Aliases for OSBPL3 Gene
External Ids for OSBPL3 Gene
Previous HGNC Symbols for OSBPL3 Gene
Previous GeneCards Identifiers for OSBPL3 Gene
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. The encoded protein is involved in the regulation of cell adhesion and organization of the actin cytoskeleton. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for OSBPL3 Gene
OSBPL3 (Oxysterol Binding Protein-Like 3) is a Protein Coding gene. Diseases associated with OSBPL3 include simpson-golabi-behmel syndrome. GO annotations related to this gene include cholesterol binding. An important paralog of this gene is OSBP.
UniProtKB/Swiss-Prot for OSBPL3 Gene
Binds 25-hydroxycholesterol and cholesterol.