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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ORAOV1 Gene

protein-coding GIFtS: 49
GCID: GC11M069468

oral cancer overexpressed 1

Explore 6 diseases affiliated with
ORAOV1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Oral Cancer Overexpressed 1¹ ²
TAOS1¹ ² ³ ⁵
Tumor-Amplified And Overexpressed Sequence 1² ³
Oral Cancer Overexpressed Protein 1-A²
Oral Cancer-Overexpressed Protein 1²

External Ids:	HGNC: 17589¹	Entrez Gene: 220064²	Ensembl: ENSG00000149716⁷	OMIM: 607224⁵	UniProtKB: Q8WV07³

Export aliases for ORAOV1 gene to outside databases

Previous GC identifers: GC11M071975 GC11M071166 GC11M069727 GC11M069253 GC11M069189 GC11M065772

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_167190.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ORAOV1 gene promoter:
Sp1 Tal-1 Olf-1 IRF-1 GATA-1 HNF-1A C/EBPalpha E47 GATA-2 HNF-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ORAOV1 promoter sequence

Search SABiosciences Chromatin IP Primers for ORAOV1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ORAOV1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13.3 Ensembl cytogenetic band: 11q13.3 HGNC cytogenetic band: 11q13.2

ORAOV1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ORAOV1 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M069468: view genomic region (about GC identifiers)

Start:	69,467,844 bp from pter	End:	69,490,184 bp from pter
Size:	22,341 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ORAV1_HUMAN, Q8WV07 (See protein sequence)

Recommended Name: Oral cancer-overexpressed protein 1

Size: 137 amino acids; 15354 Da

Miscellaneous: Amplified and overexpressed in oral cancer cells

Secondary accessions: B2R4R2 Q8NFK0

Explore the universe of human proteins at neXtProt for ORAOV1: NX_Q8WV07

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8WV07

ORAOV1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_703152.1

ENSEMBL proteins:

ENSP00000446428 ENSP00000279147 ENSP00000441984 ENSP00000455359 ENSP00000446129

ENSP00000443669 ENSP00000443936 ENSP00000444112 ENSP00000409643 ENSP00000437367

Human Recombinant Protein Products for ORAOV1:

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	Novus Biologicals ORAOV1 Proteins Novus Biologicals ORAOV1 Lysate
	Browse Sino Biological Recombinant Proteins
	ProSpec Recombinant Protein for ORAOV1
	Uscn Proteins for ORAOV1

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005575	cellular_component	ND	--

ORAOV1 for ontologies About GeneDecksing

ORAOV1 Antibody Products:

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	Search ThermoFisher Antibodies for ORAOV1

Assay Products for ORAOV1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ORAOV1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ORAOV1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ORAOV1 for domains About GeneDecksing

1 InterPro domain/family:

IPR019191 Essential_protein_Yae1_N

Graphical View of Domain Structure for InterPro Entry Q8WV07

ProtoNet protein and cluster: Q8WV07

UniProtKB/Swiss-Prot: ORAV1_HUMAN, Q8WV07

Similarity: Belongs to the ORAOV1 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

ORAOV1 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for ORAOV1:

Decreased viability of wild-ty

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ORAOV1

miRNA Products:		OriGene 3'-UTR Clone: ORAOV1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ORAOV1
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate ORAOV1:
		hsa-miR-1206 hsa-miR-26b*
		SwitchGear 3'UTR luciferase reporter plasmid: ORAOV1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ORAOV1 (see all 7) OriGene shRNA RFP: ORAOV1 OriGene siRNA: ORAOV1
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		Sirion Biotech Custom design and validation of potent shRNA sequences against ORAOV1

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for ORAOV1
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Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ORAOV1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ORAOV1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ORAOV1
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ORAOV1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ORAOV1

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

2 Interacting proteins for ORAOV1 (Q8WV07³ ENSP00000279147⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GABARAPL2	P60520³	I2D: score=1
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

ORAOV1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ORAOV1
Search CenterWatch for drugs/clinical trials and news about ORAOV1 / ORAV1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ORAOV1 gene:

NM_153451.2

Unigene Cluster for ORAOV1:

Oral cancer overexpressed 1

Hs.667996 [show with all ESTs]

Unigene Representative Sequence: AK126490

18/19 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):

ENST00000542515(uc010rqh.1) ENST00000569105 ENST00000538554(uc010rqi.1)

ENST00000279147(uc001opc.3 uc009ysm.3 uc001opd.3) ENST00000544096

ENST00000536870 ENST00000537272 ENST00000535657 ENST00000542470 ENST00000535542

ENST00000543863 ENST00000543562 ENST00000539414 ENST00000441922 ENST00000537324

ENST00000541291 ENST00000542341(uc001ope.1) ENST00000355486

miRNA Products:		OriGene 3'-UTR Clone: ORAOV1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ORAOV1
		2 QIAGEN miScript miRNA Assays for microRNAs that regulate ORAOV1:
		hsa-miR-1206 hsa-miR-26b*
		SwitchGear 3'UTR luciferase reporter plasmid: ORAOV1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ORAOV1 (see all 7) OriGene shRNA RFP: ORAOV1 OriGene siRNA: ORAOV1
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		Sirion Biotech Custom design and validation of potent shRNA sequences against ORAOV1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ORAOV1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ORAOV1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: ORAOV1 (NM_153451)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ORAOV1
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ORAOV1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ORAOV1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ORAOV1

Additional cDNA sequence:

AF503940.1 AK026600.1 AK125280.1 AK126490.1 AK294004.1 AK311918.1 BC006448.2 BC019024.1

BC065542.1 EF639695.1 JX460858.1

17 DOTS entries:

DT.97869862 DT.437026 DT.97812341 DT.120734297 DT.91923745 DT.100771800 DT.97802642 DT.91738695

DT.100735643 DT.100755144 DT.70105440 DT.91638611 DT.100755143 DT.91752669 DT.95287813 DT.120734273

DT.92046346

24/194 AceView cDNA sequences (see all 194):

BM770175 AI571105 BM770125 BP871305 BG153386 BQ050679 BM770735 BM126256

BM756466 CF593377 BX404647 NM_001004327 BM770986 BC065542 BU181761 AK126490

BM756560 BX440862 BM770139 BM770094 BM770687 NM_153451 CB242407 BM771397

GeneLoc Exon Structure

5/13 Alternative Splicing Database (ASD) splice patterns (SP) for ORAOV1 (see all 13) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	·	1g	^	2a	·	2b	^	3a	·	3b	·	3c	^	4a	·	4b	·	4c	^	5a	·	5b	^	6a	·	6b	·	6c	·	6d	·	6e	·	6f	^	7	^	8
SP1:															-		-						-		-				-				-				-		-		-		-		-
SP2:															-		-						-		-				-				-
SP3:																							-		-				-
SP4:															-		-						-		-		-		-				-
SP5:															-		-						-		-				-

ECgene alternative splicing isoforms for ORAOV1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ORAOV1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTGGTGCTGG

About this image

ORAOV1 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Neural Tube

Metencephalon

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ORAOV1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ORAOV1

SOURCE GeneReport for Unigene cluster: Hs.667996

UniProtKB/Swiss-Prot: ORAV1_HUMAN, Q8WV07

Tissue specificity: Widely expressed. Highly expressed in placenta, kidney and skeletal muscle

SABiosciences Custom PCR Arrays for ORAOV1

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		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ORAOV1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ORAOV1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for ORAOV1 gene from 5/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Oraov1^{1 , 5}	oral cancer overexpressed 1^{1, 5}	77.13(n)¹ 77.37(a)¹		7 (88.92 cM)⁵ 72284¹ NM_028184.3¹ NP_082460.2¹ 144915100⁵
chicken (Gallus gallus)	Aves	ORAOV1¹	oral cancer overexpressed 1	69.38(n) 69.63(a)		423142 NM_001031186.1 NP_001026357.1
lizard (Anolis carolinensis)	Reptilia	ORAOV1⁶	--	53(a)	1 ↔ 1	1(55265795-55270953)
zebrafish (Danio rerio)	Actinopterygii	oraov1¹	oral cancer overexpressed 1	65.38(n) 56.92(a)		563810 NM_001083552.1 NP_001077021.1
rice (Oryza sativa)	Liliopsida	--	oral cancer overexpressed protein 1, putative, exp...	26(a)	1 ↔ 1	7(20748673-20750840)

ENSEMBL Gene Tree for ORAOV1 (if available)
TreeFam Gene Tree for ORAOV1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ORAOV1 gene

ORAOV1 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for ORAOV1
PGOHUM00000245789

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs149504872^1,2		--	69479850(+)	`GCAGGC/TGTAGG`	1	--	int¹		0	--	--	--	--
rs76745514^1,2		--	69479984(+)	`AGGGAG/CAGAGA`	1	--	int¹		2		CSA WA	120
rs144183156^1,2		--	69480157(+)	`ACTCTC/TGCAGT`	1	--	int¹		0	--	--	--	--
rs11263527^1,2	C,F,A,H	--	69480191(+)	`GAGACA/GAGCTG`	1	--	int¹		18		NS EA NA WA CSA	2222
rs186747324^1,2		--	69480194(+)	`ACAAGA/CTGGCA`	1	--	int¹		0	--	--	--	--
rs73522751^1,2	C,F	--	69480287(+)	`TAAATG/AATGCC`	1	--	int¹		4		WA CSA	124
rs76914932^1,2	F	--	69480293(+)	`ATGCCG/ATGTTA`	1	--	int¹		1		WA	118
rs111567816^1,2		--	69480321(+)	`TAAATG/CGTCCC`	1	--	int¹		1		CSA	2
rs1055825^1,2	C,F	--	69480363(-)	`NNNNGT/GAAAAA`	1	--	ut3¹		7		WA NA CSA	246
rs76071191^1,2		--	69480379(+)	`AATAAT/CACATT`	1	--	ut3¹		2		CSA WA	119

HapMap Linkage Disequilibrium report for ORAOV1 (69467844 - 69490184 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for ORAOV1
1 CNV: 4755

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ORAOV1

DNA2.0 Custom Variant and Variant Library Synthesis for ORAOV1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ORAOV1 for disorders           About GeneDecksing

OMIM gene information: 607224    OMIM disorders: --

6 diseases for ORAOV1:    About MalaCards

oral cancer oral squamous cell carcinoma squamous cell carcinoma cervical cancer

cervicitis carcinoma

Export disorders for ORAOV1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ORAOV1 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with ORAOV1)

Utopia: connect your pdf to the dynamic
world of online information

High-resolution mapping of the 11q13 amplicon and identification of a gene, TAOS1, that is amplified and overexpressed in oral cancer cells. (PubMed id 12172009)^{1, 2, 3, 9} Huang X.... Godfrey T.E. (2002)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
ORAOV1 is a probable target within the 11q13.3 amplico n in lymph node metastases from gastric adenocarcinoma. (PubMed id 21993861)¹ Kang J.U. and Koo S.H. (2012)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
ORAOV1 is amplified in oral squamous cell carcinoma. (PubMed id 21623924)¹ Xavier F.C....Nunes F.D. (2012)
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)² Rigbolt K.T....Blagoev B. (2011)
Oral cancer overexpressed 1 (ORAOV1) regulates cell c ycle and apoptosis in cervical cancer HeLa cells. (PubMed id 20105337)¹ Jiang L....Chen Q. (2010)
Genome-wide association study identifies five new bre ast cancer susceptibility loci. (PubMed id 20453838)¹ Turnbull C....Easton D.F. (2010)
Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)¹ Bennett E.J....Harper J.W. (2010)
ORAOV1-A correlates with poor differentiation in oral cancer. (PubMed id 19493886)¹ Jiang L....Chen Q.M. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 220064	HGNC: 17589	AceView: ORAOV1andFLJ42258	Ensembl:ENSG00000149716	euGenes: HUgn220064
ECgene: ORAOV1	H-InvDB: ORAOV1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ORAOV1	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ORAOV1	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ORAOV1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for ORAOV1 gene:
Search GeneIP for patents involving ORAOV1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
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	Regulatory tfbs in ORAOV1 promoter
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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Recombinant Protein for ORAOV1

ORAOV1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for ORAOV1

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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ORAOV1

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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ORAOV1

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ORAOV1

Sirion Biotech Customized:

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ORAOV1 Gene

oral cancer overexpressed 1

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ORAOV1 Gene

oral cancer overexpressed 1

Aliasesfor ORAOV1 gene

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External Searches for ORAOV1 gene

Genome Databases showing ORAOV1 gene

Other Databases showing ORAOV1 gene

Specialized Databases showing ORAOV1 gene

Intellectual Propertyfor ORAOV1 gene

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Summaries
for ORAOV1 gene

Genomic Views
for ORAOV1 gene

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for ORAOV1 gene

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Families
for ORAOV1 gene

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for ORAOV1 gene

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for ORAOV1 gene

Drugs & Compounds
for ORAOV1 gene

Transcripts
for ORAOV1 gene

Expression
for ORAOV1 gene

Orthologs
for ORAOV1 gene

Paralogs
for ORAOV1 gene

Genomic Variants
for ORAOV1 gene

Disorders / Diseases
for ORAOV1 gene

Publications
for ORAOV1 gene

Intellectual Property
for ORAOV1 gene

Products
for ORAOV1 gene