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ORC2L Gene

protein-coding GIFtS: 63

GC02M201483

origin recognition complex, subunit 2-like (yeast)
(Previous names: origin recognition complex, subunit 2 (yeast homolog)-like )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
ORC2 ^², ³

Descriptions
origin of replication 2-like ^²
origin recognition complex protein 2 homolog ^²
origin recognition complex, subunit 2 ^²
origin recognition complex, subunit 2 (yeast homolog)-like ^¹
origin recognition complex, subunit 2-like (yeast) ^²

External Ids
HGNC: 8488¹
Entrez Gene: 4999²
UniProtKB: Q13416³
Ensembl: ENSG00000115942⁷

Search outside databases for aliases for ORC2L gene

Previous GC identifers: GC02M199991 GC02M200499 GC02M201738 GC02M201977 GC02M201600

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for ORC2L:

The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential

for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that

ORC binds specifically to origins of replication and serves as a platform for the assembly of

additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a

subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also

interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of

DNA replication. This protein has been demonstrated to specifically associate with the origin of

replication of Epstein-Barr virus in human cells, and is thought to be required for DNA

replication from viral origin of replication. [provided by RefSeq]

UniProtKB/Swiss-Prot: ORC2_HUMAN, Q13416

Function: Component of the origin recognition complex (ORC) that binds origins of replication. It

has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the

ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner

Gene Wiki entry for ORC2L

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ORC2L gene

Entrez Gene cytogenetic band: 2q33 Ensembl cytogenetic band: 2q33.1 HGNC cytogenetic band: 2q33

ORC2L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02M201483: (about GC identifiers)

Start:	201,483,139 bp from pter
End:	201,536,655 bp from pter
Size:	53,517 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000002.10 NT_005403.16

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: ORC2_HUMAN, Q13416 (See protein sequence)

Recommended Name: Origin recognition complex subunit 2

Size: 577 amino acids; 65972 Da

Subunit: ORC is composed of six subunits. Interacts with DBF4 (By similarity). Interacts with MCM10

Subcellular location: Nucleus

Secondary accessions: Q13204

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_006181.1

ENSEMBL proteins:

ENSP00000234296 ENSP00000386390

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ORC2)
	Human Recombinant Proteins from Abnova (ORC2L)

OriGene Purified Recombinant Human Protein: ORC2L

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000808	origin recognition complex	IEA	--
GO:0005634	nucleus	TAS	8808289
GO:0005654	nucleoplasm	EXP	10436018 11095689 11125146 11931757 12045100 15226314 15684404 15707391

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Antibodies for ORC2L:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of ORC2L
	Sigma-Aldrich Antibodies for ORC2L
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for ORC2L (ORC2)
	Antibodies from Abcam (ORC2), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ORC2L)
	Novus Biologicals Antibodies for ORC2L

Assays for ORC2L:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q13416

ProtoNet protein and cluster: Q13416

1 Blocks protein family: IPB007220 Origin recognition complex subunit 2

UniProtKB/Swiss-Prot: ORC2_HUMAN, Q13416

Similarity: Belongs to the ORC2 family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ORC2L)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ORC2L)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006190

Applied Biosystems Silencer® siRNAs for ORC2L

Sigma-Aldrich siRNA for ORC2L

Sigma-Aldrich shRNA for ORC2L

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_006190
Myc/DDK tagged cDNA clone in CMV expression vector: NM_006190
untagged cDNA clone in CMV expression vector: NM_006190

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_006190

UniProtKB/Swiss-Prot: ORC2_HUMAN, Q13416

Function: Component of the origin recognition complex (ORC) that binds origins of replication. It

has a role in both chromosomal replication and mating type transcriptional silencing. Binds to the

ARS consensus sequence (ACS) of origins of replication in an ATP-dependent manner

Genatlas biochemistry entry for ORC2L:

homolog yeast origin of replication recognition complex,subunit ORC2-like,regulator of the

initiation of DNA replication and transcription

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003688	DNA replication origin binding	TAS	8808289
GO:0005515	protein binding	IPI	11095689

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for ORC2L

5/62 Interacting proteins for ORC2L (ENSP00000234296³ Q13416^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 62 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CDC5L	Q99459¹	STRING (score=.998) EBI-374957, EBI-374880
MCM10	Q7L590¹	STRING (score=.999) EBI-374957, EBI-374912
MCM2	P49736¹	STRING (score=.999) EBI-374957, EBI-374819
MCM3	P25205¹	STRING (score=.999) EBI-374957, EBI-355153
ORC1L	Q13415¹	STRING (score=.999) EBI-374957, EBI-374847

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	TAS	8808289
GO:0006260	DNA replication	IEA	--
GO:0006270	DNA replication initiation	TAS	8808289

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ORC2L
1 Novoseek chemical compound relationship for ORC2L gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
lysine	20.66	1	12807890 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ORC2L)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ORC2L)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_006190

Sigma-Aldrich siRNA for ORC2L

Sigma-Aldrich shRNA for ORC2L

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_006190

REFSEQ mRNAs for ORC2L gene:

NM_006190.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_006190

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_006190
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_006190
                                 untagged cDNA clone in CMV expression vector: NM_006190

Additional cDNA sequence:

AK302614.1 AK316433.1 BC014834.1 CR596826.1 U27459.1 U40268.2

13 DOTS entries:

DT.311834 DT.100730274 DT.100780158 DT.311835 DT.91819810 DT.95225732 DT.100780159 DT.120963437

DT.306161 DT.40122280 DT.75122760 DT.95269944 DT.120963364

24/125 AceView cDNA sequences (see all 125 ):

BQ003777 AU130158 AI814392 BU685377 BM834055 BU182508 BC014834 AW085682

AI890085 U40268 AW472983 NM_006190 AW473208 AW004830 BF445652 BQ775398

BM470184 AI805763 CR596826 CF552296 BP353154 BP367458 BM750483 CB136785

highest scoring ESTs for ORC2L:

U27459 AL602737 AU130158 AW672939 BC014834 BG702866 BG719044 BI561185 BM470184 BM560290

Unigene Cluster for ORC2L:

Origin recognition complex, subunit 2-like (yeast)

Hs.444870 [show with all ESTs]

Unigene Representative Sequence: NM_006190

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for ORC2L

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18a	·	18b	^	19a	·	19b
SP1:													-																								-
SP2:
SP3:							-						-
SP4:

About this scheme

ECgene alternative splicing isoforms for ORC2L

2 Ensembl transcripts including schematic representations:

ENST00000234296 ENST00000410039

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ORC2L expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ORC2L

¹ / ² / ³

4 probe-sets matching ORC2L gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
39943_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	U27459	1.00	1.00	1.00	1
204853_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_006190	0.60	1.00	0.82	1
204853_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
1562579_at*²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks ORC2L for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: --

SOURCE GeneReport for Unigene cluster: Hs.444870
Expression variation in blood from EXPOLDB for ORC2L

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for ORC2L gene from 5/18 species (see all 18 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ORC2L¹	--	origin recognition complex, subunit 2-like (yeast)	91.9(n) 91.84(a)	478868 XM_536028.2 XP_536028.1
chimpanzee (Pan troglodytes)	ORC2L¹	--	origin recognition complex, subunit 2-like (yeast)	99.51(n) 99.08(a)	459868 XM_516023.2 XP_516023.2
cow (Bos taurus)	ORC2L¹	--	origin recognition complex, subunit 2-like (yeast)	91.13(n) 89.84(a)	511281 XM_588587.3 XP_588587.3
rat (Rattus norvegicus)	Orc2l¹	--	origin recognition complex, subunit 2-like (yeast)	83.8(n) 79.09(a)	301430 NM_001012003.1 NP_001012003.1
mouse (Mus musculus)	Orc2l^{1, 5}	1⁵	origin recognition complex, subunit 2-like (S. cerevisiae)^{1, 5}	84.55(n)¹ 78.99(a)¹	18393¹ NM_008765.2¹ NP_032791.1¹ AB190256⁵ AI447692⁵ (see all 21)

About this table Species with no ortholog for ORC2L

ENSEMBL Gene Tree for ORC2L

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/267 NCBI SNPs in ORC2L are shown (see all 267 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 56)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs874358^1,2	A,C,F,H,O	201537847(-)	`CAGGGG/CTTTCA`	1	--	ng3¹		9	MN EU EA WA NA NS	910
	rs3087357^1,2	C,F,H,O	201536610(-)	`CCTCCG/CGTGCT`	1	--	ut5¹ ese³		6	NA NS EU EA WA	772
	rs16836399^1,2	C,F,H	201538045(-)	`ACTCTA/GTATCT`	1	--	ng3¹		8	NA NS EU EA WA	716
	rs16836377^1,2	C,F,H	201537781(-)	`TTAGCT/GACTCC`	1	--	ng3¹		11	NS EU EA WA	1250
	rs2307361^1,2	C,F,H	201522533(-)	`AAAGAT/AGGCTA`	1	K/M	mis¹		6	NA NS EU EA WA	770
--	rs16836367^1,2	C,F	201537432(-)	`CTAGCC/TGTCCG`	1	--	ng3¹		7	NS	826
--	rs16835522^1,2	C,F	201483889(-)	`TGTTTG/TTTCCA`	1	--	ut3¹ ese³		7	NS	842
--	rs16836405^1,2	C,F	201538071(-)	`TTCCTA/GAACAG`	1	--	ng3¹		10	NA NS	746
--	rs16835624^1,2	H	201486348(-)	`GTGTCG/AGGAGG`	1	Q/R	mis¹		5	NS EU EA WA	572
--	rs16835518^1,2	F	201482938(-)	`GCCTGG/AGCAAC`	1	--	ng5¹		1	NS	168

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HapMap Linkage Disequilibrium images for ORC2L (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 601182

1 Novoseek disease relationship for ORC2L gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
cancer	0.00	2	11509178 (1)

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(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/56 PubMed articles for ORC2L gene (see all 56 ):

Mouse and human homologues of the yeast origin of replication recognition complex subunit ORC2 and chromosomal localization of the cognate human gene ORC2L. (PubMed id 8808289)^{1, 2, 3, 4} Takahara K.... Greenspan D.S. (1996)
The human homolog of Saccharomyces cerevisiae Mcm10 interacts with replication factors and dissociates from nuclease-resistant nuclear structures in G(2) phase. (PubMed id 11095689)^{1, 3, 4} Izumi M.... Hanaoka F. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Conserved initiator proteins in eukaryotes. (PubMed id 7502077)^{3, 4} Gavin K.A.... Stillman B.D. (1995)
Replication from oriP of Epstein-Barr virus requires human ORC and is inhibited by geminin. (PubMed id 11509178)^{1, 3} Dhar S.K....Dutta A. (2001)
Localization of proteins bound to a replication origin of human DNA along the cell cycle. (PubMed id 12912926)^{1, 3} Abdurashidova G....Falaschi A. (2003)
Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals. (PubMed id 10835370)^{1, 3} Natale D.A....DePamphilis M.L. (2000)
Human minichromosome maintenance proteins and human origin recognition complex 2 protein on chromatin. (PubMed id 9733749)^{1, 3} Ritzi M....Knippers R. (1998)
Proliferating human cells hypomorphic for origin recognition complex 2 and pre-replicative complex formation have a defect in p53 activation and Cdk2 kinase activation. (PubMed id 16407251)^{1, 3} Teer J.K....Dutta A. (2006)
Cell cycle-dependent proteolysis and phosphorylation of human Mcm10. (PubMed id 11602595)^{1, 3} Izumi M.... Hanaoka F. (2001)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 4999	HGNC: 8488	AceView: ORC2L	Ensembl:ENSG00000115942	euGenes: HUgn4999
ECgene: ORC2L	H-InvDB: ORC2L

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
NIEHS-SNPs	http://egp.gs.washington.edu/data/orc2l/

Licensable Technologies for ORC2L
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ORC2L:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ORC2L-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ORC2L		Antibodies for ORC2L
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ORC2L		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ORC2L)
	Antibodies (ORC2L)
	Chimera RNAi (ORC2L)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for ORC2L (ORC2)

	Recombinant Proteins (ORC2)
	Antibodies (ORC2)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for ORC2L

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for ORC2L

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ORC2L Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for ORC2L

Summaries
for ORC2L

Genomic Location
for ORC2L

Proteins
for ORC2L

Protein Domains/
Families
for ORC2L

Gene Function
for ORC2L

Pathways & Interactions
for ORC2L

Drugs & Compounds
for ORC2L

Transcripts
for ORC2L

Expression
for ORC2L

Orthologs
for ORC2L

Paralogs
for ORC2L

SNPs/Variants
for ORC2L

Disorders & Mutations
for ORC2L

Medical News
for ORC2L

Publications
for ORC2L

Search for ORC2L

Genome Databases showing ORC2L

Other Databases showing ORC2L

Specialized Databases showing ORC2L

Licensable Technologies
for ORC2L

Services
for ORC2L

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ORC2L Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor ORC2L

Summariesfor ORC2L

Genomic Locationfor ORC2L

Proteinsfor ORC2L

Protein Domains/Familiesfor ORC2L

Gene Functionfor ORC2L

Pathways & Interactionsfor ORC2L

Drugs & Compoundsfor ORC2L

Transcriptsfor ORC2L

Expression for ORC2L

Orthologsfor ORC2L

Paralogsfor ORC2L

SNPs/Variantsfor ORC2L

Disorders & Mutationsfor ORC2L

Medical Newsfor ORC2L

Publicationsfor ORC2L

Search for ORC2L

Genome Databases showing ORC2L

Other Databases showing ORC2L

Specialized Databases showing ORC2L

Licensable Technologiesfor ORC2L

Servicesfor ORC2L

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ORC2L

Summaries
for ORC2L

Genomic Location
for ORC2L

Proteins
for ORC2L

Protein Domains/
Families
for ORC2L

Gene Function
for ORC2L

Pathways & Interactions
for ORC2L

Drugs & Compounds
for ORC2L

Transcripts
for ORC2L

Expression
for ORC2L

Orthologs
for ORC2L

Paralogs
for ORC2L

SNPs/Variants
for ORC2L

Disorders & Mutations
for ORC2L

Medical News
for ORC2L

Publications
for ORC2L

Licensable Technologies
for ORC2L

Services
for ORC2L