ORAI2 Gene
protein-coding GIFtS: 51
GCID: GC07P102074
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|
ORAI calcium release-activated calcium modulator 2(Previous names: chromosome 7 open reading frame 19, transmembrane protein...)
(Previous symbols: C7orf19, TMEM142B)
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Aliases
for ORAI2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ORAI Calcium Release-Activated Calcium Modulator 21 2 | | MEM142B2 5 | | C7orf191 2 3 5 | | FLJ124741 | | Transmembrane Protein 142B1 2 3 | | FLJ147331 | | CBCIP21 2 3 | | Chromosome 7 Open Reading Frame 191 | | TMEM142B1 2 3 | | CAP-Binding Protein Complex Interacting Protein 22 | | H_NH0514P08.81 2 | | Protein Orai-22 | | CAP-Binding Protein Complex-Interacting Protein 22 3 | | Putative Protein ORAI2-22 |
Export aliases for ORAI2 gene to outside databasesPrevious GC identifers: GC07P101862 GC07P096656 |
Summaries
for ORAI2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: ORAI2_HUMAN, Q96SN7Function: Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase inCa(2+)-selective current by synergy with the Ca(2+) sensor, STIM1
 summary
for ORAI2: STIM-Orai channels have recently been identified as the underlying molecular mechanism of store-operated
calcium entry (SOCE). SOCE allows rapid Ca2+ efflux from the endoplasmic reticulum (ER), following the
emptying of intracellular Ca2+ stores. STIM (sensors stromal interaction molecule) proteins, STIM1 and
STIM2, serve as ER Ca2+ sensors. They contain N'-terminal Ca2+-sensing EF-hand domains and are localized to
the tubular ER. Following Ca2+ store depletion, STIMs rapidly cluster and relocalize to the plasma
membrane-adjacent ER regions, where they oligomerize and form 'puncta'. Orai proteins, Orai1, Orai2 and
Orai3, are STIM binding partners that form the pore of the channel. Orai proteins are uniformly distributed
in the plasma membrane and exist as dimers in the resting state. STIM activation induces tetramerization of
Orai proteins and subsequent STIM-Orai colocalization, which forms the active store-operated calcium
channel.
Gene Wiki entry for ORAI2
|
Genomic Views
for ORAI2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ORAI2 gene promoter:
COUP-TF1 GR Bach2 HNF-4alpha1 AREB6 RORalpha1 PPAR-gamma1 COUP-TF GR-alpha PPAR-gamma2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ORAI2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ORAI2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22.1ORAI2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P102074: view genomic region
(about GC identifiers)
Start:
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102,073,553 bp from pter |
End:
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102,097,268 bp from pter |
Size:
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23,716 bases |
Orientation:
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plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 101,434,297-101,457,569 |
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Proteins
for ORAI2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ORAI2_HUMAN, Q96SN7 (See
protein sequence)Recommended Name: Protein orai-2 Size: 254 amino acids; 28570 Da
Subunit: Interacts with EFCAB4B/CRACR2A
Subcellular location: Membrane; Multi-pass membrane protein (By similarity)
Sequence caution: Sequence=AAG23755.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=AAP22352.1;Type=Erroneous gene model prediction; Sequence=CAG33568.1; Type=Erroneous translation; Note=Wrong choice of CDS;
Secondary accessions: Q6IA68 Q8WY94 Q9H9Y3Explore the universe of human proteins at neXtProt for ORAI2: NX_Q96SN7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96SN7
ORAI2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001119812.1 NP_001258747.1 NP_001258748.1 NP_116220.1
ENSEMBL proteins: ENSP00000419416 ENSP00000420178 ENSP00000418140 ENSP00000417407 ENSP00000385489 ENSP00000418464 ENSP00000417928 ENSP00000348752
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
ORAI2 for ontologies About GeneDecksing
ORAI2 Antibody Products:
Assay Products for ORAI2: |
Protein
Domains /
Families
for ORAI2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ORAI2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q96SN7ProtoNet protein and cluster: Q96SN7 1 Blocks protein family: IPB012446 Protein of unknown function DUF1650
UniProtKB/Swiss-Prot: ORAI2_HUMAN, Q96SN7Similarity: Belongs to the Orai family |
Function
for ORAI2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ORAI2_HUMAN, Q96SN7Function: Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase inCa(2+)-selective current by synergy with the Ca(2+) sensor, STIM1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ORAI2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ORAI2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ORAI2 (NM_032831) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ORAI2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ORAI2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ORAI2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
ORAI2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ORAI2:
|
Pathways & Interactions
for ORAI2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ORAI2
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
5/7 Interacting proteins for ORAI2 (Q96SN73 ENSP000003487524) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
|
Drugs & Compounds
for ORAI2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for ORAI2 available from Tocris Bioscience About this table
Search CenterWatch for drugs/clinical trials and news about ORAI2
|
Transcripts
for ORAI2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ORAI2 gene (4 alternative transcripts): NM_001126340.2 NM_001271818.1 NM_001271819.1 NM_032831.3 Unigene Clusters for ORAI2: ORAI calcium release-activated calcium modulator 2 Hs.363308 [show with all ESTs], Hs.736659 [show with all ESTs]Unigene Representative Sequences: NM_001271819, NM_0012718189 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000482237 ENST00000495936 ENST00000488996 ENST00000478730 ENST00000468241
ENST00000403646 ENST00000498661 ENST00000473939 ENST00000356387(uc010lhz.1 uc003uzj.2 uc003uzk.2 uc011kks.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ORAI2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ORAI2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ORAI2 (NM_032831) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ORAI2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ORAI2 |
Additional cDNA sequence: AK027639.1 AK056497.1 BC069270.1 23 DOTS entries: DT.100735284 DT.101969520 DT.100888922 DT.121040063 DT.100740577 DT.109323 DT.100888927 DT.102840191 DT.121040282 DT.436608 DT.121040362 DT.121040398 DT.95163030 DT.97869174 DT.121040140 DT.121040227 DT.100740575 DT.121040162 DT.95276867 DT.100740574 DT.121040545 DT.422481 DT.91863151 24/170 AceView cDNA sequences (see all 170): AA375649 AW592376 BE207007 AI554664 BM480375 BC016797 BX475379 AA766538 CA951030 AI758348 AI675155 Z41515 AI569823 AW044192 BQ672263 AI038477 AW576484 AI760535 AI494558 AI066649 BC009183 BE674677 BG756954 BQ054350
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for ORAI2 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ORAI2
|
Expression
for ORAI2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ORAI2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See ORAI2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ORAI2
SOURCE GeneReport for Unigene clusters: Hs.363308 Hs.736659
SABiosciences Custom PCR Arrays for ORAI2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ORAI2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ORAI2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ORAI2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ORAI2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ORAI2 |
Orthologs
for ORAI2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ORAI2 gene from 4/19 species (see all 19) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ORAI21 |
ORAI calcium release-activated calcium modulator 2 |
82.68(n)
89.76(a) |
|
417509 NM_001030710.1 NP_001025881.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.140762 |
Transcribed sequence with moderate similarity to protein more |
85.12(n) |
|
BI844783.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
olf186-F6 |
olf186-F |
23(a) |
1 → many |
2R(13730950-13748075) |
worm
(Caenorhabditis elegans) |
Secernentea |
orai-16 |
Protein orai |
28(a) |
1 → many |
III(647123-654460) |
ENSEMBL Gene Tree for ORAI2 (if available)
TreeFam Gene Tree for ORAI2 (if available) |
Paralogs
for ORAI2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ORAI2 gene
- ORAI32 ORAI12
2 SIMAP similar genes for ORAI2 using alignment to 5 protein entries: ORAI2_HUMAN (see all proteins):ORAI1 ORAI3
ORAI2 for paralogs About GeneDecksing
|
Genomic Variants
for ORAI2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ORAI2 (102073553 - 102097268 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ORAI2
3 CNVs: 36585 4553 31385 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ORAI2 |
|
Disorders
/ Diseases
for ORAI2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ORAI2 for disorders About GeneDecksing
OMIM gene information: 610929
OMIM disorders: --
3  diseases for ORAI2: About MalaCardsestrogen-receptor negative breast cancer breast cancer retinitis
Export disorders for ORAI2 gene to outside databases
|
Publications
for ORAI2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ORAI2 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with ORAI2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function. (PubMed id 16582901)1, 2, 3 Feske S.... Rao A. (2006)
- Calcium inhibition and calcium potentiation of orai1, orai2, and orai3 calcium release-activated calcium channels. (PubMed id 17452328)1, 2 Dehaven W.I.... Putney J.W. Jr. (2007)
- Large store-operated calcium selective currents due to co-expression of Orai1 or Orai2 with the intracellular calcium sensor, Stim1. (PubMed id 16807233)1, 2 Mercer J.C.... Putney J.W. Jr. (2006)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Capacitative and non-capacitative signaling complexes in human platelets. (PubMed id 22640869)1 Berna-Erro A....Rosado J.A. (2012)
- Expression of Orai genes and I(CRAC) activation in th e human retinal pigment epithelium. (PubMed id 20607548)1 Cordeiro S. and Strauss O. (2011)
- A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells. (PubMed id 20418871)2 Srikanth S....Gwack Y. (2010)
|
External Searches for ORAI2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ORAI2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ORAI2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ORAI2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ORAI2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ORAI2 gene:
Search GeneIP for patents involving ORAI2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ORAI2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for ORAI2 | | OriGene shRNA RFP for ORAI2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ORAI2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ORAI2 | | | OriGene Protein Over-expression Lysate for ORAI2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ORAI2 | | OriGene 3'-UTR Clone for ORAI2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ORAI2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ORAI2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ORAI2 | | OriGene Custom Protein Services for ORAI2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ORAI2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ORAI2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ORAI2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ORAI2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ORAI2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ORAI2 |
| |
 |  |  |  | |
| | | | Tocris compounds for ORAI2 |
| |  |  |  |  | | | | |
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 | | | ORAI2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ORAI2 |
|  |  |  | | | | ThermoFisher Antibodies for ORAI2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ORAI2 |
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