Aliases for OSBPL5 Gene
External Ids for OSBPL5 Gene
Previous GeneCards Identifiers for OSBPL5 Gene
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
GeneCards Summary for OSBPL5 Gene
OSBPL5 (Oxysterol Binding Protein-Like 5) is a Protein Coding gene. Diseases associated with OSBPL5 include adult syndrome. GO annotations related to this gene include phospholipid binding and oxysterol binding. An important paralog of this gene is OSBPL11.
UniProtKB/Swiss-Prot for OSBPL5 Gene
May cooperate with NPC1 to mediate the exit of cholesterol from endosomes/lysosomes.