External Ids for OSTN Gene
Previous GeneCards Identifiers for OSTN Gene
GeneCards Summary for OSTN Gene
OSTN (Osteocrin) is a Protein Coding gene. Diseases associated with OSTN include Acromesomelic Dysplasia. GO annotations related to this gene include receptor binding and hormone activity.
UniProtKB/Swiss-Prot for OSTN Gene
Hormone that acts as a regulator of dendritic growth in the developing cerebral cortex in response to sensory experience (PubMed:27830782). Induced in the brain following membrane depolarization and inhibits dendritic branching in neurons of the developing cortex (PubMed:27830782). Probably acts by binding to natriuretic peptide receptor NPR3/NPR-C, thereby preventing binding between NPR3/NPR-C and natriuretic peptides, leading to increase cGMP production (By similarity).