Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OSGIN2 Gene

protein-coding   GIFtS: 45
GCID: GC08P090984

Oxidative Stress Induced Growth Inhibitor Family Member...

(Previous name: chromosome 8 open reading frame 1)
(Previous symbol: C8orf1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Oxidative Stress Induced Growth Inhibitor Family Member 21 2
C8orf11 2 3 5
hT412 3
Chromosome 8 Open Reading Frame 11
Oxidative Stress-Induced Growth Inhibitor 22

External Ids:    HGNC: 13551   Entrez Gene: 7342   Ensembl: ENSG000001648237   OMIM: 6045985   UniProtKB: Q9Y2363   

Export aliases for OSGIN2 gene to outside databases

Previous GC identifer: GC08P086124


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for OSGIN2 Gene: 
OSGIN2 (oxidative stress induced growth inhibitor family member 2) is a protein-coding gene. Diseases associated with OSGIN2 include nijmegen breakage syndrome, and gastric cancer. GO annotations related to this gene include molecular_function. An important paralog of this gene is OSGIN1.

UniProtKB/Swiss-Prot: OSGI2_HUMAN, Q9Y236
Function: May be involved in meiosis or the maturation of germ cells




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_008046.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OSGIN2 gene promoter:
         USF1   AML1a   USF-1   USF2   USF-1:USF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): OSGIN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for OSGIN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSGIN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q21   Ensembl cytogenetic band:  8q21.3   HGNC cytogenetic band: 8q21

OSGIN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OSGIN2 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P090984:  view genomic region     (about GC identifiers)

Start:
90,914,087 bp from pter      End:
90,940,116 bp from pter
Size:
26,030 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OSGI2_HUMAN, Q9Y236 (See protein sequence)
Recommended Name: Oxidative stress-induced growth inhibitor 2  
Size: 505 amino acids; 56672 Da
Sequence caution: Sequence=AAH31054.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Alternative splicing: 2 isoforms:  Q9Y236-1   Q9Y236-2   (Ref.3 (AAH31054) sequence has a frameshift in position 3)

Explore the universe of human proteins at neXtProt for OSGIN2: NX_Q9Y236

Explore proteomics data for OSGIN2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9Y236

  • OSGIN2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OSGIN2 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001119583.1  NP_004328.1  

    ENSEMBL proteins: 
     ENSP00000297438   ENSP00000396445   ENSP00000431029  

    Human Recombinant Protein Products for OSGIN2: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for OSGIN2
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for OSGIN2
    GenScript Custom Purified and Recombinant Proteins Services for OSGIN2
    Novus Biologicals OSGIN2 Proteins
    Novus Biologicals OSGIN2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OSGIN2 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    OSGIN2 for ontologies           About GeneDecksing



    OSGIN2 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for OSGIN2
    GenScript Custom Superior Antibodies Services for OSGIN2
    Novus Biologicals OSGIN2 Antibodies
    Abcam antibodies for OSGIN2
    Cloud-Clone Corp. Antibodies for OSGIN2 
    ThermoFisher Antibodies for OSGIN2
    LSBio Antibodies in human, mouse, rat for OSGIN2 

    Assay Products for OSGIN2: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for OSGIN2
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for OSGIN2
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for OSGIN2 
    Cloud-Clone Corp. CLIAs for OSGIN2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q9Y236

    UniProtKB/Swiss-Prot: OSGI2_HUMAN, Q9Y236
    Similarity: Belongs to the OKL38 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OSGI2_HUMAN, Q9Y236
    Function: May be involved in meiosis or the maturation of germ cells

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    OSGIN2 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for OSGIN2:
     Decreased viability of wild-ty  G0/1 arrest  Increased G1 DNA content 

         1 MGI phenotypic allele for Osgin2 (no phenotypes)

    OSGIN2 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OSGIN2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OSGIN2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OSGIN2 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OSGIN2 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSGIN2
    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate OSGIN2 (see all 33):
    hsa-miR-562 hsa-miR-607 hsa-miR-632 hsa-miR-449a hsa-miR-570 hsa-miR-1244 hsa-miR-186 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidOSGIN2 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for OSGIN2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSGIN2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for OSGIN2
    Sirion Biotech Customized adenovirus for overexpression of OSGIN2

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for OSGIN2 (see all 13)
    OriGene ORF clones in mouse, rat for OSGIN2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): OSGIN2 (NM_001126111)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OSGIN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSGIN2
    Sirion Biotech Customized lentivirus for stable overexpression of OSGIN2 
                         Customized lentivirus expression plasmids for stable overexpression of OSGIN2 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for OSGIN2
    Search LifeMap BioReagents cell lines for OSGIN2
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSGIN2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OSGIN2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for OSGIN2 (Q9Y2363 ENSP000003964454) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPL3P390233I2D: score=4 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007126meiosis NAS--
    GO:0007281germ cell development NAS--

    OSGIN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OSGIN2 (OSGI2)

    Search CenterWatch for drugs/clinical trials and news about OSGIN2 / OSGI2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OSGIN2 gene (2 alternative transcripts): 
    NM_001126111.1  NM_004337.2  

    Unigene Cluster for OSGIN2:

    Oxidative stress induced growth inhibitor family member 2
    Hs.436445  [show with all ESTs]
    Unigene Representative Sequence: NM_001126111
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297438(uc003yeg.3) ENST00000451899(uc003yeh.3) ENST00000520659

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSGIN2
    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate OSGIN2 (see all 33):
    hsa-miR-562 hsa-miR-607 hsa-miR-632 hsa-miR-449a hsa-miR-570 hsa-miR-1244 hsa-miR-186 hsa-miR-3148
    SwitchGear 3'UTR luciferase reporter plasmidOSGIN2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for OSGIN2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSGIN2
    Clone
    Products:
         
    OriGene clones in human, mouse for OSGIN2 (see all 13)
    OriGene ORF clones in mouse, rat for OSGIN2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): OSGIN2 (NM_001126111)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OSGIN2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSGIN2
    Sirion Biotech Customized lentivirus for stable overexpression of OSGIN2 
                         Customized lentivirus expression plasmids for stable overexpression of OSGIN2 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for OSGIN2
    OriGene qSTAR qPCR primer pairs in human, mouse for OSGIN2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OSGIN2
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSGIN2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSGIN2

    Additional mRNA sequence: 

    AF061326.1 BC031054.1 

    5 DOTS entries:

    DT.444356  DT.92429221  DT.86836431  DT.40112330  DT.95268687 

    24/116 AceView cDNA sequences (see all 116):

    BQ575056 BU735109 AI572275 AI078670 AL705372 AA789031 AI687791 AA622749 
    CA436292 AF061326 NM_004337 BF002136 BM788710 BM696488 BM722844 AA293108 
    CB120481 AI688382 BU740525 BM790949 AI076467 BX117972 BQ220931 AA876842 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OSGIN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGTGAGCAT
    OSGIN2 Expression
    About this image


    See OSGIN2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OSGIN2

    SOURCE GeneReport for Unigene cluster: Hs.436445

    UniProtKB/Swiss-Prot: OSGI2_HUMAN, Q9Y236
    Tissue specificity: Ubiquitous. Expressed at higher levels in testis and ovary

        SABiosciences Custom PCR Arrays for OSGIN2
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for OSGIN2
    OriGene qSTAR qPCR primer pairs in human, mouse for OSGIN2
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OSGIN2
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSGIN2
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSGIN2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSGIN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for OSGIN2 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Osgin21 , 5 oxidative stress induced growth inhibitor family member more1, 5 89.74(n)1
    92.35(a)1
      4 (6.66 cM)5
    2092121  NM_145950.41  NP_666062.31 
     159971215 
    chicken
    (Gallus gallus)
    Aves OSGIN21 oxidative stress induced growth inhibitor family member more 76.59(n)
    80.71(a)
      420217  XM_418327.3  XP_418327.3 
    lizard
    (Anolis carolinensis)
    Reptilia OSGIN26
    Uncharacterized protein
    75(a)
    1 ↔ 1
    4(21492586-21507712)
    zebrafish
    (Danio rerio)
    Actinopterygii BC045855.12   -- 73.64(n)   393155  BC045855.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_F30B5.41 Protein F30B5.4 46.68(n)
    34.58(a)
      177185  NM_068113.2  NP_500514.1 


    ENSEMBL Gene Tree for OSGIN2 (if available)
    TreeFam Gene Tree for OSGIN2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OSGIN2 gene
    OSGIN12  
    1 SIMAP similar gene for OSGIN2 using alignment to 2 protein entries:     OSGI2_HUMAN (see all proteins):
    OSGIN1

    OSGIN2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/566 SNPs in OSGIN2 are shown (see all 566)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1506718401,2
    --90912143(+) ACTACA/GGAGAA 1 -- us2k10--------
    rs1929300851,2
    --90912247(+) TATATC/GCTAAG 1 -- us2k10--------
    rs1399468591,2
    --90912331(+) TCAATA/GGACAA 1 -- us2k10--------
    rs791352221,2
    C,F--90912372(+) TAGTAG/CCATTC 1 -- us2k12Minor allele frequency- C:0.07WA 120
    rs101112321,2
    C,H--90912451(+) tgaaaT/Caggcc 1 -- us2k14Minor allele frequency- C:0.00NS EA 416
    rs1180766891,2
    F--90912646(+) AGCACG/AAGAGT 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs733044761,2
    C--90912728(+) AAGGAT/CAAATA 1 -- us2k14Minor allele frequency- C:0.08WA NA EA 360
    rs1775371,2
    C,F,H--90912936(+) TAGTAG/AGTGTA 2 -- us2k110Minor allele frequency- A:0.00MN NS NA WA CSA 370
    rs1498531911,2
    --90912999(+) GGGCCA/GTGCTA 2 -- us2k10--------
    rs1405483011,2
    C--90913074(+) GGTAC-/TTTA  
            
    TTTAT
    2 -- us2k10--------

    HapMap Linkage Disequilibrium report for OSGIN2 (90914087 - 90940116 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for OSGIN2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv6296CNV Insertion18451855

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing OSGIN2
    DNA2.0 Custom Variant and Variant Library Synthesis for OSGIN2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604598    OMIM disorders: --

    2 diseases for OSGIN2:    About MalaCards
    nijmegen breakage syndrome    gastric cancer


    OSGIN2 for disorders           About GeneDecksing


    Export disorders for OSGIN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OSGIN2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with OSGIN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sequence analysis of an 800-kb genomic DNA region on chromosome 8q21 that contains the Nijmegen breakage syndrome gene, NBS1. (PubMed id 9933573)1, 2, 3 Tauchi H.... Nakamura Y. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    4. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    5. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
    6. Transcriptome analysis of human gastric cancer. (PubMed id 16341674)1 Oh J.H....Kim N.S. (2005)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 734 HGNC: 1355 AceView: C8orf1 Ensembl:ENSG00000164823 euGenes: HUgn734
    ECgene: OSGIN2 H-InvDB: OSGIN2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OSGIN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OSGIN2 gene:
    Search GeneIP for patents involving OSGIN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for OSGIN2  
     OriGene qPCR primer pairs and template standards for OSGIN2   OriGene Protein Over-expression Lysate for OSGIN2  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for OSGIN2  
     OriGene qSTAR qPCR primer pairs in human, mouse for OSGIN2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for OSGIN2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for OSGIN2   OriGene Custom Protein Services for OSGIN2  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OSGIN2
     QIAGEN SeqTarget long-range PCR primers for resequencing OSGIN2
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSGIN2
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSGIN2
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSGIN2
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSGIN2
     GenScript Custom Purified and Recombinant Proteins Services for OSGIN2 GenScript cDNA clones with any tag delivered in your preferred vector for OSGIN2
     GenScript Custom Assay Services for OSGIN2 GenScript Custom Superior Antibodies Services for OSGIN2
     GenScript Custom overexpressing Cell Line Services for OSGIN2 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in OSGIN2 promoter
     Search Chromatin IP Primers for OSGIN2
     RT2 qPCR Primer Assay in human, mouse, rat OSGIN2
     Search GNC Networks for OSGIN2
     SABiosciences Custom PCR Arrays for OSGIN2
     Search Tocris compounds for OSGIN2 (OSGI2)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     OSGIN2 antibodies
     OSGIN2 proteins
     OSGIN2 lysates
     Antibodies for OSGIN2
     See all of Abcam's Antibodies, Kits and Proteins for OSGIN2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for OSGIN2
     Antibodies for OSGIN2
     ELISAs for OSGIN2
     CLIAs for OSGIN2
     Search LifeMap BioReagents cell lines for OSGIN2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSGIN2
     SwitchGear 3'UTR luciferase reporter plasmids for OSGIN2
     SwitchGear Promoter luciferase reporter plasmids for OSGIN2
     ThermoFisher Antibodies for OSGIN2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSGIN2
     inGenious Targeting Laboratory - Custom generated mouse model solutions for OSGIN2
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OSGIN2
    Customized:
     lentivirus for stable overexpression of OSGIN2
     lentivirus expression plasmids for stable overexpression of OSGIN2
     adenovirus for overexpression of OSGIN2
     LSBio Antibodies in human, mouse, rat for OSGIN2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      OSGIN2 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4