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OSBPL10 Gene

protein-coding   GIFtS: 52
GCID: GC03M031677

Oxysterol Binding Protein-Like 10

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Oxysterol Binding Protein-Like 101 2
ORP102 3 5
ORP-102 3
OSBP92 3
OSBP-Related Protein 102 3
Oxysterol-Binding Protein-Related Protein 102

External Ids:    HGNC: 163951   Entrez Gene: 1148842   Ensembl: ENSG000001446457   OMIM: 6067385   UniProtKB: Q9BXB53   

Export aliases for OSBPL10 gene to outside databases

Previous GC identifers: GC03M031290 GC03M031071 GC03M031548 GC03M031674


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for OSBPL10 Gene:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid
receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly
conserved C-terminal OSBP-like sterol-binding domain. Multiple transcript variants encoding different isoforms
have been found for this gene. (provided by RefSeq, Mar 2010)

GeneCards Summary for OSBPL10 Gene:
OSBPL10 (oxysterol binding protein-like 10) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and cholesterol binding. An important paralog of this gene is OSBPL9.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000003.11  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the OSBPL10 gene promoter:
         E2F-4   E2F-3a   AREB6   E2F-5   E2F-1   E2F   E2F-2   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): OSBPL10 promoter sequence
   Search Chromatin IP Primers for OSBPL10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat OSBPL10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.3   Ensembl cytogenetic band:  3p22.3   HGNC cytogenetic band: 3p23

OSBPL10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
OSBPL10 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M031677:  view genomic region     (about GC identifiers)

Start:
31,699,382 bp from pter      End:
32,119,072 bp from pter
Size:
419,691 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: OSB10_HUMAN, Q9BXB5 (See protein sequence)
Recommended Name: Oxysterol-binding protein-related protein 10  
Size: 764 amino acids; 83970 Da
Secondary accessions: B4E212 Q9BTU5
Alternative splicing: 2 isoforms:  Q9BXB5-1   Q9BXB5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for OSBPL10: NX_Q9BXB5

Explore proteomics data for OSBPL10 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys425
  • Modification sites at PhosphoSitePlus

  • See OSBPL10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001167531.1  NP_060254.2  

    ENSEMBL proteins: 
     ENSP00000379804   ENSP00000416078   ENSP00000406124   ENSP00000399200  

    OSBPL10 Human Recombinant Protein Products:

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    Novus Biologicals OSBPL10 Protein
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for OSBPL10

     
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    antibodies-online proteins for OSBPL10 (3 products) 

     
    antibodies-online peptides for OSBPL10

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    antibodies-online antibodies for OSBPL10 (22 products) 

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    antibodies-online kits for OSBPL10 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    OSBP: Oxysterol binding proteins
    PLEKH: Pleckstrin homology (PH) domain containing

    4 InterPro protein domains:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR000648 Oxysterol-bd
     IPR018494 Oxysterol-bd_CS

    Graphical View of Domain Structure for InterPro Entry Q9BXB5

    ProtoNet protein and cluster: Q9BXB5

    2 Blocks protein domains:
    IPB000648 Oxysterol-binding protein
    IPB001849 Pleckstrin-like


    UniProtKB/Swiss-Prot: OSB10_HUMAN, Q9BXB5
    Similarity: Belongs to the OSBP family
    Similarity: Contains 1 PH domain


    Find genes that share domains with OSBPL10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015485cholesterol binding IDA17428193
         
    Find genes that share ontologies with OSBPL10           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for OSBPL10
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for OSBPL10

    miRNA
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    miRTarBase miRNAs that target OSBPL10:
    hsa-let-7b-5p (MIRT032294), hsa-mir-215-5p (MIRT024715), hsa-mir-1 (MIRT023671), hsa-mir-155-5p (MIRT020572), hsa-mir-98-5p (MIRT027577), hsa-mir-192-5p (MIRT026342), hsa-mir-222-3p (MIRT046716)

    Block miRNA regulation of human, mouse, rat OSBPL10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OSBPL10 (see all 29):
    hsa-miR-3685 hsa-miR-520d-5p hsa-miR-128 hsa-miR-1271 hsa-miR-3653 hsa-miR-124 hsa-miR-3658 hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidOSBPL10 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for OSBPL10
    Predesigned siRNA for gene silencing in human, mouse, rat OSBPL10

    Gene Editing
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    Clone
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    OriGene clones in human, mouse for OSBPL10 (see all 9)
    OriGene ORF clones in mouse, rat for OSBPL10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): OSBPL10 (NM_017784)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OSBPL10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSBPL10

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSBPL10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    golgi apparatus1
    nucleus1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for OSBPL10
    Interactions:

        Search GeneGlobe Interaction Network for OSBPL10

    Selected Interacting proteins for OSBPL10 (Q9BXB53) via UniProtKB, MINT, STRING, and/or I2D (see all 17)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALDOAP040753I2D: score=2 
    AP2B1P630103I2D: score=2 
    CLINT1Q146773I2D: score=2 
    CLPBQ9H0783I2D: score=2 
    CUL1Q136163I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006869lipid transport IEA--

    Find genes that share ontologies with OSBPL10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for OSBPL10 (OSB10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for OSBPL10 gene (2 alternative transcripts): 
    NM_001174060.1  NM_017784.4  

    Unigene Cluster for OSBPL10:

    Oxysterol binding protein-like 10
    Hs.150122  [show with all ESTs]
    Unigene Representative Sequence: NM_017784
    18 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396556(uc021wuu.1 uc011axf.2) ENST00000429492(uc003ceu.1)
    ENST00000438237 ENST00000469557 ENST00000467598 ENST00000472175 ENST00000479396
    ENST00000490009 ENST00000467647 ENST00000428241 ENST00000480671 ENST00000485205
    ENST00000467955 ENST00000466604 ENST00000463504 ENST00000479173 ENST00000452791
    ENST00000465626
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat OSBPL10 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate OSBPL10 (see all 29):
    hsa-miR-3685 hsa-miR-520d-5p hsa-miR-128 hsa-miR-1271 hsa-miR-3653 hsa-miR-124 hsa-miR-3658 hsa-miR-889
    SwitchGear 3'UTR luciferase reporter plasmidOSBPL10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for OSBPL10
    Predesigned siRNA for gene silencing in human, mouse, rat OSBPL10
    Clone
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    OriGene clones in human, mouse for OSBPL10 (see all 9)
    OriGene ORF clones in mouse, rat for OSBPL10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): OSBPL10 (NM_017784)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for OSBPL10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSBPL10
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for OSBPL10
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat OSBPL10
      QuantiTect SYBR Green Assays in human, mouse, rat OSBPL10
      QuantiFast Probe-based Assays in human, mouse, rat OSBPL10

    Additional mRNA sequence: 

    AF346291.1 AF392451.1 AK000370.1 AK304067.1 BC003168.1 

    12 DOTS entries:

    DT.455472  DT.100746955  DT.40223614  DT.91726235  DT.120884379  DT.95295142  DT.75130711  DT.91867719 
    DT.95114461  DT.95295110  DT.97860581  DT.97816288 

    Selected AceView cDNA sequences (see all 164):

    CR604343 AA952982 AI348691 AI968590 BQ024207 BU618574 BX118507 BF062381 
    AA732641 CA418841 AW006259 AW241559 BF109458 AI655630 AA577446 AL389943 
    BM479166 BM463121 AW593467 NM_017784 AA810245 BE303047 AW269415 AI394567 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for OSBPL10 (see all 12)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^
    SP1:              -     -     -           -     -                             -                                         -     -     -                           
    SP2:                          -           -     -                             -                                                                                 
    SP3:                                                                          -                                                                                 
    SP4:                                                                          -                                                                                 
    SP5:                                                                                                                                                            

    ExUns: 17 ^ 18 ^ 19a · 19b ^ 20a · 20b
    SP1:              -                     
    SP2:                                    
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for OSBPL10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    OSBPL10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    OSBPL10 Expression
    About this image


    OSBPL10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
             Human embryonic stem cells (family)
     
     Neurons
             Midbrain dopaminergic-like neurons
     
     Blood (Hematopoietic System)
             Mature B-Cells Peripheral Blood
     
     Brain (Nervous System)
             Midbrain dopaminergic-like neurons
     
     Testis (Reproductive System)
    OSBPL10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    OSBPL10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.150122
        Custom PCR Arrays for OSBPL10
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSBPL10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for OSBPL10 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Osbpl101 , 5 oxysterol binding protein-like 101, 5 86.97(n)1
    90.52(a)1
      9 (66.84 cM)5
    744861  NM_148958.21  NP_683761.11 
     1149785695 
    chicken
    (Gallus gallus)
    Aves OSBPL101 oxysterol binding protein-like 10 74.56(n)
    77.98(a)
      420663  XM_004939425.1  XP_004939482.1 
    lizard
    (Anolis carolinensis)
    Reptilia OSBPL106
    oxysterol binding protein-like 10
    72(a)
    1 ↔ 1
    1(193738708-193847721)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia osbpl101 oxysterol binding protein-like 10 69.13(n)
    72.5(a)
      100496082  XM_002941816.2  XP_002941862.1 
    zebrafish
    (Danio rerio)
    Actinopterygii 570968662   -- 77.88(n)    57096866 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG92056
    --
    38(a)
    1 → many
    3L(1034697-1036298)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes OSH76
    OSH66
    Member of an oxysterol-binding protein family with...
    Member of an oxysterol-binding protein family with...
    30(a)
    27(a)
    many ↔ many
    many ↔ many
    VIII(106055-107368) YHR001W
    XI(445381-446727) YKR003W


    ENSEMBL Gene Tree for OSBPL10 (if available)
    TreeFam Gene Tree for OSBPL10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for OSBPL10 gene
    OSBPL92  OSBPL52  OSBPL82  OSBPL112  
    3 SIMAP similar genes for OSBPL10 using alignment to 3 protein entries:     OSB10_HUMAN (see all proteins):
    pp14733    OSBPL11    OSBPL9

    Find genes that share paralogs with OSBPL10           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for OSBPL10 (see all 6885)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1502908561,2
    --31701954(+) CTTTTC/TCTCAA 2 -- ds50010--------
    rs105765311,2
    C--31701979(+) CACTT-/TCTCTGT 2 -- ds50011Minor allele frequency- TC:0.50CSA 2
    rs584014521,2
    C--31701980(+) TTTCT-/CTGTCAG 2 -- ds50010--------
    rs1995052081,2
    C--31701980(-) ACAGAA/GAAAGT 2 -- ds50010--------
    rs1852675841,2
    --31702050(+) AAGTAA/GGCTTC 2 -- ds50010--------
    rs1896007631,2
    --31702156(+) GTTTAC/TCTGGT 2 -- ds50010--------
    rs1379469241,2
    --31702205(+) ATGATC/TGCTCT 2 -- ds50010--------
    rs1144851821,2
    F--31702493(+) ACCAGA/GTATTT 2 -- ut311Minor allele frequency- G:0.01WA 118
    rs2007008191,2
    --31702704(+) CAAAC-/TTAAAT 2 -- ut310--------
    rs775796351,2
    F--31702826(+) GTAAAA/GGAAGC 2 -- ut311Minor allele frequency- G:0.01NA 120

    HapMap Linkage Disequilibrium report for OSBPL10 (31699382 - 31949382 bp, first 250kb of OSBPL10)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for OSBPL10 (see all 27):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1288233CNV Deletion17803354
    esv2725098CNV Deletion23290073
    esv988249CNV Deletion20482838
    esv2725095CNV Deletion23290073
    esv2725097CNV Deletion23290073
    esv2725101CNV Deletion23290073
    esv1213497CNV Deletion17803354
    esv2725099CNV Deletion23290073
    esv2725100CNV Deletion23290073
    esv1005278CNV Deletion20482838

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606738    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for OSBPL10:
    Familial combined hyperlipidemia

    Find genes that share disorders with OSBPL10           About GenesLikeMe

    Genetic Association Database (GAD): OSBPL10
    Human Genome Epidemiology (HuGE) Navigator: OSBPL10 (4 documents)

    Export disorders for OSBPL10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for OSBPL10 gene, integrated from 10 sources (see all 27):
    (articles sorted by number of sources associating them with OSBPL10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism. (PubMed id 19554302)1, 4, 9 PerttilAo J....Olkkonen V.M. (J. Mol. Med. 2009)
    2. Variation in OSBPL10 is associated with dyslipidemia. (PubMed id 20224571)1, 4, 9 Koriyama H....Rakugi H. (Hypertens. Res. 2010)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population. (PubMed id 20610895)1, 4 Koriyama H....Morishita R. (J. Atheroscler. Thromb. 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A family of 12 human genes containing oxysterol-binding domains. (PubMed id 11735225)1, 2 Jaworski C.J.... Rodriguez I.R. (Genomics 2001)
    7. The OSBP-related protein family in humans. (PubMed id 11483621)1, 2 Lehto M.... Olkkonen V.M. (J. Lipid Res. 2001)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    9. ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion. (PubMed id 22906437)1 NissilAo E....Olkkonen V.M. (Biochim. Biophys. Acta 2012)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 114884 HGNC: 16395 AceView: OSBPL10 Ensembl:ENSG00000144645 euGenes: HUgn114884
    ECgene: OSBPL10 H-InvDB: OSBPL10

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for OSBPL10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for OSBPL10 gene:
    Search GeneIP for patents involving OSBPL10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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