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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OTOA Gene

protein-coding   GIFtS: 46
GCID: GC16P021689

Otoancorin

(Previous names: deafness, autosomal recessive 22)
(Previous symbol: DFNB22)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
otoancorin1 2
DFNB221 2 5
Cancer/Testis Antigen 1081 2
Deafness, Autosomal Recessive 221
CT1082

External Ids:    HGNC: 163781   Entrez Gene: 1461832   Ensembl: ENSG000001557197   OMIM: 6070385   UniProtKB: Q7RTW83   

Export aliases for OTOA gene to outside databases

Previous GC identifers: GC16P021150 GC16P021698 GC16P021656 GC16P021597 GC16P020071


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OTOA Gene:
The protein encoded by this gene is specifically expressed in the inner ear, and is located at the interface
between the apical surface of the inner ear sensory epithelia and their overlying acellular gels. It is prposed
that this protein is involved in the attachment of the inner ear acellular gels to the apical surface of the
underlying nonsensory cells. Mutations in this gene are associated with autosomal recessive deafness type 22
(DFNB22). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
(provided by RefSeq, Sep 2009)

GeneCards Summary for OTOA Gene: 
OTOA (otoancorin) is a protein-coding gene. Diseases associated with OTOA include dfnb22 nonsyndromic hearing loss and deafness, and papillary transitional carcinoma. An important paralog of this gene is STRC.

UniProtKB/Swiss-Prot: OTOAN_HUMAN, Q7RTW8
Function: May act as an adhesion molecule




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.2  NT_010393.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OTOA gene promoter:
         Pax-5   Pax-6   RREB-1   HSF1 (long)   CUTL1   GATA-1   HSF2   HSF1short   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): OTOA promoter sequence
   Search SABiosciences Chromatin IP Primers for OTOA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OTOA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12.2|16p12.2   Ensembl cytogenetic band:  16p12.2   HGNC cytogenetic band: 16p12.2

OTOA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OTOA gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P021689:  view genomic region     (about GC identifiers)

Start:
21,689,835 bp from pter      End:
21,772,050 bp from pter
Size:
82,216 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OTOAN_HUMAN, Q7RTW8 (See protein sequence)
Recommended Name: Otoancorin precursor  
Size: 1153 amino acids; 128533 Da
Subcellular location: Apical cell membrane; Lipid-anchor, GPI-anchor; Extracellular side (Probable). Secreted,
extracellular space, extracellular matrix (Probable). Note=At the interface between the apical surface of the
epithelia and the overlying acellular gel of the tectorial and otoconial membranes (By similarity)
Sequence caution: Sequence=AK057335; Type=Frameshift; Positions=1139;
Secondary accessions: A1L3A8 A2VDI0 B3KWU3 E9PF51 Q8NA86 Q96M76
Alternative splicing: 5 isoforms:  Q7RTW8-1   Q7RTW8-2   Q7RTW8-3   Q7RTW8-4   Q7RTW8-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for OTOA: NX_Q7RTW8

Explore proteomics data for OTOA at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q7RTW8

  • OTOA Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OTOA Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001155155.1  NP_653273.3  NP_733764.1  

    ENSEMBL proteins: 
     ENSP00000286149   ENSP00000373610   ENSP00000373608   ENSP00000373609  

    Human Recombinant Protein Products for OTOA: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for OTOA 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0016324apical plasma membrane IEA--
    GO:0031225anchored to membrane IEA--

    OTOA for ontologies           About GeneDecksing



    OTOA Antibody Products: 
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    Cloud-Clone Corp. CLIAs for OTOA


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR026663 Otoancorin
     IPR026664 Stereocilin_related

    Graphical View of Domain Structure for InterPro Entry Q7RTW8

    ProtoNet protein and cluster: Q7RTW8

    UniProtKB/Swiss-Prot: OTOAN_HUMAN, Q7RTW8
    Similarity: Belongs to the stereocilin family


    OTOA for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OTOAN_HUMAN, Q7RTW8
    Function: May act as an adhesion molecule

    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Otoa):

     hearing/vestibular/ear  nervous system 

    OTOA for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OTOA 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OTOA

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OTOA 
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    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OTOA
    1 QIAGEN miScript miRNA Assays for microRNA that regulate OTOA:
    hsa-miR-944
    SwitchGear 3'UTR luciferase reporter plasmidOTOA 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTOA


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OTOA

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007605sensory perception of sound IEA--

    OTOA for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OTOA (OTOAN)

    Search CenterWatch for drugs/clinical trials and news about OTOA / OTOAN

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OTOA gene (3 alternative transcripts): 
    NM_001161683.1  NM_144672.3  NM_170664.2  

    Unigene Cluster for OTOA:

    Otoancorin
    Hs.408336  [show with all ESTs]
    Unigene Representative Sequence: NM_144672
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000286149 ENST00000388958(uc002djh.3) ENST00000388956(uc010vbj.2)
    ENST00000388957(uc002dji.3) ENST00000569064 ENST00000563871(uc010vbk.2)
    ENST00000563506
    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate OTOA:
    hsa-miR-944
    SwitchGear 3'UTR luciferase reporter plasmidOTOA 3' UTR sequence
    Inhib. RNA
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OTOA
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OTOA
    Sirion Biotech Customized lentivirus for stable overexpression of OTOA 
                         Customized lentivirus expression plasmids for stable overexpression of OTOA 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OTOA
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OTOA

    Additional mRNA sequence: 

    AK093062.1 AK125840.1 AK302733.1 BC038458.1 BC129992.1 BC129993.1 

    6 DOTS entries:

    DT.100019525  DT.101982055  DT.100019526  DT.97817379  DT.99936814  DT.95358409 

    20 AceView cDNA sequences:

    AX747895 NM_144672 NM_170664 BK000099 AK125840 AK093062 BG177023 BI459722 
    BC040551 BC038458 BV176563 AI300783 BG216075 BI561486 BM455441 AK057335 
    BG105996 BG219824 AI867309 BG184449 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for OTOA    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22 ^ 23 ^ 24 ^ 25 ^
    SP1:                                      -     -                                         -                                                                     
    SP2:                                                                                      -                                                                     
    SP3:                                                                                            -                                                               
    SP4:                                                                                                                                                            

    ExUns: 26
    SP1:      
    SP2:      
    SP3:      
    SP4:      


    ECgene alternative splicing isoforms for OTOA

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OTOA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTAGAGACA
    OTOA Expression
    About this image


    See OTOA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OTOA

    SOURCE GeneReport for Unigene cluster: Hs.408336
        SABiosciences Custom PCR Arrays for OTOA
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OTOA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for OTOA gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Otoa1 , 5 otoancorin1, 5 81.4(n)1
    77.38(a)1
      7 (65.07 cM)5
    2461901  NM_139310.11  NP_647471.11 
     1210833225 
    chicken
    (Gallus gallus)
    Aves OTOA1 otoancorin 64.37(n)
    59.63(a)
      416624  XM_001234948.2  XP_001234949.2 
    lizard
    (Anolis carolinensis)
    Reptilia OTOA6
    Uncharacterized protein
    54(a)
    1 ↔ 1
    GL343507.1(41276-71152)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000070151 otoancorin-like 42.76(n)
    27.8(a)
      100007015  XM_001345550.3  XP_001345586.3 


    ENSEMBL Gene Tree for OTOA (if available)
    TreeFam Gene Tree for OTOA (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OTOA gene
    STRC2  

    OTOA for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for OTOA
    PGOHUM00000249020


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1666 SNPs in OTOA are shown (see all 1666)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs681841031,2
    C--20077828(+) TATTA-/TTA   
      TTATTT
    TTTAG
    2 -- int10--------
    rs30541881,2
    C--20099176(-) CTTTT-/CTGTTCT 3 -- int1 trp30--------
    rs3702441361,2
    C--20105764(+) AAAAA-/AAAAAA 3 -- int10--------
    rs20056151,2
    --20107382(-) GGAAGA/GAAGAA 3 -- int10--------
    rs28876211,2
    C--20107410(-) GAAAGA/GAAGGA 3 -- int11Minor allele frequency- G:0.00NA 2
    rs30541641,2
    C--20107446(-) agaga-/AAgaagg 3 -- int10--------
    rs58161591,2
    C--20107564(+) TTCCTC/TTCCCT 3 -- int1 trp31Minor allele frequency- T:0.00NA 2
    rs2018303351,2
    --20115142(+) AATAC-/AAAAAA 3 -- int10--------
    rs346435951,2
    C--20115157(+) ACCCCA/-AAAAA 3 -- int11Minor allele frequency- -:0.00NA 2
    rs679201121,2
    F--20115157(+) ACCCCC/AAAAAA 3 -- int11Minor allele frequency- A:0.50NA 4

    HapMap Linkage Disequilibrium report for OTOA (21689835 - 21772050 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/39 variations for OTOA (see all 39):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2714070CNV Deletion23290073
    nsv820589CNV Duplication20802225
    dgv48n16CNV Insertion17901297
    dgv348n27CNV Loss19166990
    dgv2n29CNV Loss16826518
    nsv471086CNV Loss18288195
    dgv2644n71CNV Loss21882294
    dgv116e55CNV Loss17911159
    dgv2642n71CNV Loss21882294
    esv2751552CNV Loss17911159


    Human Gene Mutation Database (HGMD): OTOA
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing OTOA
    DNA2.0 Custom Variant and Variant Library Synthesis for OTOA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607038   
    OMIM disorders: 607039  
    UniProtKB/Swiss-Prot: OTOAN_HUMAN, Q7RTW8
  • Deafness, autosomal recessive, 22 (DFNB22) [MIM:607039]: A form of non-syndromic sensorineural hearing
    loss. Sensorineural deafness results from damage to the neural receptors of the inner ear, the nerve pathways to
    the brain, or the area of the brain that receives sound information. Note=The disease is caused by mutations
    affecting the gene represented in this entry

  • 5 diseases for OTOA:    About MalaCards
    dfnb22 nonsyndromic hearing loss and deafness    papillary transitional carcinoma    deafness, autosomal recessive 22    nonsyndromic hearing loss and deafness, autosomal recessive
    sensorineural hearing loss

    1 disease from the University of Copenhagen DISEASES database for OTOA:
    Papillary transitional carcinoma

    OTOA for disorders           About GeneDecksing

    Genetic Association Database (GAD): OTOA
    Human Genome Epidemiology (HuGE) Navigator: OTOA (1 document)

    Export disorders for OTOA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OTOA gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with OTOA)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22. (PubMed id 11972037)1, 2, 3 Zwaenepoel I.... Petit C. (2002)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. Genome-wide analysis of cancer/testis gene expression . (PubMed id 19088187)1, 3 Hofmann O....Hide W. (2008)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Five novel loci for inherited hearing loss mapped by SNP-based homozygosity profiles in Palestinian families. (PubMed id 19888295)1, 9 Shahin H....Kanaan M. (2010)
    6. A genome-wide association study of sporadic ALS in a homogenous Irish population. (PubMed id 18057069)4 Cronin S....Hardiman O. (2008)
    7. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Deafness and Heredita ry Hearing Loss Overview (PubMed id 20301607)1 Smith R.J.H....Van Camp G. (1993)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 146183 HGNC: 16378 AceView: OTOA Ensembl:ENSG00000155719 euGenes: HUgn146183
    ECgene: OTOA H-InvDB: OTOA

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OTOA Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OTOA gene:
    Search GeneIP for patents involving OTOA

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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