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Aliases for OTX2-AS1 Gene

Subcategory (RNA class) for OTX2-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

3

Aliases for OTX2-AS1 Gene

  • OTX2 Antisense RNA 1 (Head To Head) 2 3 5
  • OTX2 Antisense RNA 1 (Non-Protein Coding) 2 3
  • Otx2 Opposite Strand Transcript 1 3
  • OTX2 Antisense RNA 1 2
  • OTX2OS1 3

External Ids for OTX2-AS1 Gene

Previous GeneCards Identifiers for OTX2-AS1 Gene

  • GC14P057280

Summaries for OTX2-AS1 Gene

GeneCards Summary for OTX2-AS1 Gene

OTX2-AS1 (OTX2 Antisense RNA 1 (Head To Head)) is an RNA Gene, and is affiliated with the non-coding RNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OTX2-AS1 Gene

Genomics for OTX2-AS1 Gene

Regulatory Elements for OTX2-AS1 Gene

Enhancers for OTX2-AS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G056812 0.6 ENCODE 0.7 -1.8 -1806 0.2 RNF2 SUZ12 CHD1 CBX2 CTBP2 CHD7 EZH2 OTX2 OTX2-AS1
GH14G056813 0.6 ENCODE 0.7 -2.1 -2096 0.1 RNF2 SUZ12 CHD1 CBX2 CTBP2 CHD7 EZH2 OTX2 OTX2-AS1
GH14G056811 0.5 ENCODE 0.7 -1.2 -1176 0.1 SUZ12 CBX2 CTBP2 EZH2 OTX2-AS1 OTX2
GH14G056817 0.5 ENCODE 0.7 +4.6 4605 0.1 SUZ12 CBX2 CTBP2 OTX2-AS1 RN7SL461P
GH14G056815 0.5 FANTOM5 0.7 +2.3 2281 0.3 CBX8 CBX2 OTX2 OTX2-AS1 RN7SL461P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OTX2-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OTX2-AS1 Gene

Chromosome:
14
Start:
56,813,183 bp from pter
End:
57,152,177 bp from pter
Size:
338,995 bases
Orientation:
Plus strand

Genomic View for OTX2-AS1 Gene

Genes around OTX2-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OTX2-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OTX2-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OTX2-AS1 Gene

Proteins for OTX2-AS1 Gene

Post-translational modifications for OTX2-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for OTX2-AS1 Gene

Domains & Families for OTX2-AS1 Gene

Gene Families for OTX2-AS1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OTX2-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for OTX2-AS1 Gene

Function for OTX2-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OTX2-AS1 Gene

Localization for OTX2-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for OTX2-AS1 Gene

Pathways & Interactions for OTX2-AS1 Gene

SuperPathways for OTX2-AS1 Gene

No Data Available

Interacting Proteins for OTX2-AS1 Gene

Gene Ontology (GO) - Biological Process for OTX2-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for OTX2-AS1 Gene

Drugs & Compounds for OTX2-AS1 Gene

No Compound Related Data Available

Transcripts for OTX2-AS1 Gene

mRNA/cDNA for OTX2-AS1 Gene

(6) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OTX2-AS1 Gene

OTX2 antisense RNA 1 (head to head):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OTX2-AS1 Gene

No ASD Table

Relevant External Links for OTX2-AS1 Gene

GeneLoc Exon Structure for
OTX2-AS1
ECgene alternative splicing isoforms for
OTX2-AS1

Expression for OTX2-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OTX2-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for OTX2-AS1 Gene

This gene is overexpressed in Brain - Substantia nigra (x19.2), Brain - Hypothalamus (x8.1), Brain - Hippocampus (x6.4), and Brain - Caudate (basal ganglia) (x4.6).

SOURCE GeneReport for Unigene cluster for OTX2-AS1 Gene:

Hs.637962
genes like me logo Genes that share expression patterns with OTX2-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for OTX2-AS1 Gene

Orthologs for OTX2-AS1 Gene

Evolution for OTX2-AS1 Gene

ENSEMBL:
Gene Tree for OTX2-AS1 (if available)
TreeFam:
Gene Tree for OTX2-AS1 (if available)

No data available for Orthologs for OTX2-AS1 Gene

Paralogs for OTX2-AS1 Gene

No data available for Paralogs for OTX2-AS1 Gene

Variants for OTX2-AS1 Gene

Sequence variations from dbSNP and Humsavar for OTX2-AS1 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000008045 -- 56,840,983(+) GTTAG(A/G)ATAGA intron-variant
rs1000021257 -- 56,866,184(+) CGTAT(C/G)TTTAT intron-variant
rs1000028561 -- 56,835,272(+) TGTCT(C/G)TAAAA intron-variant
rs1000046912 -- 56,918,101(+) TGACA(A/G)GAGGC intron-variant
rs1000066722 -- 56,887,968(+) ATCCT(C/T)GAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OTX2-AS1 Gene

Variant ID Type Subtype PubMed ID
esv3581211 CNV loss 25503493
esv3581212 CNV loss 25503493
nsv1048136 CNV gain 25217958
nsv1288 CNV deletion 18451855
nsv507751 OTHER sequence alteration 20534489
nsv510381 OTHER sequence alteration 20534489
nsv519759 CNV loss 19592680
nsv564877 CNV gain 21841781

Relevant External Links for OTX2-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OTX2-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OTX2-AS1 Gene

Disorders for OTX2-AS1 Gene

Relevant External Links for OTX2-AS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OTX2-AS1

No disorders were found for OTX2-AS1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OTX2-AS1 Gene

Publications for OTX2-AS1 Gene

  1. Natural antisense transcripts associated with genes involved in eye development. (PMID: 15703187) Alfano G. … Banfi S. (Hum. Mol. Genet. 2005) 2 3 64
  2. Genetic risk variants for metabolic traits in Arab populations. (PMID: 28106113) Hebbar P. … Alsmadi O. (Sci Rep 2017) 3 64
  3. Methylation status of NEUROG2 and NID2 improves the diagnosis of stage I NSCLC. (PMID: 22741015) Geng J. … Yu J. (Oncol Lett 2012) 3 64
  4. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PMID: 21697133) Oshikawa M. … Kato S. (Invest. Ophthalmol. Vis. Sci. 2011) 3 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OTX2-AS1 Gene

Sources for OTX2-AS1 Gene

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