Free for academic non-profit institutions. Other users need a Commercial license

Aliases for ORAOV1 Gene

Aliases for ORAOV1 Gene

  • Oral Cancer Overexpressed 1 2 3
  • TAOS1 3 4 6
  • Tumor-Amplified And Overexpressed Sequence 1 3 4
  • Oral Cancer Overexpressed Protein 1-A 2 3
  • Oral Cancer-Overexpressed Protein 1 3

External Ids for ORAOV1 Gene

Previous GeneCards Identifiers for ORAOV1 Gene

  • GC11M071975
  • GC11M071166
  • GC11M069727
  • GC11M069253
  • GC11M069189
  • GC11M069468
  • GC11M065772

Summaries for ORAOV1 Gene

GeneCards Summary for ORAOV1 Gene

ORAOV1 (Oral Cancer Overexpressed 1) is a Protein Coding gene. Diseases associated with ORAOV1 include oral cancer and gastric adenocarcinoma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ORAOV1 Gene

Genomics for ORAOV1 Gene

Regulatory Elements for ORAOV1 Gene

Genomic Location for ORAOV1 Gene

Start:
69,653,076 bp from pter
End:
69,675,416 bp from pter
Size:
22,341 bases
Orientation:
Minus strand

Genomic View for ORAOV1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ORAOV1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ORAOV1 Gene

Proteins for ORAOV1 Gene

  • Protein details for ORAOV1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WV07-ORAV1_HUMAN
    Recommended name:
    Oral cancer-overexpressed protein 1
    Protein Accession:
    Q8WV07
    Secondary Accessions:
    • B2R4R2
    • Q8NFK0

    Protein attributes for ORAOV1 Gene

    Size:
    137 amino acids
    Molecular mass:
    15354 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • Amplified and overexpressed in oral cancer cells

neXtProt entry for ORAOV1 Gene

Proteomics data for ORAOV1 Gene at MOPED

Post-translational modifications for ORAOV1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ORAOV1 Gene

Domains for ORAOV1 Gene

Protein Domains for ORAOV1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for ORAOV1 Gene

Graphical View of Domain Structure for InterPro Entry

Q8WV07

UniProtKB/Swiss-Prot:

ORAV1_HUMAN :
  • Q8WV07
Family:
  • Belongs to the ORAOV1 family.
genes like me logo Genes that share domains with ORAOV1: view

No data available for Gene Families for ORAOV1 Gene

Function for ORAOV1 Gene

Gene Ontology (GO) - Molecular Function for ORAOV1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with ORAOV1: view
genes like me logo Genes that share phenotypes with ORAOV1: view

miRNA for ORAOV1 Gene

miRTarBase miRNAs that target ORAOV1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ORAOV1 Gene

Localization for ORAOV1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ORAOV1 Gene COMPARTMENTS Subcellular localization image for ORAOV1 gene
Compartment Confidence
cytosol 3
extracellular 2
nucleus 1

Gene Ontology (GO) - Cellular Components for ORAOV1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with ORAOV1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for ORAOV1 Gene

Pathways for ORAOV1 Gene

SuperPathways for ORAOV1 Gene

No Data Available

Interacting Proteins for ORAOV1 Gene

Gene Ontology (GO) - Biological Process for ORAOV1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with ORAOV1: view

No data available for Pathways by source for ORAOV1 Gene

Transcripts for ORAOV1 Gene

Unigene Clusters for ORAOV1 Gene

Oral cancer overexpressed 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ORAOV1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f ^ 7 ^ 8
SP1: - - - - - - - - - - -
SP2: - - - - - -
SP3: - - -
SP4: - - - - - - -
SP5: - - - - -
SP6: - - - - - - - -
SP7: - - - - - -
SP8: - - - - - - -
SP9: - - - -
SP10: - - - - - - - - -
SP11: - -
SP12: - -
SP13:

Relevant External Links for ORAOV1 Gene

GeneLoc Exon Structure for
ORAOV1
ECgene alternative splicing isoforms for
ORAOV1

Expression for ORAOV1 Gene

mRNA expression in normal human tissues for ORAOV1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for ORAOV1 Gene

SOURCE GeneReport for Unigene cluster for ORAOV1 Gene Hs.667996

mRNA Expression by UniProt/SwissProt for ORAOV1 Gene

Q8WV07-ORAV1_HUMAN
Tissue specificity: Widely expressed. Highly expressed in placenta, kidney and skeletal muscle.
genes like me logo Genes that share expressions with ORAOV1: view

No data available for mRNA differential expression in normal tissues for ORAOV1 Gene

Orthologs for ORAOV1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ORAOV1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ORAOV1 35
  • 99.51 (n)
  • 100 (a)
ORAOV1 36
  • 53 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ORAOV1 35
  • 85.64 (n)
  • 89.78 (a)
ORAOV1 36
  • 80 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ORAOV1 35
  • 86.62 (n)
  • 91.24 (a)
ORAOV1 36
  • 48 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Oraov1 35
  • 77.13 (n)
  • 77.37 (a)
Oraov1 16
Oraov1 36
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ORAOV1 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ORAOV1 36
  • 69 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Oraov1 35
  • 76.31 (n)
  • 77.69 (a)
chicken
(Gallus gallus)
Aves ORAOV1 35
  • 69.38 (n)
  • 69.63 (a)
ORAOV1 36
  • 63 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ORAOV1 36
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia oraov1 35
  • 63.26 (n)
  • 52.55 (a)
zebrafish
(Danio rerio)
Actinopterygii oraov1 35
  • 64.44 (n)
  • 56.3 (a)
oraov1 36
  • 51 (a)
OneToOne
Species with no ortholog for ORAOV1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ORAOV1 Gene

ENSEMBL:
Gene Tree for ORAOV1 (if available)
TreeFam:
Gene Tree for ORAOV1 (if available)

Paralogs for ORAOV1 Gene

Pseudogenes.org Pseudogenes for ORAOV1 Gene

genes like me logo Genes that share paralogs with ORAOV1: view

No data available for Paralogs for ORAOV1 Gene

Variants for ORAOV1 Gene

Sequence variations from dbSNP and Humsavar for ORAOV1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1055825 -- 69,665,595(-) AACTG(G/T)AAAAA utr-variant-3-prime
rs1789164 -- 69,674,395(-) TAGTG(C/G)CAGTT intron-variant
rs1789165 -- 69,667,201(+) TGACT(A/G)ACCCT utr-variant-3-prime, intron-variant
rs1789166 -- 69,667,323(+) TGTGG(A/C)GAGGC utr-variant-3-prime, intron-variant
rs1789167 -- 69,671,476(+) GCCAC(A/G)TGGTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ORAOV1 Gene

Variant ID Type Subtype PubMed ID
dgv16n68 CNV Loss 17160897
nsv825973 CNV Gain 20364138
nsv825974 CNV Gain 20364138

Relevant External Links for ORAOV1 Gene

HapMap Linkage Disequilibrium report
ORAOV1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ORAOV1 Gene

Disorders for ORAOV1 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (3) Diseases for ORAOV1 Gene including...

Search for ORAOV1 Gene in MalaCards »
genes like me logo Genes that share disorders with ORAOV1: view

No data available for UniProtKB/Swiss-Prot for ORAOV1 Gene

Publications for ORAOV1 Gene

  1. High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells. (PMID: 12172009) Huang X. … Godfrey T.E. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 4 23
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Amplifications of TAOS1 and EMS1 genes in oral carcinogenesis: association with clinicopathological features. (PMID: 17005439) Xia J. … Zeng X. (Oral Oncol. 2007) 3
  4. Oral cancer overexpressed 1 (ORAOV1): a regulator for the cell growth and tumor angiogenesis in oral squamous cell carcinoma. (PMID: 18688849) Jiang L. … Chen Q. (Int. J. Cancer 2008) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for ORAOV1 Gene

  • antibodies-online proteins for ORAOV1
  • antibodies-online antibodies for ORAOV1
  • antibodies-online kits for ORAOV1

Sources for ORAOV1 Gene

Back to Top

Content