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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

OSGIN1 Gene

protein-coding   GIFtS: 52
GCID: GC16P083982

Oxidative Stress Induced Growth Inhibitor 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Oxidative Stress Induced Growth Inhibitor 11 2     BDGI2
Bone Marrow Stromal Cell-Derived Growth Inhibitor1 2     Oxidative Stress-Induced Growth Inhibitor 12
Ovary, Kidney And Liver Protein 382 3     huOKL383
Pregnancy-Induced Growth Inhibitor OKL382 3     EC 1.6.58
OKL382 3     EC 2.4.2.78
Pregnancy Induced Growth Inhibitor1     EC 2.7.1.1308

External Ids:    HGNC: 300931   Entrez Gene: 299482   Ensembl: ENSG000001409617   OMIM: 6079755   UniProtKB: Q9UJX03   

Export aliases for OSGIN1 gene to outside databases

Previous GC identifers: GC16P082541 GC16P069733


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OSGIN1 Gene:
This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is
regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release
from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules.
The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring
read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase
(MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. (provided by RefSeq,
Aug 2011)

GeneCards Summary for OSGIN1 Gene: 
OSGIN1 (oxidative stress induced growth inhibitor 1) is a protein-coding gene. Diseases associated with OSGIN1 include hepatocellular carcinoma, and endotheliitis. GO annotations related to this gene include growth factor activity. An important paralog of this gene is OSGIN2.

UniProtKB/Swiss-Prot: OSGI1_HUMAN, Q9UJX0
Function: Regulates the differentiation and proliferation of normal cells through the regulation of cell death




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010498.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the OSGIN1 gene promoter:
         CREB   ER-alpha   HOXA3   FOXO3a   FOXO3   FOXO3b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): OSGIN1 promoter sequence
   Search SABiosciences Chromatin IP Primers for OSGIN1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSGIN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.3   Ensembl cytogenetic band:  16q23.3   HGNC cytogenetic band: 16q23.3

OSGIN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OSGIN1 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P083982:  view genomic region     (about GC identifiers)

Start:
83,981,887 bp from pter      End:
83,999,937 bp from pter
Size:
18,051 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: OSGI1_HUMAN, Q9UJX0 (See protein sequence)
Recommended Name: Oxidative stress-induced growth inhibitor 1  
Size: 560 amino acids; 60849 Da
Miscellaneous: Loss of OSGIN1 protein disturbs the balance between cell growth, differentiation, and cell death in
normal tissue, resulting in uncontrolled growth and formation of tumors
Sequence caution: Sequence=AAF06662.1; Type=Frameshift; Positions=493, 523, 534, 554; Sequence=AAK01722.2;
Type=Erroneous gene model prediction;
Secondary accessions: Q52M33 Q86UQ1 Q96S88 Q9BZ70
Alternative splicing: 3 isoforms:  Q9UJX0-1   Q9UJX0-2   Q9UJX0-3   

Explore the universe of human proteins at neXtProt for OSGIN1: NX_Q9UJX0

Explore proteomics data for OSGIN1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9UJX0

  • 3 DME Specific Peptides for OSGIN1 (Q9UJX0)
     AFRRAVD  SYLLSGY  PVIIVGN 

    OSGIN1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    OSGIN1 Protein Expression
    REFSEQ proteins: NP_892026.1  
    ENSEMBL proteins: 
     ENSP00000456965   ENSP00000355374   ENSP00000343376   ENSP00000376983   ENSP00000462048  
     ENSP00000457157  

    Human Recombinant Protein Products for OSGIN1: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for OSGIN1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    OSGIN1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for OSGIN1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ProtoNet protein and cluster: Q9UJX0

    UniProtKB/Swiss-Prot: OSGI1_HUMAN, Q9UJX0
    Similarity: Belongs to the OKL38 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: OSGI1_HUMAN, Q9UJX0
    Function: Regulates the differentiation and proliferation of normal cells through the regulation of cell death
    Induction: By pregnancy

         Enzyme Numbers (IUBMB): EC 1.6.52 EC 2.7.1.1302 EC 2.4.2.72

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008083growth factor activity IDA11459809
    GO:0016491oxidoreductase activity ----
         
    OSGIN1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for OSGIN1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for OSGIN1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for OSGIN1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for OSGIN1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OSGIN1 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSGIN1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate OSGIN1:
    hsa-miR-1207-3p hsa-miR-3918
    SwitchGear 3'UTR luciferase reporter plasmidOSGIN1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Sino Biological Human cDNA Clone for OSGIN1
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                         Customized lentivirus expression plasmids for stable overexpression of OSGIN1 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSGIN1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for OSGIN1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for OSGIN1 (ENSP000003433764) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development IEA--
    GO:0030154cell differentiation IEA--
    GO:0030308negative regulation of cell growth IDA11459809
    GO:0055114oxidation-reduction process ----

    OSGIN1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for OSGIN1 (OSGI1)

    Search CenterWatch for drugs/clinical trials and news about OSGIN1 / OSGI1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for OSGIN1 gene (3 alternative transcripts): 
    NM_182981.2  NM_013370.3  NM_182980.2  

    Unigene Cluster for OSGIN1:

    Oxidative stress induced growth inhibitor 1
    Hs.128055  [show with all ESTs]
    Unigene Representative Sequence: NM_182981
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000561552 ENST00000361711 ENST00000343939(uc002fha.3 uc002fhb.3)
    ENST00000393306(uc002fhc.3) ENST00000565123 ENST00000563543 ENST00000567707

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSGIN1
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate OSGIN1:
    hsa-miR-1207-3p hsa-miR-3918
    SwitchGear 3'UTR luciferase reporter plasmidOSGIN1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for OSGIN1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSGIN1
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    OriGene clones in human, mouse for OSGIN1 (see all 12)
    OriGene ORF clones in mouse, rat for OSGIN1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): OSGIN1 (NM_182981)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OSGIN1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSGIN1
    Sirion Biotech Customized lentivirus for stable overexpression of OSGIN1 
                         Customized lentivirus expression plasmids for stable overexpression of OSGIN1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for OSGIN1
    OriGene qSTAR qPCR primer pairs in human, mouse for OSGIN1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OSGIN1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSGIN1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSGIN1

    Additional mRNA sequence: 

    AF191740.1 AK290383.1 AY037158.1 AY258068.1 BC020434.1 BC032476.1 BC093687.1 BC113417.1 

    5 DOTS entries:

    DT.100766000  DT.100787074  DT.100787073  DT.95262661  DT.95262659 

    24/201 AceView cDNA sequences (see all 201):

    BQ012584 BM920231 BU741097 BQ012697 CD366355 N74699 BC052592 BQ956581 
    CD366665 AW952184 CK819852 BU859877 BM142050 BU072491 AI283870 BM718683 
    BQ721699 AK124050 AA642982 BU072788 BC000286 BM976436 CA867400 AI139636 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for OSGIN1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10a · 10b
    SP1:                    -     -     -                                             
    SP2:                    -     -     -                                             
    SP3:                          -     -                                             
    SP4:                                                                              
    SP5:                                                                              


    ECgene alternative splicing isoforms for OSGIN1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    OSGIN1 expression in normal human tissues (normalized intensities)      OSGIN1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGCCGCTGG
    OSGIN1 Expression
    About this image


    OSGIN1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 2 entries
             umbilical cord reticulocytes   
     
     Ovary (Reproductive System)
             Granulosa Cells Primary Follicle
     
     Umbilical Cord (Extraembryonic Tissues)
             umbilical cord reticulocytes   

    See OSGIN1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for OSGIN1

    SOURCE GeneReport for Unigene cluster: Hs.128055

    UniProtKB/Swiss-Prot: OSGI1_HUMAN, Q9UJX0
    Tissue specificity: Ubiquitous. Highest expression in the ovary, testis, kidney, and liver

        SABiosciences Expression via Pathway-Focused PCR Array including OSGIN1: 
              Growth Factors in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSGIN1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for OSGIN1 gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Osgin11 , 5 oxidative stress induced growth inhibitor 11, 5 82.32(n)1
    81.76(a)1
      8 (67.71 cM)5
    718391  NM_027950.11  NP_082226.11 
     1194341245 
    chicken
    (Gallus gallus)
    Aves OSGIN11 oxidative stress induced growth inhibitor 1 61.36(n)
    63.73(a)
      415706  XM_414073.3  XP_414073.2 
    lizard
    (Anolis carolinensis)
    Reptilia OSGIN16
    oxidative stress induced growth inhibitor 1
    61(a)
    1 ↔ 1
    LGc(6922942-6936247)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:560051 zgc:56005 58.99(n)
    57.24(a)
      393155  NM_200186.1  NP_956480.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0113901 AGAP011390-PA 55.87(n)
    43.18(a)
      4577558  XM_001238004.1  XP_001238005.1 
    worm
    (Caenorhabditis elegans)
    Secernentea F30B5.46
    Uncharacterized protein F30B5.4
    27(a)
    1 → many
    IV(4205975-4218248)


    ENSEMBL Gene Tree for OSGIN1 (if available)
    TreeFam Gene Tree for OSGIN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for OSGIN1 gene
    OSGIN22  
    1 SIMAP similar gene for OSGIN1 using alignment to 4 protein entries:     OSGI1_HUMAN (see all proteins):
    OSGIN2

    OSGIN1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/639 SNPs in OSGIN1 are shown (see all 639)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0652384
    ----see VAR_0652382 N T mis40--------
    VAR_0652374
    ----see VAR_0652372 P L mis40--------
    rs1502632621,2
    C--83985495(+) TCCTT-/CCCTCC 1 -- us2k10--------
    rs1132707581,2
    C--83985500(+) TCCTCC/TTTCTC 1 -- us2k10--------
    rs1824724051,2
    --83985551(+) TCCCTC/GCCTTC 1 -- us2k10--------
    rs3715173421,2
    C--83995569(+) CTTTT-/TTTTTT 1 -- int10--------
    rs358427171,2
    C--83995617(+) TTAAC-/CATGAG 1 -- int10--------
    rs582920851,2
    C--83997029(+) TTGGG-/GCTTAG 1 -- int10--------
    rs22448991,2,4
    C,F,A--84991018(-) GCACAG/TCCTGG 1 -- us2k111Minor allele frequency- T:0.12WA NA CSA EA 2541
    rs22448981,2,4
    C,F,A--84991024(+) TGTGCG/CTGACT 1 -- us2k112Minor allele frequency- C:0.11WA NA CSA EA 2715

    HapMap Linkage Disequilibrium report for OSGIN1 (83981887 - 83999937 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for OSGIN1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv528396CNV Loss19592680
    dgv2928n71CNV Loss21882294
    nsv907040CNV Loss21882294
    nsv907038CNV Gain21882294
    nsv471106CNV Gain18288195
    nsv517566CNV Gain+Loss19592680


    Human Gene Mutation Database (HGMD): OSGIN1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing OSGIN1
    DNA2.0 Custom Variant and Variant Library Synthesis for OSGIN1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607975    OMIM disorders: --

    3 diseases for OSGIN1:    About MalaCards
    hepatocellular carcinoma    endotheliitis    breast cancer


    OSGIN1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): OSGIN1
    Human Genome Epidemiology (HuGE) Navigator: OSGIN1 (2 documents)

    Export disorders for OSGIN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for OSGIN1 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with OSGIN1)
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    1. Genomic structure of human OKL38 gene and its differential expression in kidney carcinogenesis. (PubMed id 14570898)1, 2, 3 Ong C.K.... Huynh H.T. (2004)
    2. Cloning and characterization of a novel pregnancy-induced growth inhibitor in mammary gland. (PubMed id 11459809)1, 2, 3 Huynh H.T.... Chan T.W.M. (2001)
    3. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (2010)
    4. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids. (PubMed id 17192422)1, 9 Li R....Berliner J.A. (2007)
    7. Interaction of OKL38 and p53 in regulating mitochondri al structure and function. (PubMed id 22912861)1 Hu J....Wang Y. (2012)
    8. Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1. (PubMed id 21737788)1 Romanoski C.E....Lusis A.J. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Ultrafine particles from diesel vehicle emissions at different driving cycles induce differential vascular pro-inflammatory response s: implication of chemical components and NF-kappaB signaling. (PubMed id 20307321)1 Li R....Hsiai T. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29948 HGNC: 30093 AceView: MLYCDandOKL38 Ensembl:ENSG00000140961 euGenes: HUgn29948
    ECgene: OSGIN1 H-InvDB: OSGIN1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for OSGIN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for OSGIN1 gene:
    Search GeneIP for patents involving OSGIN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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