Aliases for OSCAR Gene
External Ids for OSCAR Gene
Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex protein family that plays critical roles in the regulation of both innate and adaptive immune responses. The encoded protein may play a role in oxidative stress-mediated atherogenesis as well as monocyte adhesion. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
GeneCards Summary for OSCAR Gene
OSCAR (Osteoclast Associated, Immunoglobulin-Like Receptor) is a Protein Coding gene. Diseases associated with OSCAR include decubitus ulcer. Among its related pathways are Osteoclast differentiation. An important paralog of this gene is KIR2DL4.
UniProtKB/Swiss-Prot for OSCAR Gene
Regulator of osteoclastogenesis which plays an important bone-specific function in osteoclast differentiation.