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P2RY10 Gene

protein-coding   GIFtS: 55
GCID: GC0XP078200

Purinergic Receptor P2Y, G-Protein Coupled, 10

  Search for P2RY10
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Purinergic Receptor P2Y, G-Protein Coupled, 101 2
P2Y102 3 5
P2Y-Like Receptor2 3
G-Protein Coupled Purinergic Receptor P2Y102
P2Y Purinoceptor 102
Putative P2Y Purinoceptor 102

External Ids:    HGNC: 199061   Entrez Gene: 273342   Ensembl: ENSG000000785897   OMIM: 3005295   UniProtKB: O003983   

Export aliases for P2RY10 gene to outside databases

Previous GC identifers: GC0XP075162 GC0XP076242 GC0XP076956 GC0XP078006 GC0XP078087 GC0XP071781


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for P2RY10 Gene:
The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially
activated by adenosine and uridine nucleotides. Two alternatively spliced transcript variants encoding the same
protein isoform have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for P2RY10 Gene:
P2RY10 (purinergic receptor P2Y, G-protein coupled, 10) is a protein-coding gene. GO annotations related to this gene include G-protein coupled purinergic nucleotide receptor activity. An important paralog of this gene is OXGR1.

UniProtKB/Swiss-Prot: P2Y10_HUMAN, O00398
Function: Putative receptor for purines coupled to G-proteins

summary for P2RY10 Gene:
P2Y receptors are G-protein-coupled receptors that respond to extracellular purine and pyrimidine
nucleotides. To date eight mammalian P2Y receptors are known (P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, P2Y13
and P2Y14) as well as the non-mammalian chick p2y3, Xenopus p2y8 and turkey p2y receptors. p2y9 and p2y10
receptors are considered to be orphan receptors, and p2y5 is now known to actually be a leukotriene B4
receptor. P2Y receptor signaling is mediated through coupling to G proteins, mainly Gq/11, with P2Y12, P2Y13
and P2Y14 signaling through Gi/o. Activation of P2Y receptors initiates a wide range of signaling cascades
including PLCbeta, PLD, PLA2, AC and MAPK/MEK kinase. P2Y receptors are found in most human tissues. They
have diverse physiological roles including regulation of platelet aggregation, muscle contraction,
neurotransmission, and epithelial cell communication and migration.

Gene Wiki entry for P2RY10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the P2RY10 gene promoter:
         AML1a   CUTL1   POU3F2   NF-kappaB   FOXJ2 (long isoform)   NF-kappaB2   FOXJ2   NF-kappaB1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidP2RY10 promoter sequence
   Search Chromatin IP Primers for P2RY10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat P2RY10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq21.1   Ensembl cytogenetic band:  Xq21.1   HGNC cytogenetic band: Xq21.1

P2RY10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
P2RY10 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP078200:  view genomic region     (about GC identifiers)

Start:
78,200,829 bp from pter      End:
78,217,451 bp from pter
Size:
16,623 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: P2Y10_HUMAN, O00398 (See protein sequence)
Recommended Name: Putative P2Y purinoceptor 10  
Size: 339 amino acids; 38774 Da
Developmental stage: Up-regulated during promyelocytic cell differentiation along the monocytic pathway, but not
during granulocytic differentiation
Secondary accessions: D3DTE5 Q4VBN7 Q86V16

Explore the universe of human proteins at neXtProt for P2RY10: NX_O00398

Explore proteomics data for P2RY10 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn16, Asn26, Asn178
  • Modification sites at PhosphoSitePlus

  • See P2RY10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_055314.1  NP_938147.1  

    ENSEMBL proteins: 
     ENSP00000171757   ENSP00000443138  
    Reactome Protein details: O00398

    P2RY10 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    P2R: Purinergic receptors
    P2RY: GPCR / Class A : Purinergic receptors, P2Y

    IUPHAR Guide to PHARMACOLOGY protein family classification: P2RY10
    Class A Orphans

    3 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR027676 P2Y10_rcpt
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry O00398

    ProtoNet protein and cluster: O00398

    UniProtKB/Swiss-Prot: P2Y10_HUMAN, O00398
    Similarity: Belongs to the G-protein coupled receptor 1 family


    P2RY10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: P2Y10_HUMAN, O00398
    Function: Putative receptor for purines coupled to G-proteins

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity ----
    GO:0045028G-protein coupled purinergic nucleotide receptor activity IEA--
         
    P2RY10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for P2RY10:
     Increased circadian period len 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for P2RY10
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    3 qRT-PCR Assays for microRNAs that regulate P2RY10:
    hsa-miR-3607-3p hsa-miR-548am hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmidP2RY10 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    P2Y10_HUMAN, O00398: Cell membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    P2RY10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for P2RY10 About    
    See pathways by source

    SuperPathContained pathways About
    1Peptide ligand-binding receptors
    Class A/1 (Rhodopsin-like receptors)0.71
    GPCRs, Class A Rhodopsin-like0.43
    GPCR ligand binding0.71
    Neuroactive ligand-receptor interaction0.36
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.58
    GPCR downstream signaling0.90
    3Gastrin-CREB signalling pathway via PKC and MAPK
    Gastrin-CREB signalling pathway via PKC and MAPK0.90
    G alpha (q) signalling events0.90
    4Nucleotide-like (purinergic) receptors
    Nucleotide-like (purinergic) receptors
    P2Y receptors0.00

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for P2RY10
        GPCRs, Class A Rhodopsin-like

    2 Reactome Pathways for P2RY10
        P2Y receptors
    G alpha (q) signalling events


    1 Kegg Pathway  (Kegg details for P2RY10):
        Neuroactive ligand-receptor interaction


    P2RY10 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Array including P2RY10: 
              G Protein Coupled Receptors 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for P2RY10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for P2RY10 (ENSP000001717574) via UniProtKB, MINT, STRING, and/or I2D (see all 123)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CYSLTR1ENSP000003624014STRING: ENSP00000362401
    CYSLTR2ENSP000002820184STRING: ENSP00000282018
    GPR17ENSP000002726444STRING: ENSP00000272644
    GPR65ENSP000002675494STRING: ENSP00000267549
    GRPRENSP000003696434STRING: ENSP00000369643
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----

    P2RY10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for P2RY10 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    MRS 2365Highly potent and selective P2Y1 agonist[436847-09-5]
    alpha,beta-Methyleneadenosine 5'-triphosphate trisodium salt P2 agonist[7292-42-4]
    UTPgammaS trisodium saltSelective P2Y2/4 agonist[1266569-94-1]
    MRS 2500 tetraammonium saltExtremely potent and selective P2Y1 antagonist[630103-23-0]
    MRS 2179 tetrasodium saltSelective P2Y1 antagonist[101204-49-3]

    4 IUPHAR Ligands for P2RY10 (P2RY10)    About this table
    LigandTypeActionAffinityPubmed IDs
    sphingosine 1-phosphate
    AgonistAgonist7.318466763
    LPA
    AgonistAgonist6.918466763
    dioctanoy?aelglycerol?ae pyrophos?aephate
    AntagonistAntagonist6.918466763
    JTE-013
    AntagonistAntagonist6.918466763



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for P2RY10 gene (2 alternative transcripts): 
    NM_014499.2  NM_198333.1  

    Unigene Cluster for P2RY10:

    Purinergic receptor P2Y, G-protein coupled, 10
    Hs.296433  [show with all ESTs]
    Unigene Representative Sequence: NM_014499
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000461541 ENST00000475374 ENST00000171757(uc004ede.3) ENST00000544091(uc004edf.3)

    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate P2RY10:
    hsa-miR-3607-3p hsa-miR-548am hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmidP2RY10 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat P2RY10
      QuantiFast Probe-based Assays in human, mouse, rat P2RY10

    Additional mRNA sequence: 

    AK292138.1 AK313218.1 BC051875.1 BC095498.1 

    4 DOTS entries:

    DT.100747872  DT.423965  DT.95365580  DT.121312156 

    18 AceView cDNA sequences:

    AA211831 BC051875 NM_198333 NM_014499 BI907046 BU429177 CD641054 CF147798 
    CD639881 BF795250 BI905912 AI922752 AA747912 AI540818 AA210739 AW499818 
    BG196295 AW976214 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for P2RY10    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d · 5e
    SP1:              -                                             
    SP2:                          -                                 
    SP3:              -     -                                       
    SP4:              -           -                                 
    SP5:              -     -     -                                 


    ECgene alternative splicing isoforms for P2RY10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    P2RY10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCAAGGAGA
    P2RY10 Expression
    About this image


    P2RY10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 3 entries
             Mature B-Cells Peripheral Blood
     
     Thymus (Hematopoietic System)
             Thymus
     
     Adipose (Muscoskeletal System)
             Body Subcutaneous White Adipose
    P2RY10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    P2RY10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.296433

    UniProtKB/Swiss-Prot: P2Y10_HUMAN, O00398
    Tissue specificity: Weakly expressed in blood leukocytes

        Pathway & Disease-focused RT2 Profiler PCR Array including P2RY10: 
              G Protein Coupled Receptors 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for P2RY10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for P2RY10 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia P2ry101 , 5 purinergic receptor P2Y, G-protein coupled 101, 5 85.42(n)1
    86.24(a)1
      X (47.43 cM)5
    788261  NM_172435.31  NP_766023.11 
     1070884925 
    chicken
    (Gallus gallus)
    Aves P2RY101 purinergic receptor P2Y, G-protein coupled, 10 68.37(n)
    68.69(a)
      422148  XM_420149.3  XP_420149.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    54(a)
    49(a)
    1 ↔ many
    1 ↔ many
    GL343528.1(234387-240404)
    GL343528.1(256781-262483)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia p2ry101 purinergic receptor P2Y, G-protein coupled, 10 62.19(n)
    61.64(a)
      100495529  XM_002937050.2  XP_002937096.1 
    zebrafish
    (Danio rerio)
    Actinopterygii p2ry101 purinergic receptor P2Y, G-protein coupled, 10 59.14(n)
    58.47(a)
      100037375  NM_001089527.1  NP_001082996.1 


    ENSEMBL Gene Tree for P2RY10 (if available)
    TreeFam Gene Tree for P2RY10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for P2RY10 gene
    OXGR12  P2RY42  GPR172  P2RY12  P2RY62  GPR1742  LPAR62  LPAR52  
    CYSLTR12  GPR1832  LPAR42  CYSLTR22  P2RY22  SUCNR12  PTAFR2  
    9 SIMAP similar genes for P2RY10 using alignment to 1 protein entry:     P2Y10_HUMAN:
    GPR174    LPAR4    LPAR6    GPR17    CYSLTR1    P2RY1
    PTAFR    P2RY2    P2RY8

    P2RY10 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for P2RY10
    PGOHUM00000241867


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for P2RY10 (see all 284)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1923120841,2
    --78170586(+) ATTGGC/TAAAAT 2 -- us2k10--------
    rs726299361,2
    C--78170604(+) CTGCAC/GTACTT 2 -- us2k10--------
    rs1426161121,2
    C--78170763(+) AGATTG/TGTTCA 2 -- us2k10--------
    rs1848689131,2
    --78170795(+) TTCATG/TCTGCT 2 -- us2k10--------
    rs1446503941,2
    --78170857(+) CAGTCC/TCATAT 2 -- us2k10--------
    rs1478671951,2
    --78170865(+) TATGGC/TTGGGG 2 -- us2k10--------
    rs1416685271,2
    --78171077(+) AACACA/GTGGGA 2 -- us2k10--------
    rs1881285701,2
    --78171151(+) TTAACA/GCTCAA 2 -- us2k10--------
    rs734998851,2
    C,F--78171326(+) AATAAT/AGTTGG 2 -- us2k13Minor allele frequency- A:0.25WA CSA 4
    rs1927890401,2
    --78171334(+) TGGGAA/TGTGGT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for P2RY10 (78200829 - 78217451 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for P2RY10: --
    Locus Specific Mutation Databases (LSDB): P2RY10

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing P2RY10
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300529    OMIM disorders: --


    P2RY10 for disorders           About GeneDecksing


    Export disorders for P2RY10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for P2RY10 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with P2RY10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Expression of purinergic receptors (ionotropic P2X1-7 and metabotropic P2Y1-11) during myeloid differentiation of HL60 cells. (PubMed id 11004484)1, 2, 3 Adrian K.... Ogilvie A. (Biochim. Biophys. Acta 2000)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Receptors for purines and pyrimidines. (PubMed id 9755289)1, 3 Ralevic V. and Burnstock G. (Pharmacol. Rev. 1998)
    5. Dissociation of heterotrimeric g proteins in cells. (PubMed id 18577758)1 Lambert N.A. (Sci Signal 2008)
    6. Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors. (PubMed id 18240029)1 Luttrell L.M. (Mol. Biotechnol. 2008)
    7. Identification of the orphan GPCR, P2Y(10) receptor as the sphingosine-1-phosphate and lysophosphatidic acid receptor. (PubMed id 18466763)1 Murakami M....Fujita N. (Biochem. Biophys. Res. Commun. 2008)
    8. Stable association between G alpha(q) and phospholipase C beta 1 in living cells. (PubMed id 16754659)1 Dowal L....Scarlata S. (J. Biol. Chem. 2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Human monocyte derived dendritic cells express functional P2X and P2Y receptors as well as ecto-nucleotidases. (PubMed id 10570953)1 Berchtold S....Steinkasserer A. (FEBS Lett. 1999)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27334 HGNC: 19906 AceView: P2RY10 Ensembl:ENSG00000078589 euGenes: HUgn27334
    ECgene: P2RY10 Kegg: 27334 H-InvDB: P2RY10

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for P2RY10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for P2RY10 gene:
    Search GeneIP for patents involving P2RY10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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