OTUD5 Gene
protein-coding GIFtS: 52
GCID: GC0XM048779
|
|
OTU domain containing 5
| |
Aliases
for OTUD5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| OTU Domain Containing 51 2 | | Deubiquinating Enzyme A2 | | DUBA1 2 3 5 | | OTU Domain-Containing Protein 52 | | Deubiquitinating Enzyme A2 3 | | EC 3.4.19.123 | | DKFZp761A0521 | | |
Export aliases for OTUD5 gene to outside databasesPrevious GC identifers: GC0XM048536 GC0XM048665 GC0XM046435 |
Summaries
for OTUD5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OTUD5:
This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domainconfers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependentinnate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein.Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of thetype I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have beendescribed. (provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: OTUD5_HUMAN, Q96G74Function: Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro)
|
Genomic Views
for OTUD5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_079573.4
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the OTUD5 gene promoter:
PPAR-gamma1 Nkx2-5 PPAR-gamma2 Pax-4a c-Ets-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for OTUD5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OTUD5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.23 HGNC cytogenetic band: Xp11.23OTUD5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM048779: view genomic region
(about GC identifiers)
Start:
|
48,779,301 bp from pter |
End:
|
48,815,648 bp from pter |
Size:
|
36,348 bases |
Orientation:
|
minus strand |
|
Proteins
for OTUD5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: OTUD5_HUMAN, Q96G74 (See
protein sequence)Recommended Name: OTU domain-containing protein 5 Size: 571 amino acids; 60626 Da
Subunit: Interacts with TRAF3
Sequence caution: Sequence=BAB14131.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=BAB15416.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
3 PDB 3D structures from  and Proteopedia  for OTUD5:3PFY (3D)
3TMO (3D)
3TMP (3D)
Secondary accessions: B4DGG7 Q4KMN9 Q8N6T5 Q9H650 Q9H9U0 Q9NT65Alternative splicing: 4 isoforms: Q96G74-1 Q96G74-2 Q96G74-4 Q96G74-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for OTUD5: NX_Q96G74
Post-translational modifications:
Phosphorylation at Ser-177 is required for deubiquitinating activity1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96G74
OTUD5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001129629.1 NP_001129630.1 NP_001129631.1 NP_060072.1
ENSEMBL proteins: ENSP00000390767 ENSP00000156084 ENSP00000365671 ENSP00000401629 ENSP00000379969 Reactome Protein details: Q96G74
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- |
OTUD5 for ontologies About GeneDecksing
OTUD5 Antibody Products:
Assay Products for OTUD5: |
Protein
Domains /
Families
for OTUD5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OTUD5 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96G74ProtoNet protein and cluster: Q96G74 1 Blocks protein family: IPB003323 OTU-like cysteine protease
UniProtKB/Swiss-Prot: OTUD5_HUMAN, Q96G74Similarity: Belongs to the peptidase C85 familySimilarity: Contains 1 OTU domain |
Function
for OTUD5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: OTUD5_HUMAN, Q96G74Function: Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro)Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by theC-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)Enzyme regulation: Inhibited by N-ethyl-maleimide (NEM)Induction: Up-regulated by bacterial lipopolysaccharide (LPS) in bone marrow-derived macrophagesEnzyme Number (IUBMB): EC 3.4.19.121
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OTUD5 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OTUD5 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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| |  | GenScript: all cDNA clones in your preferred vector (see all 4): OTUD5 (NM_001136157) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for OTUD5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTUD5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTUD5 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004843 | ubiquitin-specific protease activity |
IDA | -- |
OTUD5 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for OTUD5:
Animal Models:
1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Otud5):
OTUD5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for OTUD5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways | | | 2 | Immune System | | | 3 | Negative regulation of RIG-I/MDA5 signaling by TRIAD3A | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 
Reactome Pathways for OTUD5
1 
Kegg Pathway (Kegg details for OTUD5):
OTUD5 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OTUD5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 19)
5/23 Interacting proteins for OTUD5 (Q96G742, 3 ENSP000001560844) via UniProtKB, MINT, STRING, and/or I2D (see all 23)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
IEA | -- | | GO:0032480 | negative regulation of type I interferon production |
TAS | -- | | GO:0032496 | response to lipopolysaccharide |
IDA | -- | | GO:0045087 | innate immune response |
TAS | -- | | GO:0070536 | protein K63-linked deubiquitination |
IDA | -- |
OTUD5 for ontologies About GeneDecksing
|
Drugs & Compounds
for OTUD5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for OTUD5
Search CenterWatch for drugs/clinical trials and news about OTUD5
|
Transcripts
for OTUD5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for OTUD5 gene (4 alternative transcripts): NM_001136157.1 NM_001136158.1 NM_001136159.1 NM_017602.3 Unigene Cluster for OTUD5: OTU domain containing 5 Hs.496098 [show with all ESTs]Unigene Representative Sequence: NM_0176027 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000455452 ENST00000156084(uc004dlu.3 uc004dlv.3 uc011mmp.2)
ENST00000376488 ENST00000428668 ENST00000484499 ENST00000481142 ENST00000396743(uc004dlt.4)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OTUD5 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OTUD5 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 4): OTUD5 (NM_001136157) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for OTUD5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTUD5 |
Additional cDNA sequence: AK022612.1 AK026260.1 AK294590.1 AL137509.1 BC009917.2 BC011738.2 BC028225.1 BC098440.1 20 DOTS entries: DT.115522 DT.95209037 DT.92009691 DT.75179188 DT.121324275 DT.423718 DT.121324300 DT.92441247 DT.121324266 DT.92441252 DT.95160217 DT.99986692 DT.121324302 DT.86854749 DT.95138795 DT.95160207 DT.100762868 DT.121324272 DT.121324286 DT.95151542 24/305 AceView cDNA sequences (see all 305): AA736511 BQ671582 BM714234 AI497949 BE859080 BU681125 NM_017602 AW339581 BM720303 BX390952 CB266956 AW474411 BC028225 BI255063 AW016038 AA768028 BQ643871 BU623872 BM662398 BQ009623 BQ681851 BM806347 BQ680900 AL137509
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for OTUD5 (see all 6) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11 |
|---|
|
| SP1: | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | - | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for OTUD5
|
Expression
for OTUD5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OTUD5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See OTUD5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OTUD5
SOURCE GeneReport for Unigene cluster: Hs.496098
UniProtKB/Swiss-Prot: OTUD5_HUMAN, Q96G74Tissue specificity: Expressed in various tissues, including the liver and placenta, as well as in peripheral bloodleukocytes
SABiosciences Custom PCR Arrays for OTUD5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OTUD5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OTUD5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OTUD5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OTUD5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTUD5 |
Orthologs
for OTUD5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for OTUD5 gene from 8/22 species (see all 22) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Otud51 , 5 |
OTU domain containing 51, 5 |
90.4(n)1
98.23(a)1 |
|
X (3.54 cM)5
546441 NM_138604.21 NP_613070.21
78413645 |
lizard
(Anolis carolinensis) |
Reptilia |
OTUD56 |
-- |
90(a) |
1 ↔ 1 |
GL343326.1(1284172-1290080) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC535202 |
hypothetical protein MGC53520 |
77.2(n) |
|
BC046254.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
sibz30i22.12 |
sibz30i22.1 |
77.75(n) |
|
368486 CA470320.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG60916 |
-- |
24(a) |
1 ↔ 1 |
3L(11598536-11602540) |
worm
(Caenorhabditis elegans) |
Secernentea |
B0546.26 |
Protein B0546.2 |
33(a) |
1 ↔ 1 |
IV(3373391-3378129) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G273506 |
OTU-like cysteine type protease |
26(a) |
1 ↔ 1 |
2(11699549-11704272) |
rice
(Oryza sativa) |
Liliopsida |
-- |
OTU-like cysteine protease family protein, putativ... |
23(a) |
1 ↔ 1 |
4(20285965-20291159) |
ENSEMBL Gene Tree for OTUD5 (if available)
TreeFam Gene Tree for OTUD5 (if available) |
Paralogs
for OTUD5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for OTUD5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for OTUD5 (48779301 - 48815648 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for OTUD5
1 CNV: 7789 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OTUD5 |
|
Disorders
/ Diseases
for OTUD5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OTUD5 for disorders About GeneDecksing
OMIM gene information: 300713
OMIM disorders: --
1  disease for OTUD5: About MalaCardspneumonia
Export disorders for OTUD5 gene to outside databases
|
Publications
for OTUD5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for OTUD5 gene, integrated from 9 sources (see all 32):
(articles sorted by number of sources associating them with OTUD5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Phosphorylation-dependent activity of the deubiquitinase DUBA. (PubMed id 22245969)1, 2 Huang O.W.... Cochran A.G. (2012)
- DUBA: a deubiquitinase that regulates type I interferon production. (PubMed id 17991829)1, 2 Kayagaki N....Dixit V.M. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
- Activity-based chemical proteomics accelerates inhibi tor development for deubiquitylating enzymes. (PubMed id 22118674)1 Altun M....Kessler B.M. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- A data set of human endogenous protein ubiquitination sites. (PubMed id 20972266)1 Shi Y....Qin J. (2011)
|
External Searches for OTUD5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing OTUD5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OTUD5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OTUD5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for OTUD5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for OTUD5 gene:
Search GeneIP for patents involving OTUD5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OTUD5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for OTUD5 | | OriGene shRNA RFP for OTUD5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OTUD5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OTUD5 | | | OriGene Protein Over-expression Lysate for OTUD5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for OTUD5 | | OriGene 3'-UTR Clone for OTUD5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OTUD5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OTUD5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for OTUD5 | | OriGene Custom Protein Services for OTUD5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OTUD5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OTUD5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OTUD5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OTUD5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OTUD5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OTUD5 |
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| | | | Search Tocris compounds for OTUD5 |
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 | | | OTUD5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTUD5 |
|  |  |  | | | | ThermoFisher Antibodies for OTUD5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTUD5 |
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