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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OSTC Gene

protein-coding   GIFtS: 48
GCID: GC04P109572

Oligosaccharyltransferase Complex Subunit (Non-Catalytic)

(Previous name: oligosaccharyltransferase complex subunit)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Oligosaccharyltransferase Complex Subunit (Non-Catalytic)1 2
Hydrophobic Protein HSF-282 3
DC2 Protein1
Oligosaccharyltransferase Complex Subunit1
Oligosaccharyltransferase Complex Subunit OSTC2

External Ids:    HGNC: 244481   Entrez Gene: 585052   Ensembl: ENSG000001988567   UniProtKB: Q9NRP03   

Export aliases for OSTC gene to outside databases

Previous GC identifers: GC04P109793 GC04P105303


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for OSTC Gene: 
OSTC (oligosaccharyltransferase complex subunit (non-catalytic)) is a protein-coding gene. Diseases associated with OSTC include alcohol dependence, and intrahepatic cholangiocarcinoma. GO annotations related to this gene include dolichyl-diphosphooligosaccharide-protein glycotransferase activity.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.2  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OSTC gene promoter:
         SRF   AML1a   SRF (504 AA)   XBP-1   Meis-1b   Egr-2   MZF-1   Zic1   Meis-1a   Meis-1   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for OSTC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSTC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q25   Ensembl cytogenetic band:  4q25   HGNC cytogenetic band: 4q25

OSTC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OSTC gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P109572:  view genomic region     (about GC identifiers)

Start:
109,571,740 bp from pter      End:
109,588,978 bp from pter
Size:
17,239 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OSTC_HUMAN, Q9NRP0 (See protein sequence)
Recommended Name: Oligosaccharyltransferase complex subunit OSTC  
Size: 149 amino acids; 16829 Da
Subunit: Component of the oligosaccharyltransferase (OST) complex. OST seems to exist in different forms which
contain at least RPN1, RPN2, OST48, DAD1, OSTC, KRTCAP2 and either STT3A or STT3B. OST can form stable complexes
with the Sec61 complex or with both the Sec61 and TRAP complexes (By similarity)
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Sequence caution: Sequence=AAF28985.1; Type=Erroneous initiation; Sequence=AAF65186.1; Type=Erroneous initiation;
Sequence=CN430159; Type=Frameshift; Positions=134;
Secondary accessions: A8MYS2 B2R5H1 D6RH22 Q9P075 Q9P1R4
Alternative splicing: 2 isoforms:  Q9NRP0-1   Q9NRP0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for OSTC: NX_Q9NRP0

Explore proteomics data for OSTC at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NRP0

  • OSTC Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OSTC Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001254746.1  NP_001254747.1  NP_067050.1  

    ENSEMBL proteins: 
     ENSP00000354676   ENSP00000426167  

    Human Recombinant Protein Products for OSTC: 
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    Novus Biologicals OSTC Protein
    Novus Biologicals OSTC Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OSTC 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008250oligosaccharyltransferase complex IDA15835887
    GO:0016021integral to membrane IEA--

    OSTC for ontologies           About GeneDecksing



    OSTC Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for OSTC 

    Assay Products for OSTC: 
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    Cloud-Clone Corp. ELISAs for OSTC 
    Cloud-Clone Corp. CLIAs for OSTC


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR021149 OligosaccharylTrfase_OST3/OST6

    Graphical View of Domain Structure for InterPro Entry Q9NRP0

    ProtoNet protein and cluster: Q9NRP0

    UniProtKB/Swiss-Prot: OSTC_HUMAN, Q9NRP0
    Similarity: Belongs to the OSTC family


    OSTC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004579contributes to dolichyl-diphosphooligosaccharide-protein glycotransferase activity IC15835887
         
    OSTC for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for OSTC:
     Increased S DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OSTC 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OSTC

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OSTC 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OSTC 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSTC
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate OSTC (see all 10):
    hsa-miR-320a hsa-miR-485-3p hsa-miR-29a hsa-miR-29c hsa-miR-320d hsa-miR-3692 hsa-miR-320b hsa-miR-330-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Clone
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    OriGene clones in human, mouse for OSTC (see all 7)
    OriGene ORF clones in mouse, rat for OSTC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OSTC (NM_021227)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OSTC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSTC
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                         Customized lentivirus expression plasmids for stable overexpression of OSTC 

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSTC


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OSTC

    STRING Interaction Network Preview (showing 5 interactants - click image to see 20)

    5/20 Interacting proteins for OSTC (Q9NRP03 ENSP000003546764) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TSC22D1Q157143, ENSP000003974354I2D: score=1 STRING: ENSP00000397435
    DAD1ENSP000002504984STRING: ENSP00000250498
    MAGT1ENSP000003546494STRING: ENSP00000354649
    RPN1ENSP000002962554STRING: ENSP00000296255
    RPN2ENSP000002375304STRING: ENSP00000237530
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0018279protein N-linked glycosylation via asparagine IC15835887

    OSTC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OSTC

    Search CenterWatch for drugs/clinical trials and news about OSTC

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OSTC gene (3 alternative transcripts): 
    NM_001267817.1  NM_001267818.1  NM_021227.3  

    Unigene Cluster for OSTC:

    Oligosaccharyltransferase complex subunit (non-catalytic)
    Hs.445803  [show with all ESTs]
    Unigene Representative Sequence: BF698884
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361564(uc003hzb.1) ENST00000510556 ENST00000505745 ENST00000512478

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSTC
    8/10 QIAGEN miScript miRNA Assays for microRNAs that regulate OSTC (see all 10):
    hsa-miR-320a hsa-miR-485-3p hsa-miR-29a hsa-miR-29c hsa-miR-320d hsa-miR-3692 hsa-miR-320b hsa-miR-330-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for OSTC
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSTC
    Clone
    Products:
         
    OriGene clones in human, mouse for OSTC (see all 7)
    OriGene ORF clones in mouse, rat for OSTC
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: OSTC (NM_021227)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OSTC
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSTC
    Sirion Biotech Customized lentivirus for stable overexpression of OSTC 
                         Customized lentivirus expression plasmids for stable overexpression of OSTC 
    Primer
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    OriGene qPCR primer pairs and template standards for OSTC
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSTC
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSTC

    Additional mRNA sequence: 

    AF068297.1 AF161425.1 AF201937.1 AF343342.1 AK312185.1 BC016321.1 BC054857.1 

    22 DOTS entries:

    DT.449886  DT.100693052  DT.100693017  DT.100874983  DT.100693010  DT.99994326  DT.100753275  DT.92467749 
    DT.92467759  DT.92467761  DT.92467775  DT.95269008  DT.121248087  DT.92020858  DT.92467758  DT.95269007 
    DT.95269022  DT.100767874  DT.121405124  DT.86855522  DT.92461139  DT.95192977 

    24/757 AceView cDNA sequences (see all 757):

    AW769410 AI147645 BM795103 CR596779 AI336035 BU616545 CR621571 BQ221843 
    W48638 BU615571 CA942851 AA490941 AW967190 AA369186 BE567837 BU607621 
    BM561622 BE379974 AA976910 BG546572 AW273470 BQ013984 AA099179 BF724501 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for OSTC    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b
    SP1:                                          
    SP2:                          -               
    SP3:              -                           


    ECgene alternative splicing isoforms for OSTC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OSTC expression in normal human tissues (normalized intensities)      OSTC embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAATGAAAC
    OSTC Expression
    About this image


    OSTC expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)
             Thoracic Rib
     
     Cartilage (Muscoskeletal System)
             Meckel's Cartilage
     
     Oral Cavity (Gastrointestinal Tract)
             salivary gland   

    See OSTC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OSTC

    SOURCE GeneReport for Unigene cluster: Hs.445803
        SABiosciences Custom PCR Arrays for OSTC
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSTC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for OSTC gene from 8/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ostc1 , 5 oligosaccharyltransferase complex subunit1, 5 89.71(n)1
    99.33(a)1
      3 (60.53 cM)5
    663571  NM_025509.31  NP_079785.11 
     1306959215 
    chicken
    (Gallus gallus)
    Aves OSTC1 oligosaccharyltransferase complex subunit 81.66(n)
    94.63(a)
      422525  NM_001006442.1  NP_001006442.1 
    lizard
    (Anolis carolinensis)
    Reptilia OSTC6
    Uncharacterized protein
    92(a)
    1 ↔ 1
    5(145076010-145082067)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.291282 Xenopus laevis transcribed sequence with strong similarity more 81.16(n)    48035333 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc565592 similar to DC2 protein 78.91(n)   393239  BC049047.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG96621 CG9662 60.5(n)
    63.01(a)
      33554  NM_134928.5  NP_608772.3 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G193401 Oligosaccharyltransferase complex/magnesium transporter more 52.62(n)
    47.14(a)
      816451  NM_179656.2  NP_849987.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g03154001 hypothetical protein 49.41(n)
    46.1(a)
      4329143  NM_001053198.1  NP_001046663.1 


    ENSEMBL Gene Tree for OSTC (if available)
    TreeFam Gene Tree for OSTC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OSTC gene
    1 SIMAP similar gene for OSTC using alignment to 1 protein entry:     OSTC_HUMAN:
    OSTCL

    OSTC for paralogs           About GeneDecksing


    5/9 Pseudogenes.org Pseudogenes for OSTC (see all 9)
    PGOHUM00000262983 PGOHUM00000234776 PGOHUM00000243945 PGOHUM00000244001 PGOHUM00000244692


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/424 SNPs in OSTC are shown (see all 424)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0392314
    A breast cancer sample4--see VAR_0392312 F L mis40--------
    rs1450968671,2
    --109569812(+) TGTGTC/TCTGAC 3 -- us2k10--------
    rs28513841,2
    C,F,A,H--109569824(-) TAAAAT/CTGCCA 3 -- us2k113Minor allele frequency- C:0.11NS EA NA WA CSA 782
    rs25756501,2
    C,F,H--109570062(+) AGGAGT/CCACTT 3 -- us2k117Minor allele frequency- C:0.12NA NS EA WA CSA 928
    rs1813222071,2
    --109570167(+) GCCAAG/TCAGTG 3 -- us2k10--------
    rs1843204901,2
    C--109570221(+) AAAAAC/TCTTTA 3 -- us2k10--------
    rs28513831,2
    C,F,O,A,H--109570461(-) TAACGC/GAGCCA 3 -- us2k120Minor allele frequency- G:0.15NA NS EA WA CSA 1001
    rs28513821,2
    C,F,O,A,H--109570589(-) AATTGT/CTTGAA 3 -- us2k125Minor allele frequency- C:0.13NA NS EA WA CSA 1531
    rs1509896311,2
    --109570683(+) AGCAAA/CTAAAA 3 -- us2k10--------
    rs1408456851,2
    --109570775(+) GGAAGC/TTAACA 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for OSTC (109571740 - 109588978 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for OSTC: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing OSTC
    DNA2.0 Custom Variant and Variant Library Synthesis for OSTC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    4 diseases for OSTC:    About MalaCards
    alcohol dependence    intrahepatic cholangiocarcinoma    cholangiocarcinoma    alcoholism


    OSTC for disorders           About GeneDecksing

    Genetic Association Database (GAD): OSTC
    Human Genome Epidemiology (HuGE) Navigator: OSTC (1 document)

    Export disorders for OSTC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OSTC gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with OSTC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1, 4 Kalsi G....Riley B.P. (2010)
    2. Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits. (PubMed id 15835887)1, 3 Shibatani T.... Skach W.R. (2005)
    3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PubMed id 15146197)1, 2 Brandenberger R.... Stanton L.W. (2004)
    4. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    5. Identification of novel ATP13A2 interactors and their role in a-synuclein misfolding and toxicity. (PubMed id 22645275)1 Usenovic M....Krainc D. (2012)
    6. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    10. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 58505 HGNC: 24448 AceView: DC2 Ensembl:ENSG00000198856 euGenes: HUgn58505
    ECgene: OSTC H-InvDB: OSTC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OSTC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OSTC gene:
    Search GeneIP for patents involving OSTC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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