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OXCT2 Gene

protein-coding   GIFtS: 50
GCID: GC01M040235

3-Oxoacid CoA Transferase 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
3-Oxoacid CoA Transferase 21 2     Succinyl-CoA:3-Ketoacid Coenzyme A Transferase 2, Mitochondrial2
Testis-Specific Succinyl-CoA:3-Oxoacid CoA-Transferase2 3     Succinyl-CoA:3-Ketoacid-Coenzyme A Transferase 2, Mitochondrial2
3-Oxoacid CoA-Transferase 2A2 3     Testis-Specific Succinyl CoA:3-Oxoacid CoA-Transferase2
EC 2.8.3.53 8     SCOT-t3
3-Oxoacid-CoA Transferase 2A2     FLJ00305
SCOTT2     EC 2.8.38

External Ids:    HGNC: 186061   Entrez Gene: 640642   Ensembl: ENSG000001987547   OMIM: 6102895   UniProtKB: Q9BYC23   

Export aliases for OXCT2 gene to outside databases

Previous GC identifers: GC01P039898 GC01M039238 GC01M039698 GC01M039648 GC01M039904 GC01M040007 GC01M038353


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for OXCT2 Gene:
OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2.8.3.5), which catalyzes the reversible
transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilization. See also OXCT1
(MIM 601424).(supplied by OMIM, Mar 2008)

GeneCards Summary for OXCT2 Gene:
OXCT2 (3-oxoacid CoA transferase 2) is a protein-coding gene. GO annotations related to this gene include 3-oxoacid CoA-transferase activity. An important paralog of this gene is OXCT1.

UniProtKB/Swiss-Prot: SCOT2_HUMAN, Q9BYC2
Function: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate.
Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the
carboxylate groups of the enzyme and substrate (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the OXCT2 gene promoter:
         HSF1 (long)   RelA   NF-E2 p45   NF-kappaB   Egr-4   HOXA5   c-Myb   NF-kappaB1   NF-E2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for OXCT2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OXCT2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p34

OXCT2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OXCT2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M040235:  view genomic region     (about GC identifiers)

Start:
40,235,195 bp from pter      End:
40,237,020 bp from pter
Size:
1,826 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SCOT2_HUMAN, Q9BYC2 (See protein sequence)
Recommended Name: Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial precursor  
Size: 517 amino acids; 56140 Da
Subunit: Homodimer (By similarity)
Secondary accessions: B2RBB4 Q5QPK4 Q8NHR1 Q9H1I4

Explore the universe of human proteins at neXtProt for OXCT2: NX_Q9BYC2

Explore proteomics data for OXCT2 at MOPED

Selected DME Specific Peptides for OXCT2 (Q9BYC2) (see all 15)
 GDLANWM  DLINAGK  ERIRAGG  KIMEKCT 


See OXCT2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_071403.1  
ENSEMBL proteins: 
 ENSP00000361914  

OXCT2 Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for OXCT2
OriGene Custom MassSpec
OriGene Custom Protein Services for OXCT2
GenScript Custom Purified and Recombinant Proteins Services for OXCT2
Novus Biologicals OXCT2 Protein
Novus Biologicals OXCT2 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for OXCT2

 
Search eBioscience for Proteins for OXCT2 

OXCT2 Antibody Products:

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Browse R&D Systems for Antibodies
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OriGene Custom Antibody Services for OXCT2
Novus Biologicals OXCT2 Antibodies
Search for Antibodies for OXCT2 at Abcam
Cloud-Clone Corp. Antibodies for OXCT2
Search ThermoFisher Antibodies for OXCT2
LSBio Antibodies in human, mouse, rat for OXCT2

OXCT2 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for OXCT2
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for OXCT2
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for OXCT2
Cloud-Clone Corp. CLIAs for OXCT2
Search eBioscience for ELISAs for OXCT2 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Selected InterPro protein domains (see all 6):
 IPR012791 3-oxoacid_CoA-transf_B
 IPR004163 CoA_transf_BS
 IPR014388 3-oxoacid_CoA-transferase
 IPR012792 3-oxoacid_CoA-transf_A
 IPR004164 CoA_transf_AS

Graphical View of Domain Structure for InterPro Entry Q9BYC2

ProtoNet protein and cluster: Q9BYC2

1 Blocks protein domain: IPB004164 Coenzyme A transferase 2

UniProtKB/Swiss-Prot: SCOT2_HUMAN, Q9BYC2
Similarity: Belongs to the 3-oxoacid CoA-transferase family


Find genes that share domains with OXCT2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: SCOT2_HUMAN, Q9BYC2
Function: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate.
Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the
carboxylate groups of the enzyme and substrate (By similarity)
Catalytic activity: Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA

     Enzyme Numbers (IUBMB): EC 2.8.3.51 2 EC 2.8.32

     Gene Ontology (GO): 2 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:00082603-oxoacid CoA-transferase activity IEA--
GO:0008410CoA-transferase activity ----
     
Find genes that share ontologies with OXCT2           About GenesLikeMe


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OXCT2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for OXCT2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OXCT2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OXCT2

miRNA
Products:
    
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Search for qRT-PCR Assays for microRNAs that regulate OXCT2
SwitchGear 3'UTR luciferase reporter plasmidOXCT2 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for OXCT2
Predesigned siRNA for gene silencing in human, mouse, rat OXCT2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for OXCT2

Clone
Products:
     
OriGene clones in human, mouse for OXCT2 (see all 7)
OriGene ORF clones in mouse, rat for OXCT2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: OXCT2 (NM_022120)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for OXCT2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OXCT2

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for OXCT2
Browse ESI BIO Cell Lines and PureStem Progenitors for OXCT2 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OXCT2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
SCOT2_HUMAN, Q9BYC2: Mitochondrion
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
mitochondrion5

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion IDA11756565
GO:0031514motile cilium IDA11756565

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for OXCT2 About    
See pathways by source

SuperPathContained pathways About
1Butanoate metabolism
Butanoate metabolism
Synthesis and degradation of ketone bodies0.00
2Valine, leucine and isoleucine degradation
Valine, leucine and isoleucine degradation0.31


Find genes that share SuperPaths with OXCT2           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways



3 Kegg Pathways  (Kegg details for OXCT2):
    Synthesis and degradation of ketone bodies
Valine, leucine and isoleucine degradation
Butanoate metabolism

UniProtKB/Swiss-Prot: SCOT2_HUMAN, Q9BYC2
Pathway: Ketone metabolism; succinyl-CoA degradation; acetoacetyl-CoA from succinyl-CoA: step 1/1

    Pathway & Disease-focused RT2 Profiler PCR Arrays including OXCT2: 

          Fatty Acid Metabolism in human mouse rat
          Amino Acid Metabolism I in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for OXCT2

STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

Selected Interacting proteins for OXCT2 (ENSP000003619144) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
InteractantInteraction Details
GeneCardExternal ID(s)
ACAT1ENSP000002658384STRING: ENSP00000265838
ACAT2ENSP000003560154STRING: ENSP00000356015
BDH1ENSP000003509144STRING: ENSP00000350914
HADHENSP000003122884STRING: ENSP00000312288
HMGCLENSP000003636144STRING: ENSP00000363614
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0008152metabolic process ----
GO:0046952ketone body catabolic process IEA--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for OXCT2 (SCOT2)

4 HMDB Compounds for OXCT2    About this table
CompoundSynonyms CAS #PubMed Ids
Acetoacetic acid3-Ketobutyrate (see all 9)541-50-4--
Acetoacetyl-CoA3-acetoacetyl-CoA (see all 9)1420-36-6--
Succinic acid1,2-Ethanedicarboxylate (see all 11)110-15-6--
Succinyl-CoACoenzyme A S-(hydrogen succinate) (see all 24)604-98-8--

1 DrugBank Compound for OXCT2    About this table
CompoundSynonyms CAS #TypeActionsPubMed Ids
Succinic acid1,2-Ethanedicarboxylic acid (see all 8)110-15-6target--17139284 17016423



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for OXCT2 gene: 
NM_022120.1  

Unigene Cluster for OXCT2:

3-oxoacid CoA transferase 2
Hs.472491  [show with all ESTs]
Unigene Representative Sequence: AK024440
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000327582(uc001ceb.1)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat OXCT2 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate OXCT2
SwitchGear 3'UTR luciferase reporter plasmidOXCT2 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for OXCT2
Predesigned siRNA for gene silencing in human, mouse, rat OXCT2
Clone
Products:
     
OriGene clones in human, mouse for OXCT2 (see all 7)
OriGene ORF clones in mouse, rat for OXCT2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: OXCT2 (NM_022120)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for OXCT2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OXCT2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for OXCT2
OriGene qSTAR qPCR primer pairs in human, mouse for OXCT2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OXCT2
  QuantiTect SYBR Green Assays in human, mouse, rat OXCT2
  QuantiFast Probe-based Assays in human, mouse, rat OXCT2

Additional mRNA sequence: 

AB050193.2 AK024440.1 AK093089.1 AK314586.1 AY013700.1 BC030015.1 BC072388.1 

3 DOTS entries:

DT.107641  DT.40295909  DT.92070015 

Selected AceView cDNA sequences (see all 27):

AA687627 BI825953 BV196560 BV204239 AK024440 BV204238 BU507864 BQ957658 
BV196088 BV190151 BC072388 BV196089 BV196559 BV196014 BV196013 BM800530 
BV196558 BE796223 BI825247 AA889705 AI825010 BM544983 H41231 BI462869 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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OXCT2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: CAGCAGGTGG
OXCT2 Expression
About this image


OXCT2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 2) fully expand
 
 Eye (Sensory Organs)
         Retina
 
 Testis (Reproductive System)
OXCT2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

OXCT2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.472491

UniProtKB/Swiss-Prot: SCOT2_HUMAN, Q9BYC2
Tissue specificity: Testis specific

    Pathway & Disease-focused RT2 Profiler PCR Arrays including OXCT2: 
          Fatty Acid Metabolism in human mouse rat
          Amino Acid Metabolism I in human mouse rat

Primer
Products:
OriGene qPCR primer pairs and template standards for OXCT2
OriGene qSTAR qPCR primer pairs in human, mouse for OXCT2
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OXCT2
QuantiTect SYBR Green Assays in human, mouse, rat OXCT2
QuantiFast Probe-based Assays in human, mouse, rat OXCT2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OXCT2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for OXCT2 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Oxct2b5 3-oxoacid CoA transferase 2B   --   4 (57.38 cM) 123116266 
chicken
(Gallus gallus)
Aves OXCT16
Gallus gallus 3-oxoacid CoA transferase 1 (OXCT1),...
71(a)
1 → many
Z(13039225-13121429)
lizard
(Anolis carolinensis)
Reptilia --
Succinyl-CoA:3-ketoacid-coenzyme A transferase
68(a)
1 → many
2(6594740-6669297)
zebrafish
(Danio rerio)
Actinopterygii oxct1a6
oxct1b6
3-oxoacid CoA transferase 1b
67(a)
64(a)
many ↔ many
many ↔ many
8(32565217-32666958) ENSDARG00000013063
21(19598957-19613763) ENSDARG00000054319
fruit fly
(Drosophila melanogaster)
Insecta CG11403 3-oxoacid CoA-transferase 59(a)   62B12   --
worm
(Caenorhabditis elegans)
Secernentea C05C10.33 3-oxoacid CoA-transferase 57(a)   II(9934457-9936798)   --


ENSEMBL Gene Tree for OXCT2 (if available)
TreeFam Gene Tree for OXCT2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for OXCT2 gene
OXCT12  
3 SIMAP similar genes for OXCT2 using alignment to 2 protein entries:     SCOT2_HUMAN (see all proteins):
FLJ00030    OXCT1    OXCT

Find genes that share paralogs with OXCT2           About GenesLikeMe


1 Pseudogenes.org Pseudogene for OXCT2
PGOHUM00000244680


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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3 SNPs for OXCT2    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1997077891,2
--40316353(-) TTACT-/TAATAATA 1 -- us2k10--------
rs75426091,2,4
----see VAR_0591342 mis40--------
rs2303211,2,4
----see VAR_0591352 mis40--------

HapMap Linkage Disequilibrium report for OXCT2 (40235195 - 40237020 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for OXCT2:    About this table    
Variant IDTypeSubtypePubMed ID
dgv215n71CNV Loss21882294
dgv15n27CNV Gain19166990
dgv49e1CNV Complex17122850
nsv7177OTHER Inversion18451855

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing OXCT2
DNA2.0 Custom Variant and Variant Library Synthesis for OXCT2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 610289    OMIM disorders: --


Find genes that share disorders with OXCT2           About GenesLikeMe


Export disorders for OXCT2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for OXCT2 gene integrated from 10 sources:
(articles sorted by number of sources associating them with OXCT2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Cloning and characterization of a human orthologue of testis-specific succinyl CoA:3-oxo acid CoA transferase (Scot-t) cDNA. (PubMed id 11756565)1, 2, 3, 9 Tanaka H.... Nishimune Y. (Mol. Hum. Reprod. 2002)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  3. Characterization of long cDNA clones from human adult spleen. (PubMed id 11214971)1, 3 Hattori A.... Ohara O. (DNA Res. 2000)
  4. Drugs, their targets and the nature and number of drug targets. (PubMed id 17016423)7 Imming P....Meyer A. (Nat Rev Drug Discov 2006)
  5. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (Nat Rev Drug Discov 2006)
  6. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. Dimeric pig heart succinate-coenzyme A transferase uses only one subunit to support catalysis. (PubMed id 11327867)1 Lloyd A.J. and Shoolingin-Jordan P.M. (Biochemistry 2001)
  10. Isolation and characterization of a haploid germ cell-specific novel complementary deoxyribonucleic acid; testis-specific homologue of succinyl CoA:3-Oxo acid CoA transferase. (PubMed id 11090426)9 Koga M....Nishimune Y. (Biol. Reprod. 2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
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OMIM
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 64064 HGNC: 18606 AceView: OXCT2P Ensembl:ENSG00000198754 euGenes: HUgn64064
ECgene: OXCT2 Kegg: 64064 H-InvDB: OXCT2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for OXCT2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for OXCT2 gene:
Search GeneIP for patents involving OXCT2

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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