Aliases for ORM1 Gene
External Ids for ORM1 Gene
Previous GeneCards Identifiers for ORM1 Gene
This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]
GeneCards Summary for ORM1 Gene
ORM1 (Orosomucoid 1) is a Protein Coding gene. Diseases associated with ORM1 include Dry Eye Syndrome and Pediatric Multiple Sclerosis. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. An important paralog of this gene is ORM2.
UniProtKB/Swiss-Prot for ORM1 Gene
Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.