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Aliases for OSER1 Gene

Aliases for OSER1 Gene

  • Oxidative Stress Responsive Serine Rich 1 2 3
  • Oxidative Stress Responsive Serine-Rich 1 2 3 5
  • Peroxide-Inducible Transcript 1 Protein 3 4
  • Oxidative Stress-Responsive Protein 1 3 4
  • Oxidative Stress-Responsive 1 2 3
  • C20orf111 3 4
  • Chromosome 20 Open Reading Frame 111 2
  • Peroxide-Inducible Transcript 1 2
  • DJ1183I21.1 3
  • HSPC207 3
  • Perit1 3
  • Osr1 3

External Ids for OSER1 Gene

Previous HGNC Symbols for OSER1 Gene

  • C20orf111

Previous GeneCards Identifiers for OSER1 Gene

  • GC20M042824

Summaries for OSER1 Gene

GeneCards Summary for OSER1 Gene

OSER1 (Oxidative Stress Responsive Serine Rich 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OSER1 Gene

Genomics for OSER1 Gene

Regulatory Elements for OSER1 Gene

Enhancers for OSER1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OSER1 on UCSC Golden Path with GeneCards custom track

Promoters for OSER1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around OSER1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OSER1 Gene

44,195,939 bp from pter
44,210,906 bp from pter
14,968 bases
Minus strand

Genomic View for OSER1 Gene

Genes around OSER1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OSER1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OSER1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OSER1 Gene

Proteins for OSER1 Gene

  • Protein details for OSER1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Oxidative stress-responsive serine-rich protein 1
    Protein Accession:
    Secondary Accessions:
    • B2RCK4
    • O95912
    • Q9NZ84
    • Q9P0R8

    Protein attributes for OSER1 Gene

    292 amino acids
    Molecular mass:
    31779 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF36127.1; Type=Frameshift; Positions=201, 195; Evidence={ECO:0000305}; Sequence=AAF67625.1; Type=Frameshift; Positions=201, 287; Evidence={ECO:0000305}; Sequence=BAA91191.1; Type=Frameshift; Positions=183; Evidence={ECO:0000305};

neXtProt entry for OSER1 Gene

Proteomics data for OSER1 Gene at MOPED

Post-translational modifications for OSER1 Gene

  • Ubiquitination at Lys 59 and Lys 190
  • Modification sites at PhosphoSitePlus

Other Protein References for OSER1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for OSER1 Gene

Domains & Families for OSER1 Gene

Protein Domains for OSER1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OSER1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for OSER1 Gene

Function for OSER1 Gene

genes like me logo Genes that share phenotypes with OSER1: view

Animal Model Products

miRNA for OSER1 Gene

miRTarBase miRNAs that target OSER1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OSER1 Gene

Localization for OSER1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for OSER1 Gene

Pathways & Interactions for OSER1 Gene

SuperPathways for OSER1 Gene

No Data Available

Interacting Proteins for OSER1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000255174 for OSER1 Gene via STRING

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for OSER1 Gene


No data available for Pathways by source and SIGNOR curated interactions for OSER1 Gene

Drugs & Compounds for OSER1 Gene

No Compound Related Data Available

Transcripts for OSER1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for OSER1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9a · 9b ^ 10a · 10b · 10c · 10d · 10e
SP1: - - -
SP2: - - - - - - -
SP3: - - - -
SP4: - - -
SP5: - - - - - - - -
SP6: - - - - - -

Relevant External Links for OSER1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OSER1 Gene

mRNA expression in normal human tissues for OSER1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for OSER1 Gene

This gene is overexpressed in Whole Blood (x4.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OSER1 Gene

genes like me logo Genes that share expression patterns with OSER1: view

Primer Products

No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OSER1 Gene

Orthologs for OSER1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OSER1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OSER1 35
  • 91.64 (n)
  • 91.07 (a)
OSER1 36
  • 91 (a)
(Canis familiaris)
Mammalia C24H20orf111 35
  • 94.29 (n)
  • 93.15 (a)
OSER1 36
  • 93 (a)
(Mus musculus)
Mammalia Oser1 35
  • 87.86 (n)
  • 86.94 (a)
Oser1 16
Oser1 36
  • 87 (a)
(Pan troglodytes)
Mammalia C20H20orf111 35
  • 99.54 (n)
  • 99.66 (a)
OSER1 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Oser1 35
  • 87.4 (n)
  • 85.91 (a)
(Monodelphis domestica)
Mammalia OSER1 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia OSER1 36
  • 73 (a)
(Gallus gallus)
Aves C20H20ORF111 35
  • 69.63 (n)
  • 66.44 (a)
C20H20ORF111 36
  • 66 (a)
(Anolis carolinensis)
Reptilia OSER1 36
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia MGC76290 35
oser1 35
  • 62.51 (n)
  • 61.92 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.8276 35
(Danio rerio)
Actinopterygii -- 35
oser1 35
  • 54.8 (n)
  • 48.4 (a)
oser1 36
  • 44 (a)
Species with no ortholog for OSER1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OSER1 Gene

Gene Tree for OSER1 (if available)
Gene Tree for OSER1 (if available)

Paralogs for OSER1 Gene

No data available for Paralogs for OSER1 Gene

Variants for OSER1 Gene

Sequence variations from dbSNP and Humsavar for OSER1 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs9346 - 44,197,710(-) AGCAG(C/G/T)GAGAA reference, missense
rs8268 -- 44,197,289(+) GAATA(C/T)ACTTC reference, synonymous-codon
rs9875 -- 44,196,847(+) TGATC(C/T)GCTCG utr-variant-3-prime
rs11274 -- 44,197,739(+) GTAGA(C/G/T)CTAAA reference, synonymous-codon
rs1007125 -- 44,208,717(-) GGAAG(A/G)ATTTG intron-variant, upstream-variant-2KB

Variation tolerance for OSER1 Gene

Residual Variation Intolerance Score: 42.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.40; 92.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OSER1 Gene

Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for OSER1 Gene

Disorders for OSER1 Gene

Relevant External Links for OSER1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OSER1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OSER1 Gene

Publications for OSER1 Gene

  1. Cardiac myocyte gene expression profiling during H2O2-induced apoptosis. (PMID: 17148688) Clerk A. … Sugden P.H. (Physiol. Genomics 2007) 2 3 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for OSER1 Gene

Sources for OSER1 Gene