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Aliases for OXLD1 Gene

Subcategory (RNA class) for OXLD1 Gene


Aliases for OXLD1 Gene

  • Oxidoreductase Like Domain Containing 1 2 3 5
  • C17orf90 3 4
  • Oxidoreductase-Like Domain-Containing Protein 1 3
  • Oxidoreductase-Like Domain Containing 1 2
  • Chromosome 17 Open Reading Frame 90 2

External Ids for OXLD1 Gene

ORGUL Members for OXLD1 Gene

Previous HGNC Symbols for OXLD1 Gene

  • C17orf90

Previous GeneCards Identifiers for OXLD1 Gene

  • GC17M079633

Summaries for OXLD1 Gene

GeneCards Summary for OXLD1 Gene

OXLD1 (Oxidoreductase Like Domain Containing 1) is a Protein Coding gene, and is affiliated with the lncRNA class.

Additional gene information for OXLD1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OXLD1 Gene

Genomics for OXLD1 Gene

Regulatory Elements for OXLD1 Gene

Enhancers for OXLD1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H080831 2 FANTOM5 Ensembl ENCODE dbSUPER 14.4 +832.9 832931 4.6 HDGF PKNOX1 ATF1 SIN3A ZNF2 YY1 GLIS2 ZNF207 FOS ATF7 OXLD1 HGS CCDC137 CEP131 LOC105371925 TEPSIN LOC101928855 LOC105371921
GH17H081558 1.4 Ensembl ENCODE dbSUPER 19.9 +102.3 102275 11.1 PKNOX1 FOXA2 NFIB ZSCAN4 SIN3A FEZF1 BATF RAD21 ZNF366 FOS NPLOC4 TSPAN10 ARL16 OXLD1 ENSG00000229848 FSCN2 ENSG00000262877 PDE6G CCDC137 GCGR
GH17H082271 1.4 ENCODE dbSUPER 14.4 -606.4 -606435 3.5 HDGF PKNOX1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 ALYREF OGFOD3 OXLD1 ENSG00000263321 HGS NPLOC4 LOC105371942 ENSG00000260011 ENSG00000262877 CCDC137
GH17H081424 1.2 ENCODE dbSUPER 14.5 +241.9 241862 0.2 HDGF YBX1 PLRG1 ZBTB7B ZNF155 YY2 ZNF114 ZIK1 ZNF488 ZNF662 OGFOD3 FAAP100 CEP131 ENSG00000262877 TEPSIN ENSG00000265678 HEXDC HGS ENSG00000260563 ENSG00000260369
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OXLD1 on UCSC Golden Path with GeneCards custom track

Promoters for OXLD1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000099460 -163 1601 PKNOX1 ARNT ARID4B SIN3A DMAP1 YY1 ZNF766 ZNF143 ZNF207 FOS

Genomic Locations for OXLD1 Gene

Genomic Locations for OXLD1 Gene
1,602 bases
Minus strand

Genomic View for OXLD1 Gene

Genes around OXLD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OXLD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OXLD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OXLD1 Gene

Proteins for OXLD1 Gene

  • Protein details for OXLD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Oxidoreductase-like domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • A6ND24

    Protein attributes for OXLD1 Gene

    147 amino acids
    Molecular mass:
    15855 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OXLD1 Gene

Post-translational modifications for OXLD1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for OXLD1 Gene

Domains & Families for OXLD1 Gene

Gene Families for OXLD1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for OXLD1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OXLD1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for OXLD1 Gene

Function for OXLD1 Gene

Phenotypes From GWAS Catalog for OXLD1 Gene

Phenotypes for OXLD1 Gene

genes like me logo Genes that share phenotypes with OXLD1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OXLD1 Gene

Localization for OXLD1 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OXLD1 gene
Compartment Confidence
mitochondrion 4
nucleus 2
cytosol 2
extracellular 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Vesicles (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for OXLD1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with OXLD1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for OXLD1 Gene

Pathways & Interactions for OXLD1 Gene

SuperPathways for OXLD1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for OXLD1 Gene


No data available for Pathways by source and SIGNOR curated interactions for OXLD1 Gene

Drugs & Compounds for OXLD1 Gene

No Compound Related Data Available

Transcripts for OXLD1 Gene

mRNA/cDNA for OXLD1 Gene

(4) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OXLD1 Gene

Oxidoreductase-like domain containing 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for OXLD1 Gene

No ASD Table

Relevant External Links for OXLD1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OXLD1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OXLD1 Gene

Protein differential expression in normal tissues from HIPED for OXLD1 Gene

This gene is overexpressed in Lung (19.2), Heart (10.9), Frontal cortex (7.5), and Ovary (6.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for OXLD1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OXLD1 Gene:


SOURCE GeneReport for Unigene cluster for OXLD1 Gene:

genes like me logo Genes that share expression patterns with OXLD1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OXLD1 Gene

Orthologs for OXLD1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OXLD1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia OXLD1 33 34
  • 99.77 (n)
(Canis familiaris)
Mammalia OXLD1 33 34
  • 78.46 (n)
(Bos Taurus)
Mammalia OXLD1 33 34
  • 78.01 (n)
(Mus musculus)
Mammalia Oxld1 33 16 34
  • 72.26 (n)
(Anolis carolinensis)
Reptilia OXLD1 34
  • 59 (a)
(Danio rerio)
Actinopterygii oxld1 34
  • 34 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG5500 34
  • 27 (a)
Species where no ortholog for OXLD1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OXLD1 Gene

Gene Tree for OXLD1 (if available)
Gene Tree for OXLD1 (if available)

Paralogs for OXLD1 Gene

No data available for Paralogs for OXLD1 Gene

Variants for OXLD1 Gene

Sequence variations from dbSNP and Humsavar for OXLD1 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000030742 -- 81,667,578(+) CATCT(A/C)GGCCT intron-variant, upstream-variant-2KB
rs1001800344 -- 81,666,015(+) ACCAC(C/T)CTTTA intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs1003013854 -- 81,666,803(+) CCAGG(C/G/T)TGCAG upstream-variant-2KB, reference, missense
rs1003191696 -- 81,666,400(+) CTCCC(A/G)GCTCC intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs1003265369 -- 81,666,099(+) CTTCC(-/G)TCGCT intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for OXLD1 Gene

Variant ID Type Subtype PubMed ID
nsv952390 CNV deletion 24416366
nsv828128 CNV loss 20364138
nsv470620 CNV loss 18288195
nsv428351 CNV gain 18775914
esv26223 CNV gain+loss 19812545

Variation tolerance for OXLD1 Gene

Residual Variation Intolerance Score: 89.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.13; 22.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OXLD1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OXLD1 Gene

Disorders for OXLD1 Gene

Relevant External Links for OXLD1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OXLD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OXLD1 Gene

Publications for OXLD1 Gene

  1. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 60
  3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 60
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60

Products for OXLD1 Gene

Sources for OXLD1 Gene

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