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Aliases for P2RX5-TAX1BP3 Gene

Subcategory (RNA class) for P2RX5-TAX1BP3 Gene


Quality Score for this RNA gene is


Aliases for P2RX5-TAX1BP3 Gene

  • P2RX5-TAX1BP3 Readthrough (NMD Candidate) 2 3 5

External Ids for P2RX5-TAX1BP3 Gene

Previous GeneCards Identifiers for P2RX5-TAX1BP3 Gene

  • GC17U901601
  • GC17M003569

Summaries for P2RX5-TAX1BP3 Gene

Entrez Gene Summary for P2RX5-TAX1BP3 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring P2RX5 (purinergic receptor P2X, ligand-gated ion channel, 5) and TAX1BP3 (Tax1 binding protein 3) genes on chromosome 17. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is thus unlikely to produce a protein product. [provided by RefSeq, Mar 2011]

GeneCards Summary for P2RX5-TAX1BP3 Gene

P2RX5-TAX1BP3 (P2RX5-TAX1BP3 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include ion channel activity and purinergic nucleotide receptor activity. An important paralog of this gene is P2RX5.

Additional gene information for P2RX5-TAX1BP3 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for P2RX5-TAX1BP3 Gene

Genomics for P2RX5-TAX1BP3 Gene

Regulatory Elements for P2RX5-TAX1BP3 Gene

Enhancers for P2RX5-TAX1BP3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H003690 1.2 Ensembl ENCODE 0.7 +2.3 2256 8.1 HDGF PKNOX1 SIN3A FEZF1 ZNF121 ZNF143 ZNF207 ATF7 RUNX3 MIER2 HASPIN P2RX5 P2RX5-TAX1BP3 EMC6
GH17H003710 1.4 Ensembl ENCODE dbSUPER 0.4 -15.6 -15589 3.1 HDAC1 HDGF BMI1 TCF12 ZNF121 EGR1 ATF7 ETV6 RUNX3 CREM HASPIN ENSG00000262692 P2RX5-TAX1BP3 P2RX5
GH17H003681 1.1 Ensembl ENCODE 0.4 +13.9 13911 2 HDGF RB1 KLF17 ZNF2 RAD21 ZNF143 ZNF207 ATF7 RUNX3 IKZF2 EMC6 P2RX5-TAX1BP3 P2RX5
GH17H003719 1 Ensembl ENCODE 0.3 -24.1 -24123 2.5 JUN FOSL1 NFE2 FOS TCF7L2 ZNF362 E2F5 CEBPB DPF2 EP300 HASPIN ENSG00000262692 P2RX5-TAX1BP3 P2RX5
GH17H003689 0.6 Ensembl 0.4 +6.5 6504 0.2 HDGF ZSCAN4 MNT NR3C1 TARDBP ZNF341 MLLT1 ZBTB33 P2RX5-TAX1BP3 P2RX5 EMC6
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around P2RX5-TAX1BP3 on UCSC Golden Path with GeneCards custom track

Promoters for P2RX5-TAX1BP3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000090355 304 1001 ZNF76 SIN3A ZNF143 RUNX3 SMARCA5 SMARCC1 MIER2 REST ZNF217 KLF16

Genomic Locations for P2RX5-TAX1BP3 Gene

Genomic Locations for P2RX5-TAX1BP3 Gene
33,512 bases
Minus strand

Genomic View for P2RX5-TAX1BP3 Gene

Genes around P2RX5-TAX1BP3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
P2RX5-TAX1BP3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for P2RX5-TAX1BP3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for P2RX5-TAX1BP3 Gene

Proteins for P2RX5-TAX1BP3 Gene

Post-translational modifications for P2RX5-TAX1BP3 Gene

No Post-translational modifications

Other Protein References for P2RX5-TAX1BP3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for P2RX5-TAX1BP3 Gene

Domains & Families for P2RX5-TAX1BP3 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for P2RX5-TAX1BP3 Gene

Function for P2RX5-TAX1BP3 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for P2RX5-TAX1BP3 Gene

Localization for P2RX5-TAX1BP3 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for P2RX5-TAX1BP3 gene
Compartment Confidence
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for P2RX5-TAX1BP3 Gene

Pathways & Interactions for P2RX5-TAX1BP3 Gene

SuperPathways for P2RX5-TAX1BP3 Gene

No Data Available

Interacting Proteins for P2RX5-TAX1BP3 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000455681 for P2RX5-TAX1BP3 Gene via STRING

Gene Ontology (GO) - Biological Process for P2RX5-TAX1BP3 Gene


No data available for Pathways by source and SIGNOR curated interactions for P2RX5-TAX1BP3 Gene

Drugs & Compounds for P2RX5-TAX1BP3 Gene

No Compound Related Data Available

Transcripts for P2RX5-TAX1BP3 Gene

mRNA/cDNA for P2RX5-TAX1BP3 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for P2RX5-TAX1BP3 Gene

No ASD Table

Relevant External Links for P2RX5-TAX1BP3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for P2RX5-TAX1BP3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for P2RX5-TAX1BP3 Gene

genes like me logo Genes that share expression patterns with P2RX5-TAX1BP3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for P2RX5-TAX1BP3 Gene

Orthologs for P2RX5-TAX1BP3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for P2RX5-TAX1BP3 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 99 (a)
(Canis familiaris)
Mammalia P2X5 34
  • 74 (a)
(Mus musculus)
Mammalia P2rx5 34
  • 63 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 61 (a)
(Bos Taurus)
Mammalia -- 34
  • 60 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 57 (a)
(Gallus gallus)
Aves P2RX5 34
  • 65 (a)
(Danio rerio)
Actinopterygii p2rx5 34
  • 45 (a)
p2rx8 34
  • 42 (a)
Species where no ortholog for P2RX5-TAX1BP3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for P2RX5-TAX1BP3 Gene

Gene Tree for P2RX5-TAX1BP3 (if available)
Gene Tree for P2RX5-TAX1BP3 (if available)

Paralogs for P2RX5-TAX1BP3 Gene

Paralogs for P2RX5-TAX1BP3 Gene

genes like me logo Genes that share paralogs with P2RX5-TAX1BP3: view

Variants for P2RX5-TAX1BP3 Gene

Sequence variations from dbSNP and Humsavar for P2RX5-TAX1BP3 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1128098 Likely benign 3,662,919(-) TGGTG(C/T)GCTCA nc-transcript-variant, utr-variant-3-prime
rs1128109 Likely benign 3,662,915(-) GCGCT(C/G)AATAA nc-transcript-variant, utr-variant-3-prime
rs77196744 Likely benign 3,662,484(+) CCCTC(A/G)CTGGG intron-variant, downstream-variant-500B, utr-variant-3-prime
rs1057517690 Uncertain significance 3,664,740(-) CAGCA(C/T)TGGAG nc-transcript-variant, reference, missense
rs184828971 Uncertain significance 3,662,405(+) GGTAC(A/G)CAGGT intron-variant, downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for P2RX5-TAX1BP3 Gene

Variant ID Type Subtype PubMed ID
nsv960399 CNV duplication 23825009
nsv952107 CNV deletion 24416366
nsv833342 CNV loss 17160897
nsv827860 CNV loss 20364138
nsv574262 CNV loss 21841781
nsv574246 CNV gain+loss 21841781
nsv574244 CNV loss 21841781
nsv574237 CNV loss 21841781
nsv512471 CNV loss 21212237
nsv1948 CNV deletion 18451855
nsv1947 CNV insertion 18451855
nsv111790 CNV deletion 16902084
nsv1070796 CNV deletion 25765185
nsv1065489 CNV gain 25217958
nsv1055740 CNV gain 25217958
esv3447841 CNV duplication 20981092
esv2715531 CNV deletion 23290073
esv22375 CNV gain+loss 19812545
esv2094472 CNV deletion 18987734
esv1604795 CNV deletion 17803354
esv1195616 CNV deletion 17803354
dgv5428n54 CNV loss 21841781
dgv5427n54 CNV gain 21841781
dgv5426n54 CNV gain+loss 21841781
dgv5425n54 CNV loss 21841781
dgv5424n54 CNV gain 21841781
dgv5423n54 CNV loss 21841781
dgv358n27 CNV loss 19166990
dgv3085n100 CNV loss 25217958
dgv1406n106 CNV deletion 24896259

Relevant External Links for P2RX5-TAX1BP3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for P2RX5-TAX1BP3 Gene

Disorders for P2RX5-TAX1BP3 Gene

Relevant External Links for P2RX5-TAX1BP3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for P2RX5-TAX1BP3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for P2RX5-TAX1BP3 Gene

Publications for P2RX5-TAX1BP3 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 60

Products for P2RX5-TAX1BP3 Gene

Sources for P2RX5-TAX1BP3 Gene

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