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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

P2RY13 Gene

protein-coding   GIFtS: 58
GCID: GC03M151044

Purinergic Receptor P2Y, G-Protein Coupled, 13

(Previous name: G protein-coupled receptor 86)
(Previous symbols: GPR94, GPR86)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Purinergic Receptor P2Y, G-Protein Coupled, 131 2     G-Protein Coupled Receptor 862 3
GPR861 2 3 5     G-Protein Coupled Receptor 942 3
GPR941 2 3     GPCR12
G Protein-Coupled Receptor 861 2     SP1742
P2Y132 3     P2Y Purinoceptor 132

External Ids:    HGNC: 45371   Entrez Gene: 538292   Ensembl: ENSG000001816317   OMIM: 6063805   UniProtKB: Q9BPV83   

Export aliases for P2RY13 gene to outside databases

Previous GC identifers: GC03M152526 GC03M148417


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for P2RY13 Gene:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor
subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and
uridine nucleotides. This receptor is activated by ADP. (provided by RefSeq, Sep 2008)

GeneCards Summary for P2RY13 Gene: 
P2RY13 (purinergic receptor P2Y, G-protein coupled, 13) is a protein-coding gene. Diseases associated with P2RY13 include pertussis, and among its related super-pathways are Class A/1 (Rhodopsin-like receptors) and Signaling by GPCR. GO annotations related to this gene include G-protein coupled purinergic nucleotide receptor activity. An important paralog of this gene is GPR82.

UniProtKB/Swiss-Prot: P2Y13_HUMAN, Q9BPV8
Function: Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system

summary for P2RY13 Gene:
P2Y receptors are G-protein-coupled receptors that respond to extracellular purine and pyrimidine
nucleotides. To date eight mammalian P2Y receptors are known (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13
and P2Y14) as well as the non-mammalian chick p2y3, Xenopus p2y8 and turkey p2y receptors. p2y9 and p2y10
receptors are considered to be orphan receptors, and p2y5 is now known to actually be a leukotriene B4
receptor. P2Y receptor signaling is mediated through coupling to G proteins, mainly Gq/11, with P2Y12, P2Y13
and P2Y14 signaling through Gi/o. Activation of P2Y receptors initiates a wide range of signaling cascades
including PLCbeta, PLD, PLA2, AC and MAPK/MEK kinase. P2Y receptors are found in most human tissues. They
have diverse physiological roles including regulation of platelet aggregation, muscle contraction,
neurotransmission, and epithelial cell communication and migration.

Gene Wiki entry for P2RY13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the P2RY13 gene promoter:
         SRF   GR   C/EBPbeta   SRF (504 AA)   GR-beta   LUN-1   POU3F2   PPAR-alpha   GR-alpha   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidP2RY13 promoter sequence
   Search SABiosciences Chromatin IP Primers for P2RY13

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat P2RY13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q24   Ensembl cytogenetic band:  3q25.1   HGNC cytogenetic band: 3q24

P2RY13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
P2RY13 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M151044:  view genomic region     (about GC identifiers)

Start:
151,044,096 bp from pter      End:
151,047,337 bp from pter
Size:
3,242 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: P2Y13_HUMAN, Q9BPV8 (See protein sequence)
Recommended Name: P2Y purinoceptor 13  
Size: 354 amino acids; 40789 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Miscellaneous: Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and
the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl
cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins
Sequence caution: Sequence=AAH29363.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential
poly-A sequence; Sequence=AAH41116.2; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=BAG36024.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
1 PDB 3D structure from and Proteopedia for P2RY13:
2B6U (3D)    
Secondary accessions: B2R827 Q05C50 Q6DKN4 Q8IUT5 Q8TDU7 Q9BY61
Alternative splicing: 2 isoforms:  Q9BPV8-1   Q9BPV8-2   

Explore the universe of human proteins at neXtProt for P2RY13: NX_Q9BPV8

Explore proteomics data for P2RY13 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BPV8

  • P2RY13 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    P2RY13 Protein Expression
    REFSEQ proteins: NP_795713.2  
    ENSEMBL proteins: 
     ENSP00000320376  
    Reactome Protein details: Q9BPV8
    Human Recombinant Protein Products for P2RY13: 
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    Cloud-Clone Corp. Proteins for P2RY13 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IEA--
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane NAS--

    P2RY13 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    P2R: Purinergic receptors
    P2RY: GPCR / Class A : Purinergic receptors, P2Y

    IUPHAR Guide to PHARMACOLOGY protein family classification: P2Y13 receptor 
    P2Y receptors

    4 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR008109 P2Y13_purnocptor
     IPR002286 purinergic_P2Y_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q9BPV8

    ProtoNet protein and cluster: Q9BPV8

    2 Blocks protein domains:
    IPB002286 P2 purinoceptor signature
    IPB008109 P2Y13 purinoceptor signature


    UniProtKB/Swiss-Prot: P2Y13_HUMAN, Q9BPV8
    Similarity: Belongs to the G-protein coupled receptor 1 family


    P2RY13 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: P2Y13_HUMAN, Q9BPV8
    Function: Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity ----
    GO:0045028G-protein coupled purinergic nucleotide receptor activity IEA--
         
    P2RY13 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for P2RY13:
     Decreased Salmonella enterica  

         5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for P2ry13):
     cellular  digestive/alimentary  homeostasis/metabolism  liver/biliary system  skeleton 

    P2RY13 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for P2RY13: P2ry13tm1Dgen P2ry13tm1Loma

       inGenious Targeting Laboratory - Custom generated mouse model solutions for P2RY13 
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for P2RY13 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)0.71
    GPCRs, Class A Rhodopsin-like0.41
    GPCR ligand binding0.71
    Neuroactive ligand-receptor interaction0.37
    G alpha (i) signalling events0.46
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90
    3Nucleotide-like (purinergic) receptors
    Nucleotide-like (purinergic) receptors0.75
    P2Y receptors0.75
    4Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q
    Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q0.46
    5GPCRs, Other
    GPCRs, Other

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for P2RY13
        Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q


    2 BioSystems Pathways for P2RY13
        GPCRs, Other
    GPCRs, Class A Rhodopsin-like

    5/8        Reactome Pathways for P2RY13 (see all 8)
        GPCR downstream signaling
    P2Y receptors
    Signal Transduction
    Signaling by GPCR
    G alpha (i) signalling events


    1         Kegg Pathway  (Kegg details for P2RY13):
        Neuroactive ligand-receptor interaction


    P2RY13 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for P2RY13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/143 Interacting proteins for P2RY13 (ENSP000003203764) via UniProtKB, MINT, STRING, and/or I2D (see all 143)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACKR3ENSP000002729284STRING: ENSP00000272928
    ADCY2ENSP000003429524STRING: ENSP00000342952
    ADCY6ENSP000003114054STRING: ENSP00000311405
    ADORA3ENSP000003587304STRING: ENSP00000358730
    APLNRENSP000002572544STRING: ENSP00000257254
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0007194negative regulation of adenylate cyclase activity IEA--
    GO:0008150biological_process ND--

    P2RY13 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    P2RY13 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for P2RY13 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    MRS 2365Highly potent and selective P2Y1 agonist[436847-09-5]
    alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt P2 agonist[7292-42-4]
    UTPgammaS trisodium saltSelective P2Y2/4 agonist[1266569-94-1]
    MRS 2500 tetraammonium saltExtremely potent and selective P2Y1 antagonist[630103-23-0]
    MRS 2179 tetrasodium saltSelective P2Y1 antagonist[101204-49-3]

    10/15 IUPHAR Ligands for P2RY13 (P2Y13 receptor) (see all 15)    About this table 
    LigandTypeActionAffinityPubmed IDs
    [33P]2MeSADP
    AgonistFull agonist9.612815166
    2MeSADP
    AgonistFull agonist912815166
    cangrelor
    AntagonistAntagonist8.312815166
    2MeSATP
    AgonistFull agonist7.712815166
    Ap4A
    AntagonistAntagonist6.712815166
    ADP
    AgonistFull agonist6.512815166
    MRS2603
    AntagonistAntagonist6.1815913566
    MRS2211
    AntagonistAntagonist5.9715913566
    ADPβS
    AgonistFull agonist5.712815166
    reactive blue-2
    AntagonistAntagonist5.712815166

    1 Novoseek inferred chemical compound relationship for P2RY13 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adp 54.5 4 11961076 (3)

    Search CenterWatch for drugs/clinical trials and news about P2RY13 / P2Y13

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for P2RY13 gene (2 alternative transcripts): 
    NM_176894.2  NM_023914.2  

    Unigene Cluster for P2RY13:

    Purinergic receptor P2Y, G-protein coupled, 13
    Hs.546396  [show with all ESTs]
    Unigene Representative Sequence: BC041116
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000325602(uc003eyv.2)
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    Additional mRNA sequence: 

    AF178982.1 AF406692.1 AK313208.1 BC029363.1 BC041116.1 BC066887.1 JF810883.1 

    2 DOTS entries:

    DT.70104099  DT.91656824 

    24/30 AceView cDNA sequences (see all 30):

    AI129856 AI632090 AF406692 AI471697 NM_176894 NM_023914 AF295368 BX111421 
    BP339057 CD559649 AF178982 T67106 AI289619 BG621718 AF345565 AI655538 
    AI656746 BI489709 BC066887 BC029363 AI090920 BC041116 CD690381 AW295791 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    P2RY13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAATATTACC
    P2RY13 Expression
    About this image


    See P2RY13 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for P2RY13

    SOURCE GeneReport for Unigene cluster: Hs.546396

    UniProtKB/Swiss-Prot: P2Y13_HUMAN, Q9BPV8
    Tissue specificity: Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal
    cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas,
    heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly
    detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected
    in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined

        SABiosciences Expression via Pathway-Focused PCR Array including P2RY13: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for P2RY13

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for P2RY13 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia P2ry131 , 5 purinergic receptor P2Y, G-protein coupled 131, 5 80.08(n)1
    78.08(a)1
      3 (29.01 cM)5
    741911  NM_028808.31  NP_083084.21 
     592078965 
    chicken
    (Gallus gallus)
    Aves P2RY136
    Uncharacterized protein
    59(a)
    1 ↔ 1
    9(22996097-22997128)
    lizard
    (Anolis carolinensis)
    Reptilia P2RY136
    Uncharacterized protein
    60(a)
    1 ↔ 1
    3(18059975-18060985)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003295921 p2Y purinoceptor 12-like 53.84(n)
    48.9(a)
      100329592  XM_002664517.1  XP_002664563.1 


    ENSEMBL Gene Tree for P2RY13 (if available)
    TreeFam Gene Tree for P2RY13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for P2RY13 gene
    GPR822  GPR1712  GPR872  GPR342  P2RY142  P2RY122  
    9 SIMAP similar genes for P2RY13 using alignment to 2 protein entries:     P2Y13_HUMAN (see all proteins):
    P2RY12    P2RY14    GPR87    GPR171    GPR183    GPR34
    CYSLTR1    GPR17    GPR18

    P2RY13 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    1 SNPs in P2RY13 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0282994
    ----see VAR_0282992 T M mis40--------

    HapMap Linkage Disequilibrium report for P2RY13 (151044096 - 151047337 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for P2RY13:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv829757CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 606380    OMIM disorders: --

    2 diseases for P2RY13:    About MalaCards
    pertussis    


    P2RY13 for disorders           About GeneDecksing

    Genetic Association Database (GAD): P2RY13
    Human Genome Epidemiology (HuGE) Navigator: P2RY13 (3 documents)

    Export disorders for P2RY13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for P2RY13 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with P2RY13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. (PubMed id 11273702)1, 2, 3, 9 Wittenberger T.... Hellebrand S. (2001)
    2. Discovery and mapping of ten novel G protein-coupled receptor genes. (PubMed id 11574155)1, 2, 3 Lee D.K....O'Dowd B.F. (2001)
    3. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    4. Identification of G protein-coupled receptor genes from the human genome sequence. (PubMed id 12044878)1, 2 Takeda S.... Mitaku S. (2002)
    5. Identification of a novel human ADP receptor coupled to Gi. (PubMed id 11546776)1, 2 Communi D.... Boeynaems J.-M. (2001)
    6. P2Y(13): identification and characterization of a novel Galphai-coupled ADP receptor from human and mouse. (PubMed id 11961076)1, 9 Zhang F.L....Monsma F. (2002)
    7. Adenylate cyclase 5 coordinates the action of ADP, P2Y 1, P2Y13 and ATP-gated P2X7 receptors on axonal elongation. (PubMed id 22250198)1 del Puerto A....Garrido J.J. (2012)
    8. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    9. Dissociation of heterotrimeric g proteins in cells. (PubMed id 18577758)1 Lambert N.A. (2008)
    10. Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029)1 Luttrell L.M. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 53829 HGNC: 4537 AceView: P2RY13 Ensembl:ENSG00000181631 euGenes: HUgn53829
    ECgene: P2RY13 Kegg: 53829 H-InvDB: P2RY13

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for P2RY13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for P2RY13 gene:
    Search GeneIP for patents involving P2RY13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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