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OTUD7A Gene

protein-coding   GIFtS: 50
GCID: GC15M031773

OTU Deubiquitinase 7A

(Previous names: chromosome 15 open reading frame 16, OTU domain containing...)
(Previous symbols: C15orf16, OTUD7)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
OTU Deubiquitinase 7A1 2     OTU Domain Containing 71
OTUD71 2 3 5     C16ORF152
C15orf161 2 3     Cezanne 22
CEZANNE22 3 5     OTU Domain-Containing Protein 7A2
OTU Domain Containing 7A1 2     EC 3.4.19.123
Zinc Finger Protein Cezanne 22 3     C16orf155
Chromosome 15 Open Reading Frame 161     

External Ids:    HGNC: 207181   Entrez Gene: 1617252   Ensembl: ENSG000001699187   OMIM: 6120245   UniProtKB: Q8TE493   

Export aliases for OTUD7A gene to outside databases

Previous GC identifers: GC15M029564 GC15M008953


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for OTUD7A Gene:
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339)
linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian
tumor (OTU) domain.(supplied by OMIM, May 2008)

GeneCards Summary for OTUD7A Gene:
OTUD7A (OTU deubiquitinase 7A) is a protein-coding gene. GO annotations related to this gene include ubiquitin-specific protease activity. An important paralog of this gene is TNFAIP3.

UniProtKB/Swiss-Prot: OTU7A_HUMAN, Q8TE49
Function: Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NT_010194.18  NC_018926.2  NT_187660.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the OTUD7A gene promoter:
         ER-alpha   HOXA3   CUTL1   Meis-1b   C/EBPalpha   Nkx6-1   POU2F1   POU2F1a   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOTUD7A promoter sequence
   Search Chromatin IP Primers for OTUD7A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OTUD7A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q13.3   Ensembl cytogenetic band:  15q13.3   HGNC cytogenetic band: 15q13.1

OTUD7A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OTUD7A gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M031773:  view genomic region     (about GC identifiers)

Start:
31,775,329 bp from pter      End:
32,162,992 bp from pter
Size:
387,664 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: OTU7A_HUMAN, Q8TE49 (See protein sequence)
Recommended Name: OTU domain-containing protein 7A  
Size: 926 amino acids; 100677 Da
1 PDB 3D structure from and Proteopedia for OTUD7A:
2L2D (3D)    
Secondary accessions: Q8IWK5
Alternative splicing: 2 isoforms:  Q8TE49-1   Q8TE49-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for OTUD7A: NX_Q8TE49

Explore proteomics data for OTUD7A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See OTUD7A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_570971.1  
    ENSEMBL proteins: 
     ENSP00000305926   ENSP00000453622   ENSP00000453883   ENSP00000372358  

    OTUD7A Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for OTUD7A

     
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    antibodies-online proteins for OTUD7A (2 products) 

     
    antibodies-online peptides for OTUD7A

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    antibodies-online antibodies for OTUD7A (11 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    OTUD: OTU domain containing

    2 InterPro protein domains:
     IPR003323 OTU
     IPR002653 Znf_A20

    Graphical View of Domain Structure for InterPro Entry Q8TE49

    ProtoNet protein and cluster: Q8TE49

    UniProtKB/Swiss-Prot: OTU7A_HUMAN, Q8TE49
    Similarity: Belongs to the peptidase C64 family
    Similarity: Contains 1 A20-type zinc finger
    Similarity: Contains 1 OTU domain


    Find genes that share domains with OTUD7A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OTU7A_HUMAN, Q8TE49
    Function: Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains
    Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by
    the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

         Enzyme Number (IUBMB): EC 3.4.19.121

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0004843ubiquitin-specific protease activity IDA--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    Find genes that share ontologies with OTUD7A           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for OTUD7A

    miRNA
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    miRTarBase miRNAs that target OTUD7A:
    hsa-mir-30c-5p (MIRT047999)

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    5 qRT-PCR Assays for microRNAs that regulate OTUD7A:
    hsa-miR-3688-3p hsa-miR-593* hsa-miR-4302 hsa-miR-767-5p hsa-miR-888*
    SwitchGear 3'UTR luciferase reporter plasmidOTUD7A 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    OTU7A_HUMAN, Q8TE49: Cytoplasm (By similarity). Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with OTUD7A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OTUD7A
    Interactions:

        Search GeneGlobe Interaction Network for OTUD7A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for OTUD7A (Q8TE493 ENSP000003059264) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    VHLP403373, ENSP000002564744I2D: score=1 STRING: ENSP00000256474
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----
    GO:0035871protein K11-linked deubiquitination IDA--

    Find genes that share ontologies with OTUD7A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OTUD7A (OTU7A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OTUD7A gene: 
    NM_130901.1  

    Unigene Cluster for OTUD7A:

    OTU domain containing 7A
    Hs.355236  [show with all ESTs]
    Unigene Representative Sequence: CR749403
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000307050(uc001zfq.3) ENST00000560536(uc001zfs.1) ENST00000558371(uc010baa.1)
    ENST00000560598 ENST00000382902(uc001zfr.3)
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate OTUD7A:
    hsa-miR-3688-3p hsa-miR-593* hsa-miR-4302 hsa-miR-767-5p hsa-miR-888*
    SwitchGear 3'UTR luciferase reporter plasmidOTUD7A 3' UTR sequence
    Inhib. RNA
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      QuantiFast Probe-based Assays in human, mouse, rat OTUD7A

    Additional mRNA sequence: 

    AJ430383.1 AK126002.1 AK308630.1 BC035668.1 CR749403.1 

    6 DOTS entries:

    DT.97799283  DT.101957631  DT.97830618  DT.97830616  DT.106357  DT.92032272 

    8 AceView cDNA sequences:

    AJ430383 NM_130901 AI271697 BM546622 BQ068356 AK126002 BC035668 BF955468 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for OTUD7A    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:        -           -                 -                                                         
    SP2:                    -                 -                 -                                       
    SP3:        -                                                                                       


    ECgene alternative splicing isoforms for OTUD7A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OTUD7A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCTGGTCCA
    OTUD7A Expression
    About this image


    OTUD7A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Epithelial Cells
             Fetal Matrix Cells Hair Follicle
     
     Hair (Integumentary System)
             Fetal Matrix Cells Hair Follicle
    OTUD7A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OTUD7A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.355236
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for OTUD7A gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Otud7a1 , 5 OTU domain containing 7A1, 5 88.37(n)1
    94.44(a)1
      7 (34.52 cM)5
    1707111  NM_130880.11  NP_570950.11 
     634447515 
    chicken
    (Gallus gallus)
    Aves OTUD7A1 OTU domain containing 7A 71.77(n)
    81.52(a)
      415380  XM_004943755.1  XP_004943812.1 
    lizard
    (Anolis carolinensis)
    Reptilia OTUD7A6
    OTU domain containing 7A
    78(a)
    1 ↔ 1
    GL343428.1(199656-225683)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.204002 Transcribed sequence with moderate similarity to protein more 76.37(n)    AL862526.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5594551 OTU domain-containing protein 7A-like 71.64(n)
    76.53(a)
      559455  XM_003201466.2  XP_003201514.2 
    worm
    (Caenorhabditis elegans)
    Secernentea otub-26
    Protein OTUB-2 (otub-2) mRNA, complete cds
    32(a)
    1 → many
    I(398891-412847) WBGene00021733


    ENSEMBL Gene Tree for OTUD7A (if available)
    TreeFam Gene Tree for OTUD7A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OTUD7A gene
    TNFAIP32  OTUD7B2  ZRANB12  
    2 SIMAP similar genes for OTUD7A using alignment to 3 protein entries:     OTU7A_HUMAN (see all proteins):
    MGC131512    OTUD7B

    Find genes that share paralogs with OTUD7A           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for OTUD7A
    PGOHUM00000258946


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OTUD7A (see all 3660)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs711108841,2
    C--8973329(+) AGTCT-/TTAACAC 1 -- int11Minor allele frequency- TT:0.00NA 2
    rs669942151,2
    C--9005115(+) TTTTG-/T/TT  
            
    TTTTT
    1 -- int11NA 2
    rs1808135321,2
    --31774898(+) AGGAGA/GTTTTG 1 -- ds50010--------
    rs1845518041,2
    --31775064(+) AAGCCA/CTGGGT 1 -- ds50010--------
    rs58116461,2
    C--31775127(+) AGGAGA/-AAAAA 1 -- ds50011Minor allele frequency- -:0.00NA 2
    rs1386273191,2
    --31775174(+) TAAAAC/GAAAGG 1 -- ds50010--------
    rs1428676761,2
    --31775183(+) GGGCTA/GCGAAT 1 -- ds50010--------
    rs1137237961,2
    C,F--31775209(+) ACTGAG/AGAACA 1 -- ds50012Minor allele frequency- A:0.04NA WA 120
    rs615143821,2
    C,F--31775225(+) ACTCTT/GGCAAT 1 -- ds50012Minor allele frequency- G:0.06WA 120
    rs1474432011,2
    --31775226(+) CTCTTC/GCAATG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for OTUD7A (31775329 - 32025329 bp, first 250kb of OTUD7A)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for OTUD7A (see all 31):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2749534CNV Deletion23290073
    dgv337e201CNV Deletion23290073
    esv2749529CNV Deletion23290073
    esv2665812CNV Deletion23128226
    esv1355532CNV Deletion17803354
    esv1513730CNV Deletion17803354
    esv2749528CNV Deletion23290073
    esv2184065CNV Deletion18987734
    esv2749532CNV Deletion23290073
    esv2565352CNV Deletion19546169

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing OTUD7A
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612024    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for OTUD7A:
    Congenital stationary night blindness

    Find genes that share disorders with OTUD7A           About GenesLikeMe

    Genetic Association Database (GAD): OTUD7A
    Human Genome Epidemiology (HuGE) Navigator: OTUD7A (1 document)

    Export disorders for OTUD7A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OTUD7A gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with OTUD7A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. (PubMed id 23827681)1, 2, 3 Mevissen T.E.... Komander D. (Cell 2013)
    2. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. (PubMed id 20400778)1, 4 Morrison A.C....Smith N.L. (Circ Cardiovasc Genet 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. (PubMed id 23650146)1 Tang W....Smith N.L. (Genet. Epidemiol. 2013)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne. (PubMed id 20622874)2 Bremm A.... Komander D. (Nat. Struct. Mol. Biol. 2010)
    7. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    8. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 161725 HGNC: 20718 AceView: C15orf16 Ensembl:ENSG00000169918 euGenes: HUgn161725
    ECgene: OTUD7A H-InvDB: OTUD7A

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OTUD7A Pharmacogenomics, SNPs, Pathways

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    Patent Information for OTUD7A gene:
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