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Aliases for OVCH1 Gene

Aliases for OVCH1 Gene

  • Ovochymase 1 2 3
  • Ovochymase-1 3
  • EC 3.4.21.- 4
  • EC 3.4.21 63
  • OVCH 3

External Ids for OVCH1 Gene

Previous GeneCards Identifiers for OVCH1 Gene

  • GC12M029476
  • GC12U900395
  • GC12M029471
  • GC12M029580

Summaries for OVCH1 Gene

GeneCards Summary for OVCH1 Gene

OVCH1 (Ovochymase 1) is a Protein Coding gene. GO annotations related to this gene include serine-type endopeptidase activity. An important paralog of this gene is PRSS56.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OVCH1 Gene

Genomics for OVCH1 Gene

Regulatory Elements for OVCH1 Gene

Genomic Location for OVCH1 Gene

29,412,474 bp from pter
29,497,686 bp from pter
85,213 bases
Minus strand

Genomic View for OVCH1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OVCH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OVCH1 Gene

Proteins for OVCH1 Gene

  • Protein details for OVCH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein Accession:
    Secondary Accessions:

    Protein attributes for OVCH1 Gene

    1134 amino acids
    Molecular mass:
    125066 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OVCH1 Gene

Proteomics data for OVCH1 Gene at MOPED

Selected DME Specific Peptides for OVCH1 Gene

Post-translational modifications for OVCH1 Gene

  • Glycosylation at Asn52, Asn99, Asn324, Asn431, Asn507, and Asn1106
  • Modification sites at PhosphoSitePlus

Other Protein References for OVCH1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains for OVCH1 Gene

Suggested Antigen Peptide Sequences for OVCH1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 3 CUB domains.
  • Belongs to the peptidase S1 family.
  • Contains 3 CUB domains.
  • Contains 2 peptidase S1 domains.
  • Belongs to the peptidase S1 family.
genes like me logo Genes that share domains with OVCH1: view

No data available for Gene Families for OVCH1 Gene

Function for OVCH1 Gene

Enzyme Numbers (IUBMB) for OVCH1 Gene

Gene Ontology (GO) - Molecular Function for OVCH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003824 catalytic activity --
GO:0004252 serine-type endopeptidase activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with OVCH1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OVCH1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OVCH1 Gene

Localization for OVCH1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OVCH1 Gene


Subcellular locations from

Jensen Localization Image for OVCH1 Gene COMPARTMENTS Subcellular localization image for OVCH1 gene
Compartment Confidence
extracellular 2
plasma membrane 2
cytoskeleton 1
cytosol 1
endoplasmic reticulum 1
golgi apparatus 1
lysosome 1
nucleus 1

Gene Ontology (GO) - Cellular Components for OVCH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with OVCH1: view

Pathways for OVCH1 Gene

SuperPathways for OVCH1 Gene

No Data Available

Interacting Proteins for OVCH1 Gene

Gene Ontology (GO) - Biological Process for OVCH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
genes like me logo Genes that share ontologies with OVCH1: view

No data available for Pathways by source for OVCH1 Gene

Transcripts for OVCH1 Gene

mRNA/cDNA for OVCH1 Gene

(7) REFSEQ mRNAs :
(5) Selected AceView cDNA sequences:
(0) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OVCH1 Gene

Ovochymase 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OVCH1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OVCH1 Gene

No ASD Table

Relevant External Links for OVCH1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OVCH1 Gene

mRNA expression in normal human tissues for OVCH1 Gene

mRNA differential expression in normal tissues according to GTEx for OVCH1 Gene

This gene is overexpressed in Testis (4.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OVCH1 Gene

SOURCE GeneReport for Unigene cluster for OVCH1 Gene Hs.674588

genes like me logo Genes that share expressions with OVCH1: view

Expression partners for OVCH1 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OVCH1 Gene

Orthologs for OVCH1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OVCH1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OVCH1 35
  • 80.69 (n)
  • 70.74 (a)
OVCH1 36
  • 60 (a)
(Pan troglodytes)
Mammalia OVCH1 35
  • 98.27 (n)
  • 97.5 (a)
OVCH1 36
  • 97 (a)
(Canis familiaris)
Mammalia OVCH1 36
  • 73 (a)
(Ornithorhynchus anatinus)
Mammalia OVCH1 36
  • 35 (a)
(Anolis carolinensis)
Reptilia OVCH1 36
  • 40 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia ovch1 35
  • 51.31 (n)
  • 39.18 (a)
(Danio rerio)
Actinopterygii zgc:55888 35
  • 44.95 (n)
  • 34.62 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG11668 36
  • 19 (a)
CG11670 36
  • 19 (a)
CG11836 36
  • 34 (a)
CG11841 36
  • 20 (a)
CG11842 36
  • 22 (a)
CG11843 36
  • 23 (a)
CG1299 36
  • 22 (a)
CG14642 36
  • 23 (a)
CG14892 36
  • 22 (a)
CG18735 36
  • 30 (a)
CG31728 36
  • 22 (a)
CG32260 36
  • 19 (a)
CG3355 36
  • 31 (a)
CG34350 36
  • 14 (a)
CG3700 36
  • 22 (a)
CG4386 36
  • 27 (a)
CG4613 36
  • 28 (a)
CG4914 36
  • 31 (a)
CG4927 36
  • 21 (a)
CG6361 36
  • 17 (a)
CG6865 36
  • 28 (a)
CG7432 36
  • 18 (a)
CG8172 36
  • 18 (a)
CG8213 36
  • 9 (a)
CG9294 36
  • 30 (a)
CG9372 36
  • 24 (a)
psh 36
  • 20 (a)
Sb 36
  • 16 (a)
snk 36
  • 19 (a)
spirit 36
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.6617 36
  • 34 (a)
Species with no ortholog for OVCH1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OVCH1 Gene

Gene Tree for OVCH1 (if available)
Gene Tree for OVCH1 (if available)

Paralogs for OVCH1 Gene

Paralogs for OVCH1 Gene

genes like me logo Genes that share paralogs with OVCH1: view

Variants for OVCH1 Gene

Sequence variations from dbSNP and Humsavar for OVCH1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs182550845 -- 29,495,938(+) CTCTA(C/T)CCAAG intron-variant
rs182408339 -- 29,489,318(+) TAGGC(C/T)TAATA intron-variant
rs181656932 -- 29,491,933(+) CTCAA(C/T)GAATG intron-variant
rs180949225 -- 29,499,092(+) CTGAA(C/G)AGTGG upstream-variant-2KB
rs180706309 -- 29,493,118(+) AGGAA(A/G)CGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OVCH1 Gene

Variant ID Type Subtype PubMed ID
nsv898952 CNV Loss 21882294
nsv525100 CNV Loss 19592680
nsv527807 CNV Loss 19592680
nsv469190 CNV Gain 19166990

Relevant External Links for OVCH1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OVCH1 Gene

Disorders for OVCH1 Gene

Relevant External Links for OVCH1

Genetic Association Database (GAD)

No disorders were found for OVCH1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OVCH1 Gene

Publications for OVCH1 Gene

  1. Human and mouse proteases: a comparative genomic approach. (PMID: 12838346) Puente X.S. … Lopez-Otin C. (Nat. Rev. Genet. 2003) 2 3 4
  2. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 3 4
  3. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PMID: 17903299) Kathiresan S. … Cupples L.A. (BMC Med. Genet. 2007) 48

Products for OVCH1 Gene

Sources for OVCH1 Gene

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