Aliases for P2RX5 Gene
External Ids for P2RX5 Gene
Previous GeneCards Identifiers for P2RX5 Gene
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream gene, TAX1BP3 (Tax1 binding protein 3). [provided by RefSeq, Mar 2011]
GeneCards Summary for P2RX5 Gene
P2RX5 (Purinergic Receptor P2X 5) is a Protein Coding gene. Diseases associated with P2RX5 include cystinosis and chronic venous insufficiency. Among its related pathways are Platelet activation, signaling and aggregation and CREB Pathway. GO annotations related to this gene include transmembrane signaling receptor activity and purinergic nucleotide receptor activity. An important paralog of this gene is P2RX1.
UniProtKB/Swiss-Prot for P2RX5 Gene
Receptor for ATP that acts as a ligand-gated ion channel.
P2X receptors are members of the ligand-gated ion channel family that open in response to extracellular ATP. Each receptor is made up of a trimer of subunits (P2X1-7) all of which share the common structure of two transmembrane domains.