Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



OTUD6A Gene

protein-coding   GIFtS: 40
GCID: GC0XP069282

OTU Deubiquitinase 6A

(Previous name: OTU domain containing 6A)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
OTU Deubiquitinase 6A1 2     HSHIN62
DUBA22 3 5     HIN-6 Protease2
OTU Domain Containing 6A1 2     OTU Domain-Containing Protein 6A2
DUBA-22 3     EC 3.4.19.123

External Ids:    HGNC: 323121   Entrez Gene: 1395622   Ensembl: ENSG000001894017   OMIM: 3007145   UniProtKB: Q7L8S53   

Export aliases for OTUD6A gene to outside databases

Previous GC identifers: GC0XP069066 GC0XP069199 GC0XP063103


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for OTUD6A Gene:
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339)
linkages, negating the action of ubiquitin ligases. DUBA2 belongs to a DUB subfamily characterized by an ovarian
tumor (OTU) domain.(supplied by OMIM, May 2008)

GeneCards Summary for OTUD6A Gene:
OTUD6A (OTU deubiquitinase 6A) is a protein-coding gene. GO annotations related to this gene include ubiquitin-specific protease activity. An important paralog of this gene is OTUD6B.

UniProtKB/Swiss-Prot: OTU6A_HUMAN, Q7L8S5
Function: Deubiquitinating enzyme that hydrolyzes 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.
Also able to hydrolyze 'Lys-11'-linked ubiquitin chains




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NC_018934.2  NT_011651.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the OTUD6A gene promoter:
         RREB-1   COUP   HNF-4alpha2   NF-AT   HNF-4alpha1   NF-AT4   NF-AT2   SEF-1 (1)   NF-AT3   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidOTUD6A promoter sequence
   Search Chromatin IP Primers for OTUD6A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OTUD6A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.1   Ensembl cytogenetic band:  Xq13.1   HGNC cytogenetic band: Xq13.1

OTUD6A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OTUD6A gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP069282:  view genomic region     (about GC identifiers)

Start:
69,282,341 bp from pter      End:
69,284,029 bp from pter
Size:
1,689 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: OTU6A_HUMAN, Q7L8S5 (See protein sequence)
Recommended Name: OTU domain-containing protein 6A  
Size: 288 amino acids; 33300 Da
Secondary accessions: B2RPB7

Explore the universe of human proteins at neXtProt for OTUD6A: NX_Q7L8S5

Explore proteomics data for OTUD6A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See OTUD6A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_997203.1  
    ENSEMBL proteins: 
     ENSP00000339389  

    OTUD6A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for OTUD6A
    OriGene Custom MassSpec
    OriGene Custom Protein Services for OTUD6A
    GenScript Custom Purified and Recombinant Proteins Services for OTUD6A
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OTUD6A

     
    Search eBioscience for Proteins for OTUD6A 

     
    Search antibodies-online for proteins for OTUD6A 

     
    antibodies-online peptides for OTUD6A

    OTUD6A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for OTUD6A
    Novus Biologicals OTUD6A Antibodies
    Abcam antibodies for OTUD6A
    Cloud-Clone Corp. Antibodies for OTUD6A
    Search ThermoFisher Antibodies for OTUD6A
    antibodies-online antibodies for OTUD6A (16 products) 

    OTUD6A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for OTUD6A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for OTUD6A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for OTUD6A
    Cloud-Clone Corp. CLIAs for OTUD6A
    Search eBioscience for ELISAs for OTUD6A 
    antibodies-online kits for OTUD6A (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    OTUD: OTU domain containing

    1 InterPro protein domain:
     IPR003323 OTU

    Graphical View of Domain Structure for InterPro Entry Q7L8S5

    ProtoNet protein and cluster: Q7L8S5

    UniProtKB/Swiss-Prot: OTU6A_HUMAN, Q7L8S5
    Similarity: Contains 1 OTU domain


    Find genes that share domains with OTUD6A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OTU6A_HUMAN, Q7L8S5
    Function: Deubiquitinating enzyme that hydrolyzes 'Lys-27'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitin chains.
    Also able to hydrolyze 'Lys-11'-linked ubiquitin chains
    Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by
    the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

         Enzyme Number (IUBMB): EC 3.4.19.121

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004843ubiquitin-specific protease activity IDA--
         
    Find genes that share ontologies with OTUD6A           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for OTUD6A

    miRNA
    Products:
        
    miRTarBase miRNAs that target OTUD6A:
    hsa-mir-92a-3p (MIRT049350)

    Block miRNA regulation of human, mouse, rat OTUD6A using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate OTUD6A:
    hsa-miR-24-2* hsa-miR-3150b-3p hsa-miR-24-1*
    SwitchGear 3'UTR luciferase reporter plasmidOTUD6A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for OTUD6A
    Predesigned siRNA for gene silencing in human, mouse, rat OTUD6A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for OTUD6A

    Clone
    Products:
         
    OriGene clones in human, mouse for OTUD6A (see all 5)
    OriGene ORF clones in mouse, rat for OTUD6A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OTUD6A (NM_207320)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OTUD6A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTUD6A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for OTUD6A
    Browse ESI BIO Cell Lines and PureStem Progenitors for OTUD6A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTUD6A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OTUD6A
    Interactions:

        Search GeneGlobe Interaction Network for OTUD6A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for OTUD6A (ENSP000003393894) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PLAAENSP000003804604STRING: ENSP00000380460
    NSFL1CENSP000002168794STRING: ENSP00000216879
    UBXN2BENSP000003825074STRING: ENSP00000382507
    STUB1ENSP000002195484STRING: ENSP00000219548
    UBE4AENSP000002521084STRING: ENSP00000252108
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006508proteolysis ----
    GO:0035523protein K29-linked deubiquitination IDA--
    GO:0035871protein K11-linked deubiquitination IDA--
    GO:1990167protein K27-linked deubiquitination IDA--
    GO:1990168protein K33-linked deubiquitination IDA--

    Find genes that share ontologies with OTUD6A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OTUD6A (OTU6A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for OTUD6A gene: 
    NM_207320.1  

    Unigene Cluster for OTUD6A:

    OTU domain containing 6A
    Hs.447381
    Unigene Representative Sequence: NM_207320
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000338352(uc004dxu.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat OTUD6A using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate OTUD6A:
    hsa-miR-24-2* hsa-miR-3150b-3p hsa-miR-24-1*
    SwitchGear 3'UTR luciferase reporter plasmidOTUD6A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for OTUD6A
    Predesigned siRNA for gene silencing in human, mouse, rat OTUD6A
    Clone
    Products:
         
    OriGene clones in human, mouse for OTUD6A (see all 5)
    OriGene ORF clones in mouse, rat for OTUD6A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OTUD6A (NM_207320)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OTUD6A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTUD6A
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for OTUD6A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OTUD6A
      QuantiTect SYBR Green Assays in human, mouse, rat OTUD6A
      QuantiFast Probe-based Assays in human, mouse, rat OTUD6A

    Additional mRNA sequence: 

    AK098697.1 BC137355.1 BC137356.1 

    1 DOTS entry:

    DT.99927667 

    2 AceView cDNA sequences:

    NM_207320 AK098697 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    OTUD6A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGACAGCG
    OTUD6A Expression
    About this image

    OTUD6A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OTUD6A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.447381
        Custom PCR Arrays for OTUD6A
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for OTUD6A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OTUD6A
    QuantiTect SYBR Green Assays in human, mouse, rat OTUD6A
    QuantiFast Probe-based Assays in human, mouse, rat OTUD6A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTUD6A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for OTUD6A gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Otud6a1 , 5 OTU domain containing 6A1, 5 71.08(n)1
    64.11(a)1
      X (43.72 cM)5
    4081931  NM_001163191.11  NP_001156663.11 
     1004290135 
    chicken
    (Gallus gallus)
    Aves OTUD6B6
    Gallus gallus OTU domain containing 6B (OTUD6B), m...
    48(a)
    1 → many
    2(124553226-124562061)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    43(a)
    1 → many
    4(17344005-17356287)
    zebrafish
    (Danio rerio)
    Actinopterygii otud6b6
    OTU domain containing 6B
    45(a)
    1 → many
    19(35201113-35266742) ENSDARG00000022675
    fruit fly
    (Drosophila melanogaster)
    Insecta CG78576
    --
    32(a)
    1 → many
    3L(15496700-15497994)
    worm
    (Caenorhabditis elegans)
    Secernentea otub-36
    Protein OTUB-3, isoform a
    23(a)
    1 → many
    IV(8728139-8730519) WBGene00009007
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes OTU26
    Protein of unknown function that may interact with...
    24(a)
    1 → many
    VIII(77430-78353) YHL013C
    wheat
    (Triticum aestivum)
    Liliopsida Ta.119462 Triticum aestivum transcribed sequence with weak similarity more 79.02(n)    BQ171123.1 


    ENSEMBL Gene Tree for OTUD6A (if available)
    TreeFam Gene Tree for OTUD6A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for OTUD6A gene
    OTUD6B2  
    1 SIMAP similar gene for OTUD6A using alignment to 1 protein entry:     OTU6A_HUMAN:
    OTUD6B

    Find genes that share paralogs with OTUD6A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for OTUD6A (see all 84)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1419162541,2
    C,Funtested163104024(+) CGCTCA/C/GAGGCC 2 K E mis11NA 3944
    rs1828452981,2
    --63101185(+) GGTGTA/GTGTAG 1 -- us2k10--------
    rs65253531,2
    C,F,A,H--63101228(+) ggatcA/Gcttga 1 -- us2k16Minor allele frequency- G:0.30NA WA CSA 10
    rs599237271,2
    C--63101272(+) GTGAAG/ACCCTG 1 -- us2k12Minor allele frequency- A:0.00NA 3
    rs1881697401,2
    --63101306(+) ATCCGA/GGTGTG 1 -- us2k10--------
    rs1471491341,2
    C--63101462(+) AGAAAA/GAAAAA 1 -- us2k10--------
    rs1927700311,2
    --63101569(+) GAAGGG/TCTGAG 1 -- us2k10--------
    rs732282161,2
    C--63101662(+) GCTATC/TTTGGC 1 -- us2k10--------
    rs1923084531,2
    --63102373(+) CAACAC/TGGCGA 1 -- us2k10--------
    rs1847438751,2
    --63102568(+) CCCCCC/GTCAAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for OTUD6A (69282341 - 69284029 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for OTUD6A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv6949CNV Insertion18451855
    esv1584074OTHER Inversion17803354

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing OTUD6A
    DNA2.0 Custom Variant and Variant Library Synthesis for OTUD6A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 300714    OMIM disorders: --


    Find genes that share disorders with OTUD6A           About GenesLikeMe


    Export disorders for OTUD6A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for OTUD6A gene integrated from 10 sources:
    (articles sorted by number of sources associating them with OTUD6A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. (PubMed id 23827681)1, 2, 3 Mevissen T.E.... Komander D. (Cell 2013)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15. (PubMed id 23105109)1 Hayes S.D....UrbAc S. (J. Biol. Chem. 2012)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 139562 HGNC: 32312 AceView: FLJ25831 Ensembl:ENSG00000189401 euGenes: HUgn139562
    ECgene: OTUD6A H-InvDB: OTUD6A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for OTUD6A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for OTUD6A gene:
    Search GeneIP for patents involving OTUD6A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for OTUD6A  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for OTUD6A  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for OTUD6A  
     OriGene qSTAR qPCR primer pairs in human, mouse for OTUD6A   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for OTUD6A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for OTUD6A   OriGene Custom Protein Services for OTUD6A  

     
     
     Block miRNA regulation of human, mouse, rat OTUD6A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing OTUD6A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OTUD6A Predesigned siRNA for gene silencing in human, mouse, rat OTUD6A
     QuantiFast Probe-based Assays in human, mouse, rat OTUD6A QuantiTect SYBR Green Assays in human, mouse, rat OTUD6A
     Custom PCR Arrays for OTUD6A Search Chromatin IP Primers for OTUD6A
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat OTUD6A  Search GeneGlobe Interaction Network for OTUD6A
     Regulatory tfbs in OTUD6A promoter
     GenScript Custom Purified and Recombinant Proteins Services for OTUD6A GenScript cDNA clones with any tag delivered in your preferred vector for OTUD6A
     GenScript Custom Assay Services for OTUD6A GenScript Custom overexpressing Cell Line Services for OTUD6A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for OTUD6A (OTU6A)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     OTUD6A antibodies
     Antibodies for OTUD6A
     See all of Abcam's Antibodies, Kits and Proteins for OTUD6A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for OTUD6A
     Antibodies for OTUD6A
     ELISAs for OTUD6A
     CLIAs for OTUD6A



     Browse ESI BIO Cell Lines and PureStem Progenitors for OTUD6A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTUD6A
     SwitchGear 3'UTR luciferase reporter plasmids for OTUD6A
     SwitchGear Promoter luciferase reporter plasmids for OTUD6A
     Search ThermoFisher Antibodies for OTUD6A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTUD6A
     Browse compounds at ApexBio
     Search Addgene for plasmids for OTUD6A
      Search eBioscience for proteins for OTUD6A
      Search eBioscience for elisas for OTUD6A
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for OTUD6A
     antibodies-online antibodies for OTUD6A (16 products)
     antibodies-online kits for OTUD6A (4 products)
     antibodies-online peptides for OTUD6A
      Search antibodies-online for proteins for OTUD6A
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      OTUD6A gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4