OSTM1 Gene
protein-coding GIFtS: 51
GCID: GC06M108409
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osteopetrosis associated transmembrane protein 1
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Aliases
for OSTM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Osteopetrosis Associated Transmembrane Protein 11 2 | | GIPN2 | | GL1 2 3 5 | | GAIP-Interacting Protein N Terminus2 | | Chloride Channel 7 Beta Subunit2 3 | | Grey-Lethal Osteopetrosis2 | | OPTB52 5 | | Osteopetrosis-Associated Transmembrane Protein 12 | | HSPC0191 | | |
Export aliases for OSTM1 gene to outside databasesPrevious GC identifers: GC06M108364 GC06M108470 GC06M105930 |
Summaries
for OSTM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OSTM1:
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependentproteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling(RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause theautosomal recessive, infantile malignant form of osteopetrosis. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: OSTM1_HUMAN, Q86WC4Function: Required for osteoclast and melanocyte maturation and function (By similarity)
Gene Wiki entry for OSTM1
|
Genomic Views
for OSTM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_025741.15
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for OSTM1
Other transcription factors
Search SABiosciences Chromatin IP Primers for OSTM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSTM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6q21 Ensembl cytogenetic band: 6q21 HGNC cytogenetic band: 6q21OSTM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M108409: view genomic region
(about GC identifiers)
Start:
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108,362,613 bp from pter |
End:
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108,487,058 bp from pter |
Size:
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124,446 bases |
Orientation:
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minus strand |
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Proteins
for OSTM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: OSTM1_HUMAN, Q86WC4 (See
protein sequence)Recommended Name: Osteopetrosis-associated transmembrane protein 1 precursor Size: 334 amino acids; 37257 Da
Subunit: Chloride channel 7 are heteromers of alpha (CLCN7) and beta (OSTM1) subunits
Subcellular location: Lysosome membrane; Single-pass type I membrane protein. Note=Requires CLCN7 to travel tolysosomes
Sequence caution: Sequence=AAD27000.1; Type=Frameshift; Positions=221;
Secondary accessions: E1P5E3 Q5R391 Q6PCA7 Q7RTW6 Q8NC29 Q8TC82 Q9Y2S9Explore the universe of human proteins at neXtProt for OSTM1: NX_Q86WC4
Post-translational modifications:
Undergoes proteolytic cleavage in the luminal domain, the cleaved fragments might be linked by disulfide bonds with theremnant of the protein (By similarity)1
Highly N-glycosylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q86WC4
OSTM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_054747.2
ENSEMBL proteins: ENSP00000193322 ENSP00000398556 Reactome Protein details: Q86WC4
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
OSTM1 for ontologies About GeneDecksing
OSTM1 Antibody Products:
Assay Products for OSTM1: |
Protein
Domains /
Families
for OSTM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OSTM1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q86WC4ProtoNet protein and cluster: Q86WC4 |
Function
for OSTM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: OSTM1_HUMAN, Q86WC4Function: Required for osteoclast and melanocyte maturation and function (By similarity)
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OSTM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OSTM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for OSTM1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSTM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSTM1 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
OSTM1 for ontologies About GeneDecksing
Animal Models:
10 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Ostm1):
OSTM1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for OSTM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Ion channel transport | | | 2 | SLC-mediated transmembrane transport | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for OSTM1
OSTM1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for OSTM1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 8)
5/9 Interacting proteins for OSTM1 (Q86WC43 ENSP000001933224) via UniProtKB, MINT, STRING, and/or I2D (see all 9)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0030316 | osteoclast differentiation |
IEA | -- |
OSTM1 for ontologies About GeneDecksing
|
Drugs & Compounds
for OSTM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for OSTM1
Search CenterWatch for drugs/clinical trials and news about OSTM1
|
Transcripts
for OSTM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for OSTM1 gene: NM_014028.3 Unigene Clusters for OSTM1: Osteopetrosis associated transmembrane protein 1 Hs.226780 [show with all ESTs], Hs.741218 [show with all ESTs]Unigene Representative Sequences: AJ420489, NM_0140287 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000193322(uc003psd.3) ENST00000492130(uc003pse.1) ENST00000472669
ENST00000477774 ENST00000440575 ENST00000467960 ENST00000492070
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OSTM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OSTM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: OSTM1 (NM_014028) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for OSTM1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSTM1 |
Additional cDNA sequence: AF077205.1 AF533891.1 AJ420572.1 AK075012.1 AK129854.1 AK314393.1 AY358795.1 BC010845.1 BC016376.1 BC059412.1 BC068581.1 8 DOTS entries: DT.99981162 DT.454388 DT.100782656 DT.92032824 DT.100782659 DT.121280136 DT.97779993 DT.121318609 24/225 AceView cDNA sequences (see all 225): AV728049 BK000461 BQ679023 BG413553 AA946706 AI580671 AA831459 AW475060 AA805628 H03451 BM723785 AK129854 H25802 N36527 AI423718 BQ001811 H25403 AI806735 Z44707 AI623374 AF533891 AA718983 AI759998 BQ889844
GeneLoc Exon Structure
|
Expression
for OSTM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OSTM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CCTGTGTTTG
About this image
See OSTM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OSTM1
SOURCE GeneReport for Unigene clusters: Hs.226780 Hs.741218
SABiosciences Expression via Pathway-Focused PCR Array including OSTM1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OSTM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OSTM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSTM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSTM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSTM1 |
Orthologs
for OSTM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for OSTM1 gene from 6/12 species (see all 12) About this table
ENSEMBL Gene Tree for OSTM1 (if available)
TreeFam Gene Tree for OSTM1 (if available) |
Paralogs
for OSTM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for OSTM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for OSTM1 (108362613 - 108487058 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for OSTM1
1 Indel: 59285
Human Gene Mutation Database (HGMD): OSTM1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OSTM1 |
|
Disorders
/ Diseases
for OSTM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OSTM1 for disorders About GeneDecksing
OMIM gene information: 607649
OMIM disorders: 259720
UniProtKB/Swiss-Prot: OSTM1_HUMAN, Q86WC4
Defects in OSTM1 are the cause of osteopetrosis autosomal recessive type 5 (OPTB5) [MIM:259720]; also calledinfantile malignant osteopetrosis 3. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone,due to defective resorption of immature bone. The disorder occurs in two forms: a severe autosomal recessive formoccurring in utero, infancy, or childhood, and a benign autosomal dominant form occurring in adolescence or adulthood.OPTB5 patients manifest primary central nervous system involvement in addition to the classical stigmata of severebone sclerosis, growth failure, anemia, thrombocytopenia and visual impairment with optic atrophy
8  diseases for OSTM1: About MalaCardsosteopetrosis osteopetrosis autosomal recessive 5 cleft lip/palate lysosomal storage disease
cleft lip optic atrophy nephrolithiasis kidney disease
1 disease from the University of Copenhagen DISEASES database for OSTM1:Osteopetrosis 2 Novoseek disease relationships for OSTM1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| osteopetrosis |
89.7 |
3 |
15177004 (2), 12627228 (1) |
| bone diseases |
64.7 |
1 |
15108279 (1) |
Human Genome Epidemiology (HuGE) Navigator: OSTM1 (4 documents)
Export disorders for OSTM1 gene to outside databases
|
Publications
for OSTM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for OSTM1 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with OSTM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Grey-lethal mutation induces severe malignant autosomal recessive osteopetrosis in mouse and human. (PubMed id 12627228)1, 2, 3, 9 Chalhoub N.... Vacher J. (2003)
- ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchange r and requires Ostm1 for transport activity. (PubMed id 21527911)1, 2, 3 Leisle L....Stauber T. (2011)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Novel vertebrate genes and putative regulatory elements identified at kidney disease and NR2E1/fierce loci. (PubMed id 12079282)1, 2 Abrahams B.S....Venkatesh B. (2002)
- Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2 Zhang Q.-H.... Chen Z. (2000)
- Severe malignant osteopetrosis caused by a GL gene mutation. (PubMed id 15177004)1, 9 Quarello P....Ramenghi U. (2004)
- Identification of a novel mutation in the coding region of the grey-lethal gene OSTM1 in human malignant infantile osteopetrosis. (PubMed id 15108279)1, 9 Ramirez A....Kubisch C. (2004)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
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External Searches for OSTM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing OSTM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OSTM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OSTM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for OSTM1 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/OSTM1 |
|
| | |
About This Section
| Patent Information for OSTM1 gene:
Search GeneIP for patents involving OSTM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OSTM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OSTM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OSTM1 | | | OriGene Protein Over-expression Lysate for OSTM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for OSTM1 | | OriGene 3'-UTR Clone for OSTM1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OSTM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OSTM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for OSTM1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for OSTM1 | | OriGene Custom Protein Services for OSTM1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OSTM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OSTM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSTM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSTM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSTM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSTM1 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSTM1 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSTM1 |
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