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PA2G4 Gene

protein-coding   GIFtS: 65

GC12P054784
proliferation-associated 2G4, 38kDa
(Previous names: proliferation-associated 2G4, 38kD )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
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Aliases &
Descriptions
for PA2G4

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
EBP1 2, 3
HG4-1 2
hG4-1 3
p38-2G4 2
Descriptions
Cell cycle protein p38-2G4 homolog 2, 3
ErbB-3 binding protein 1 2
ErbB3-binding protein 1 2, 3
ErbB3-binding protein Ebp1 2
proliferation-associated 2G4, 38kD 1
proliferation-associated 2G4, 38kDa 2
External Ids
HGNC: 85501
Entrez Gene: 50362
UniProtKB: Q9UQ803
Ensembl: ENSG000001705157
Search outside databases for aliases for PA2G4 gene

Previous GC identifers: GC12M056378 GC12M056832 GC12P056215

Summaries
for PA2G4

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

 EntrezGene summary for PA2G4:
This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is
present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and
the regulation of intermediate and late steps of rRNA processing. This protein can interact with
the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory
signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes
and other cell cycle regulatory genes through its interactions with histone deacetylases. This
protein has been implicated in growth inhibition and the induction of differentiation of human
cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified.
[provided by RefSeq]

UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80
Function: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in
growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3
ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters,
probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and
5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in
regulation of intermediate and late steps of rRNA processing. May be involved in ribosome
assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry
site) (By similarity)

Gene Wiki entry for PA2G4

Genomic Location
for PA2G4

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the PA2G4 gene  

Entrez Gene cytogenetic band: 12q13.2   Ensembl cytogenetic band:  12q13.2   HGNC cytogenetic band: 12q13.2

PA2G4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P054784:     (about GC identifiers)

Start:
 54,784,370 bp from pter
End:
 54,793,961 bp from pter
Size:
 9,592 bases
Orientation:
 plus strand
RefSeq DNA sequence:
NC_000012.10  NT_029419.11  

Proteins
for PA2G4

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80 (See protein sequence)
Recommended Name: Proliferation-associated protein 2G4  
Size: 394 amino acids; 43787 Da
Subunit: Interacts with the cytoplasmic domain of non-phosphorylated ERBB3; the interaction
requires PKC activity. Interacts with AR. Treatment with HRG leads to dissociation from ERBB3 and
increases association with AR. Interacts with NCL/nucleolin. Component of a ribonucleoprotein
complex containing at least PA2G4, NCL, TOP1, PABPC2, RPLP0, acetylated histone H1 (HIST1H1A or
H1F1), histone H1 2/4, RPL4, RPL8, RPL15, RPL18, RPL18A, RPL21, RPL11, RPL12, RPL28, RPL27, RPLP2
and RPL24. Interacts with HDAC2. Interacts with RB1; the interaction is enhanced upon PA2G4
dephosphorylation
Subcellular location: Cytoplasm. Nucleus, nucleolus. Note=Tranlocates to the nucleus upon treatment
with HRG
Miscellaneous: Does not contain metal cofactors and does not have aminopeptidase activity
PDB structures from and Proteopedia :
2Q8K (3D)    
Secondary accessions: O43846 Q9UM59

Post-translational modifications:

  • Phosphorylated on serine and threonine residues. Phosphorylation is enhanced by HRG treatment.
    Basal phosphorylation is PKC-dependent and HRG-induced phosphorylation is predominantly
    PKC-independent1
  • View phosphorylation sites using PhosphoSite2


    • REFSEQ proteins: NP_006182.2  

    ENSEMBL proteins: 
    ENSP00000302886 


    Human Recombinant Proteins 
    Browse Drug Discovery Central at Invitrogen for human recombinant proteins
    Browse Purified and Recombinant Proteins at Millipore
    Sigma-Aldrich CompoZr ZFN for PA2G4  
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Recombinant Proteins from Abcam (EBP1)
    Human Recombinant Proteins from Abnova (PA2G4)
                  OriGene Purified Recombinant Human Protein: PA2G4 

    3 Gene Ontology (GO) cellular component terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634 nucleus IDA15073182
    GO:0005737 cytoplasm IEA--
    GO:0030529 ribonucleoprotein complex IEA--
    About this table

    Antibodies for PA2G4: 
    Browse Antibodies Central at Invitrogen
    Millipore Mono- and Polyclonal Antibodies for the study of PA2G4
    Sigma-Aldrich Antibodies for PA2G4
    R&D Systems Antibodies for PA2G4
    Antibodies from Abcam (EBP1), each with their AbpromiseSM
    Monoclonal and Polyclonal Antibodies from Abnova (PA2G4)
    Novus Biologicals Antibodies for PA2G4

    Assays for PA2G4: 
    Browse Invitrogen for biochemical assays
    Browse Kits and Assays available from Millipore
    Browse R&D Systems for biochemical assays
    Browse biochemical assays available from Enzo Life Sciences

    Protein Domains/
    Families
    for PA2G4

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro domains/families:
     IPR004545 Pap_1
     IPR000994 Pept_M24_structural-domain
     IPR018349 Pept_M24A_MAP2_BS


       GeneDecks  PA2G4 for the domains selected above  
    About GeneDecksing

    Graphical View of Domain Structure for InterPro Entry Q9UQ80

    ProtoNet protein and cluster: Q9UQ80

    UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80
    Similarity: Belongs to the peptidase M24 family

    Gene Function
    for PA2G4

    (According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
    shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
    RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (PA2G4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (PA2G4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006191

                  Applied Biosystems Silencer® siRNAs for PA2G4

                  Sigma-Aldrich siRNA and siRNA Panels for PA2G4  
                         Sigma-Aldrich shRNA Panels and shRNA for PA2G4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Clones:Invitrogen Clones for PA2G4
    Browse Clones for the Expression of Recombinant Proteins Available from Millipore
                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_006191
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_006191
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_006191 

    Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
                  OriGene genome-wide validated SYBR primer pairs: NM_006191

    UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80
    Function: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in
    growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3
    ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters,
    probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and
    5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in
    regulation of intermediate and late steps of rRNA processing. May be involved in ribosome
    assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry
    site) (By similarity)

    Genatlas biochemistry entry for PA2G4:
    murine cell-cycle P38-2G4 homolog,confined to the nucleus during interphase and cytoplasmic from
    metaphase through to telophase,widely expressed

    3 Gene Ontology (GO) molecular function terms (links to tree view):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700 transcription factor activity IDA15073182
    GO:0003723 RNA binding IEA--
    GO:0005515 protein binding IPI11268000 11325528 15064750 15231747 15583694 16254079 17353931
    About this table

    Pathways & Interactions
    for PA2G4

    (Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
    Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
    About This Section


    5/8 Sigma-Aldrich "Your Favorite Gene" Pathways for  PA2G4  (Your Favorite Gene powered by Ingenuity) (see all 8 ) 
     Bladder Cancer Signaling
     Small Cell Lung Cancer Signaling
     Prostate Cancer Signaling
     Non-Small Cell Lung Cancer Signaling
     Glioma Signaling

       GeneDecks  PA2G4 for the pathways selected above  
    About GeneDecksing

     Gene Network CentralTM Interacting Genes and Proteins Network for  PA2G4 


    5/25 Interacting proteins for PA2G4 (ENSP000003028863 Q9UQ801, 2) via UniProtKB, MINT, and/or STRING (see all 25 )
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARP102751STRING (score=.997) EBI-924893, EBI-608057
    E2F1Q010941STRING (score=.979) EBI-924893, EBI-448924
    ERBB3P218601STRING (score=.998) EBI-924893, EBI-720706
    NCLP193381STRING (score=.955) EBI-924893, EBI-352553
    RB1P064001STRING (score=.745) EBI-924893, EBI-491274
    About this table

    5/6 Gene Ontology (GO) biological process terms (links to tree view) (see all 6 ):

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006350 transcription IEA--
    GO:0006364 rRNA processing IEA--
    GO:0006417 regulation of translation IEA--
    GO:0007050 cell cycle arrest TAS7556453
    GO:0008283 cell proliferation TAS7556453
    About this table

    Drugs & Compounds
    for PA2G4

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
    About This Section

    Browse drugs & compounds from Enzo Life Sciences
    Sigma-Aldrich Small Molecules for PA2G4:
    Activator Antagonist Agonist Inhibitor

    Browse Tocris compounds for PA2G4

    Transcripts
    for PA2G4

    (GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView,
    non coding RNAs according to RNAdb,
    ESTs according to GeneTide,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from Invitrogen, Millipore, and/or Abnova,
    siRNAs from Applied Biosystems, Sigma-Aldrich,
    shRNA from Sigma-Aldrich, OriGene,
    Tagged/untagged cDNA clones from OriGene,
    Expression Assays from Applied Biosystems)
    About This Section
    Inhib.
    RNA:    		Invitrogen RNAi Products for gene knock-down (PA2G4)
    Browse for Gene Knock-down Tools from Millipore
    Abnova Chimera RNAi Products for Gene knock-down (PA2G4)
                  OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006191

                  Sigma-Aldrich siRNA and siRNA Panels for PA2G4  
                         Sigma-Aldrich shRNA Panels and shRNA for PA2G4  
                         Explore Sigma-Aldrich super-pooled esiRNAs  

    Applied Biosystems Silencer® siRNAs: 

    NM_006191  

    REFSEQ mRNAs for PA2G4 gene: 

    NM_006191.2   

    Applied Biosystems TaqMan ® Gene Expression Assays: 

    NM_006191  

                  OriGene GFP tagged cDNA clone in CMV expression vector: NM_006191
                                     Myc/DDK tagged cDNA clone in CMV expression vector: NM_006191
                                     untagged cDNA clones in CMV expression vector (see all 2): NM_006191 

    Additional cDNA sequence: 

    AK025367.1 U50137.1 

    24/43 DOTS entries (see all 43 ):

    DT.91774612  DT.100034293  DT.86995864  DT.100865789  DT.100687060  DT.92363174  DT.97867576  DT.100687069 
    DT.100687071  DT.91670398  DT.97864060  DT.91774615  DT.91774599  DT.419579  DT.100687052  DT.91763237 
    DT.95340993  DT.100687065  DT.100877072  DT.455557  DT.95340889  DT.100687059  DT.100759294  DT.121158859 

    24/780 AceView cDNA sequences (see all 780 ):

    CR591363 BU542868 BQ894444 AA988170 CB152588 AU142335 CB160402 BI092808 
    BU192021 BM842687 BQ000071 BU553213 BG289558 CF144455 BU501482 AI651014 
    CR595504 BM558794 BX396366 BQ877604 BU172427 BE466051 BQ678003 CR600047 

    highest scoring ESTs for PA2G4:

    U87954 AA074628 AA081122 AA081168 AA147141 AA155786 AA190417 AA346930 AA381325 AA381389 

    Unigene Clusters for PA2G4:

    Proliferation-associated 2G4, 38kDa
    Hs.524498  [show with all ESTs], Hs.715674  [show with all ESTs]
    Unigene Representative Sequences: NM_006191, AK025367


    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PA2G4

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13
    SP1:                    -                                                                                       
    SP2:              -     -                                                                                       
    SP3:                                                                                                            
    SP4:                                                                                                            

    About this scheme

    ECgene alternative splicing isoforms for PA2G4

    1 Ensembl transcript including schematic representation:
    ENST00000303305  

    Expression
    for PA2G4

    (Experimental results according to 1GeneNote and GNF BioGPS,
    probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
    Expression Assays from Applied Biosystems )
    About This Section

    PA2G4 expression in normal and diseased human tissues

     Applied Biosystems TaqMan ® Gene Expression Assays for PA2G4

    1 / 2 / 3

    6 probe-sets matching PA2G4 gene


    		Affymetrix
    probe-set    		 Array  GeneAnnot data GeneNote data GeneTide data
    # genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank

    		41600_at2, 3 U95-A 1 1.00 1.00 0.79 0.79 U87954 1.00 0.90 0.95 1

    		80456_s_at2, 3 U95-E 1 1.00 1.00 0.59 1.22 AI673444 0.60 1.00 0.82 1

    		214794_at2, 3 U133-A 1 1.00 1.00 -- -- BF669264 0.80 0.88 0.84 1

    		208676_s_at2, 3 U133-A 4 1.00 0.73 -- -- U87954 1.00 0.90 0.95 1

    		214794_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

    		208676_s_at2 U133Plus2 4 1.00 0.73 -- -- -- -- -- -- --
    About this table
    Data from (Publications) and GNF BioGPS
        About these images
    About these images

    CGAP SAGE TAG: --

    SOURCE GeneReport for Unigene clusters: Hs.524498 Hs.715674

    Expression variation in blood from EXPOLDB for PA2G4

    UniProtKB/Swiss-Prot: PA2G4_HUMAN, Q9UQ80
    Tissue specificity: Expressed in several cell lines tested, including primary and transformed cell
    lines

    Orthologs
    for PA2G4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
    About This Section
    Orthologs for PA2G4 gene from 5/22 species (see all 22 )
    Organism Gene Locus Description Human
    Similarity    		 NCBI accessions
    dog
    (Canis familiaris)    		 PA2G41   -- proliferation-associated 2G4, 38kDa 96.53(n)
    99.75(a)    		 474396  XM_531629.2  XP_531629.2 
    chimpanzee
    (Pan troglodytes)    		 PA2G41   -- proliferation-associated 2G4, 38kDa 99.83(n)
    100(a)    		 467034  XM_001169403.1  XP_001169403.1 
    cow
    (Bos taurus)    		 PA2G41   -- proliferation-associated 2G4, 38kDa 95.85(n)
    99.75(a)    		 540272  NM_001034699.1  NP_001029871.1 
    rat
    (Rattus norvegicus)    		 Pa2g41   -- proliferation-associated 2G4 91.88(n)
    98.98(a)    		 288778  NM_001004206.1  NP_001004206.1 
    mouse
    (Mus musculus)    		 Pa2g41, 5 105
    		 proliferation-associated 2G41, 5 92.13(n)1
    98.98(a)1    		 188131  NM_011119.31  NP_035249.11 
     AA6729395  AK0026855  (see all 22)
    About this table        Species with no ortholog for PA2G4

    ENSEMBL Gene Tree for PA2G4

    Paralogs
    for PA2G4

    (Paralogs according to 1HomoloGene
    and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
    About This Section

    Paralogs for PA2G4 gene
    METAP22  

    Pseudogenes
    6 related pseudogenes


    SNPs/Variants
    for PA2G4

    (According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
    About This Section


    10/37 NCBI SNPs in PA2G4 are shown (see all 37 )
    (Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 30)
    ABGenomic DataTranscription DataAllele Frequencies
    SNP IDValidChr 12 posSequenceRecsAA
    Chg    		TypeMoreRecsAllele
    freq    		PopTotal
    sample    		More
    ------------
    rs37590941,2
    		A,C,F54784170(+) TTCGCC/TAGCCG 1 -- ng514Minor allele frequency- T:0.33EA NA 1056
    rs7731211,2
    		C,F54784508(-) CGCTCC/TTAAGC 1 -- ut511Minor allele frequency- T:0.16MN 184
    rs44759531,2
    		H54783946(-) TAAGGG/TAAGTG 1 -- ng514Minor allele frequency- T:0.00EU EA WA 414
    rs37590951,2
    		H54784205(+) ACCCAG/CCCTCC 1 -- ng514Minor allele frequency- C:0.00EU EA WA 404
    rs7731201,2
    		A,C,F,H54789193(-) TGAGCG/Attttt 1 -- int14Minor allele frequency- A:0.16EU EA WA 420
    rs122978421,2
    		H54792837(+) AGAAAC/GTGACA 1 -- int14Minor allele frequency- G:0.00EU EA WA 410
    --
    rs352278251,2
    		--54794066(+) AACGA-/GGGAAT 1 -- ng310--------
    --
    rs128275221,2
    		--54783899(+) TTTTAA/TTTTTT 1 -- ng51 tfbs30--------
    --
    rs115490911,2
    		--54784870(+) ACATCA/GCCAAC 1 A/T mis10--------
    --
    rs348926451,2
    		--54784209(+) AGCCTA/CCCCGA 1 -- ng510--------
    About this table

    HapMap Linkage Disequilibrium images for PA2G4 (up to first 250kb)

    Disorders & Mutations
    for PA2G4

    (in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
    About This Section

    		 OMIM: 602145

    4 Novoseek disease relationships for PA2G4 gene

    Disease   Score   Articles   PubMed IDs for Articles with Shared Sentences (# sentences)
    prostate cancer 39.10 18 18852121 (4), 15583694 (2), 12682367 (1), 12165860 (1) (see all 5)
    retinoblastoma 36.98 2 12682367 (1)
    breast cancer 27.93 24 18283314 (5), 11268000 (3), 18355957 (3), 10797306 (2) (see all 5)
    tumors 0.00 3 12682367 (1), 17266032 (1)
    About this table

    Medical News
    for PA2G4

    (Possibly Related Articles in Doctor's Guide)
    About This Section

    		   --

    Publications
    for PA2G4

    (in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
    About This Section

    		10/46 PubMed articles for PA2G4 gene (see all 46 ):

    Search for PA2G4

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing PA2G4

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
    About This Section
    Entrez Gene: 5036 HGNC: 8550 AceView: PA2G4 Ensembl:ENSG00000170515 euGenes: HUgn5036
    ECgene: PA2G4 H-InvDB: PA2G4

    Other Databases showing PA2G4

    (According to HUGE)
    About This Section

    		   --

    Specialized Databases showing PA2G4

    (According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    ATLAS Chromosomes in Cancer entry for PA2G4 Genetics and Cytogenetics in Oncology and Haematology

    Licensable Technologies
    for PA2G4

    (Available from WIS Yeda, Salk, Tufts)
    About This Section

    		  --

    Services
    for PA2G4

    (Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
    Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
    Enzo Life Sciences, and/or Tocris Bioscience)
    About This Section



    Products for PA2G4:
     TaqMan ® Gene Expression Assays
     TaqMan ® Genotyping Assays
    		  Free SNP selection tool



      Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
      Invitrogen Antibodies  Invitrogen Assays
      Invitrogen Clones  Invitrogen Q-PCR Products
      Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
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    GeneCards Homepage    -    Last full update: 2 Jul 2009        Incremental update: 13 Oct 2009

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