Aliases for OVOL2 Gene
External Ids for OVOL2 Gene
Previous Symbols for OVOL2 Gene
GeneCards Summary for OVOL2 Gene
OVOL2 (Ovo-Like Zinc Finger 2) is a Protein Coding gene. Diseases associated with OVOL2 include corneal edema. GO annotations related to this gene include transcription regulatory region DNA binding and sequence-specific DNA binding RNA polymerase II transcription factor activity. An important paralog of this gene is OVOL1.
UniProtKB/Swiss-Prot for OVOL2 Gene
Zinc-finger transcription repressor factor. Plays a critical role to maintain the identity of epithelial lineages by suppressing epithelial-to mesenchymal transition mainly through the up-regulation of ZEB1 expression. Positively regulates neuronal differentiation (By similarity). Suppresses cell cycling and terminal differentiation of keratinocytes by directly repressing MYC and NOTCH1.