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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OVOL1 Gene

protein-coding   GIFtS: 52
GCID: GC11P065555

Ovo-Like 1(Drosophila)

(Previous name: ovo (Drosophila) homolog-like 1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ovo-Like 1(Drosophila)1 2
Ovo (Drosophila) Homolog-Like 11
HOVO12
Ovo Homolog-Like 12
Putative Transcription Factor Ovo-Like 12
hOvo13

External Ids:    HGNC: 85251   Entrez Gene: 50172   Ensembl: ENSG000001728187   OMIM: 6023135   UniProtKB: O147533   

Export aliases for OVOL1 gene to outside databases

Previous GC identifers: GC11P068095 GC11P067242 GC11P065804 GC11P065330 GC11P065329 GC11P065311 GC11P061863


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OVOL1 Gene:
This gene encodes a putative zinc finger containing transcription factor that is highly similar to homologous
protein in Drosophila and mouse. Based on known functions in these species, this protein is likely involved in
hair formation and spermatogenesis in human as well. (provided by RefSeq, Aug 2011)

GeneCards Summary for OVOL1 Gene: 
OVOL1 (ovo-like 1(Drosophila)) is a protein-coding gene. Diseases associated with OVOL1 include kidney disease, and atopic dermatitis. GO annotations related to this gene include RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription and DNA binding. An important paralog of this gene is GFI1.

UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753
Function: Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the
differentiation and/or maintenance of the urogenital system (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_167190.1  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OVOL1 gene promoter:
         NF-1   STAT1   Pax-5   STAT1beta   Nkx2-5   STAT1alpha   AREB6   ZID   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOVOL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for OVOL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OVOL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13

OVOL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OVOL1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P065555:  view genomic region     (about GC identifiers)

Start:
65,554,493 bp from pter      End:
65,564,690 bp from pter
Size:
10,198 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753 (See protein sequence)
Recommended Name: Putative transcription factor Ovo-like 1  
Size: 267 amino acids; 30259 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q6PCB1

Explore the universe of human proteins at neXtProt for OVOL1: NX_O14753

Explore proteomics data for OVOL1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O14753

  • OVOL1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OVOL1 Protein Expression
    REFSEQ proteins: NP_004552.2  
    ENSEMBL proteins: 
     ENSP00000337862   ENSP00000434220  

    Human Recombinant Protein Products for OVOL1: 
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    Novus Biologicals OVOL1 Proteins
    Novus Biologicals OVOL1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OVOL1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--

    OVOL1 for ontologies           About GeneDecksing



    OVOL1 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for OVOL1 

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    Cloud-Clone Corp. CLIAs for OVOL1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry O14753

    ProtoNet protein and cluster: O14753

    1 Blocks protein domain: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753
    Similarity: Contains 4 C2H2-type zinc fingers


    OVOL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OVOL1_HUMAN, O14753
    Function: Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the
    differentiation and/or maintenance of the urogenital system (By similarity)

         Genatlas biochemistry entry for OVOL1:
    Drosophila OVO gene homolog,female germline-specific nuclear protein,expressed in placenta,fetal kidney,pancreas

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity IBA--
    GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription IEA--
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding ----
         
    OVOL1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for OVOL1:
     Increased S DNA content 

         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ovol1):
     endocrine/exocrine gland  growth/size  homeostasis/metabolism  integument  mortality/aging 
     renal/urinary system  reproductive system 

    OVOL1 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Ovol1tm1Efu for OVOL1

       inGenious Targeting Laboratory - Custom generated mouse model solutions for OVOL1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OVOL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OVOL1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OVOL1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OVOL1
    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate OVOL1 (see all 26):
    hsa-miR-30c hsa-miR-125a-5p hsa-miR-1224-3p hsa-miR-1271 hsa-miR-30d hsa-miR-340 hsa-miR-4267 hsa-miR-633
    SwitchGear 3'UTR luciferase reporter plasmidOVOL1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Clone
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    OriGene clones in human, mouse for OVOL1 (see all 7)
    OriGene ORF clones in mouse, rat for OVOL1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OVOL1 (NM_004561)
    Browse Sino Biological Human cDNA Clones
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                         Customized lentivirus expression plasmids for stable overexpression of OVOL1 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OVOL1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OVOL1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for OVOL1 (O147533 ENSP000003378624) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HDAC3O153793, ENSP000003029674I2D: score=1 STRING: ENSP00000302967
    HDAC1Q135473, ENSP000003626494I2D: score=1 STRING: ENSP00000362649
    HDAC2Q927693, ENSP000003813314I2D: score=1 STRING: ENSP00000381331
    MAFFENSP000003453934STRING: ENSP00000345393
    About this table

    Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ----
    GO:0001822kidney development IEA--
    GO:0006366transcription from RNA polymerase II promoter IBA--
    GO:0007283spermatogenesis IEA--
    GO:0007498mesoderm development IEA--

    OVOL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OVOL1

    Search CenterWatch for drugs/clinical trials and news about OVOL1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OVOL1 gene: 
    NM_004561.3  

    Unigene Cluster for OVOL1:

    Ovo-like 1(Drosophila)
    Hs.134434  [show with all ESTs]
    Unigene Representative Sequence: NM_004561
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335987(uc001ofp.3 uc001ofq.3) ENST00000531907 ENST00000532448

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OVOL1
    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate OVOL1 (see all 26):
    hsa-miR-30c hsa-miR-125a-5p hsa-miR-1224-3p hsa-miR-1271 hsa-miR-30d hsa-miR-340 hsa-miR-4267 hsa-miR-633
    SwitchGear 3'UTR luciferase reporter plasmidOVOL1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for OVOL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OVOL1
    Clone
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    OriGene clones in human, mouse for OVOL1 (see all 7)
    OriGene ORF clones in mouse, rat for OVOL1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OVOL1 (NM_004561)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OVOL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OVOL1
    Sirion Biotech Customized lentivirus for stable overexpression of OVOL1 
                         Customized lentivirus expression plasmids for stable overexpression of OVOL1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for OVOL1
    OriGene qSTAR qPCR primer pairs in human, mouse for OVOL1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OVOL1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OVOL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OVOL1

    Additional mRNA sequence: 

    AK291711.1 BC043146.1 BC059408.1 BX648725.1 

    2 DOTS entries:

    DT.97767299  DT.408136 

    24/56 AceView cDNA sequences (see all 56):

    BC043146 BF772382 BP369631 AI075228 CB852898 BU678551 BX648725 AW207443 
    AL702845 AL702846 BX094609 NM_004561 AW453082 BV198906 AW207036 CD171850 
    AA992356 BX337110 BC059408 AI811656 AW732967 AW204720 CD050473 AW340064 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for OVOL1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
    SP1:        -     -     -     -     -                                 
    SP2:              -     -     -     -                                 
    SP3:                          -                                       
    SP4:                                                                  


    ECgene alternative splicing isoforms for OVOL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OVOL1 expression in normal human tissues (normalized intensities)      OVOL1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGCTCTGTG
    OVOL1 Expression
    About this image


    OVOL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Pancreas (Endocrine System)
             Pancreatic endoderm/endocrine precursor-like cells ( A scalable, suspension protocol...
     
     Epidermis (Integumentary System)
             Spinous Keratinocytes Stratified Epidermis
     
     Nose (Sensory Organs)
             sensory organ/nose/naris   
     
     Kidney (Urinary System)
             renal vesicle e12.5   
     
     Testis (Reproductive System)

    See OVOL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OVOL1

    SOURCE GeneReport for Unigene cluster: Hs.134434

    UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753
    Tissue specificity: Expressed in fetal kidney, and also in adult pancreas and placenta. Not expressed in
    intestine, peripheral blood lymphocytes and ovary

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OVOL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for OVOL1 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ovol11 , 5 OVO homolog-like 1 (Drosophila)1, 5 90.14(n)1
    95.51(a)1
      19 (4.34 cM)5
    184261  NM_019935.31  NP_064319.11 
     55491375 
    zebrafish
    (Danio rerio)
    Actinopterygii ovol11 ovo-like 1 (Drosophila) 63.35(n)
    61.19(a)
      792456  NM_001114744.1  NP_001108216.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta ovo3 cuticle biosynthesis RNA polymerase II
    transcription more
    72(a)   1 4E2   --
    worm
    (Caenorhabditis elegans)
    Secernentea lin-483 Zinc finger, C2H2 type (3 domains) 67(a)   III(3817034-3818187)   --


    ENSEMBL Gene Tree for OVOL1 (if available)
    TreeFam Gene Tree for OVOL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OVOL1 gene
    GFI12  OVOL22  GFI1B2  OVOL32  FEZF12  FEZF22  
    18/20 SIMAP similar genes for OVOL1 using alignment to 3 protein entries:     OVOL1_HUMAN (see all proteins) (see all similar genes):
    OVOL2    OVOL3    ZNF55    kr-znf3    ZFS-5    ZFX
    DKFZp686N0199    HZF16    ZNF78L1    ZNF    ZNF814    A-328A3.4
    ZNF227    DKFZp434J0650    PLZF    ZFS-2    ZNF133    ZNF236

    OVOL1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/270 SNPs in OVOL1 are shown (see all 270)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs5628151,2
    C--65552668(-) TTCAGG/ATGCAC 1 -- us2k112Minor allele frequency- A:0.01NA WA CSA EA 374
    rs1460946501,2
    --65552693(+) CTGCCA/GTTTAG 1 -- us2k10--------
    rs6637971,2
    C,F--65552740(-) GCCGTC/TGGGGA 1 -- us2k112Minor allele frequency- T:0.25MN NA WA CSA EA 558
    rs1392692101,2
    --65552741(+) CCCCAA/GCGGCC 1 -- us2k10--------
    rs5619241,2
    C,F--65552743(-) CTGGCC/AGTCGG 1 -- us2k17Minor allele frequency- A:0.16MN NA EA 432
    rs775194501,2
    C--65552774(+) TGAATT/CTGTAG 1 -- us2k12Minor allele frequency- C:0.09CSA WA 120
    rs1425852061,2
    --65552795(+) CCATAC/TCTATG 1 -- us2k10--------
    rs790138381,2
    C,F--65552862(+) GGATAT/CTCATT 1 -- us2k11Minor allele frequency- C:0.07WA 118
    rs2005936231,2
    --65552872(+) TCATT-/CAACAAAC 1 -- us2k10--------
    rs1392616691,2
    C--65552873(+) CATTC-/AACA  
            
    AACAT
    1 -- us2k10--------

    HapMap Linkage Disequilibrium report for OVOL1 (65554493 - 65564690 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for OVOL1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv897760CNV Loss21882294
    nsv897758CNV Loss21882294
    nsv897718CNV Loss21882294
    nsv897736CNV Loss21882294
    dgv393e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602313    OMIM disorders: --

    3 diseases for OVOL1:    About MalaCards
    kidney disease    atopic dermatitis    dermatitis


    OVOL1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): OVOL1
    Human Genome Epidemiology (HuGE) Navigator: OVOL1 (1 document)

    Export disorders for OVOL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OVOL1 gene, integrated from 9 sources (see all 17):
    (articles sorted by number of sources associating them with OVOL1)
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    1. Characterization of a human homolog (OVOL1) of the Drosophila ovo gene, which maps to chromosome 11q13. (PubMed id 9383297)1, 2, 3 Chidambaram A.... Dean M. (1997)
    2. Meta-analysis of genome-wide association studies ident ifies three new risk loci for atopic dermatitis. (PubMed id 22197932)1, 4 Paternoster L....Weidinger S. (2012)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Large-scale genotyping identifies 41 new loci associat ed with breast cancer risk. (PubMed id 23535729)1 Michailidou K....Easton D.F. (2013)
    6. Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. (PubMed id 23263486)1 Kottgen A....Gieger C. (2013)
    7. Molecular phylogeny of OVOL genes illustrates a conser ved C2H2 zinc finger domain coupled by hypervariable unstructured regions. (PubMed id 22737237)1 Kumar A....Grapputo A. (2012)
    8. Genome-wide association study identifies eight new sus ceptibility loci for atopic dermatitis in the Japanese population. (PubMed id 23042114)1 Hirota T....Tamari M. (2012)
    9. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    10. New loci associated with kidney function and chronic kidney disease. (PubMed id 20383146)1 KAPttgen A....Fox C.S. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5017 HGNC: 8525 AceView: OVOL1 Ensembl:ENSG00000172818 euGenes: HUgn5017
    ECgene: OVOL1 H-InvDB: OVOL1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OVOL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OVOL1 gene:
    Search GeneIP for patents involving OVOL1

    GeneCards and IP:
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