OriGene shRNA RFP for PA2G4 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PA2G4 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PA2G4 | | | OriGene Protein Over-expression Lysate for PA2G4 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PA2G4 | | OriGene 3'-UTR Clone for PA2G4 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PA2G4 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PA2G4 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PA2G4 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PA2G4 | | OriGene Custom Protein Services for PA2G4 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PA2G4 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PA2G4 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PA2G4 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PA2G4 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PA2G4 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PA2G4 |
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| | | | Search Tocris compounds for PA2G4 |
| |  |  |  |  | | | | | | Recombinant Protein for PA2G4 |
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 | | | PA2G4 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PA2G4 |
|  |  |  | | | | ThermoFisher Antibodies for PA2G4 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PA2G4 |
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