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Aliases for OSCP1 Gene

Aliases for OSCP1 Gene

  • Organic Solute Carrier Partner 1 2 3 5
  • Oxidored-Nitro Domain-Containing Protein 1 3 4
  • Oxidored Nitro Domain Containing Protein 2 3
  • Organic Solute Transport Protein 1 3 4
  • C1orf102 3 4
  • HOSCP1 3 4
  • NOR1 3 4
  • Chromosome 1 Open Reading Frame 102 2
  • Organic Solute Carrier Protein 1 3

External Ids for OSCP1 Gene

Previous HGNC Symbols for OSCP1 Gene

  • C1orf102

Previous GeneCards Identifiers for OSCP1 Gene

  • GC01M036658
  • GC01M036881
  • GC01M035001

Summaries for OSCP1 Gene

GeneCards Summary for OSCP1 Gene

OSCP1 (Organic Solute Carrier Partner 1) is a Protein Coding gene. Diseases associated with OSCP1 include nasopharynx carcinoma and pharynx cancer.

UniProtKB/Swiss-Prot for OSCP1 Gene

  • May be involved in drug clearance in the placenta.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OSCP1 Gene

Genomics for OSCP1 Gene

Regulatory Elements for OSCP1 Gene

Promoters for OSCP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around OSCP1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OSCP1 Gene

Chromosome:
1
Start:
36,415,827 bp from pter
End:
36,450,485 bp from pter
Size:
34,659 bases
Orientation:
Minus strand

Genomic View for OSCP1 Gene

Genes around OSCP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OSCP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OSCP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OSCP1 Gene

Proteins for OSCP1 Gene

  • Protein details for OSCP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WVF1-OSCP1_HUMAN
    Recommended name:
    Protein OSCP1
    Protein Accession:
    Q8WVF1
    Secondary Accessions:
    • A6NHM5
    • A6NHS9
    • A6NIN9
    • Q4AEJ0
    • Q8N7G2
    • Q8TDF1

    Protein attributes for OSCP1 Gene

    Size:
    389 amino acids
    Molecular mass:
    44586 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • May be involved in the development and/or progression of nosopharyngeal carcinoma.
    SequenceCaution:
    • Sequence=AAL89738.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for OSCP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for OSCP1 Gene

Proteomics data for OSCP1 Gene at MOPED

Post-translational modifications for OSCP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OSCP1 Gene

Antibody Products

No data available for DME Specific Peptides for OSCP1 Gene

Domains & Families for OSCP1 Gene

Protein Domains for OSCP1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for OSCP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OSCP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for OSCP1 Gene

Function for OSCP1 Gene

Molecular function for OSCP1 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=35.0 uM for p-aminohippurate (PAH) {ECO:0000269 PubMed:16006562}; KM=62.3 uM for tetraethylammonium {ECO:0000269 PubMed:16006562}; Note=In Xenopus laevis oocytes, in a sodium-independent manner.;
UniProtKB/Swiss-Prot Function:
May be involved in drug clearance in the placenta.
genes like me logo Genes that share phenotypes with OSCP1: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OSCP1 Gene

Localization for OSCP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OSCP1 Gene

Basal cell membrane. Note=Syncytiotrophoblast in placenta.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OSCP1 Gene COMPARTMENTS Subcellular localization image for OSCP1 gene
Compartment Confidence
plasma membrane 5
endoplasmic reticulum 3
nucleus 3
cytosol 2
mitochondrion 2
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for OSCP1 Gene

Pathways & Interactions for OSCP1 Gene

SuperPathways for OSCP1 Gene

No Data Available

Interacting Proteins for OSCP1 Gene

Gene Ontology (GO) - Biological Process for OSCP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with OSCP1: view

No data available for Pathways by source and SIGNOR curated interactions for OSCP1 Gene

Drugs & Compounds for OSCP1 Gene

(1) Additional Compounds for OSCP1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
sodium
  • Sodium
  • Sodium ion
7440-23-5
genes like me logo Genes that share compounds with OSCP1: view

Transcripts for OSCP1 Gene

Unigene Clusters for OSCP1 Gene

Organic solute carrier partner 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OSCP1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b
SP1: - - - - - -
SP2: - - -
SP3: - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: -
SP7: -
SP8:
SP9:

Relevant External Links for OSCP1 Gene

GeneLoc Exon Structure for
OSCP1
ECgene alternative splicing isoforms for
OSCP1

Expression for OSCP1 Gene

mRNA expression in normal human tissues for OSCP1 Gene

mRNA differential expression in normal tissues according to GTEx for OSCP1 Gene

This gene is overexpressed in Testis (x6.7).

Protein differential expression in normal tissues from HIPED for OSCP1 Gene

This gene is overexpressed in Testis (29.5), Liver, secretome (15.7), and Frontal cortex (7.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OSCP1 Gene



SOURCE GeneReport for Unigene cluster for OSCP1 Gene Hs.202207

mRNA Expression by UniProt/SwissProt for OSCP1 Gene

Q8WVF1-OSCP1_HUMAN
Tissue specificity: Expressed predominantly in testis, also found in placenta and to a lesser extent in thymus and small intestine; abundantly expressed in tumor-derived cell lines (PubMed:16006562). Ubiquitously expressed (PubMed:12819961).
genes like me logo Genes that share expression patterns with OSCP1: view

Protein tissue co-expression partners for OSCP1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for OSCP1 Gene

Orthologs for OSCP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OSCP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OSCP1 36
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OSCP1 36
  • 89 (a)
OneToOne
OSCP1 35
  • 88.65 (n)
  • 88.92 (a)
dog
(Canis familiaris)
Mammalia OSCP1 35
  • 89.15 (n)
  • 91.28 (a)
OSCP1 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Oscp1 16
Oscp1 36
  • 87 (a)
OneToOne
Oscp1 35
  • 85.49 (n)
  • 86.81 (a)
oppossum
(Monodelphis domestica)
Mammalia OSCP1 36
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia OSCP1 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Oscp1 35
  • 86.63 (n)
  • 88.92 (a)
chicken
(Gallus gallus)
Aves OSCP1 35
  • 76.52 (n)
  • 81.27 (a)
OSCP1 36
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia OSCP1 36
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia oscp1 35
  • 71.06 (n)
  • 76.78 (a)
Str.15507 35
zebrafish
(Danio rerio)
Actinopterygii OSCP1 (2 of 2) 36
  • 73 (a)
OneToMany
oscp1a 36
  • 57 (a)
OneToMany
LOC100334608 35
  • 70.36 (n)
  • 75.46 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011836 35
  • 48.96 (n)
  • 39.58 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13178 35
  • 48.85 (n)
  • 31.61 (a)
CG13178 36
  • 25 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea R10F2.5 35
  • 50.53 (n)
  • 38.95 (a)
R10F2.5 36
  • 36 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 41 (a)
OneToOne
Species with no ortholog for OSCP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for OSCP1 Gene

ENSEMBL:
Gene Tree for OSCP1 (if available)
TreeFam:
Gene Tree for OSCP1 (if available)

Paralogs for OSCP1 Gene

No data available for Paralogs for OSCP1 Gene

Variants for OSCP1 Gene

Sequence variations from dbSNP and Humsavar for OSCP1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11547025 - 36,450,278(-) CATCC(A/C/G/T)GGGAG reference, missense, utr-variant-5-prime
rs2359016 - 36,422,853(+) ATGCT(C/T)GAATT downstream-variant-500B, reference, missense
rs34409118 - 36,432,466(-) CCCCA(A/G)CCATC reference, missense
rs946680 -- 36,431,576(+) TTTCC(A/G)AGAAA intron-variant
rs953517 -- 36,444,676(+) GGCAG(C/T)TGGGG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OSCP1 Gene

Variant ID Type Subtype PubMed ID
dgv47e1 CNV Complex 17122850
nsv509202 CNV Insertion 20534489

Variation tolerance for OSCP1 Gene

Residual Variation Intolerance Score: 22.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.95; 93.62% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OSCP1 Gene

HapMap Linkage Disequilibrium report
OSCP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OSCP1 Gene

Disorders for OSCP1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for OSCP1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
nasopharynx carcinoma
  • nasopharyngeal carcinoma
pharynx cancer
  • pharyngeal cancer
- elite association - COSMIC cancer census association via MalaCards
Search OSCP1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for OSCP1

Genetic Association Database (GAD)
OSCP1
Human Genome Epidemiology (HuGE) Navigator
OSCP1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OSCP1
genes like me logo Genes that share disorders with OSCP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OSCP1 Gene

Publications for OSCP1 Gene

  1. Cloning, expression, and mutation analysis of NOR1, a novel human gene down-regulated in HNE-1 nasopharyngeal carcinoma cell line. (PMID: 12819961) Nie X. … Li G. (J. Cancer Res. Clin. Oncol. 2003) 3 4 23 67
  2. Preparation of polyclonal antibody specific for NOR1 and detection of its expression pattern in human tissues and nasopharyngeal carcinoma. (PMID: 19727524) Xiang B. … Li G. (Acta Biochim. Biophys. Sin. (Shanghai) 2009) 3 23
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  5. High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy. (PMID: 24270810) Hasson S.A. … Youle R.J. (Nature 2013) 3

Products for OSCP1 Gene

Sources for OSCP1 Gene

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