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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

OSBPL3 Gene

protein-coding GIFtS: 54
GCID: GC07M024836

oxysterol binding protein-like 3

(Previous symbol: OSBP3)

Explore 2 diseases affiliated with
OSBPL3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Oxysterol Binding Protein-Like 3¹ ²		KIAA0704¹ ³ ⁵
ORP3¹ ² ³ ⁵		OSBP-Related Protein 3² ³
ORP-3¹ ² ³		Oxysterol-Binding Protein 3²
OSBP3¹ ² ³		Oxysterol-Binding Protein-Related Protein 3²

External Ids:	HGNC: 16370¹	Entrez Gene: 26031²	Ensembl: ENSG00000070882⁷	OMIM: 606732⁵	UniProtKB: Q9H4L5³

Export aliases for OSBPL3 gene to outside databases

Previous GC identifers: GC07M024478 GC07M024578 GC07M024609 GC07M024804

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for OSBPL3:

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors.

Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like

sterol-binding domain. Several transcript variants encoding different isoforms have been identified. (provided by

RefSeq, Jul 2008)

Gene Wiki entry for OSBPL3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the OSBPL3 gene promoter:
PPAR-gamma1 MEF-2 aMEF-2 PPAR-gamma2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): OSBPL3 promoter sequence

Search SABiosciences Chromatin IP Primers for OSBPL3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSBPL3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15 Ensembl cytogenetic band: 7p15.3 HGNC cytogenetic band: 7p15.3

OSBPL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OSBPL3 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M024836: view genomic region (about GC identifiers)

Start:	24,836,158 bp from pter	End:	25,021,253 bp from pter
Size:	185,096 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 24,887,733-25,071,319

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: OSBL3_HUMAN, Q9H4L5 (See protein sequence)

Recommended Name: Oxysterol-binding protein-related protein 3

Size: 887 amino acids; 101224 Da

Sequence caution: Sequence=BAA31679.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;

Secondary accessions: A4D167 A4D168 A4D169 A4D170 A4D171 A4D172 B8ZZ79 B8ZZP0 O14591 O43357 O43358

Q8N702 Q8N703 Q8N704 Q8NFH0 Q8NFH1 Q8NI12 Q8NI13 Q9BZF4 Q9UED6

Alternative splicing: 8 isoforms: Q9H4L5-1 Q9H4L5-2 Q9H4L5-3 Q9H4L5-4 Q9H4L5-5 Q9H4L5-6 Q9H4L5-7 Q9H4L5-8

(May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for OSBPL3: NX_Q9H4L5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9H4L5

OSBPL3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_056365.1 NP_663160.1 NP_663161.1 NP_663162.1

ENSEMBL proteins:

ENSP00000315410 ENSP00000386429 ENSP00000379708 ENSP00000386801 ENSP00000386325

ENSP00000386990 ENSP00000379706 ENSP00000386953 ENSP00000407829 ENSP00000403374

ENSP00000411249 ENSP00000315331 ENSP00000315277 ENSP00000389779

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	OriGene Purified Proteins (see all 2): OSBPL3 OriGene Protein Over-expression Lysate (see all 4): OSBPL3 OriGene Custom Protein Services for OSBPL3
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	Novus Biologicals OSBPL3 Proteins Novus Biologicals OSBPL3 Lysates
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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for OSBPL3

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005829	cytosol	IDA	14593528
GO:0005886	plasma membrane	IDA	14593528
GO:0031965	nuclear membrane	IDA	14593528
GO:0097038	perinuclear endoplasmic reticulum	IDA	14593528

OSBPL3 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for OSBPL3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

OSBPL3 for domains About GeneDecksing

4 InterPro domains/families:

IPR001849 Pleckstrin_homology

IPR011993 PH_like_dom

IPR000648 Oxysterol-bd

IPR018494 Oxysterol-bd_CS

Graphical View of Domain Structure for InterPro Entry Q9H4L5

ProtoNet protein and cluster: Q9H4L5

2 Blocks protein families:

IPB000648 Oxysterol-binding protein

IPB001849 Pleckstrin-like

UniProtKB/Swiss-Prot: OSBL3_HUMAN, Q9H4L5

Similarity: Belongs to the OSBP family

Similarity: Contains 1 PH domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone (see all 4): OSBPL3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSBPL3
		8/72 QIAGEN miScript miRNA Assays for microRNAs that regulate OSBPL3 (see all 72):
		hsa-miR-579 hsa-miR-300 hsa-miR-3653 hsa-miR-502-3p hsa-miR-1273d hsa-miR-508-5p hsa-miR-3148 hsa-miR-3688-3p

		SwitchGear 3'UTR luciferase reporter plasmid: OSBPL3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OSBPL3 (see all 4) OriGene shRNA RFP: OSBPL3 OriGene siRNA: OSBPL3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSBPL3

Gene Editing
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DNA2.0 Custom Protein Engineering Service for OSBPL3

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		Search LifeMap BioReagents cell lines for OSBPL3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSBPL3

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	--
GO:0005543	phospholipid binding	IEA	--
GO:0015485	cholesterol binding	IDA	17428193

OSBPL3 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for OSBPL3

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5/35 Interacting proteins for OSBPL3 (Q9H4L5^{1, 2, 3} ENSP00000315410⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 35)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAB	P31946²^,³, ENSP00000300161⁴	MINT-50980 I2D: score=4 STRING: ENSP00000300161
YWHAG	P61981²^,³, ENSP00000306330⁴	MINT-50839 I2D: score=4 STRING: ENSP00000306330
SFN	P31947²^,³	MINT-3975507 I2D: score=2
UBC	P0CG48³, ENSP00000344818⁴	I2D: score=1 STRING: ENSP00000344818
YWHAH	Q04917³, ENSP00000248975⁴	I2D: score=1 STRING: ENSP00000248975

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006869	lipid transport	IEA	--

OSBPL3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for OSBPL3
Search CenterWatch for drugs/clinical trials and news about OSBPL3 / OSBL3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for OSBPL3 gene (6 alternative transcripts):

NM_015550.2 NM_145320.1 NM_145321.1 NM_145322.1 NM_145323.1 NM_145324.1

Unigene Cluster for OSBPL3:

Oxysterol binding protein-like 3

Hs.520259 [show with all ESTs]

Unigene Representative Sequence: NM_015550

17 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000313367(uc003sxd.3 uc003sxe.3 uc003sxf.3 uc003sxg.3 uc003sxh.3 uc003sxi.3)

ENST00000409863 ENST00000396431 ENST00000409452 ENST00000409759(uc003sxj.1)

ENST00000487020 ENST00000409555(uc003sxk.1) ENST00000396429 ENST00000409069

ENST00000459987 ENST00000461835 ENST00000415162 ENST00000441059 ENST00000415952

ENST00000352860 ENST00000353930 ENST00000431825

miRNA Products:		OriGene 3'-UTR Clone (see all 4): OSBPL3 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat OSBPL3
		8/72 QIAGEN miScript miRNA Assays for microRNAs that regulate OSBPL3 (see all 72):
		hsa-miR-579 hsa-miR-300 hsa-miR-3653 hsa-miR-502-3p hsa-miR-1273d hsa-miR-508-5p hsa-miR-3148 hsa-miR-3688-3p

		SwitchGear 3'UTR luciferase reporter plasmid: OSBPL3 3' UTR sequence

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		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OSBPL3 (see all 4) OriGene shRNA RFP: OSBPL3 OriGene siRNA: OSBPL3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSBPL3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OSBPL3 (see all 7) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OSBPL3 (see all 5) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSBPL3

Additional cDNA sequence:

AB014604.2 AF323727.1 AF392444.1 AF491781.1 AF491782.1 AF491783.1 AF491784.1 AF515639.1

AF515640.1 AL832293.1 AY008372.1 BC017731.1

15 DOTS entries:

DT.100025959 DT.97770440 DT.100025961 DT.100025955 DT.100025954 DT.111823 DT.121046610 DT.100782233

DT.100025953 DT.91751546 DT.121046633 DT.95373952 DT.91642204 DT.99999772 DT.91944606

24/159 AceView cDNA sequences (see all 159):

AA903465 Z44256 AF515640 AF392444 AA768373 AF491786 CA397144 N35950

AI249926 AI696489 AI147104 AW338540 AF515639 AI217788 AF491785 AF491781

AF491783 BC017731 AA491160 AA490967 AF491784 AW241639 BG261305 AF323727

GeneLoc Exon Structure

5/12 Alternative Splicing Database (ASD) splice patterns (SP) for OSBPL3 (see all 12) About this scheme

ExUns:	1	^	2	^	3a	·	3b	·	3c	^	4	^	5a	·	5b	^	6	^	7a	·	7b	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19a	·	19b	·
SP1:					-		-		-
SP2:																															-								-		-
SP3:																																							-		-
SP4:																																									-
SP5:

ExUns:	19c	·	19d	^	20	^	21	^	22a	·	22b	^	23a	·	23b	^	24	^	25a	·	25b
SP1:
SP2:
SP3:
SP4:
SP5:									-

ECgene alternative splicing isoforms for OSBPL3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

OSBPL3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGAGCACCA

About this image

OSBPL3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Brain

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See OSBPL3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OSBPL3

SOURCE GeneReport for Unigene cluster: Hs.520259

UniProtKB/Swiss-Prot: OSBL3_HUMAN, Q9H4L5

Tissue specificity: Isoform 1a, isoform 1b, isoform 1c and isoform 1d are highly expressed in brain, bone marrow,

colon, kidney, lung, skeletal muscle, spleen, thymus and thyroid. Not expressed in heart and liver. Isoform 2a,

isoform 2b, isoform 2c and isoform 2d are expressed in brain, bone marrow, kidney, skeletal muscle, spleen, thymus and

thyroid. Not expressed in heart, liver and lung

SABiosciences Custom PCR Arrays for OSBPL3

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSBPL3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSBPL3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for OSBPL3 gene from 4/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	OSBPL3¹	oxysterol binding protein-like 3	76.41(n) 80.14(a)		428432 XM_425992.2 XP_425992.2
lizard (Anolis carolinensis)	Reptilia	OSBPL3⁶	--	79(a)	1 ↔ 1	6(31172749-31224056)
zebrafish (Danio rerio)	Actinopterygii	Dr.24867²	Transcribed sequence with weak similarity to protein more	75.54(n)		BM184372.1
rice (Oryza sativa)	Liliopsida	Os.35068²	Oryza sativa (japonica cultivar-group) cDNA cloneJ more	72.08(n)		AK069104.1

ENSEMBL Gene Tree for OSBPL3 (if available)
TreeFam Gene Tree for OSBPL3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for OSBPL3 gene

OSBP² OSBPL1A² OSBPL7² OSBP2² OSBPL2² OSBPL6²

2 SIMAP similar genes for OSBPL3 using alignment to 4 protein entries: OSBL3_HUMAN (see all proteins):

OSBPL6 OSBPL7

OSBPL3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs76881352^1,2	C,	--	24835729(+)	`GGGCTA/GTTAGT`	4	--	ds500¹		3		NA EA	242
rs76578010^1,2	F,	--	24835781(+)	`ACTGCA/GTGGGG`	4	--	ds500¹		1		WA	118
rs2106760^1,2	C,F,A,H,	--	24835787(+)	`TGGGGT/CATTGG`	4	--	ds500¹		23		NS EA NA WA CSA	2340
rs181981155^1,2		--	24835827(+)	`CAACCA/GTAATA`	4	--	ds500¹		0	--	--	--	--
rs73088325^1,2	C,F,	--	24836133(+)	`TTAACC/GTGGAA`	4	--	ds500¹		2		WA NA	238
rs79107368^1,2	C,	--	24836244(+)	`AGAGGG/TATGGA`	4	--	ut3¹		0	--	--	--	--
rs145654343^1,2		--	24836604(+)	`GCCAAA/TACATT`	4	--	ut3¹		0	--	--	--	--
rs183655880^1,2		--	24836936(+)	`TATATC/TAGTTT`	4	--	ut3¹		0	--	--	--	--
rs188407522^1,2		--	24837055(+)	`ACCAGA/TATCCA`	4	--	ut3¹		0	--	--	--	--
rs181198943^1,2		--	24837224(+)	`ATGGAC/TTTCCT`	4	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for OSBPL3 (24836158 - 25021253 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for OSBPL3
1 Indel: 69830

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OSBPL3

DNA2.0 Custom Variant and Variant Library Synthesis for OSBPL3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OSBPL3 for disorders           About GeneDecksing

OMIM gene information: 606732    OMIM disorders: --

2 diseases for OSBPL3:    About MalaCards

thyroiditis malaria

Human Genome Epidemiology (HuGE) Navigator: OSBPL3 (2 documents)

Export disorders for OSBPL3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for OSBPL3 gene, integrated from 9 sources (see all 31):
(articles sorted by number of sources associating them with OSBPL3)

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Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)^{1, 2, 3} Ishikawa K.... Ohara O. (1998)
ORP3 splice variants and their expression in human tissues and hematopoietic cells. (PubMed id 12590732)^{1, 2, 9} Collier F.M....Kirkland M.A. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)^{1, 2} Scherer S.W.... Tsui L.-C. (2003)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
ORP-3, a human oxysterol-binding protein gene differentially expressed in hematopoietic cells. (PubMed id 11568019)^{1, 2} Gregorio-King C.C.... Kirkland M.A. (2001)
A family of 12 human genes containing oxysterol-binding domains. (PubMed id 11735225)^{1, 2} Jaworski C.J.... Rodriguez I.R. (2001)
The OSBP-related protein family in humans. (PubMed id 11483621)^{1, 2} Lehto M.... Olkkonen V.M. (2001)
Targeting of OSBP-related protein 3 (ORP3) to endoplasmic reticulum and plasma membrane is controlled by multiple determinants. (PubMed id 16143324)^{1, 9} Lehto M....Olkkonen V.M. (2005)
The R-Ras interaction partner ORP3 regulates cell adhesion. (PubMed id 18270267)^{1, 9} Lehto M....Olkkonen V.M. (2008)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 26031	HGNC: 16370	AceView: OSBPL3	Ensembl:ENSG00000070882	euGenes: HUgn26031
ECgene: OSBPL3	H-InvDB: OSBPL3

(According to HUGE)
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HUGE: KIAA0704

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for OSBPL3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for OSBPL3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for OSBPL3 gene:
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GeneCards and IP:
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OSBPL3 Gene

oxysterol binding protein-like 3

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OSBPL3 Gene

oxysterol binding protein-like 3

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