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Aliases for OSER1 Gene

Aliases for OSER1 Gene

  • Oxidative Stress Responsive Serine-Rich 1 2 3
  • Peroxide-Inducible Transcript 1 Protein 3 4
  • Oxidative Stress-Responsive Protein 1 3 4
  • Oxidative Stress-Responsive 1 2 3
  • C20orf111 3 4
  • Oxidative Stress-Responsive Serine-Rich Protein 1 3
  • Chromosome 20 Open Reading Frame 111 2
  • Peroxide-Inducible Transcript 1 2
  • DJ1183I21.1 3
  • HSPC207 3
  • Perit1 3
  • OSR1 3

External Ids for OSER1 Gene

Previous Symbols for OSER1 Gene

  • C20orf111

Summaries for OSER1 Gene

GeneCards Summary for OSER1 Gene

OSER1 (Oxidative Stress Responsive Serine-Rich 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OSER1 Gene

Genomics for OSER1 Gene

Genomic Location for OSER1 Gene

Start:
44,195,939 bp from pter
End:
44,210,982 bp from pter
Size:
15,044 bases
Orientation:
Minus strand

Genomic View for OSER1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OSER1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OSER1 Gene

No data available for Regulatory Elements for OSER1 Gene

Proteins for OSER1 Gene

  • Protein details for OSER1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NX31-OSER1_HUMAN
    Recommended name:
    Oxidative stress-responsive serine-rich protein 1
    Protein Accession:
    Q9NX31
    Secondary Accessions:
    • B2RCK4
    • O95912
    • Q9NZ84
    • Q9P0R8

    Protein attributes for OSER1 Gene

    Size:
    292 amino acids
    Molecular mass:
    31779 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAF36127.1; Type=Frameshift; Positions=201, 195; Evidence={ECO:0000305}; Sequence=AAF67625.1; Type=Frameshift; Positions=201, 287; Evidence={ECO:0000305}; Sequence=BAA91191.1; Type=Frameshift; Positions=183; Evidence={ECO:0000305};

neXtProt entry for OSER1 Gene

Proteomics data for OSER1 Gene at MOPED

Post-translational modifications for OSER1 Gene

  • Modification sites at PhosphoSitePlus
  • Ubiquitination at Lys59 and Lys190

Other Protein References for OSER1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OSER1 Gene

Domains for OSER1 Gene

Protein Domains for OSER1 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with OSER1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for OSER1 Gene

Function for OSER1 Gene

Phenotypes for OSER1 Gene

GenomeRNAi human phenotypes for OSER1:
genes like me logo Genes that share phenotypes with OSER1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OSER1 Gene

Localization for OSER1 Gene

No data available for Gene Ontology (GO) - Cellular Components for OSER1 Gene

Pathways for OSER1 Gene

SuperPathways for OSER1 Gene

No Data Available

Interacting Proteins for OSER1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000255174%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000255174 for OSER1 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for OSER1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070301 cellular response to hydrogen peroxide IEA --
genes like me logo Genes that share ontologies with OSER1: view

No data available for Pathways by source for OSER1 Gene

Transcripts for OSER1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for OSER1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e
SP1: - - -
SP2: - - - - - - -
SP3: - - - -
SP4: - - -
SP5: - - - - - - - -
SP6: - - - - - -
SP7:

Relevant External Links for OSER1 Gene

GeneLoc Exon Structure for
OSER1
ECgene alternative splicing isoforms for
OSER1

Expression for OSER1 Gene

mRNA expression in normal human tissues for OSER1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OSER1 Gene

This gene is overexpressed in Whole Blood (4.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OSER1 Gene

genes like me logo Genes that share expressions with OSER1: view

Orthologs for OSER1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OSER1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C20H20orf111 36
  • 99.54 (n)
  • 99.66 (a)
OSER1 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OSER1 36
  • 91.64 (n)
  • 91.07 (a)
OSER1 37
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C24H20orf111 36
  • 94.29 (n)
  • 93.15 (a)
OSER1 37
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 3230401D17Rik 16
Oser1 36
  • 87.86 (n)
  • 86.94 (a)
Oser1 37
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OSER1 37
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia OSER1 37
  • 73 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Oser1 36
  • 87.4 (n)
  • 85.91 (a)
chicken
(Gallus gallus)
Aves C20H20ORF111 36
  • 69.63 (n)
  • 66.44 (a)
C20H20ORF111 37
  • 66 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia OSER1 37
  • 50 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.8276 36
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC76290 36
oser1 36
  • 62.51 (n)
  • 61.92 (a)
zebrafish
(Danio rerio)
Actinopterygii -- 36
oser1 36
  • 54.8 (n)
  • 48.4 (a)
oser1 37
  • 44 (a)
OneToOne
Species with no ortholog for OSER1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OSER1 Gene

ENSEMBL:
Gene Tree for OSER1 (if available)
TreeFam:
Gene Tree for OSER1 (if available)

Paralogs for OSER1 Gene

No data available for Paralogs for OSER1 Gene

Variants for OSER1 Gene

Sequence variations from dbSNP and Humsavar for OSER1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs8268 -- 44,197,289(+) GAATA(C/T)ACTTC synonymous-codon, reference
rs9346 - 44,197,710(-) AGCAG(G/T)GAGAA missense, reference
rs9875 -- 44,196,847(+) TGATC(C/T)GCTCG utr-variant-3-prime
rs11274 -- 44,197,739(+) GTAGA(C/T)CTAAA synonymous-codon, reference
rs956609 -- 44,208,801(+) GCTCT(C/T)ACCGA intron-variant, upstream-variant-2KB, utr-variant-5-prime

Relevant External Links for OSER1 Gene

HapMap Linkage Disequilibrium report
OSER1
Human Gene Mutation Database (HGMD)
OSER1

No data available for Structural Variations from Database of Genomic Variants (DGV) for OSER1 Gene

Disorders for OSER1 Gene

No disorders were found for OSER1 Gene.

No data available for UniProtKB/Swiss-Prot for OSER1 Gene

Publications for OSER1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Cardiac myocyte gene expression profiling during H2O2-induced apoptosis. (PMID: 17148688) Clerk A. … Sugden P.H. (Physiol. Genomics 2007) 2 3
  4. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PMID: 11042152) Zhang Q.-H. … Chen Z. (Genome Res. 2000) 3 4
  5. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4

Products for OSER1 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate OSER1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for OSER1
    • Block miRNA regulation of OSER1 using miScript Target Protectors

    Sources for OSER1 Gene

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