Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OSCP1 Gene

Aliases for OSCP1 Gene

  • Organic Solute Carrier Partner 1 2 3 5
  • Oxidored-Nitro Domain-Containing Protein 1 3 4
  • Oxidored Nitro Domain Containing Protein 2 3
  • Organic Solute Transport Protein 1 3 4
  • C1orf102 3 4
  • NOR1 3 4
  • Chromosome 1 Open Reading Frame 102 2
  • Organic Solute Carrier Protein 1 3
  • Protein OSCP1 3
  • HOSCP1 4

External Ids for OSCP1 Gene

Previous HGNC Symbols for OSCP1 Gene

  • C1orf102

Previous GeneCards Identifiers for OSCP1 Gene

  • GC01M036658
  • GC01M036881
  • GC01M035001

Summaries for OSCP1 Gene

GeneCards Summary for OSCP1 Gene

OSCP1 (Organic Solute Carrier Partner 1) is a Protein Coding gene. Diseases associated with OSCP1 include Pharynx Cancer.

UniProtKB/Swiss-Prot for OSCP1 Gene

  • May be involved in drug clearance in the placenta.

Additional gene information for OSCP1 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OSCP1 Gene

Genomics for OSCP1 Gene

Regulatory Elements for OSCP1 Gene

Enhancers for OSCP1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H036411 1.5 FANTOM5 Ensembl ENCODE dbSUPER 22.1 +38.1 38117 1 TBP HDGF PKNOX1 KLF1 YBX1 RAD21 RFX5 CC2D1A POLR2A NFYB OSCP1 EVA1B ENSG00000116883 SH3D21 MAP7D1 TRAPPC3 GC01M036420 RNU4-27P SNORA63C
GH01H036484 1.6 FANTOM5 Ensembl ENCODE 15.5 -36.6 -36552 4 HDGF FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 CSF3R OSCP1 MRPS15 SNORA63C THRAP3 STK40 MAP7D1 SH3D21 LSM10 GC01M036518
GH01H036370 2.1 FANTOM5 Ensembl ENCODE dbSUPER 11.6 +74.4 74405 10 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A YBX1 FEZF1 DMAP1 CSF3R STK40 AGO3 LSM10 RNU4-27P SNORA63C OSCP1 ENSG00000223944 EVA1B LOC105378647
GH01H036400 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10.2 +49.1 49062 1 ZFP64 ARID4B DMAP1 CBX5 ZNF143 SP3 SP5 ZHX2 MXD4 NFYC OSCP1 LSM10 RNU4-27P
GH01H036420 1.2 Ensembl ENCODE 16 +29.5 29509 1 HDGF PKNOX1 RB1 TBL1XR1 ARNT ARID4B ZNF2 RAD21 RFX5 ZNF366 OSCP1 EVA1B THRAP3 COL8A2 SNORA63C GC01M036420
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around OSCP1 on UCSC Golden Path with GeneCards custom track

Promoters for OSCP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000004812 -16 1400 HDGF PKNOX1 ARID4B SIN3A YY1 GLIS2 ZNF143 KLF7 FOS SP3

Genomic Location for OSCP1 Gene

36,415,827 bp from pter
36,450,485 bp from pter
34,659 bases
Minus strand

Genomic View for OSCP1 Gene

Genes around OSCP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OSCP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OSCP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OSCP1 Gene

Proteins for OSCP1 Gene

  • Protein details for OSCP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein OSCP1
    Protein Accession:
    Secondary Accessions:
    • A6NHM5
    • A6NHS9
    • A6NIN9
    • Q4AEJ0
    • Q8N7G2
    • Q8TDF1

    Protein attributes for OSCP1 Gene

    389 amino acids
    Molecular mass:
    44586 Da
    Quaternary structure:
    No Data Available
    • May be involved in the development and/or progression of nosopharyngeal carcinoma.
    • Sequence=AAL89738.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for OSCP1 Gene


neXtProt entry for OSCP1 Gene

Post-translational modifications for OSCP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for OSCP1 Gene

Domains & Families for OSCP1 Gene

Gene Families for OSCP1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins
  • Transporters

Protein Domains for OSCP1 Gene


Suggested Antigen Peptide Sequences for OSCP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with OSCP1: view

No data available for UniProtKB/Swiss-Prot for OSCP1 Gene

Function for OSCP1 Gene

Molecular function for OSCP1 Gene

UniProtKB/Swiss-Prot BiophysicochemicalProperties:
Kinetic parameters: KM=35.0 uM for p-aminohippurate (PAH) {ECO:0000269 PubMed:16006562}; KM=62.3 uM for tetraethylammonium {ECO:0000269 PubMed:16006562}; Note=In Xenopus laevis oocytes, in a sodium-independent manner.;
UniProtKB/Swiss-Prot Function:
May be involved in drug clearance in the placenta.

Phenotypes From GWAS Catalog for OSCP1 Gene

genes like me logo Genes that share phenotypes with OSCP1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OSCP1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OSCP1 Gene

Localization for OSCP1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OSCP1 Gene

Basal cell membrane. Note=Syncytiotrophoblast in placenta.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for OSCP1 gene
Compartment Confidence
plasma membrane 5
nucleus 3
mitochondrion 2
endoplasmic reticulum 2
cytosol 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoli (2)
  • Nucleus (2)
  • Plasma membrane (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for OSCP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009925 basal plasma membrane IEA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with OSCP1: view

Pathways & Interactions for OSCP1 Gene

SuperPathways for OSCP1 Gene

No Data Available

Interacting Proteins for OSCP1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: Q8WVF1-OSCP1_HUMAN ENSP00000235532 for OSCP1 Gene via IID STRING

Gene Ontology (GO) - Biological Process for OSCP1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006810 transport IEA --
GO:1903955 positive regulation of protein targeting to mitochondrion IMP 24270810
genes like me logo Genes that share ontologies with OSCP1: view

No data available for Pathways by source and SIGNOR curated interactions for OSCP1 Gene

Drugs & Compounds for OSCP1 Gene

(1) Additional Compounds for OSCP1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • Sodium
  • Sodium ion
genes like me logo Genes that share compounds with OSCP1: view

Transcripts for OSCP1 Gene

Unigene Clusters for OSCP1 Gene

Organic solute carrier partner 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for OSCP1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for OSCP1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b
SP1: - - - - - -
SP2: - - -
SP3: - - - -
SP4: - - - - - -
SP5: - - - - -
SP6: -
SP7: -

Relevant External Links for OSCP1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OSCP1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for OSCP1 Gene

mRNA differential expression in normal tissues according to GTEx for OSCP1 Gene

This gene is overexpressed in Testis (x6.7).

Protein differential expression in normal tissues from HIPED for OSCP1 Gene

This gene is overexpressed in Testis (29.5), Liver, secretome (15.7), and Frontal cortex (7.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for OSCP1 Gene

Protein tissue co-expression partners for OSCP1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of OSCP1 Gene:


SOURCE GeneReport for Unigene cluster for OSCP1 Gene:


mRNA Expression by UniProt/SwissProt for OSCP1 Gene:

Tissue specificity: Expressed predominantly in testis, also found in placenta and to a lesser extent in thymus and small intestine; abundantly expressed in tumor-derived cell lines (PubMed:16006562). Ubiquitously expressed (PubMed:12819961).

Evidence on tissue expression from TISSUES for OSCP1 Gene

  • Nervous system(4.5)
genes like me logo Genes that share expression patterns with OSCP1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for OSCP1 Gene

Orthologs for OSCP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for OSCP1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia OSCP1 34
  • 95 (a)
(Canis familiaris)
Mammalia OSCP1 33 34
  • 89.15 (n)
(Bos Taurus)
Mammalia OSCP1 33 34
  • 88.65 (n)
(Rattus norvegicus)
Mammalia Oscp1 33
  • 86.63 (n)
(Mus musculus)
Mammalia Oscp1 33 16 34
  • 85.49 (n)
(Ornithorhynchus anatinus)
Mammalia OSCP1 34
  • 85 (a)
(Monodelphis domestica)
Mammalia OSCP1 34
  • 75 (a)
(Gallus gallus)
Aves OSCP1 33 34
  • 76.52 (n)
(Anolis carolinensis)
Reptilia OSCP1 34
  • 76 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia oscp1 33
  • 71.06 (n)
Str.15507 33
(Danio rerio)
Actinopterygii OSCP1 (2 of 2) 34
  • 73 (a)
LOC100334608 33
  • 70.36 (n)
oscp1a 34
  • 57 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011836 33
  • 48.96 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG13178 33 34
  • 48.85 (n)
(Caenorhabditis elegans)
Secernentea R10F2.5 33 34
  • 50.53 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 41 (a)
Species where no ortholog for OSCP1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for OSCP1 Gene

Gene Tree for OSCP1 (if available)
Gene Tree for OSCP1 (if available)

Paralogs for OSCP1 Gene

No data available for Paralogs for OSCP1 Gene

Variants for OSCP1 Gene

Sequence variations from dbSNP and Humsavar for OSCP1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000173207 -- 36,430,862(+) GTTGG(C/T)CAGGC intron-variant
rs1000243669 -- 36,441,636(+) AGTCC(C/T)AGCTA intron-variant
rs1000482534 -- 36,428,482(+) TGTAT(A/T)TGCAC intron-variant
rs1000493470 -- 36,427,596(+) ACAGG(C/T)GTGAG intron-variant
rs1000544856 -- 36,421,089(+) TAGCC(C/T)GGCCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OSCP1 Gene

Variant ID Type Subtype PubMed ID
dgv28e212 CNV loss 25503493
esv2758931 CNV loss 17122850
esv3577808 CNV loss 25503493
nsv509202 CNV insertion 20534489

Variation tolerance for OSCP1 Gene

Residual Variation Intolerance Score: 22.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.95; 93.62% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OSCP1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OSCP1 Gene

Disorders for OSCP1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for OSCP1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
pharynx cancer
  • pharyngeal cancer
- elite association - COSMIC cancer census association via MalaCards
Search OSCP1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for OSCP1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with OSCP1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for OSCP1 Gene

Publications for OSCP1 Gene

  1. Cloning, expression, and mutation analysis of NOR1, a novel human gene down-regulated in HNE1 nasopharyngeal carcinoma cell line. (PMID: 12819961) Nie X … Li G (Journal of cancer research and clinical oncology 2003) 3 4 22 60
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 45 60
  3. Preparation of polyclonal antibody specific for NOR1 and detection of its expression pattern in human tissues and nasopharyngeal carcinoma. (PMID: 19727524) Xiang B … Li G (Acta biochimica et biophysica Sinica 2009) 3 22 60
  4. Isolation and functional characterization of a novel organic solute carrier protein, hOSCP1. (PMID: 16006562) Kobayashi Y … Yamamoto T (The Journal of biological chemistry 2005) 3 4 60
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60

Products for OSCP1 Gene

Sources for OSCP1 Gene

Loading form....