Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OXLD1 Gene

Subcategory (RNA class) for OXLD1 Gene

lncRNA

Aliases for OXLD1 Gene

  • Oxidoreductase Like Domain Containing 1 2 3 5
  • C17orf90 3 4
  • Oxidoreductase-Like Domain-Containing Protein 1 3
  • Oxidoreductase-Like Domain Containing 1 2
  • Chromosome 17 Open Reading Frame 90 2

External Ids for OXLD1 Gene

ORGUL Members for OXLD1 Gene

Previous HGNC Symbols for OXLD1 Gene

  • C17orf90

Previous GeneCards Identifiers for OXLD1 Gene

  • GC17M079633

Summaries for OXLD1 Gene

GeneCards Summary for OXLD1 Gene

OXLD1 (Oxidoreductase Like Domain Containing 1) is a Protein Coding gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OXLD1 Gene

Genomics for OXLD1 Gene

Regulatory Elements for OXLD1 Gene

Enhancers for OXLD1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G081558 1.4 Ensembl ENCODE dbSUPER 19.9 +102.3 102275 11.1 PKNOX1 NFIB ZSCAN4 SIN3A FEZF1 RAD21 ZNF366 FOS RELB EGR2 NPLOC4 TSPAN10 ARL16 OXLD1 FSCN2 ENSG00000229848 PDE6G CCDC137 GCGR MCRIP1
GH17G081596 1.3 Ensembl ENCODE dbSUPER 12 +67.2 67178 5.4 HDGF SIN3A RAD21 ZNF143 RELB ETV6 ZNF391 IKZF2 CREM ZNF654 TSPAN10 NPLOC4 ARL16 FAAP100 PDE6G CCDC137 OXLD1 TMEM105 GC17M081598 GC17M081601
GH17G082095 2.1 FANTOM5 Ensembl ENCODE dbSUPER 4.9 -435.2 -435173 13.5 MLX CREB3L1 AGO1 ZFP64 DMAP1 FEZF1 YY1 SLC30A9 ZNF143 ZNF263 CCDC57 ARL16 DCXR TSPAN10 ENSG00000262049 RFNG DUS1L HEXDC GCGR OXLD1
GH17G080855 2 FANTOM5 Ensembl ENCODE dbSUPER 4.9 +807.6 807605 7.8 FOXA2 CREB3L1 MLX ARNT WRNIP1 SIN3A ARID4B DMAP1 ZNF766 FOS OXLD1 LOC105371921 LOC101928855
GH17G081583 1 dbSUPER 7.5 +82.9 82903 0.7 FOXA2 FEZF1 ZNF2 ZNF121 KLF7 ZNF263 SP3 SP5 TSHZ1 ZNF488 ARL16 TSPAN10 HGS OXLD1 PIR48383 ENSG00000207021 GC17M081598
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OXLD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OXLD1 Gene

Chromosome:
17
Start:
81,665,036 bp from pter
End:
81,666,637 bp from pter
Size:
1,602 bases
Orientation:
Minus strand

Genomic View for OXLD1 Gene

Genes around OXLD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OXLD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OXLD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OXLD1 Gene

Proteins for OXLD1 Gene

  • Protein details for OXLD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5BKU9-OXLD1_HUMAN
    Recommended name:
    Oxidoreductase-like domain-containing protein 1
    Protein Accession:
    Q5BKU9
    Secondary Accessions:
    • A6ND24

    Protein attributes for OXLD1 Gene

    Size:
    147 amino acids
    Molecular mass:
    15855 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OXLD1 Gene

Post-translational modifications for OXLD1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for OXLD1 Gene

Domains & Families for OXLD1 Gene

Protein Domains for OXLD1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OXLD1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for OXLD1 Gene

Function for OXLD1 Gene

Phenotypes for OXLD1 Gene

genes like me logo Genes that share phenotypes with OXLD1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OXLD1 Gene

Localization for OXLD1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OXLD1 gene
Compartment Confidence
mitochondrion 4
nucleus 2
cytosol 2
extracellular 1

Gene Ontology (GO) - Cellular Components for OXLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with OXLD1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for OXLD1 Gene

Pathways & Interactions for OXLD1 Gene

SuperPathways for OXLD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for OXLD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for OXLD1 Gene

Drugs & Compounds for OXLD1 Gene

No Compound Related Data Available

Transcripts for OXLD1 Gene

mRNA/cDNA for OXLD1 Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OXLD1 Gene

Oxidoreductase-like domain containing 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for OXLD1 Gene

No ASD Table

Relevant External Links for OXLD1 Gene

GeneLoc Exon Structure for
OXLD1
ECgene alternative splicing isoforms for
OXLD1

Expression for OXLD1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OXLD1 Gene

Protein differential expression in normal tissues from HIPED for OXLD1 Gene

This gene is overexpressed in Lung (19.2), Heart (10.9), Frontal cortex (7.5), and Ovary (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for OXLD1 Gene



NURSA nuclear receptor signaling pathways regulating expression of OXLD1 Gene:

OXLD1

SOURCE GeneReport for Unigene cluster for OXLD1 Gene:

Hs.405942
genes like me logo Genes that share expression patterns with OXLD1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OXLD1 Gene

Orthologs for OXLD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OXLD1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OXLD1 34 35
  • 99.77 (n)
dog
(Canis familiaris)
Mammalia OXLD1 34 35
  • 78.46 (n)
cow
(Bos Taurus)
Mammalia OXLD1 34 35
  • 78.01 (n)
mouse
(Mus musculus)
Mammalia Oxld1 34 16 35
  • 72.26 (n)
lizard
(Anolis carolinensis)
Reptilia OXLD1 35
  • 59 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii oxld1 35
  • 34 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG5500 35
  • 27 (a)
OneToOne
Species where no ortholog for OXLD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OXLD1 Gene

ENSEMBL:
Gene Tree for OXLD1 (if available)
TreeFam:
Gene Tree for OXLD1 (if available)

Paralogs for OXLD1 Gene

No data available for Paralogs for OXLD1 Gene

Variants for OXLD1 Gene

Sequence variations from dbSNP and Humsavar for OXLD1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000030742 -- 81,667,578(+) CATCT(A/C)GGCCT intron-variant, upstream-variant-2KB
rs1001800344 -- 81,666,015(+) ACCAC(C/T)CTTTA intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs1003013854 -- 81,666,803(+) CCAGG(C/G/T)TGCAG upstream-variant-2KB, reference, missense
rs1003191696 -- 81,666,400(+) CTCCC(A/G)GCTCC intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs1003265369 -- 81,666,099(+) CTTCC(-/G)TCGCT intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for OXLD1 Gene

Variant ID Type Subtype PubMed ID
esv26223 CNV gain+loss 19812545
nsv428351 CNV gain 18775914
nsv470620 CNV loss 18288195
nsv828128 CNV loss 20364138
nsv952390 CNV deletion 24416366

Variation tolerance for OXLD1 Gene

Residual Variation Intolerance Score: 89.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.13; 22.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OXLD1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OXLD1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OXLD1 Gene

Disorders for OXLD1 Gene

Relevant External Links for OXLD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OXLD1

No disorders were found for OXLD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OXLD1 Gene

Publications for OXLD1 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  2. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3 64
  3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OXLD1 Gene

Sources for OXLD1 Gene

Content
Loading form....