OSBP Gene
protein-coding GIFtS: 57
GCID: GC11M059341
|
|
oxysterol binding protein
| |
Aliases
for OSBP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Oxysterol Binding Protein1 2 | | OSBP11 2 3 | | Oxysterol-Binding Protein 12 |
Export aliases for OSBP gene to outside databasesPrevious GC identifers: GC11M061735 GC11M060855 GC11M059592 GC11M059117 GC11M059098 GC11M055689 |
Summaries
for OSBP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for OSBP:
Oxysterol binding protein is an intracellular protein that is believed to transport sterols from lysosomes to thenucleus where the sterol down-regulates the genes for the LDL receptor, HMG-CoA reductase, and HMG synthetase(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: OSBP1_HUMAN, P22059Function: Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex withPP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25-hydroxycholesterol causes its disassembly.Regulates cholesterol efflux by decreasing ABCA1 stability
Gene Wiki entry for OSBP
|
Genomic Views
for OSBP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the OSBP gene promoter:
Bach1 CBF-C MEF-2A CBF-B CBF-A aMEF-2 CP1A Zic3 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for OSBP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSBP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q12-q13 Ensembl cytogenetic band: 11q12.1 HGNC cytogenetic band: 11q12-q13OSBP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M059341: view genomic region
(about GC identifiers)
Start:
|
59,341,871 bp from pter |
End:
|
59,383,617 bp from pter |
Size:
|
41,747 bases |
Orientation:
|
minus strand |
|
Proteins
for OSBP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: OSBP1_HUMAN, P22059 (See
protein sequence)Recommended Name: Oxysterol-binding protein 1 Size: 807 amino acids; 89421 Da
Subunit: Homodimer or homotrimer. Interacts with VAPA
Subcellular location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Note=When bound to oxysterols,translocates to the periphery of Golgi membranes
Sequence caution: Sequence=AAH63121.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing;
1 PDB 3D structure from  and Proteopedia  for OSBP:2RR3 (3D)
Secondary accessions: Q6P524Explore the universe of human proteins at neXtProt for OSBP: NX_P22059
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P22059
OSBP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_002547.1
ENSEMBL proteins: ENSP00000263847 ENSP00000432399
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000139 | Golgi membrane |
IEA | -- |
OSBP for ontologies About GeneDecksing
OSBP Antibody Products:
Assay Products for OSBP: |
Protein
Domains /
Families
for OSBP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
OSBP for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P22059ProtoNet protein and cluster: P22059 2 Blocks protein families: IPB000648 Oxysterol-binding protein IPB001849 Pleckstrin-like
UniProtKB/Swiss-Prot: OSBP1_HUMAN, P22059Domain: The PH and Ala/Gly-rich domains control cholesterol binding without affecting 25-hydroxycholesterol binding (Bysimilarity)Domain: The second coiled-coil domain is required for interaction with the tyrosine phosphatase (By similarity)Similarity: Belongs to the OSBP familySimilarity: Contains 1 PH domain |
Function
for OSBP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: OSBP1_HUMAN, P22059Function: Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex withPP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25-hydroxycholesterol causes its disassembly.Regulates cholesterol efflux by decreasing ABCA1 stability Genatlas biochemistry entry for OSBP:oxysterol binding protein,involved in the regulation of cholesterol metabolism
Clone
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OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OSBP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for OSBP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSBP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSBP |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
OSBP for ontologies About GeneDecksing
|
Pathways & Interactions
for OSBP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for OSBP
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/45 Interacting proteins for OSBP (P220593 ENSP000002638474) via UniProtKB, MINT, STRING, and/or I2D (see all 45)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006869 | lipid transport |
IEA | -- |
OSBP for ontologies About GeneDecksing
|
Drugs & Compounds
for OSBP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
OSBP for compounds About GeneDecksing
 Browse Tocris compounds for OSBP
1 HMDB Compound for OSBP About this table
9 Novoseek chemical compound relationships for OSBP gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| 25-hydroxycholesterol |
90.2 |
27 |
16098143 (6), 9337870 (3), 8217873 (2), 18165705 (2) (see all 10) |
| sterol |
77.9 |
33 |
19129476 (3), 19207211 (3), 16876994 (2), 16571669 (2) (see all 12) |
| cholesterol |
64 |
47 |
9337870 (5), 15746430 (5), 16098143 (4), 18165705 (4) (see all 17) |
| 3-hydroxy-3-methylglutaryl-coa |
53 |
1 |
10364480 (1) |
| lipid |
52 |
19 |
15166789 (2), 20224571 (1), 18614794 (1), 15746430 (1) (see all 12) |
| ceramide |
48.7 |
11 |
16571669 (5), 19129476 (1), 15907394 (1), 16806880 (1) |
| phosphatidylinositol |
38.8 |
4 |
15635101 (1), 18614794 (1), 9268346 (1) |
| phosphatidylcholine |
21.3 |
1 |
18614794 (1) |
| tyrosine |
0 |
1 |
15746430 (1) |
Search CenterWatch for drugs/clinical trials and news about OSBP / OSBP1
|
Transcripts
for OSBP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for OSBP gene: NM_002556.2 Unigene Cluster for OSBP: Oxysterol binding protein Hs.597091 [show with all ESTs]Unigene Representative Sequence: AF1856963 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000263847(uc009ymr.1 uc001noc.1) ENST00000525357 ENST00000528903
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OSBP (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OSBP
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: OSBP (NM_002556) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for OSBP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSBP |
Additional cDNA sequence: AF185696.1 AK299071.1 AK310538.1 BC011581.1 BC017975.1 BC051350.1 BC063121.1 M86917.1 7 DOTS entries: DT.416931 DT.92414555 DT.95278062 DT.100823830 DT.95176337 DT.120713158 DT.422599 24/299 AceView cDNA sequences (see all 299): BX496348 BU618934 AA364216 BQ687533 BQ682579 BF062656 BX952624 AA494294 AA489186 AA836377 N76833 BM799300 AW026221 NM_002556 CR624389 AW949418 BM989209 CB134587 AW298003 AW052144 M86917 BC051350 AF185696 BM720513
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for OSBP About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for OSBP
|
Expression
for OSBP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| OSBP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAAACAAAAC
About this image
See OSBP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for OSBP
SOURCE GeneReport for Unigene cluster: Hs.597091
UniProtKB/Swiss-Prot: OSBP1_HUMAN, P22059Tissue specificity: Widely expressed
SABiosciences Custom PCR Arrays for OSBP
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OSBP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat OSBP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSBP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSBP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSBP |
Orthologs
for OSBP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for OSBP gene from 9/32 species (see all 32) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
OSBP1 |
oxysterol binding protein |
78.15(n)
91.09(a) |
|
426566 XM_424206.3 XP_424206.3 |
lizard
(Anolis carolinensis) |
Reptilia |
OSBP6 |
-- |
90(a) |
1 ↔ 1 |
1(91002190-91041816) |
African clawed frog
(Xenopus laevis) |
Amphibia |
BQ734939.12 |
-- |
75.84(n) |
|
BQ734939.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
osbp1 |
oxysterol binding protein |
68.32(n)
75.41(a) |
|
564372 NM_001145585.1 NP_001139057.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Osbp3 |
oxysterol binding |
45(a) |
|
96B10 -- |
worm
(Caenorhabditis elegans) |
Secernentea |
Y47D3A.17a3 |
-- |
46(a)
(best of 2) |
|
III(11329152-11342496) -- |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
SWH1(YAR042W)4
SWH11 |
Protein similar to mammalian oxysterol-binding protein; more4
Swh1p1 |
47.23(n)1
36.68(a)1 |
|
1(192619-196185)4
8512861, 4 NP_009421.31, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ORP1D1 |
oxysterol binding protein-related protein 1D |
45.74(n)
36.28(a) |
|
837875 NM_001198051.1 NP_001184980.1 |
rice
(Oryza sativa) |
Liliopsida |
Os12g02856001 |
hypothetical protein |
45.27(n)
36.56(a) |
|
4351995 NM_001073118.1 NP_001066586.1 |
ENSEMBL Gene Tree for OSBP (if available)
TreeFam Gene Tree for OSBP (if available) |
Paralogs
for OSBP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for OSBP gene
- OSBPL1A2 OSBPL32 OSBPL72 OSBP22 OSBPL22 OSBPL62
2 SIMAP similar genes for OSBP using alignment to 2 protein entries: OSBP1_HUMAN (see all proteins):OSBP2 OSBPL1A
OSBP for paralogs About GeneDecksing
|
Genomic Variants
for OSBP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for OSBP (59341871 - 59383617 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for OSBP
1 CNV: 85808
1 Indel: 71336 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OSBP |
|
Disorders
/ Diseases
for OSBP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
OSBP for disorders About GeneDecksing
OMIM gene information: 167040
OMIM disorders: --
10  diseases for OSBP: About MalaCardschronic myeloid leukemia myeloid leukemia hepatitis c atherosclerosis
leukemia hepatitis obesity hypertension
cholesterol malaria
2 Novoseek disease relationships for OSBP gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| solid tumor |
16.9 |
1 |
11295104 (1) |
| atherosclerosis |
0 |
1 |
15768828 (1) |
Human Genome Epidemiology (HuGE) Navigator: OSBP (5 documents)
Export disorders for OSBP gene to outside databases
|
Publications
for OSBP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for OSBP gene, integrated from 9 sources (see all 96):
(articles sorted by number of sources associating them with OSBP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19. (PubMed id 1970801)1, 2, 9 Levanon D.... Goldstein J.L. (1990)
- OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation. (PubMed id 15746430)1, 2, 9 Wang P.-Y.... Anderson R.G.W. (2005)
- Electrostatic interaction between oxysterol-binding p rotein and VAMP-associated protein A revealed by NMR and mutagenesis studies. (PubMed id 20178991)1, 2, 9 Furuita K....Kojima C. (2010)
- Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina. (PubMed id 11278871)1, 2, 9 Moreira E.F....Rodriguez I.R. (2001)
- Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Oxysterol-binding protein and vesicle-associated membrane protein-associated protein are required for sterol-dependent activation of the ceramide transport protein. (PubMed id 16571669)1, 9 Perry R.J. and Ridgway N.D. (2006)
- Family of human oxysterol binding protein (OSBP) homologues. A novel member implicated in brain sterol metabolism. (PubMed id 10588946)1, 9 Laitinen S....Ikonen E. (1999)
- The N terminus controls sterol binding while the C terminus regulates the scaffolding function of OSBP. (PubMed id 18165705)1, 9 Wang P.Y....Anderson R.G. (2008)
- A family of 12 human genes containing oxysterol-binding domains. (PubMed id 11735225)1, 9 Jaworski C.J.... Rodriguez I.R. (2001)
|
External Searches for OSBP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing OSBP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing OSBP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing OSBP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for OSBP | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for OSBP gene:
Search GeneIP for patents involving OSBP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for OSBP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
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| | |  | OriGene Antibodies for OSBP | | OriGene shRNA RFP for OSBP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for OSBP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for OSBP | | | OriGene Protein Over-expression Lysate for OSBP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for OSBP | | OriGene 3'-UTR Clone for OSBP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for OSBP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for OSBP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for OSBP | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for OSBP | | OriGene Custom Protein Services for OSBP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat OSBP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing OSBP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat OSBP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat OSBP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat OSBP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat OSBP |
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| | | | Search Tocris compounds for OSBP |
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 | | | OSBP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for OSBP |
|  |  |  | | | | ThermoFisher Antibodies for OSBP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat OSBP |
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