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Aliases for OSR1 Gene

Aliases for OSR1 Gene

  • Odd-Skipped Related Transciption Factor 1 2 3
  • ODD 3 4
  • Odd-Skipped Related 1 (Drosophila) 2
  • Odd-Skipped (Drosophila) Homolog 2
  • Protein Odd-Skipped-Related 1 3
  • Odd-Skipped Related 1 3
  • Odd-Skipped Homolog 3
  • ODD, 6

External Ids for OSR1 Gene

Previous HGNC Symbols for OSR1 Gene

  • ODD

Previous GeneCards Identifiers for OSR1 Gene

  • GC03P037496
  • GC03P038020
  • GC03P038167
  • GC03P038182
  • GC02M019473
  • GC02M019308
  • GC02M019551

Summaries for OSR1 Gene

GeneCards Summary for OSR1 Gene

OSR1 (Odd-Skipped Related Transciption Factor 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding. An important paralog of this gene is OSR2.

UniProtKB/Swiss-Prot for OSR1 Gene

  • Transcription factor that plays a role in the regulation of embryonic heart and urogenital development.

Gene Wiki entry for OSR1 Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OSR1 Gene

Genomics for OSR1 Gene

Regulatory Elements for OSR1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for OSR1 Gene

19,351,485 bp from pter
19,358,653 bp from pter
7,169 bases
Minus strand

Genomic View for OSR1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OSR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OSR1 Gene

Proteins for OSR1 Gene

  • Protein details for OSR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein odd-skipped-related 1
    Protein Accession:
    Secondary Accessions:
    • B3KV97
    • D6W521

    Protein attributes for OSR1 Gene

    266 amino acids
    Molecular mass:
    29611 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OSR1 Gene

Proteomics data for OSR1 Gene at MOPED

Post-translational modifications for OSR1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OSR1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OSR1 Gene

Domains for OSR1 Gene

Gene Families for OSR1 Gene

  • ZNF :Zinc fingers, C2H2-type

Protein Domains for OSR1 Gene

Suggested Antigen Peptide Sequences for OSR1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q8TAX0
  • Belongs to the Odd C2H2-type zinc-finger protein family.
  • Contains 3 C2H2-type zinc fingers.
genes like me logo Genes that share domains with OSR1: view

Function for OSR1 Gene

Molecular function for OSR1 Gene

GENATLAS Biochemistry: oxidative-stress responsive 1,homolog to the human SOK1 (Ste20/oxidant stress response kinase-1),widely expressed
UniProtKB/Swiss-Prot Function: Transcription factor that plays a role in the regulation of embryonic heart and urogenital development.

Gene Ontology (GO) - Molecular Function for OSR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with OSR1: view
genes like me logo Genes that share phenotypes with OSR1: view

Animal Models for OSR1 Gene

MGI Knock Outs for OSR1:

Animal Model Products

CRISPR Products

miRNA for OSR1 Gene

miRTarBase miRNAs that target OSR1

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OSR1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targeting and HOMER Transcription for OSR1 Gene

Localization for OSR1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OSR1 Gene

Subcellular locations from

Jensen Localization Image for OSR1 Gene COMPARTMENTS Subcellular localization image for OSR1 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for OSR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA --
genes like me logo Genes that share ontologies with OSR1: view

Pathways for OSR1 Gene

SuperPathways for OSR1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for OSR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter ISS --
GO:0001655 urogenital system development ISS --
GO:0001656 metanephros development --
GO:0001657 ureteric bud development ISS --
GO:0001823 mesonephros development ISS --
genes like me logo Genes that share ontologies with OSR1: view

No data available for Pathways by source for OSR1 Gene

Transcripts for OSR1 Gene

mRNA/cDNA for OSR1 Gene

Unigene Clusters for OSR1 Gene

Odd-skipped related 1 (Drosophila):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OSR1

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OSR1 Gene

No ASD Table

Relevant External Links for OSR1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OSR1 Gene

mRNA expression in normal human tissues for OSR1 Gene

mRNA differential expression in normal tissues according to GTEx for OSR1 Gene

This gene is overexpressed in Artery - Aorta (7.6), Bladder (6.1), and Esophagus - Muscularis (4.1).

SOURCE GeneReport for Unigene cluster for OSR1 Gene Hs.123933

mRNA Expression by UniProt/SwissProt for OSR1 Gene

Tissue specificity: Expressed in adult colon, small intestine, prostate, testis, and fetal lung.
genes like me logo Genes that share expressions with OSR1: view

In Situ Assay Products

No data available for Protein expression for OSR1 Gene

Orthologs for OSR1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OSR1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia OSR1 35
  • 99.62 (n)
  • 99.62 (a)
OSR1 36
  • 100 (a)
(Bos Taurus)
Mammalia OSR1 35
  • 91.98 (n)
  • 98.87 (a)
OSR1 36
  • 79 (a)
(Canis familiaris)
Mammalia OSR1 35
  • 90.6 (n)
  • 96.99 (a)
OSR1 36
  • 93 (a)
(Mus musculus)
Mammalia Osr1 35
  • 89.85 (n)
  • 97.74 (a)
Osr1 16
Osr1 36
  • 98 (a)
(Monodelphis domestica)
Mammalia OSR1 36
  • 91 (a)
(Rattus norvegicus)
Mammalia Osr1 35
  • 90.6 (n)
  • 97.74 (a)
(Gallus gallus)
Aves OSR1 35
  • 77.95 (n)
  • 89.23 (a)
OSR1 36
  • 87 (a)
(Anolis carolinensis)
Reptilia OSR1 36
  • 91 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.13607 35
tropical clawed frog
(Silurana tropicalis)
Amphibia osr1 35
  • 74.26 (n)
  • 87.26 (a)
(Danio rerio)
Actinopterygii Dr.13499 35
osr1 35
  • 71.96 (n)
  • 79.84 (a)
osr1 36
  • 77 (a)
fruit fly
(Drosophila melanogaster)
Insecta bowl 36
  • 15 (a)
drm 36
  • 44 (a)
odd 36
  • 25 (a)
sob 36
  • 21 (a)
fray 37
  • 56 (a)
(Caenorhabditis elegans)
Secernentea odd-1 36
  • 34 (a)
odd-2 36
  • 36 (a)
Y59A8B.23 37
  • 63 (a)
Species with no ortholog for OSR1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for OSR1 Gene

Gene Tree for OSR1 (if available)
Gene Tree for OSR1 (if available)

Paralogs for OSR1 Gene

Paralogs for OSR1 Gene

Selected SIMAP similar genes for OSR1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OSR1: view

Variants for OSR1 Gene

Sequence variations from dbSNP and Humsavar for OSR1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs851066 -- 19,352,628(-) TAAAC(A/G)GGTGG intron-variant
rs3036446 -- 19,354,390(-) tgtgt(-/GTG)AGATT intron-variant
rs5013667 -- 19,357,830(+) GCGCA(A/G)CTCCT intron-variant, upstream-variant-2KB
rs5829692 -- 19,354,423(+) CACAC(-/AC)GGGAT intron-variant
rs11676363 -- 19,355,284(+) CTCTC(C/T)TCTTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OSR1 Gene

Variant ID Type Subtype PubMed ID
nsv819849 CNV Gain 19587683

Relevant External Links for OSR1 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OSR1 Gene

Disorders for OSR1 Gene

Relevant External Links for OSR1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with OSR1: view

No data available for UniProtKB/Swiss-Prot for OSR1 Gene

Publications for OSR1 Gene

  1. Molecular cloning and characterization of OSR1 on human chromosome 2p24. (PMID: 12119563) Katoh M. (Int. J. Mol. Med. 2002) 2 3 4
  2. Molecular analysis of odd-skipped, a zinc finger encoding segmentation gene with a novel pair-rule expression pattern. (PMID: 2120051) Coulter D.E. … Schedl P. (EMBO J. 1990) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4

Products for OSR1 Gene

  • Addgene plasmids for OSR1

Sources for OSR1 Gene

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