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Aliases for OXNAD1 Gene

Aliases for OXNAD1 Gene

  • Oxidoreductase NAD Binding Domain Containing 1 2 3
  • Oxidoreductase NAD-Binding Domain Containing 1 2 5
  • EC 1.-.-.- 4

External Ids for OXNAD1 Gene

Previous GeneCards Identifiers for OXNAD1 Gene

  • GC03P016282

Summaries for OXNAD1 Gene

GeneCards Summary for OXNAD1 Gene

OXNAD1 (Oxidoreductase NAD Binding Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include oxidoreductase activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OXNAD1 Gene

Genomics for OXNAD1 Gene

Regulatory Elements for OXNAD1 Gene

Enhancers for OXNAD1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OXNAD1 on UCSC Golden Path with GeneCards custom track

Promoters for OXNAD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around OXNAD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OXNAD1 Gene

16,265,160 bp from pter
16,386,979 bp from pter
121,820 bases
Plus strand

Genomic View for OXNAD1 Gene

Genes around OXNAD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OXNAD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OXNAD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OXNAD1 Gene

Proteins for OXNAD1 Gene

  • Protein details for OXNAD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Oxidoreductase NAD-binding domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q2HYC7
    • Q59FA4

    Protein attributes for OXNAD1 Gene

    312 amino acids
    Molecular mass:
    34854 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OXNAD1 Gene

Proteomics data for OXNAD1 Gene at MOPED

Post-translational modifications for OXNAD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OXNAD1 Gene

No data available for DME Specific Peptides for OXNAD1 Gene

Domains & Families for OXNAD1 Gene

Suggested Antigen Peptide Sequences for OXNAD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 FAD-binding FR-type domain.
  • Contains 1 FAD-binding FR-type domain.
genes like me logo Genes that share domains with OXNAD1: view

No data available for Gene Families for OXNAD1 Gene

Function for OXNAD1 Gene

Enzyme Numbers (IUBMB) for OXNAD1 Gene

Phenotypes for OXNAD1 Gene

GenomeRNAi human phenotypes for OXNAD1:
genes like me logo Genes that share phenotypes with OXNAD1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for OXNAD1

miRNA for OXNAD1 Gene

No data available for Molecular function , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OXNAD1 Gene

Localization for OXNAD1 Gene

Subcellular locations from

Jensen Localization Image for OXNAD1 Gene COMPARTMENTS Subcellular localization image for OXNAD1 gene
Compartment Confidence
mitochondrion 3
extracellular 2
cytosol 1
endoplasmic reticulum 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for OXNAD1 Gene

Pathways & Interactions for OXNAD1 Gene

SuperPathways for OXNAD1 Gene

No Data Available

Interacting Proteins for OXNAD1 Gene

Gene Ontology (GO) - Biological Process for OXNAD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with OXNAD1: view

No data available for Pathways by source and SIGNOR curated interactions for OXNAD1 Gene

Drugs & Compounds for OXNAD1 Gene

(1) Drugs for OXNAD1 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
FAD Approved Pharma 0
genes like me logo Genes that share compounds with OXNAD1: view

Transcripts for OXNAD1 Gene

Unigene Clusters for OXNAD1 Gene

Oxidoreductase NAD-binding domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OXNAD1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c · 3d ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
SP1: - - -
SP2: - -
SP4: -
SP5: -

Relevant External Links for OXNAD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OXNAD1 Gene

mRNA expression in normal human tissues for OXNAD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for OXNAD1 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (64.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for OXNAD1 Gene

SOURCE GeneReport for Unigene cluster for OXNAD1 Gene Hs.655449

genes like me logo Genes that share expression patterns with OXNAD1: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OXNAD1 Gene

Orthologs for OXNAD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OXNAD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OXNAD1 35
  • 82.74 (n)
  • 82.74 (a)
  • 82 (a)
(Canis familiaris)
Mammalia OXNAD1 35
  • 90.49 (n)
  • 90.71 (a)
  • 91 (a)
(Mus musculus)
Mammalia Oxnad1 35
  • 84.31 (n)
  • 80.72 (a)
Oxnad1 16
Oxnad1 36
  • 79 (a)
(Pan troglodytes)
Mammalia OXNAD1 35
  • 99.47 (n)
  • 99.36 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Oxnad1 35
  • 83.17 (n)
  • 81.88 (a)
(Monodelphis domestica)
Mammalia OXNAD1 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia OXNAD1 36
  • 66 (a)
(Gallus gallus)
Aves OXNAD1 35
  • 68.15 (n)
  • 59.26 (a)
  • 57 (a)
(Anolis carolinensis)
Reptilia OXNAD1 36
  • 58 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia oxnad1 35
  • 64.13 (n)
  • 59.6 (a)
Str.14109 35
African clawed frog
(Xenopus laevis)
Amphibia MGC68903 35
(Danio rerio)
Actinopterygii oxnad1 35
  • 60.72 (n)
  • 57.62 (a)
oxnad1 36
  • 52 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.129 36
  • 38 (a)
Species with no ortholog for OXNAD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OXNAD1 Gene

Gene Tree for OXNAD1 (if available)
Gene Tree for OXNAD1 (if available)

Paralogs for OXNAD1 Gene

No data available for Paralogs for OXNAD1 Gene

Variants for OXNAD1 Gene

Sequence variations from dbSNP and Humsavar for OXNAD1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs17042066 - 16,271,715(+) CCTTC(A/G)ACGGG nc-transcript-variant, reference, missense, utr-variant-5-prime
rs842274 - 16,286,348(-) TGCTG(A/C)CACAA nc-transcript-variant, reference, missense
rs6777976 - 16,286,402(+) GCCTC(C/T)GCTTG nc-transcript-variant, reference, missense
rs2280138 -- 16,303,000(+) AGTGT(A/C)CATAC intron-variant
rs2292616 -- 16,301,487(+) GGCAT(C/T)GGGAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OXNAD1 Gene

Variant ID Type Subtype PubMed ID
nsv876585 CNV Gain 21882294

Variation tolerance for OXNAD1 Gene

Residual Variation Intolerance Score: 92.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 14.16; 96.17% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OXNAD1 Gene

Disorders for OXNAD1 Gene

Relevant External Links for OXNAD1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OXNAD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OXNAD1 Gene

Publications for OXNAD1 Gene

  1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3

Products for OXNAD1 Gene

Sources for OXNAD1 Gene