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Aliases for OSCP1 Gene

Aliases for OSCP1 Gene

  • Organic Solute Carrier Partner 1 2 3
  • NOR1 3 4 6
  • Oxidored-Nitro Domain-Containing Protein 1 3 4
  • Oxidored Nitro Domain Containing Protein 2 3
  • Organic Solute Transport Protein 1 3 4
  • C1orf102 3 4
  • HOSCP1 3 4
  • Chromosome 1 Open Reading Frame 102 2
  • Organic Solute Carrier Protein 1 3
  • Protein OSCP1 3

External Ids for OSCP1 Gene

Previous Symbols for OSCP1 Gene

  • C1orf102

Summaries for OSCP1 Gene

GeneCards Summary for OSCP1 Gene

OSCP1 (Organic Solute Carrier Partner 1) is a Protein Coding gene. Diseases associated with OSCP1 include nasopharynx carcinoma.

UniProtKB/Swiss-Prot for OSCP1 Gene

  • May be involved in drug clearance in the placenta.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OSCP1 Gene

Genomics for OSCP1 Gene

Genomic Location for OSCP1 Gene

Start:
36,415,827 bp from pter
End:
36,450,485 bp from pter
Size:
34,659 bases
Orientation:
Minus strand

Genomic View for OSCP1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OSCP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OSCP1 Gene

No data available for Regulatory Elements for OSCP1 Gene

Proteins for OSCP1 Gene

  • Protein details for OSCP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WVF1-OSCP1_HUMAN
    Recommended name:
    Protein OSCP1
    Protein Accession:
    Q8WVF1
    Secondary Accessions:
    • A6NHM5
    • A6NHS9
    • A6NIN9
    • Q4AEJ0
    • Q8N7G2
    • Q8TDF1

    Protein attributes for OSCP1 Gene

    Size:
    389 amino acids
    Molecular mass:
    44586 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • May be involved in the development and/or progression of nosopharyngeal carcinoma
    SequenceCaution:
    • Sequence=AAL89738.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for OSCP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for OSCP1 Gene

Proteomics data for OSCP1 Gene at MOPED

Post-translational modifications for OSCP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for OSCP1 Gene

No data available for DME Specific Peptides for OSCP1 Gene

Domains for OSCP1 Gene

Protein Domains for OSCP1 Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with OSCP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for OSCP1 Gene

Function for OSCP1 Gene

Molecular function for OSCP1 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties: Kinetic parameters: KM=35.0 uM for p-aminohippurate (PAH) {ECO:0000269 PubMed:16006562}; KM=62.3 uM for tetraethylammonium {ECO:0000269 PubMed:16006562}; Note=In Xenopus laevis oocytes, in a sodium-independent manner.;
UniProtKB/Swiss-Prot Function: May be involved in drug clearance in the placenta.

Phenotypes for OSCP1 Gene

GenomeRNAi human phenotypes for OSCP1:
genes like me logo Genes that share phenotypes with OSCP1: view

miRNA for OSCP1 Gene

miRTarBase miRNAs that target OSCP1

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for OSCP1 Gene

Localization for OSCP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OSCP1 Gene

Basal cell membrane. Note=Syncytiotrophoblast in placenta.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OSCP1 Gene COMPARTMENTS Subcellular localization image for OSCP1 gene
Compartment Confidence
plasma membrane 5
cytosol 2
endoplasmic reticulum 2
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for OSCP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane --
GO:0009925 basal plasma membrane IEA --
genes like me logo Genes that share ontologies with OSCP1: view

Pathways for OSCP1 Gene

SuperPathways for OSCP1 Gene

No Data Available

Interacting Proteins for OSCP1 Gene

Gene Ontology (GO) - Biological Process for OSCP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with OSCP1: view

No data available for Pathways by source for OSCP1 Gene

Compounds for OSCP1 Gene

(1) HMDB Compounds for OSCP1 Gene

Compound Synonyms Cas Number PubMed IDs
Sodium
  • Sodium
7440-23-5
genes like me logo Genes that share compounds with OSCP1: view

Transcripts for OSCP1 Gene

Unigene Clusters for OSCP1 Gene

Organic solute carrier partner 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OSCP1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b
SP1: - - - - - -
SP2: - - -
SP3: - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: -
SP7: -
SP8:
SP9:

Relevant External Links for OSCP1 Gene

GeneLoc Exon Structure for
OSCP1
ECgene alternative splicing isoforms for
OSCP1

Expression for OSCP1 Gene

mRNA expression in normal human tissues for OSCP1 Gene

mRNA differential expression in normal tissues according to GTEx for OSCP1 Gene

This gene is overexpressed in Testis (6.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for OSCP1 Gene

SOURCE GeneReport for Unigene cluster for OSCP1 Gene Hs.202207

mRNA Expression by UniProt/SwissProt for OSCP1 Gene

Q8WVF1-OSCP1_HUMAN
Tissue specificity: Expressed predominantly in testis, also found in placenta and to a lesser extent in thymus and small intestine; abundantly expressed in tumor-derived cell lines (PubMed:16006562). Ubiquitously expressed (PubMed:12819961).
genes like me logo Genes that share expressions with OSCP1: view

Orthologs for OSCP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OSCP1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia OSCP1 37
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia OSCP1 36
  • 88.65 (n)
  • 88.92 (a)
OSCP1 37
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia OSCP1 36
  • 89.15 (n)
  • 91.28 (a)
OSCP1 37
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Oscp1 36
  • 85.49 (n)
  • 86.81 (a)
Oscp1 16
Oscp1 37
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia OSCP1 37
  • 75 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia OSCP1 37
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Oscp1 36
  • 86.63 (n)
  • 88.92 (a)
chicken
(Gallus gallus)
Aves OSCP1 36
  • 76.52 (n)
  • 81.27 (a)
OSCP1 37
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia OSCP1 37
  • 76 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia oscp1 36
  • 71.06 (n)
  • 76.78 (a)
Str.15507 36
zebrafish
(Danio rerio)
Actinopterygii LOC100334608 36
  • 70.36 (n)
  • 75.46 (a)
OSCP1 (2 of 2) 37
  • 73 (a)
OneToMany
oscp1a 37
  • 57 (a)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011836 36
  • 48.96 (n)
  • 39.58 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13178 36
  • 48.85 (n)
  • 31.61 (a)
CG13178 37
  • 25 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea R10F2.5 36
  • 50.53 (n)
  • 38.95 (a)
R10F2.5 37
  • 36 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 41 (a)
OneToOne
Species with no ortholog for OSCP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for OSCP1 Gene

ENSEMBL:
Gene Tree for OSCP1 (if available)
TreeFam:
Gene Tree for OSCP1 (if available)

Paralogs for OSCP1 Gene

No data available for Paralogs for OSCP1 Gene

Variants for OSCP1 Gene

Sequence variations from dbSNP and Humsavar for OSCP1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs946680 -- 36,431,576(+) TTTCC(A/G)AGAAA intron-variant
rs946681 -- 36,442,561(+) TCGAG(A/C)CTGGT intron-variant
rs953517 -- 36,444,676(+) GGCAG(C/T)TGGGG intron-variant
rs953518 -- 36,444,840(+) cataa(A/T)agcac intron-variant
rs1416840 -- 36,422,861(+) ATTCT(A/G)TCCTC missense, reference, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for OSCP1 Gene

Variant ID Type Subtype PubMed ID
dgv47e1 CNV Complex 17122850
nsv509202 CNV Insertion 20534489

Relevant External Links for OSCP1 Gene

HapMap Linkage Disequilibrium report
OSCP1

Disorders for OSCP1 Gene

(1) MalaCards Diseases for OSCP1 Gene

Search for OSCP1 Gene in MalaCards »

(1) University of Copenhagen DISEASES for OSCP1 Gene

Relevant External Links for OSCP1

Genetic Association Database (GAD)
OSCP1
Human Genome Epidemiology (HuGE) Navigator
OSCP1
genes like me logo Genes that share disorders with OSCP1: view

No data available for UniProtKB/Swiss-Prot for OSCP1 Gene

Publications for OSCP1 Gene

  1. Cloning, expression, and mutation analysis of NOR1, a novel human gene down-regulated in HNE-1 nasopharyngeal carcinoma cell line. (PMID: 12819961) Nie X. … Li G. (J. Cancer Res. Clin. Oncol. 2003) 3 4 23
  2. Preparation of polyclonal antibody specific for NOR1 and detection of its expression pattern in human tissues and nasopharyngeal carcinoma. (PMID: 19727524) Xiang B. … Li G. (Acta Biochim. Biophys. Sin. (Shanghai) 2009) 3 23
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49

Products for OSCP1 Gene

Sources for OSCP1 Gene

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