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Aliases for OSCP1 Gene

Aliases for OSCP1 Gene

  • Organic Solute Carrier Partner 1 2 3 5
  • Oxidored-Nitro Domain-Containing Protein 1 3 4
  • Oxidored Nitro Domain Containing Protein 2 3
  • Organic Solute Transport Protein 1 3 4
  • C1orf102 3 4
  • NOR1 3 4
  • Chromosome 1 Open Reading Frame 102 2
  • Organic Solute Carrier Protein 1 3
  • Protein OSCP1 3
  • HOSCP1 4

External Ids for OSCP1 Gene

Previous HGNC Symbols for OSCP1 Gene

  • C1orf102

Previous GeneCards Identifiers for OSCP1 Gene

  • GC01M036658
  • GC01M036881
  • GC01M035001

Summaries for OSCP1 Gene

GeneCards Summary for OSCP1 Gene

OSCP1 (Organic Solute Carrier Partner 1) is a Protein Coding gene. Diseases associated with OSCP1 include Nasopharynx Carcinoma and Pharynx Cancer.

UniProtKB/Swiss-Prot for OSCP1 Gene

  • May be involved in drug clearance in the placenta.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OSCP1 Gene

Genomics for OSCP1 Gene

Regulatory Elements for OSCP1 Gene

Enhancers for OSCP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around OSCP1 on UCSC Golden Path with GeneCards custom track

Promoters for OSCP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for OSCP1 Gene

36,415,827 bp from pter
36,450,485 bp from pter
34,659 bases
Minus strand

Genomic View for OSCP1 Gene

Genes around OSCP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OSCP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OSCP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OSCP1 Gene

Proteins for OSCP1 Gene

  • Protein details for OSCP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein OSCP1
    Protein Accession:
    Secondary Accessions:
    • A6NHM5
    • A6NHS9
    • A6NIN9
    • Q4AEJ0
    • Q8N7G2
    • Q8TDF1

    Protein attributes for OSCP1 Gene

    389 amino acids
    Molecular mass:
    44586 Da
    Quaternary structure:
    No Data Available
    • May be involved in the development and/or progression of nosopharyngeal carcinoma.
    • Sequence=AAL89738.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for OSCP1 Gene


neXtProt entry for OSCP1 Gene

Post-translational modifications for OSCP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Antibody Products

  • Abcam antibodies for OSCP1

No data available for DME Specific Peptides for OSCP1 Gene

Domains & Families for OSCP1 Gene

Protein Domains for OSCP1 Gene


Suggested Antigen Peptide Sequences for OSCP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OSCP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for OSCP1 Gene

Function for OSCP1 Gene

Molecular function for OSCP1 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=35.0 uM for p-aminohippurate (PAH) {ECO:0000269 PubMed:16006562}; KM=62.3 uM for tetraethylammonium {ECO:0000269 PubMed:16006562}; Note=In Xenopus laevis oocytes, in a sodium-independent manner.;
UniProtKB/Swiss-Prot Function:
May be involved in drug clearance in the placenta.
genes like me logo Genes that share phenotypes with OSCP1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OSCP1 Gene

Localization for OSCP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OSCP1 Gene

Basal cell membrane. Note=Syncytiotrophoblast in placenta.

Subcellular locations from

Jensen Localization Image for OSCP1 Gene COMPARTMENTS Subcellular localization image for OSCP1 gene
Compartment Confidence
plasma membrane 5
endoplasmic reticulum 3
nucleus 3
cytosol 2
mitochondrion 2
peroxisome 1

Gene Ontology (GO) - Cellular Components for OSCP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009925 basal plasma membrane IEA --
genes like me logo Genes that share ontologies with OSCP1: view

Pathways & Interactions for OSCP1 Gene

SuperPathways for OSCP1 Gene

No Data Available

Interacting Proteins for OSCP1 Gene

Selected Interacting proteins: Q8WVF1-OSCP1_HUMAN for OSCP1 Gene via IID

Gene Ontology (GO) - Biological Process for OSCP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with OSCP1: view

No data available for Pathways by source and SIGNOR curated interactions for OSCP1 Gene

Drugs & Compounds for OSCP1 Gene

(1) Additional Compounds for OSCP1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • Sodium
  • Sodium ion
genes like me logo Genes that share compounds with OSCP1: view

Transcripts for OSCP1 Gene

Unigene Clusters for OSCP1 Gene

Organic solute carrier partner 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OSCP1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b
SP1: - - - - - -
SP2: - - -
SP3: - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: -
SP7: -

Relevant External Links for OSCP1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OSCP1 Gene

mRNA expression in normal human tissues for OSCP1 Gene

mRNA differential expression in normal tissues according to GTEx for OSCP1 Gene

This gene is overexpressed in Testis (x6.7).

Protein differential expression in normal tissues from HIPED for OSCP1 Gene

This gene is overexpressed in Testis (29.5), Liver, secretome (15.7), and Frontal cortex (7.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OSCP1 Gene

Protein tissue co-expression partners for OSCP1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of OSCP1 Gene:


SOURCE GeneReport for Unigene cluster for OSCP1 Gene:


mRNA Expression by UniProt/SwissProt for OSCP1 Gene:

Tissue specificity: Expressed predominantly in testis, also found in placenta and to a lesser extent in thymus and small intestine; abundantly expressed in tumor-derived cell lines (PubMed:16006562). Ubiquitously expressed (PubMed:12819961).
genes like me logo Genes that share expression patterns with OSCP1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for OSCP1 Gene

Orthologs for OSCP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OSCP1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OSCP1 34
  • 88.65 (n)
  • 88.92 (a)
OSCP1 35
  • 89 (a)
(Canis familiaris)
Mammalia OSCP1 34
  • 89.15 (n)
  • 91.28 (a)
OSCP1 35
  • 85 (a)
(Mus musculus)
Mammalia Oscp1 34
  • 85.49 (n)
  • 86.81 (a)
Oscp1 16
Oscp1 35
  • 87 (a)
(Rattus norvegicus)
Mammalia Oscp1 34
  • 86.63 (n)
  • 88.92 (a)
(Monodelphis domestica)
Mammalia OSCP1 35
  • 75 (a)
(Ornithorhynchus anatinus)
Mammalia OSCP1 35
  • 85 (a)
(Pan troglodytes)
Mammalia OSCP1 35
  • 95 (a)
(Gallus gallus)
Aves OSCP1 34
  • 76.52 (n)
  • 81.27 (a)
OSCP1 35
  • 79 (a)
(Anolis carolinensis)
Reptilia OSCP1 35
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia oscp1 34
  • 71.06 (n)
  • 76.78 (a)
Str.15507 34
(Danio rerio)
Actinopterygii LOC100334608 34
  • 70.36 (n)
  • 75.46 (a)
OSCP1 (2 of 2) 35
  • 73 (a)
oscp1a 35
  • 57 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011836 34
  • 48.96 (n)
  • 39.58 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13178 34
  • 48.85 (n)
  • 31.61 (a)
CG13178 35
  • 25 (a)
(Caenorhabditis elegans)
Secernentea R10F2.5 34
  • 50.53 (n)
  • 38.95 (a)
R10F2.5 35
  • 36 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 41 (a)
Species where no ortholog for OSCP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for OSCP1 Gene

Gene Tree for OSCP1 (if available)
Gene Tree for OSCP1 (if available)

Paralogs for OSCP1 Gene

No data available for Paralogs for OSCP1 Gene

Variants for OSCP1 Gene

Sequence variations from dbSNP and Humsavar for OSCP1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11547025 - 36,450,278(-) CATCC(A/C/G/T)GGGAG reference, missense, utr-variant-5-prime
rs2359016 - 36,422,853(+) ATGCT(C/T)GAATT downstream-variant-500B, reference, missense
rs34409118 - 36,432,466(-) CCCCA(A/G)CCATC reference, missense
rs946680 -- 36,431,576(+) TTTCC(A/G)AGAAA intron-variant
rs946681 -- 36,442,561(+) TCGAG(A/C)CTGGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OSCP1 Gene

Variant ID Type Subtype PubMed ID
dgv28e212 CNV loss 25503493
esv2758931 CNV loss 17122850
esv3577808 CNV loss 25503493
nsv509202 CNV insertion 20534489

Variation tolerance for OSCP1 Gene

Residual Variation Intolerance Score: 22.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.95; 93.62% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OSCP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OSCP1 Gene

Disorders for OSCP1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for OSCP1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
nasopharynx carcinoma
  • nasopharyngeal carcinoma
pharynx cancer
  • pharyngeal cancer
- elite association - COSMIC cancer census association via MalaCards
Search OSCP1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for OSCP1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with OSCP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OSCP1 Gene

Publications for OSCP1 Gene

  1. Cloning, expression, and mutation analysis of NOR1, a novel human gene down-regulated in HNE-1 nasopharyngeal carcinoma cell line. (PMID: 12819961) Nie X. … Li G. (J. Cancer Res. Clin. Oncol. 2003) 3 4 22 65
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 65
  3. Preparation of polyclonal antibody specific for NOR1 and detection of its expression pattern in human tissues and nasopharyngeal carcinoma. (PMID: 19727524) Xiang B. … Li G. (Acta Biochim. Biophys. Sin. (Shanghai) 2009) 3 22 65
  4. Isolation and functional characterization of a novel organic solute carrier protein, hOSCP1. (PMID: 16006562) Kobayashi Y. … Yamamoto T. (J. Biol. Chem. 2005) 3 4 65
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65

Products for OSCP1 Gene

Sources for OSCP1 Gene

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