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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

OTOR Gene

protein-coding GIFtS: 53
GCID: GC20P016729

otoraplin

Explore 3 diseases affiliated with
OTOR via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Otoraplin¹
FDP¹ ² ³
MIAL¹ ² ³
MIAL1¹ ²
Fibrocyte-Derived Protein² ³
Melanoma Inhibitory Activity-Like Protein² ³

External Ids:	HGNC: 8517¹	Entrez Gene: 56914²	Ensembl: ENSG00000125879⁷	OMIM: 606067⁵	UniProtKB: Q9NRC9³

Export aliases for OTOR gene to outside databases

Previous GC identifers: GC20P016717 GC20P016724 GC20P016677

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OTOR:

The protein encoded by this gene is secreted via the Golgi apparatus and may function in cartilage development and

maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be

associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene family. In addition,

alternate polyA sites exist for this gene. (provided by RefSeq, Jul 2008)

Gene Wiki entry for OTOR

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000020.10 NC_018931.1 NT_011387.8

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the OTOR gene promoter:
MEF-2A PPAR-gamma1 FOXF2 AP-1 FOXJ2 (long isoform) FOXJ2 aMEF-2 FOXL1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: OTOR promoter sequence

Search SABiosciences Chromatin IP Primers for OTOR

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OTOR

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p12.1-p11.23 Ensembl cytogenetic band: 20p12.1 HGNC cytogenetic band: 20p12.1-p11.23

OTOR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OTOR gene location

GeneLoc information about chromosome 20 GeneLoc Exon Structure

GeneLoc location for GC20P016729: view genomic region (about GC identifiers)

Start:	16,729,003 bp from pter	End:	16,750,707 bp from pter
Size:	21,705 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: OTOR_HUMAN, Q9NRC9 (See protein sequence)

Recommended Name: Otoraplin precursor

Size: 128 amino acids; 14332 Da

Subcellular location: Secreted (Potential)

Secondary accessions: D3DW22 Q3MIU6

Explore the universe of human proteins at neXtProt for OTOR: NX_Q9NRC9

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NRC9

OTOR Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_064542.1

ENSEMBL proteins:

ENSP00000246081

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Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--

OTOR for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

OTOR for domains About GeneDecksing

2 InterPro domains/families:

IPR001452 SH3_domain

IPR011511 SH3_2

Graphical View of Domain Structure for InterPro Entry Q9NRC9

ProtoNet protein and cluster: Q9NRC9

1 Blocks protein family: IPB001452 SH3 domain signature

UniProtKB/Swiss-Prot: OTOR_HUMAN, Q9NRC9

Similarity: Belongs to the MIA/OTOR family

Similarity: Contains 1 SH3 domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Phenotypes:
1 MGI phenotypic allele

for Otor (no phenotypes)

OTOR for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Otor^tm1Lex for OTOR

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for OTOR

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In Situ Assay
Products:

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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for OTOR

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001502	cartilage condensation	IEA	--
GO:0007605	sensory perception of sound	TAS	10873378

OTOR for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for OTOR
Search CenterWatch for drugs/clinical trials and news about OTOR

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
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About This Section

REFSEQ mRNAs for OTOR gene:

NM_020157.2

Unigene Cluster for OTOR:

Otoraplin

Hs.41119 [show with all ESTs]

Unigene Representative Sequence: NM_020157

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000246081(uc002wpj.3) ENST00000486129 ENST00000490148

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Additional cDNA sequence:

AF233261.1 AF243505.1 AJ242552.1 AY359082.1 BC101688.1 BC101690.1

4 DOTS entries:

DT.307722 DT.100844264 DT.92070627 DT.40239237

24/33 AceView cDNA sequences (see all 33):

CR624240 NM_020157 AJ242552 N68117 AF233261 N63222 N69775 BX418941

AY359082 AF243505 BE858557 BX444840 BI492218 BI495574 BI496734 AW022083

BX444839 BI495576 BI493008 N67179 H88081 BI493047 BI495573 AW022047

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for OTOR About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5a	·	5b
SP1:					-		-
SP2:

ECgene alternative splicing isoforms for OTOR

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

OTOR expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGTTTTCTA

About this image

OTOR expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

5 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Inner Nuclear Layer

Type1 Off Cone Bipolar Cells

Bipolar, Retina

Limb

Zeugopod

Mesenchymal Condensate Cells

Bone, Cartilage

Ovary

Ovary

Bone

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Sclerotome cells (Primary Cell)

Bone, Cartilage, Somite

See OTOR Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OTOR

SOURCE GeneReport for Unigene cluster: Hs.41119

UniProtKB/Swiss-Prot: OTOR_HUMAN, Q9NRC9

Tissue specificity: Highly expressed in cochlea

SABiosciences Custom PCR Arrays for OTOR

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for OTOR gene from 3/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	OTOR¹	otoraplin	72.58(n) 75(a)		395484 NM_204732.1 NP_990063.1
lizard (Anolis carolinensis)	Reptilia	OTOR⁶	--	76(a)	1 ↔ 1	1(127296921-127299327)
fruit fly (Drosophila melanogaster)	Insecta	Tango1⁶	Transport and Golgi organization 1	2(a)	1 → many	2L(6649388-6654574)

ENSEMBL Gene Tree for OTOR (if available)
TreeFam Gene Tree for OTOR (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for OTOR gene

MIA2² MIA²

4 SIMAP similar genes for OTOR using alignment to 1 protein entry: OTOR_HUMAN:

MIA MIA3 MIA2 CTAGE5

OTOR for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 20 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs6111268^1,2	H	--	16727248(+)	`CTTTAG/AGAcag`	1	--	us2k¹		4		NS EA	420
rs192664739^1,2		--	16727257(+)	`AGGTGC/TGGTGG`	1	--	us2k¹		0	--	--	--	--
rs149508056^1,2		--	16727458(+)	`CCTGGA/CGACAG`	1	--	us2k¹		0	--	--	--	--
rs6135873^1,2	C,F,A,H	--	16727808(+)	`TCACAC/TACACA`	1	--	us2k¹		10		NS EA NA CSA WA	718
rs6135874^1,2	C,F,A	--	16727809(+)	`CACACA/GCACAC`	1	--	us2k¹		6		NA CSA WA EA	364
rs184145578^1,2		--	16727810(+)	`ACACAA/CACACA`	1	--	us2k¹		0	--	--	--	--
rs6135875^1,2	C,F,A,H	--	16727859(+)	`TTACCC/AATTTA`	1	--	us2k¹		105		NS EA NA PA EU CA WA CSA	6083
rs1018424^1,2	C,F,O,A,H	--	16727996(-)	`ATGCCC/TTCTCC`	1	--	us2k¹		21		EA NA NS WA CSA	1078
rs187885251^1,2		--	16728004(+)	`CATCCG/TGAGAG`	1	--	us2k¹		0	--	--	--	--
rs3761294^1,2	C,F,A,H	--	16728029(-)	`ATCCAT/CTGCTT`	1	--	us2k¹		28		NS EA NA CSA WA	2910

HapMap Linkage Disequilibrium report for OTOR (16729003 - 16750707 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for OTOR
2 CNVs: 6069 6070
Human Gene Mutation Database (HGMD): OTOR

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OTOR

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OTOR for disorders           About GeneDecksing

OMIM gene information: 606067    OMIM disorders: --

3 diseases for OTOR:    About MalaCards

melanoma disseminated intravascular coagulation pulmonary embolism

1 Novoseek disease relationship for OTOR gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
melanoma	43	6	11161796 (2), 10873378 (1)

Human Genome Epidemiology (HuGE) Navigator: OTOR (2 documents)

Export disorders for OTOR gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for OTOR gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with OTOR)

Utopia: connect your pdf to the dynamic
world of online information

A novel conserved cochlear gene, OTOR: identification, expression analysis, and chromosomal mapping. (PubMed id 10873378)^{1, 2, 3, 9} Robertson N.G.... Morton C.C. (2000)
Identification and characterization of an inner ear-expressed human melanoma inhibitory activity (MIA)-like gene (MIAL) with a frequent polymorphism that abolishes translation. (PubMed id 11161796)^{1, 2, 9} Rendtorff N.D.... Tommerup N. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PubMed id 15340161)^{1, 2} Zhang Z. and Henzel W.J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)^{1, 2} Deloukas P....Rogers J. (2001)
Fdp, a new fibrocyte-derived protein related to MIA/CD-RAP, has an in vitro effect on the early differentiation of the inner ear mesenchyme. (PubMed id 10998416)^{1, 2} Cohen-Salmon M.... Petit C. (2000)
Investigation of genetic susceptibility factors for h uman longevity - A targeted nonsynonymous SNP study. (PubMed id 20800603)¹ Flachsbart F....Nebel A. (2010)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. (PubMed id 7829101)¹ Robertson N.G....Morton C.C. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 56914	HGNC: 8517	AceView: OTOR	Ensembl:ENSG00000125879	euGenes: HUgn56914
ECgene: OTOR	H-InvDB: OTOR

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for OTOR	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for OTOR	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for OTOR gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for OTOR gene:
Search GeneIP for patents involving OTOR

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


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	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for OTOR
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OTOR		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OTOR
	OriGene Protein Over-expression Lysate for OTOR		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for OTOR		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OTOR		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OTOR
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for OTOR		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for OTOR		OriGene Custom Protein Services for OTOR
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OTOR
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OTOR
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OTOR
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OTOR
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OTOR
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OTOR

	GenScript Purified and Recombinant Proteins for OTOR		GenScript cDNA clones with any tag delivered in your preferred vector for OTOR
	GenScript Custom Assay Services for OTOR		GenScript Superior Antibodies for OTOR
	GenScript Custom overexpressing Cell Line Services for OTOR		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in OTOR promoter
	Search Chromatin IP Primers for OTOR
	RT² qPCR Primer Assay in human, mouse, rat OTOR
	Search GNC Networks for OTOR
	SABiosciences Custom PCR Arrays for OTOR

Search Tocris compounds for OTOR

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	OTOR antibodies
	OTOR proteins
	OTOR lysates

	Antibodies for OTOR
	See all of Abcam's Antibodies, Kits and Proteins for OTOR
	Custom Antibody / Protein Production Service
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	Abcam protocols and scientific support

Recombinant Protein for OTOR

OTOR Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for OTOR

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTOR

	SwitchGear 3'UTR luciferase reporter plasmids for OTOR
	SwitchGear Promoter luciferase reporter plasmids for OTOR

ThermoFisher Antibodies for OTOR

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTOR

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for OTOR

Sirion Biotech Customized:

	stable knockdown cell line services for OTOR
	inducible knockdown cell line services for OTOR
	design and validation of potent shRNA sequences against OTOR
	adenovirus for potent knockdown of OTOR
	adenovirus for overexpression of OTOR
	stable overexpressing cell line services for OTOR
	inducible overexpressing cell line services for OTOR

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes OTOR gene at Home site.

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OTOR Gene

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Export list of displayed genes

OTOR Gene

otoraplin

Aliasesfor OTOR gene

Summariesfor OTOR gene

Genomic Viewsfor OTOR gene

Proteinsfor OTOR gene

Protein Domains /Familiesfor OTOR gene

Functionfor OTOR gene

Pathways & Interactionsfor OTOR gene

Drugs & Compoundsfor OTOR gene

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Orthologsfor OTOR gene

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Genome Databases showing OTOR gene

Other Databases showing OTOR gene

Specialized Databases showing OTOR gene

Intellectual Propertyfor OTOR gene

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View Random Gene

Aliases
for OTOR gene

Summaries
for OTOR gene

Genomic Views
for OTOR gene

Proteins
for OTOR gene

Protein Domains /
Families
for OTOR gene

Function
for OTOR gene

Pathways & Interactions
for OTOR gene

Drugs & Compounds
for OTOR gene

Transcripts
for OTOR gene

Expression
for OTOR gene

Orthologs
for OTOR gene

Paralogs
for OTOR gene

Genomic Variants
for OTOR gene

Disorders / Diseases
for OTOR gene

Publications
for OTOR gene

Intellectual Property
for OTOR gene

Products
for OTOR gene