Aliases for OVGP1 Gene
External Ids for OVGP1 Gene
Previous HGNC Symbols for OVGP1 Gene
Previous GeneCards Identifiers for OVGP1 Gene
This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008]
GeneCards Summary for OVGP1 Gene
OVGP1 (Oviductal Glycoprotein 1) is a Protein Coding gene. Diseases associated with OVGP1 include Chronic Salpingitis and Acute Salpingitis. Among its related pathways are Fertilization. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and chitinase activity. An important paralog of this gene is CHIT1.
UniProtKB/Swiss-Prot for OVGP1 Gene
Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.