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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OVOL1 Gene

protein-coding   GIFtS: 53
GCID: GC11P065555

ovo-like 1(Drosophila)

(Previous name: ovo (Drosophila) homolog-like 1 )
 Explore 2 diseases affiliated with
OVOL1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for OVOL1    

Aliases
for OVOL1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Ovo-Like 1(Drosophila)1 2
Ovo (Drosophila) Homolog-Like 11
HOVO12
Ovo Homolog-Like 12
Putative Transcription Factor Ovo-Like 12
HOvo11

External Ids:    HGNC: 85251   Entrez Gene: 50172   Ensembl: ENSG000001728187   OMIM: 6023135   UniProtKB: O147533   

Export aliases for OVOL1 gene to outside databases

Previous GC identifers: GC11P068095 GC11P067242 GC11P065804 GC11P065330 GC11P065329 GC11P065311 GC11P061863


Summaries
for OVOL1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for OVOL1:
This gene encodes a putative zinc finger containing transcription factor that is highly similar to homologous protein
in Drosophila and mouse. Based on known functions in these species, this protein is likely involved in hair formation
and spermatogenesis in human as well. (provided by RefSeq, Aug 2011)

UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753
Function: Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the
differentiation and/or maintenance of the urogenital system (By similarity)




Genomic Views
for OVOL1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OVOL1 gene promoter:
         NF-1   STAT1   Pax-5   STAT1beta   Nkx2-5   STAT1alpha   AREB6   ZID   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OVOL1 promoter sequence
   Search SABiosciences Chromatin IP Primers for OVOL1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OVOL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13

OVOL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OVOL1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P065555:  view genomic region     (about GC identifiers)

Start:
 65,554,493 bp from pter      End:
 65,564,690 bp from pter
Size:
 10,198 bases      Orientation:
 plus strand

Proteins
for OVOL1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753 (See protein sequence)
Recommended Name: Putative transcription factor Ovo-like 1  
Size: 267 amino acids; 30259 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: Q6PCB1

Explore the universe of human proteins at neXtProt for OVOL1: NX_O14753

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O14753

    • OVOL1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004552.2  
    ENSEMBL proteins: 
     ENSP00000337862   ENSP00000434220  

    Human Recombinant Protein Products: 
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    Novus Biologicals OVOL1 Proteins
    Novus Biologicals OVOL1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for OVOL1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--


    OVOL1 for ontologies           About GeneDecksing



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    Uscn Antibodies for OVOL1
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    Uscn ELISAs and CLIAs for OVOL1

    Protein Domains /
    Families
    for OVOL1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    OVOL1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry O14753

    ProtoNet protein and cluster: O14753

    1 Blocks protein family: IPB007086 C2H2-type zinc finger signature

    UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753
    Similarity: Contains 4 C2H2-type zinc fingers


    Function
    for OVOL1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753
    Function: Putative transcription factor. Involved in hair formation and spermatogenesis. May function in the
    differentiation and/or maintenance of the urogenital system (By similarity)

         Genatlas biochemistry entry for OVOL1:
    Drosophila OVO gene homolog,female germline-specific nuclear protein,expressed in placenta,fetal kidney,pancreas

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OVOL1
    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate OVOL1 (see all 26):
    hsa-miR-30c hsa-miR-125a-5p hsa-miR-1224-3p hsa-miR-1271 hsa-miR-30d hsa-miR-340 hsa-miR-4267 hsa-miR-633
    SwitchGear 3'UTR luciferase reporter plasmid: OVOL1 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OVOL1 (see all 7)
    OriGene shRNA RFP: OVOL1
    OriGene siRNA: OVOL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OVOL1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for OVOL1

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OVOL1 (see all 3)
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    Cell Line
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    Search LifeMap BioReagents cell lines for OVOL1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OVOL1

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription IEA--
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding IEA--


    OVOL1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for OVOL1:
     Increased S DNA content 

    Animal Models:
         Mouse knock-out Ovol1tm1Efu for OVOL1
         7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ovol1):
     endocrine/exocrine gland  growth/size  homeostasis/metabolism  integument  mortality/aging 
     renal/urinary system  reproductive system 

    OVOL1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for OVOL1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OVOL1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for OVOL1 (O147533 ENSP000003378624) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HDAC3O153793, ENSP000003029674I2D: score=1 STRING: ENSP00000302967
    HDAC1Q135473, ENSP000003626494I2D: score=1 STRING: ENSP00000362649
    HDAC2Q927693, ENSP000003813314I2D: score=1 STRING: ENSP00000381331
    MAFFENSP000003453934STRING: ENSP00000345393
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ----
    GO:0000239pachytene IEA--
    GO:0001822kidney development IEA--
    GO:0007283spermatogenesis IEA--
    GO:0007498mesoderm development IEA--


    OVOL1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for OVOL1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OVOL1
    Search CenterWatch for drugs/clinical trials and news about OVOL1 

    Transcripts
    for OVOL1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for OVOL1 gene: 
    NM_004561.3  

    Unigene Cluster for OVOL1:

    Ovo-like 1(Drosophila)
    Hs.134434  [show with all ESTs]
    Unigene Representative Sequence: NM_004561
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335987(uc001ofp.3 uc001ofq.3) ENST00000531907 ENST00000532448


    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OVOL1
    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate OVOL1 (see all 26):
    hsa-miR-30c hsa-miR-125a-5p hsa-miR-1224-3p hsa-miR-1271 hsa-miR-30d hsa-miR-340 hsa-miR-4267 hsa-miR-633
    SwitchGear 3'UTR luciferase reporter plasmid: OVOL1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OVOL1 (see all 7)
    OriGene shRNA RFP: OVOL1
    OriGene siRNA: OVOL1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OVOL1
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OVOL1
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    GenScript: all cDNA clones in your preferred vector: OVOL1 (NM_004561)
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    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OVOL1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OVOL1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OVOL1

    Additional cDNA sequence: 

    AK291711.1 BC043146.1 BC059408.1 BX648725.1 

    2 DOTS entries:

    DT.97767299  DT.408136 

    24/56 AceView cDNA sequences (see all 56):

    BC043146 AW453082 BP369631 BF772382 AI075228 BX648725 AW207443 NM_004561 
    BX094609 AL702846 AL702845 CB852898 BU678551 AW732967 BV198906 CB961078 
    AI811656 AW207036 BX337075 AA256695 BX337110 AW188136 BI561897 CA311282 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for OVOL1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
    SP1:        -     -     -     -     -                                 
    SP2:              -     -     -     -                                 
    SP3:                          -                                       
    SP4:                                                                  


    ECgene alternative splicing isoforms for OVOL1

    Expression
    for OVOL1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OVOL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGCTCTGTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    OVOL1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Pancreatic endoderm/endocrine precursor-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See OVOL1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OVOL1

    SOURCE GeneReport for Unigene cluster: Hs.134434

    UniProtKB/Swiss-Prot: OVOL1_HUMAN, O14753
    Tissue specificity: Expressed in fetal kidney, and also in adult pancreas and placenta. Not expressed in intestine,
    peripheral blood lymphocytes and ovary

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    In Situ
    Assay Products:     
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    Orthologs
    for OVOL1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for OVOL1 gene from 3/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    zebrafish
    (Danio rerio)    		 Actinopterygii ovol11 ovo-like 1 (Drosophila) 63.35(n)
    61.19(a)    		   792456  NM_001114744.1  NP_001108216.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta ovo3 cuticle biosynthesis RNA polymerase II
    transcription more    		 72(a)   1 4E2   --
    worm
    (Caenorhabditis elegans)    		 Secernentea lin-483 Zinc finger, C2H2 type (3 domains) 67(a)   III(3817034-3818187)   --


    ENSEMBL Gene Tree for OVOL1 (if available)
    TreeFam Gene Tree for OVOL1 (if available) 

    Paralogs
    for OVOL1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OVOL1 gene
    OVOL22  OVOL32  
    18/26 SIMAP similar genes for OVOL1 using alignment to 3 protein entries:     OVOL1_HUMAN (see all proteins) (see all similar genes):
    OVOL2    OVOL3    ZNF55    kr-znf3    ZFS-5    ZFX
    DKFZp686N0199    HZF16    ZNF78L1    ZNF    ZNF814    A-328A3.4
    ZNF227    DKFZp434J0650    PLZF    ZFS-2    ZNF133    ZNF236

    OVOL1 for paralogs           About GeneDecksing



    Genomic Variants
    for OVOL1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/213 NCBI SNPs in OVOL1 are shown (see all 213)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 11 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1112948931,2
    		C,--65552516(+) TCCAGC/-CCAGG 1 -- us2k11Minor allele frequency- -:0.00CSA 2
    rs360032021,2
    		C--65552517(+) AGCCAC/-GGCGA 1 -- us2k11Minor allele frequency- -:0.00NA 2
    rs5628151,2
    		C,--65552668(-) TTCAGG/ATGCAC 1 -- us2k112Minor allele frequency- A:0.01NA WA CSA EA 374
    rs1460946501,2
    		--65552693(+) CTGCCA/GTTTAG 1 -- us2k10--------
    rs6637971,2
    		C,F,--65552740(-) GCCGTC/TGGGGA 1 -- us2k112Minor allele frequency- T:0.25MN NA WA CSA EA 558
    rs1392692101,2
    		--65552741(+) CCCCAA/GCGGCC 1 -- us2k10--------
    rs5619241,2
    		C,F,--65552743(-) CTGGCC/AGTCGG 1 -- us2k17Minor allele frequency- A:0.16MN NA EA 432
    rs775194501,2
    		C,--65552774(+) TGAATT/CTGTAG 1 -- us2k12Minor allele frequency- C:0.09CSA WA 120
    rs1425852061,2
    		--65552795(+) CCATAC/TCTATG 1 -- us2k10--------
    rs790138381,2
    		C,F,--65552862(+) GGATAT/CTCATT 1 -- us2k11Minor allele frequency- C:0.07WA 118

    HapMap Linkage Disequilibrium report for OVOL1 (65554493 - 65564690 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for OVOL1
         1 CNV: 3855

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OVOL1
    DNA2.0 Custom Variant and Variant Library Synthesis for OVOL1

    Disorders / Diseases
    for OVOL1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OVOL1 for disorders           About GeneDecksing

    OMIM gene information: 602313    OMIM disorders: --

    2 diseases for OVOL1:    About MalaCards
    kidney disease    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: OVOL1 (1 document)

    Export disorders for OVOL1 gene to outside databases

    Publications
    for OVOL1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OVOL1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with OVOL1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a human homolog (OVOL1) of the Drosophila ovo gene, which maps to chromosome 11q13. (PubMed id 9383297)1, 2, 3 Chidambaram A.... Dean M. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Meta-analysis of genome-wide association studies ident ifies three new risk loci for atopic dermatitis. (PubMed id 22197932)1 Paternoster L....Weidinger S. (2012)
    4. Molecular phylogeny of OVOL genes illustrates a conser ved C2H2 zinc finger domain coupled by hypervariable unstructured regions. (PubMed id 22737237)1 Kumar A....Grapputo A. (2012)
    5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    6. New loci associated with kidney function and chronic kidney disease. (PubMed id 20383146)1 KAPttgen A....Fox C.S. (2010)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    8. Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity. (PubMed id 17311813)1 Nair M....Dai X. (2007)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
    10. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)

    External Searches for OVOL1 gene

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    Genome Databases showing OVOL1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 5017 HGNC: 8525 AceView: OVOL1 Ensembl:ENSG00000172818 euGenes: HUgn5017
    ECgene: OVOL1 H-InvDB: OVOL1

    Other Databases showing OVOL1 gene

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    Specialized Databases showing OVOL1 gene

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    PharmGKB entry for OVOL1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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