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P2RX5 Gene

protein-coding GIFtS: 59

GC17M003523

purinergic receptor P2X, ligand-gated ion channel, 5
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
MGC47755 ^²
P2X5 ^¹, ², ³
P2X5R ^²

Descriptions
ATP receptor ^³
ATP receptor subunit ^²
P2X purinoceptor 5 ^²
Purinergic receptor ^³
ionotropic ATP receptor P2X5 ^²
purinergic receptor P2X ligand gated ion channel 5 ^²
purinergic receptor P2X, ligand-gated ion channel, 5 ^²
purinergic receptor P2X5 ^²

External Ids
HGNC: 8536¹
Entrez Gene: 5026²
UniProtKB: Q93086³
Ensembl: ENSG00000083454⁷

Search outside databases for aliases for P2RX5 gene

Previous GC identifers: GC17M003890 GC17M003526 GC17M003784 GC17M003785

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for P2RX5:

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as

a ligand-gated ion channel. Several characteristic motifs of ATP-gated channels are present in its

primary structure, but, unlike other members of the purinoceptors family, this receptor has only a

single transmembrane domain. Three transcript variants encoding distinct isoforms have been

identified for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: P2RX5_HUMAN, Q93086

Function: Receptor for ATP that acts as a ligand gated ion channel

Gene Wiki entry for P2RX5

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the P2RX5 gene

Entrez Gene cytogenetic band: 17p13.3 Ensembl cytogenetic band: 17p13.3 HGNC cytogenetic band: 17p13.3

P2RX5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 17 GeneLoc Exon Structure

GeneLoc location for GC17M003523: (about GC identifiers)

Start:	3,522,497 bp from pter
End:	3,546,332 bp from pter
Size:	23,836 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000017.9 NT_010718.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: P2RX5_HUMAN, Q93086 (See protein sequence)

Recommended Name: P2X purinoceptor 5

Size: 422 amino acids; 47205 Da

Subunit: Homo- or heteropolymers (By similarity)

Subcellular location: Membrane; Multi-pass membrane protein

Sequence caution: Sequence=AAF43106.1; Type=Erroneous gene model prediction; Sequence=AK307959;

Type=Frameshift; Positions=112; Sequence=BAD92860.1; Type=Frameshift; Positions=112;

Sequence=BC028084; Type=Frameshift; Positions=112;

Secondary accessions: O43450 O75540 Q59F38 Q8IXW4 Q93087 Q9NZV0

Alternative splicing: 4 isoforms: Q93086-3 Q93086-1 Q93086-2 Q93086-4

REFSEQ proteins (3 alternative transcripts):

NP_002552.2 NP_778255.1 NP_778256.1

ENSEMBL proteins:

ENSP00000342161 ENSP00000225328 ENSP00000371255

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (P2X5b, P2X5)
	Human Recombinant Proteins from Abnova (P2RX5)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005887	integral to plasma membrane	TAS	9414125
GO:0016020	membrane	IEA	--

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Antibodies for P2RX5:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of P2RX5
	Sigma-Aldrich Antibodies for P2RX5
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (P2X5b, P2X5), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (P2RX5)
	Novus Biologicals Antibodies for P2RX5

Assays for P2RX5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q93086

ProtoNet protein and cluster: Q93086

2 Blocks protein families:

IPB001429 ATP P2X receptor

IPB003048 P2X5 purinoceptor signature

UniProtKB/Swiss-Prot: P2RX5_HUMAN, Q93086

Similarity: Belongs to the P2X receptor family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (P2RX5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (P2RX5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_002561

Applied Biosystems Silencer® siRNAs for P2RX5

Sigma-Aldrich siRNA and siRNA Panels for P2RX5

Sigma-Aldrich shRNA Panels and shRNA for P2RX5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for P2RX5
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_002561
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_002561
untagged cDNA clones in CMV expression vector (see all 3): NM_002561

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002561

UniProtKB/Swiss-Prot: P2RX5_HUMAN, Q93086

Function: Receptor for ATP that acts as a ligand gated ion channel

5/7 Gene Ontology (GO) molecular function terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001614	purinergic nucleotide receptor activity	NAS	17895406
GO:0004888	transmembrane receptor activity	TAS	9414125
GO:0004931	ATP-gated cation channel activity	NAS	17895406
GO:0005216	ion channel activity	TAS	9414125
GO:0005524	ATP binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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5/26 Interacting proteins for P2RX5 (ENSP00000371255³) via UniProtKB, MINT, and/or STRING (see all 26 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LIN7A	ENSP00000261203³	STRING (score=.943)
CNTN2	ENSP00000330633³	STRING (score=.928)
USH1C	ENSP00000005226³	STRING (score=.899)
RYR3	ENSP00000354852³	STRING (score=.87)
GRIN2C	ENSP00000338645³	STRING (score=.862)

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5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--
GO:0007165	signal transduction	TAS	9414125
GO:0007399	nervous system development	TAS	9414125
GO:0010524	positive regulation of calcium ion transport into cytosol	NAS	17895406
GO:0050850	positive regulation of calcium-mediated signaling	NAS	17895406

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Compounds for P2RX5 available from Tocris Bioscience

Compound	Action	CAS number
iso-PPADS tetrasodium salt	P2X antagonist
NF 023	Selective, competitive P2X antagonist	[104869-31-0]
2-Methylthioadenosine triphosphate tetrasodium salt	P2 purinergic agonist	[43170-89-4]
TNP-ATP triethylammonium salt	Potent, selective P2X antagonist	[61368-63-6]

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2 Novoseek chemical compound relationships for P2RX5 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
atp	66.43	5	10496954 (1), 17043813 (1), 10633863 (1), 16373435 (1)
calcium	25.69	4	17043813 (2), 18404509 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (P2RX5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (P2RX5)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_002561

Sigma-Aldrich siRNA and siRNA Panels for P2RX5

Sigma-Aldrich shRNA Panels and shRNA for P2RX5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002561 NM_175080 NM_175081

REFSEQ mRNAs for P2RX5 gene (3 alternative transcripts):

NM_002561.2 NM_175080.1 NM_175081.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002561 NM_175080 NM_175081

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_002561
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_002561
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_002561

Additional cDNA sequence:

AF016709.1 AF070573.1 AK290889.1 AK293610.1 AK307959.1 BC006220.2 BC008319.1 BC016917.1

BC028084.1 BC039015.1 CR612864.1 CR624034.1 DQ234349.1 DQ851492.1 U49395.1 U49396.1

10 DOTS entries:

DT.100777390 DT.120962919 DT.441930 DT.91864652 DT.100703680 DT.91750971 DT.213993 DT.99936057

DT.75146946 DT.86846987

24/114 AceView cDNA sequences (see all 114 ):

BI253383 AI090922 BQ217944 BQ222641 AA836604 BQ055487 BM693531 CR612864

NM_175080 BC008319 BQ270311 AI920988 CR624034 NM_175081 BC039015 BE906689

AI524622 AA327481 BM932250 AF070573 BC028084 NM_002561 BC016917 AF016709

highest scoring ESTs for P2RX5:

U49395 AF016709 AF070573 BC006220 BC008319 BC016917 BC028084 BC039015 BE791872 BI837109

Unigene Cluster for P2RX5:

Purinergic receptor P2X, ligand-gated ion channel, 5

Hs.408615 [show with all ESTs]

Unigene Representative Sequence: NM_002561

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for P2RX5

ExUns:	1a	·	1b	·	1c	·	1d	^	2a	·	2b	^	3	^	4	^	5	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11	^	12
SP1:									-
SP2:									-				-
SP3:									-				-
SP4:									-
SP5:													-

About this scheme

ECgene alternative splicing isoforms for P2RX5

3 Ensembl transcripts including schematic representations:

ENST00000345901 ENST00000225328 ENST00000381833

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

P2RX5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for P2RX5

¹ / ² / ³

3 probe-sets matching P2RX5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
40396_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U49395	0.80	1.00	0.91	1
210448_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	U49396	0.60	1.00	0.82	1
210448_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks P2RX5 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CCACTTTGGC

SOURCE GeneReport for Unigene cluster: Hs.408615
Expression variation in blood from EXPOLDB for P2RX5
UniProtKB/Swiss-Prot: P2RX5_HUMAN, Q93086
Tissue specificity: Expressed at high levels in brain and immune system

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for P2RX5 gene from 5/8 species (see all 8 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	P2RX5¹	--	purinergic receptor P2X, ligand-gated ion channel, more	81.73(n) 76.54(a)	448785 XM_548343.2 XP_548343.2
chimpanzee (Pan troglodytes)	P2RX5¹	--	purinergic receptor P2X, ligand-gated ion channel, more	98.82(n) 99.53(a)	454434 XM_511272.2 XP_511272.2
cow (Bos taurus)	P2RX5¹	--	purinergic receptor P2X, ligand-gated ion channel, more	84.23(n) 77.46(a)	338035 XM_594012.3 XP_594012.3
rat (Rattus norvegicus)	P2rx5¹	--	purinergic receptor P2X, ligand-gated ion channel, more	75.43(n) 69.59(a)	113995 NM_080780.2 NP_542958.2
mouse (Mus musculus)	P2rx5^{1, 5}	11⁵	purinergic receptor P2X, ligand-gated ion channel, more^{1, 5}	75(n)¹ 69.42(a)¹	94045¹ NM_033321.2¹ NP_201578.1¹ AF333331⁵ AF333332⁵ (see all 12)

About this table Species with no ortholog for P2RX5

ENSEMBL Gene Tree for P2RX5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for P2RX5 gene

P2RX1² P2RX4² P2RX6² P2RX7²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/231 NCBI SNPs in P2RX5 are shown (see all 231 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 71)

AB	SNP ID	Valid	Chr 17 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1063497^1,2	A,C,F,H	3523895(-)	`CTTACG/ATTCAG`	2	--	ut3¹ ese³		13		MN EU EA WA NA	1174
	rs160590^1,2	C,F,H,O	3547057(-)	`CGCGCA/GTTAGT`	3	--	ng3¹		4		EU EA WA	418
	rs222758^1,2	A,C,F,H	3523473(+)	`AGCTGC/TGGCAC`	2	--	ut3¹ ese³		11		EA NA MN EU WA	722
--	rs184343^1,2	A,C	3548100(-)	`CTGTTT/GAAAAA`	3	--	ng3¹ trp³		1		MN	184
	rs1162461^1,2	A,C	3547391(-)	`CCCCCC/GGGAGG`	3	--	ng3¹		0	--	--	--	--
--	rs2134633^1,2	C,F	3548244(+)	`CCACCA/G/TAGTGA`	3	--	ng3¹		1		EA	1498
	rs8066216^1,2	C	3546411(+)	`ACCGCC/GCTGTG`	3	--	ng3¹		0	--	--	--	--
	rs3760477^1,2	F	3548198(-)	`CAGGGG/TGCTGA`	3	--	ng3¹		1		EA	1466
	rs149245^1,2	A,C,F,H	3526401(-)	`GCCGAG/AAACTC`	2	--	int¹		12		MN NA EU EA WA	1154
	rs11655312^1,2	A,C,F,H	3545274(+)	`TTGCCT/CCTTTG`	3	--	int¹		1		EU	120

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HapMap Linkage Disequilibrium images for P2RX5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 602836

1 Novoseek disease relationship for P2RX5 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tumors	0.00	1	12880424 (1)

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Human Gene Mutation Database: P2RX5

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/40 PubMed articles for P2RX5 gene (see all 40 ):

Primary structure and expression of a naturally truncated human P2X ATP receptor subunit from brain and immune system. (PubMed id 9414125)^{2, 3, 4} Le K.-T.... Seguela P. (1997)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion. (PubMed id 10673275)^{3, 4} Touchman J.W....Green E.D. (2000)
Purinoceptor expression on keratinocytes reflects their function on the epidermis during chronic venous insufficiency. (PubMed id 16967306)^{1, 3} Metcalfe M.J....Burnstock G. (2006)
Expression of purinergic receptors in non-melanoma skin cancers and their functional roles in A431 cells. (PubMed id 12880424)^{1, 3} Greig A.V....Burnstock G. (2003)
Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes. (PubMed id 12787128)^{1, 3} Greig A.V....Burnstock G. (2003)
Molecular physiology of P2X receptors. (PubMed id 12270951)^{1, 3} North R.A. (2002)
Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross- validation of MS/MS and MS/MS/MS Spectra. (PubMed id 17924679)⁴ Yu L.-R.... Veenstra T.D. (2007)
Go it alone no more--P2X7 joins the society of heteromeric ATP-gated receptor channels. (PubMed id 17895406)³ Dubyak G.R. (2007)
P2X5 subunit assembly requires scaffolding by the second transmembrane domain and a conserved aspartate. (PubMed id 17001079)³ Duckwitz W....Schmalzing G. (2006)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 5026	HGNC: 8536	AceView: P2RX5	Ensembl:ENSG00000083454	euGenes: HUgn5026
ECgene: P2RX5	H-InvDB: P2RX5

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
Wikipedia	http://en.wikipedia.org/wiki/P2X_receptor

Licensable Technologies for P2RX5
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for P2RX5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for P2RX5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for P2RX5		Antibodies for P2RX5
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for P2RX5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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	Custom Service for Rabbit Pab from Full-length Protein

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	Antibodies (P2X5b, P2X5)

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Tocris compounds for P2RX5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for P2RX5

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P2RX5 Gene

protein-coding GIFtS: 59

Aliases &
Descriptions
for P2RX5

Summaries
for P2RX5

Genomic Location
for P2RX5

Proteins
for P2RX5

Protein Domains/
Families
for P2RX5

Gene Function
for P2RX5

Pathways & Interactions
for P2RX5

Drugs & Compounds
for P2RX5

Transcripts
for P2RX5

Expression
for P2RX5

Orthologs
for P2RX5

Paralogs
for P2RX5

SNPs/Variants
for P2RX5

Disorders & Mutations
for P2RX5

Medical News
for P2RX5

Publications
for P2RX5

Search for P2RX5

Genome Databases showing P2RX5

Other Databases showing P2RX5

Specialized Databases showing P2RX5

Licensable Technologies
for P2RX5

Services
for P2RX5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

P2RX5 Gene

protein-coding GIFtS: 59

Aliases & Descriptionsfor P2RX5

Summariesfor P2RX5

Genomic Locationfor P2RX5

Proteinsfor P2RX5

Protein Domains/Familiesfor P2RX5

Gene Functionfor P2RX5

Pathways & Interactionsfor P2RX5

Drugs & Compoundsfor P2RX5

Transcriptsfor P2RX5

Expression for P2RX5

Orthologsfor P2RX5

Paralogsfor P2RX5

SNPs/Variantsfor P2RX5

Disorders & Mutationsfor P2RX5

Medical Newsfor P2RX5

Publicationsfor P2RX5

Search for P2RX5

Genome Databases showing P2RX5

Other Databases showing P2RX5

Specialized Databases showing P2RX5

Licensable Technologiesfor P2RX5

Servicesfor P2RX5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for P2RX5

Summaries
for P2RX5

Genomic Location
for P2RX5

Proteins
for P2RX5

Protein Domains/
Families
for P2RX5

Gene Function
for P2RX5

Pathways & Interactions
for P2RX5

Drugs & Compounds
for P2RX5

Transcripts
for P2RX5

Expression
for P2RX5

Orthologs
for P2RX5

Paralogs
for P2RX5

SNPs/Variants
for P2RX5

Disorders & Mutations
for P2RX5

Medical News
for P2RX5

Publications
for P2RX5

Licensable Technologies
for P2RX5

Services
for P2RX5