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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

OVOL2 Gene

protein-coding GIFtS: 45
GCID: GC20M017937

ovo-like 2 (Drosophila)

(Previous name: zinc finger protein 339 )
(Previous symbol: ZNF339)

Explore 3 diseases affiliated with
OVOL2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ovo-Like 2 (Drosophila)¹ ²		BA504H3.3¹
Zinc Finger Protein 339¹ ² ³		EUROIMAGE566589²
ZNF339¹ ² ³		Transcription Factor Ovo-Like 2²
HOvo2¹

External Ids:	HGNC: 15804¹	Entrez Gene: 58495²	Ensembl: ENSG00000125850⁷	UniProtKB: Q9BRP0³

Export aliases for OVOL2 gene to outside databases

Previous GC identifer: GC20M017947

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: OVOL2_HUMAN, Q9BRP0

Function: DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription

regulator (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011387.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the OVOL2 gene promoter:
MAZR SREBP-1c MyoD Nkx2-5 CUTL1 SREBP-1b PPAR-gamma1 SREBP-1a PPAR-gamma2 Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OVOL2 promoter sequence

Search SABiosciences Chromatin IP Primers for OVOL2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OVOL2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20pter-q11.23 Ensembl cytogenetic band: 20p11.23 HGNC cytogenetic band: 20q11.21-q11.23

OVOL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OVOL2 gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20M017937: view genomic region (about GC identifiers)

Start:	17,937,623 bp from pter	End:	18,039,832 bp from pter
Size:	102,210 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: OVOL2_HUMAN, Q9BRP0 (See protein sequence)

Recommended Name: Transcription factor Ovo-like 2

Size: 275 amino acids; 30438 Da

Subcellular location: Nucleus (Probable)

Secondary accessions: Q5T8B4 Q9BX22 Q9HA54 Q9Y4M0

Alternative splicing: 2 isoforms: Q9BRP0-1 Q9BRP0-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for OVOL2: NX_Q9BRP0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9BRP0

OVOL2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_067043.2

ENSEMBL proteins:

ENSP00000278780

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	Uscn Proteins for OVOL2

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

OVOL2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

OVOL2 for domains About GeneDecksing

3 InterPro domains/families:

IPR015880 Znf_C2H2-like

IPR013087 Znf_C2H2/integrase_DNA-bd

IPR007087 Znf_C2H2

Graphical View of Domain Structure for InterPro Entry Q9BRP0

ProtoNet protein and cluster: Q9BRP0

UniProtKB/Swiss-Prot: OVOL2_HUMAN, Q9BRP0

Similarity: Belongs to the krueppel C2H2-type zinc-finger protein family

Similarity: Contains 4 C2H2-type zinc fingers

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: OVOL2_HUMAN, Q9BRP0

Function: DNA-binding protein that binds to the 5'-G[GCT]GGGGG-3' core sequence. Probably acts as a transcription

regulator (By similarity)

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OVOL2
		8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate OVOL2 (see all 18):
		hsa-miR-579 hsa-miR-30c hsa-miR-498 hsa-miR-3607-3p hsa-miR-767-5p hsa-miR-30d hsa-miR-1297 hsa-miR-30a

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OVOL2

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0008270	zinc ion binding	IEA	--
GO:0044212	transcription regulatory region DNA binding	IDA	19700410

OVOL2 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for OVOL2:

Decreased Wnt reporter activit

Increased gamma-H2AX phosphory

Animal Models:
Mouse knock-out Ovol2^tm1Sito for OVOL2
11 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Ovol2):

cardiovascular system	cellular	craniofacial	digestive/alimentary	embryogenesis
growth/size	hearing/vestibular/ear	mortality/aging	muscle	nervous system
vision/eye

OVOL2 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for OVOL2

Gene Ontology (GO): 5/19 biological process terms (GO ID links to tree view) (see all 19): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001525	angiogenesis	IEA	--
GO:0001755	neural crest cell migration	IEA	--
GO:0001842	neural fold formation	IEA	--
GO:0001947	heart looping	IEA	--
GO:0006351	transcription, DNA-dependent	IEA	--

OVOL2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for OVOL2
Search CenterWatch for drugs/clinical trials and news about OVOL2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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About This Section

REFSEQ mRNAs for OVOL2 gene:

NM_021220.2

Unigene Clusters for OVOL2:

Ovo-like 2 (Drosophila)

Hs.661013 [show with all ESTs], Hs.710157 [show with all ESTs]

Unigene Representative Sequences: AK022284, NM_021220

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000486776 ENST00000278780(uc002wqi.1) ENST00000483661 ENST00000494030

ENST00000462208

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OVOL2
		8/18 QIAGEN miScript miRNA Assays for microRNAs that regulate OVOL2 (see all 18):
		hsa-miR-579 hsa-miR-30c hsa-miR-498 hsa-miR-3607-3p hsa-miR-767-5p hsa-miR-30d hsa-miR-1297 hsa-miR-30a

		SwitchGear 3'UTR luciferase reporter plasmid: OVOL2 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OVOL2 (see all 7) OriGene shRNA RFP: OVOL2 OriGene siRNA: OVOL2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OVOL2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OVOL2 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OVOL2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: OVOL2 (NM_021220)
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OVOL2

Additional cDNA sequence:

AL079276.1 BC006148.1 BT007295.1

9 DOTS entries:

DT.99954540 DT.40115232 DT.411255 DT.100695365 DT.100711911 DT.91818548 DT.92420239 DT.95159370

DT.92043341

24/614 AceView cDNA sequences (see all 614):

BQ649314 BE278898 CR621801 BE791524 AA282578 AU121853 BU957385 BM846071

AW135191 BI834833 AI336014 CR591673 AA705521 F04429 AI423332 NM_152227

BM996227 AA968703 N90980 AI129570 BQ082195 BG774314 NM_014426 BM973260

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

OVOL2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCCTGATGG

About this image

OVOL2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Line H9 (WA09) (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

Primitive gut tube-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See OVOL2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OVOL2

SOURCE GeneReport for Unigene clusters: Hs.661013 Hs.710157

UniProtKB/Swiss-Prot: OVOL2_HUMAN, Q9BRP0

Tissue specificity: Expressed in testis, ovary, heart and skeletal muscle

SABiosciences Custom PCR Arrays for OVOL2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OVOL2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for OVOL2 gene from 6/20 species (see all 20) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	OVOL2¹	ovo-like 2 (Drosophila)	72.9(n) 71.76(a)		416720 XM_415018.3 XP_415018.3
lizard (Anolis carolinensis)	Reptilia	OVOL2⁶	--	78(a)	1 ↔ 1	4(74463872-74469405)
African clawed frog (Xenopus laevis)	Amphibia	CA981310.1²	--	78.65(n)		CA981310.1
zebrafish (Danio rerio)	Actinopterygii	LOC100534921¹	putative transcription factor Ovo-like 1-like	54.87(n) 53.09(a)		100534921 XM_003200839.1 XP_003200887.1
fruit fly (Drosophila melanogaster)	Insecta	ovo⁶	ovo	8(a)	1 → many	X(4942330-4964962)
worm (Caenorhabditis elegans)	Secernentea	lin-48⁶	abnormal cell LINeage family member (lin-48)	31(a)	1 → many	III(3745443-3747330)

ENSEMBL Gene Tree for OVOL2 (if available)
TreeFam Gene Tree for OVOL2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for OVOL2 gene

OVOL3² OVOL1²

7 SIMAP similar genes for OVOL2 using alignment to 1 protein entry: OVOL2_HUMAN:

OVOL1 OVOL3 ZNF78L1 ZNF808 PLZF ZNF702P

ZNF844

OVOL2 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs141511721^1,2		--	18004329(+)	`CCCAT-/AAAAAA`	1	--	ds500¹		0	--	--	--	--
rs73899325^1,2	C,	--	18004435(+)	`TGGCCG/TTTTGT`	1	--	ds500¹		1		WA	2
rs3838381^1,2	C,	--	18004496(-)	`GAGAT-/TGGGGT`	1	--	ds500¹		0	--	--	--	--
rs191943096^1,2		--	18004521(+)	`AAATTA/GGCTGG`	1	--	ds500¹		0	--	--	--	--
rs3790294^1,2	C,F,H,	--	18004744(-)	`GTTATT/CGAGGT`	1	--	ds500¹ ese³		7		EA NS	2282
rs6136263^1,2	C	--	18004794(+)	`CTGTAA/GGTCAA`	1	--	ds500¹ ese³		0	--	--	--	--
rs183807880^1,2		--	18004900(+)	`CTTAAA/CCAGCA`	1	--	ut3¹		0	--	--	--	--
rs189170164^1,2		--	18004977(+)	`CTTCCA/GTGTGT`	1	--	ut3¹		0	--	--	--	--
rs7266320^1,2	C,	--	18004996(+)	`TTGGGG/CGAAAA`	1	--	ut3¹ ese³ trp³		1		WA	2
rs3215639^1,2	C,	--	18004998(+)	`GGGGGA/-AAAAA`	1	--	ut3¹ trp³		1		NA	2

HapMap Linkage Disequilibrium report for OVOL2 (17937623 - 18039832 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for OVOL2: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OVOL2

DNA2.0 Custom Variant and Variant Library Synthesis for OVOL2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OVOL2 for disorders About GeneDecksing

3 diseases for OVOL2: About MalaCards

corneal edema blindness neuronitis

1 disease from the University of Copenhagen DISEASES database for OVOL2:

Corneal edema

Export disorders for OVOL2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for OVOL2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with OVOL2)

Utopia: connect your pdf to the dynamic
world of online information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Ovol2, a mammalian homolog of Drosophila ovo: gene structure, chromosomal mapping, and aberrant expression in blind-sterile mice. (PubMed id 12213202)^{1, 2} Li B.... Dai X. (2002)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Molecular phylogeny of OVOL genes illustrates a conser ved C2H2 zinc finger domain coupled by hypervariable unstructured regions. (PubMed id 22737237)¹ Kumar A....Grapputo A. (2012)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Ovol2 suppresses cell cycling and terminal differenti ation of keratinocytes by directly repressing c-Myc and Notch1. (PubMed id 19700410)¹ Wells J....Dai X. (2009)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 58495	HGNC: 15804	AceView: SNX5andZNF339	Ensembl:ENSG00000125850	euGenes: HUgn58495
ECgene: OVOL2	H-InvDB: OVOL2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for OVOL2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for OVOL2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for OVOL2 gene:
Search GeneIP for patents involving OVOL2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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Advanced Cell Diagnostics
About This Section


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	OriGene Antibodies for OVOL2		OriGene shRNA RFP for OVOL2
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OVOL2		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OVOL2
	OriGene Protein Over-expression Lysate for OVOL2		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for OVOL2		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OVOL2		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OVOL2
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for OVOL2		OriGene Custom Protein Services for OVOL2
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OVOL2
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OVOL2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OVOL2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OVOL2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OVOL2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OVOL2

	GenScript Custom Purified and Recombinant Proteins Services for OVOL2		GenScript cDNA clones with any tag delivered in your preferred vector for OVOL2
	GenScript Custom Assay Services for OVOL2		GenScript Custom Superior Antibodies Services for OVOL2
	GenScript Custom overexpressing Cell Line Services for OVOL2		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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	OVOL2 lysates

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OVOL2 Proteins, Antibodies, CLIAs, and ELISAs

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	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OVOL2

	SwitchGear 3'UTR luciferase reporter plasmids for OVOL2
	SwitchGear Promoter luciferase reporter plasmids for OVOL2

Search ThermoFisher Antibodies for OVOL2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OVOL2

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes OVOL2 gene at Home site.

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OVOL2 Gene

ovo-like 2 (Drosophila)

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OVOL2 Gene

ovo-like 2 (Drosophila)

Aliasesfor OVOL2 gene

Summariesfor OVOL2 gene

Genomic Viewsfor OVOL2 gene

Proteinsfor OVOL2 gene

Protein Domains /Familiesfor OVOL2 gene

Functionfor OVOL2 gene

Pathways & Interactionsfor OVOL2 gene

Drugs & Compoundsfor OVOL2 gene

Transcriptsfor OVOL2 gene

Expression for OVOL2 gene

Orthologsfor OVOL2 gene

Paralogsfor OVOL2 gene

Genomic Variantsfor OVOL2 gene

Disorders / Diseasesfor OVOL2 gene

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External Searches for OVOL2 gene

Genome Databases showing OVOL2 gene

Other Databases showing OVOL2 gene

Specialized Databases showing OVOL2 gene

Intellectual Propertyfor OVOL2 gene

Productsfor OVOL2 gene

View Random Gene

Aliases
for OVOL2 gene

Summaries
for OVOL2 gene

Genomic Views
for OVOL2 gene

Proteins
for OVOL2 gene

Protein Domains /
Families
for OVOL2 gene

Function
for OVOL2 gene

Pathways & Interactions
for OVOL2 gene

Drugs & Compounds
for OVOL2 gene

Transcripts
for OVOL2 gene

Expression
for OVOL2 gene

Orthologs
for OVOL2 gene

Paralogs
for OVOL2 gene

Genomic Variants
for OVOL2 gene

Disorders / Diseases
for OVOL2 gene

Publications
for OVOL2 gene

Intellectual Property
for OVOL2 gene

Products
for OVOL2 gene