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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OXER1 Gene

protein-coding   GIFtS: 54
GCID: GC02M042989

Oxoeicosanoid (OXE) Receptor 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Oxoeicosanoid (OXE) Receptor 11 2     G-Protein Coupled Receptor 1702 3
5-Oxo-ETE Acid G-Protein-Coupled Receptor 11 2     G-Protein Coupled Receptor R5272 3
5-Oxo-ETE G-Protein Coupled Receptor2 3     G-Protein Coupled Receptor TG10192 3
GPR1702 3     GPCR2
TG10192 3     Oxoeicosanoid Receptor 12

External Ids:    HGNC: 248841   Entrez Gene: 1651402   Ensembl: ENSG000001628817   UniProtKB: Q8TDS53   

Export aliases for OXER1 gene to outside databases

Previous GC identifers: GC02M042930 GC02M042901 GC02M042843 GC02M042723


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for OXER1 Gene: 
OXER1 (oxoeicosanoid (OXE) receptor 1) is a protein-coding gene. Diseases associated with OXER1 include allergic encephalomyelitis, and diabetes insipidus, and among its related super-pathways are Signaling by GPCR and GPCR ligand binding. GO annotations related to this gene include 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding and G-protein coupled receptor activity. An important paralog of this gene is HCAR1.

UniProtKB/Swiss-Prot: OXER1_HUMAN, Q8TDS5
Function: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic
acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems
to be coupled to the G(i)/G(o), families of heteromeric G proteins

summary for OXER1 Gene:
Leukotriene and related receptors are activated by the endogenous ligands leukotriene (LT) B4, LTC4, LTD4,
LTE4 and 12-HETE. Leukotrienes are lipid mediators synthesized from arachidonic acid by lipoxygenase
enzymes. They act on peroxisome-proliferating receptors (PPARs) as well as the G-protein-coupled leukotriene
receptors, and are important in inflammatory signaling pathways. Leukotriene and related receptors are high
affinity stereoselective receptors that have a wide biological distribution. The oxoeicosanoid receptor
(OXE) is expressed in high concentrations on eosinophils, neutrophils and monocytes and is involved in
chemotaxis and intracellular calcium mobilization.

Gene Wiki entry for OXER1 (Oxoeicosanoid receptor 1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.2  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OXER1 gene promoter:
         ER-alpha   p53   Sp1   XBP-1   Nkx2-5   FOXL1   PPAR-gamma1   c-Myb   SEF-1 (1)   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for OXER1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OXER1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p21   Ensembl cytogenetic band:  2p21   HGNC cytogenetic band: 2p22.1

OXER1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OXER1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M042989:  view genomic region     (about GC identifiers)

Start:
42,989,639 bp from pter      End:
42,991,401 bp from pter
Size:
1,763 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OXER1_HUMAN, Q8TDS5 (See protein sequence)
Recommended Name: Oxoeicosanoid receptor 1  
Size: 423 amino acids; 45811 Da
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAO17739.1; Type=Erroneous initiation; Sequence=BAC05878.1; Type=Erroneous initiation;
Secondary accessions: Q86WP7 Q8NGW4

Explore the universe of human proteins at neXtProt for OXER1: NX_Q8TDS5

Explore proteomics data for OXER1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TDS5

  • OXER1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OXER1 Protein Expression
    REFSEQ proteins: NP_683765.1  
    ENSEMBL proteins: 
     ENSP00000367930  
    Reactome Protein details: Q8TDS5
    Human Recombinant Protein Products for OXER1: 
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    Novus Biologicals OXER1 Proteins
    Novus Biologicals OXER1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OXER1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    OXER1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for OXER1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    LTNR: GPCR / Class A : Leukotriene receptors

    IUPHAR Guide to PHARMACOLOGY protein family classification: OXE receptor 
    Leukotriene receptors

    2 InterPro protein domains:
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry Q8TDS5

    ProtoNet protein and cluster: Q8TDS5

    UniProtKB/Swiss-Prot: OXER1_HUMAN, Q8TDS5
    Similarity: Belongs to the G-protein coupled receptor 1 family


    OXER1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OXER1_HUMAN, Q8TDS5
    Function: Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic
    acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems
    to be coupled to the G(i)/G(o), families of heteromeric G proteins

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity NAS12065583
    GO:00506465-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding NAS12065583
    GO:00506475-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding NAS12065583
    GO:00506485(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding NAS12065583
         
    OXER1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OXER1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OXER1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OXER1 
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    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate OXER1:
    hsa-miR-214*
    SwitchGear 3'UTR luciferase reporter plasmidOXER1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for OXER1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90
    2Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)0.71
    G alpha (i) signalling events0.46
    GPCR ligand binding0.71
    3Prostanoid ligand receptors
    Eicosanoid ligand-binding receptors0.60

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/7        Reactome Pathways for OXER1 (see all 7)
        GPCR downstream signaling
    Eicosanoid ligand-binding receptors
    Signal Transduction
    Signaling by GPCR
    G alpha (i) signalling events



    OXER1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OXER1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/143 Interacting proteins for OXER1 (ENSP000003679304) via UniProtKB, MINT, STRING, and/or I2D (see all 143)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCR3ENSP000003500034STRING: ENSP00000350003
    CXCR1ENSP000002956834STRING: ENSP00000295683
    FPR3ENSP000003418214STRING: ENSP00000341821
    GPR18ENSP000003434284STRING: ENSP00000343428
    GPR55ENSP000003758934STRING: ENSP00000375893
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway NAS12065583
    GO:0030817regulation of cAMP biosynthetic process IDA12065583

    OXER1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    OXER1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Enzo Life Sciences drugs & compounds for OXER1

    Compounds for OXER1 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    17-ODYALTB-omega-Hydroxylase inhibitor[34450-18-5]
    MK 571Potent CysLT1 (LTD4) inverse agonist. Also MRP inhibitor[115104-28-4]
    Cinalukast Potent, selective CysLT1 (LTD4) antagonist; orally active [128312-51-6]
    LY 255283 Selective, competitive BLT2 receptor antagonist [117690-79-6]
    Leukotriene B4BLT1/BLT2 receptor agonist and potent chemotactic factor[71160-24-2]

    1 HMDB Compound for OXER1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Arachidonic acid5,8,11,14-Eicosatetraenoic acid (see all 16)506-32-1--

    10/11 IUPHAR Ligands for OXER1 (OXE receptor) (see all 11)    About this table 
    LigandTypeActionAffinityPubmed IDs
    5-oxo-ETE
    AgonistFull agonist8.3 - 8.57797484 9829988 18292294 1326548 19450703
    [3H]5-oxo-ETE
    AgonistAgonist8.49829988
    5-oxo-C20:3
    AgonistFull agonist818292294
    5-oxo-ODE
    AgonistFull agonist818287092
    5-oxo-15-HETE
    AgonistFull agonist7.78387490 7797484 8598482 7803484
    5S-HETE
    AgonistFull agonist6.5 - 7.27803484 8387490 16039985
    5S-HPETE
    AgonistFull agonist716039985
    5-oxo-20-HETE
    AgonistFull agonist6.58598482
    5-(6-chloro-2-hexyl-1H-indol-1-yl)-5-oxo-valeric acid
    AntagonistAntagonist6.423581530
    5-oxo-12-HETE
    AntagonistAntagonist6.39920859

    9 Novoseek inferred chemical compound relationships for OXER1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-oxoete 79.1 4 12065583 (2), 16567419 (1)
    arachidonic acid 28 2 12065583 (1), 16567419 (1)
    bacteriorhodopsin 18.3 7 8319802 (4)
    tyrosine 12.8 5 16842754 (1), 19305425 (1), 7651538 (1), 14647423 (1)
    amine 1.52 2 17826096 (1), 11056049 (1)
    lipid 0 1 19442546 (1)
    calcium 0 2 16125366 (1)
    serine 0 2 16878972 (1), 19008357 (1)
    cysteine 0 1 15674329 (1)

    Search CenterWatch for drugs/clinical trials and news about OXER1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OXER1 gene: 
    NM_148962.4  

    Unigene Cluster for OXER1:

    Oxoeicosanoid (OXE) receptor 1
    Hs.168439  [show with all ESTs]
    Unigene Representative Sequence: BC063549
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000378661(uc002rss.3)
    miRNA
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    Inhib. RNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OXER1
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    Additional mRNA sequence: 

    AB083055.2 AY158687.1 BC063549.1 

    1 DOTS entry:

    DT.305686 

    15 AceView cDNA sequences:

    NM_148962 AB083055 BC063549 AI478304 BI906118 AW207726 AK123057 AY158687 
    BG742555 AW263816 CO245334 AA534545 T72122 T71978 BG959459 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OXER1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTCCCTGGC
    OXER1 Expression
    About this image


    See OXER1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OXER1

    SOURCE GeneReport for Unigene cluster: Hs.168439

    UniProtKB/Swiss-Prot: OXER1_HUMAN, Q8TDS5
    Tissue specificity: Expressed in various tissues except brain. Expression is more intense in liver, kidney,
    peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and
    lung macrophages

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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OXER1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OXER1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for OXER1 gene from 2/5 species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia OXER11 oxoeicosanoid (OXE) receptor 1 82.8(n)
    77.45(a)
      481349  XM_538470.3  XP_538470.3 
    zebrafish
    (Danio rerio)
    Actinopterygii hcar1-36
    GPR81-46
    Uncharacterized protein
    39(a)
    31(a)
    1 ↔ many
    1 ↔ many
    13(8353414-8359589)
    12(26820810-26821748)


    ENSEMBL Gene Tree for OXER1 (if available)
    TreeFam Gene Tree for OXER1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OXER1 gene
    HCAR12  GPR312  HCAR32  GPR202  HCAR22  
    4 SIMAP similar genes for OXER1 using alignment to 2 protein entries:     OXER1_HUMAN (see all proteins):
    HCAR3    GPR31    HCAR2    HCAR1

    OXER1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/195 SNPs in OXER1 are shown (see all 195)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs49536531,2
    C,F,A,H--42989159(+) TCACCT/CGCTCA 1 -- int118Minor allele frequency- C:0.27NS EA NA WA CSA 795
    rs1489549371,2
    --42989235(+) GGACCC/GTTGAT 1 -- int10--------
    rs1907714531,2
    --42989294(+) CCTGAC/TGACTT 1 -- int10--------
    rs1426330541,2
    --42989300(+) GACTTC/TAGTAG 1 -- int10--------
    rs1509802691,2
    C--42989402(+) GTACCC/TGAGGG 1 -- int10--------
    rs22785821,2
    C,F,H--42989444(+) ACCCAG/AGAAAG 1 -- int125Minor allele frequency- A:0.21EA NS NA WA CSA 3676
    rs1409756821,2
    --42989520(+) ATGGGG/TCTGTG 1 -- int10--------
    rs1448847881,2
    --42989570(+) TGGGGC/TGCTCA 1 -- int10--------
    rs1387301541,2
    C--42989582(+) TTTGAC/TGCCTA 1 -- int10--------
    rs1402554711,2
    --42989583(+) TTGACA/GCCTAC 1 -- int10--------

    HapMap Linkage Disequilibrium report for OXER1 (42989639 - 42991401 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for OXER1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv519877CNV Loss19592680
    nsv457152CNV Loss19166990
    nsv817795CNV Gain17921354

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    10 diseases for OXER1:    About MalaCards
    allergic encephalomyelitis    diabetes insipidus    encephalomyelitis    attention deficit hyperactivity disorder
    obesity    asthma    prostate cancer    prostatitis
    breast cancer    neuronitis


    OXER1 for disorders           About GeneDecksing

    5 Novoseek inferred disease relationships for OXER1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    diabetes insipidus nephrogenic 35.1 1 15556674 (1)
    retinitis pigmentosa 9.29 1 15556674 (1)
    tumors 1.55 3 15674329 (1), 19552766 (1)
    inflammation 0 1 12667650 (1)
    cancer 0 1 14647423 (1)

    Genetic Association Database (GAD): OXER1

    Export disorders for OXER1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OXER1 gene, integrated from 9 sources (see all 139):
    (articles sorted by number of sources associating them with OXER1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel human eicosanoid receptor coupled to G(i/o). (PubMed id 12065583)1, 2, 3, 9 Hosoi T.... Ohnuki T. (2002)
    2. Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations. (PubMed id 18821565)1, 4 Lasky-Su J....Faraone S.V. (2008)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. International Union of Pharmacology XLIV. Nomenclature for the oxoeicosanoid receptor. (PubMed id 15001665)1, 3 Brink C....Yokomizo T. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Expression and characterization of a 5-oxo-6E,8Z,11Z,14Z- eicosatetraenoic acid receptor highly expressed on human eosinophils and neutrophils. (PubMed id 12606753)1, 2 Jones C.E.... Finan P. (2003)
    7. Identification of G protein-coupled receptor genes from the human genome sequence. (PubMed id 12044878)1, 2 Takeda S.... Mitaku S. (2002)
    8. OXER1, a G protein-coupled oxoeicosatetraenoid recepto r, mediates the survival-promoting effects of arachidonate 5-lipoxygenase in pro state cancer cells. (PubMed id 23643940)1 Sarveswaran S. and Ghosh J. (2013)
    9. Dissociation of heterotrimeric g proteins in cells. (PubMed id 18577758)1 Lambert N.A. (2008)
    10. Expression of 5-oxoETE receptor in prostate cancer cells: critical role in survival. (PubMed id 16289380)1 Sundaram S. and Ghosh J. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 165140 HGNC: 24884 AceView: OXER1 Ensembl:ENSG00000162881 euGenes: HUgn165140
    ECgene: OXER1 H-InvDB: OXER1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OXER1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OXER1 gene:
    Search GeneIP for patents involving OXER1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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