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Aliases for OR9Q2 Gene

Aliases for OR9Q2 Gene

  • Olfactory Receptor, Family 9, Subfamily Q, Member 2 2 3
  • OR9Q2P 3 4
  • Olfactory Receptor, Family 9, Subfamily Q, Member 2 Pseudogene 3

External Ids for OR9Q2 Gene

Previous HGNC Symbols for OR9Q2 Gene

  • OR9Q2P

Previous GeneCards Identifiers for OR9Q2 Gene

  • GC11P057735
  • GC11P057714
  • GC11P057957

Summaries for OR9Q2 Gene

Entrez Gene Summary for OR9Q2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9Q2 Gene

OR9Q2 (Olfactory Receptor, Family 9, Subfamily Q, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR8H2.

UniProtKB/Swiss-Prot for OR9Q2 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9Q2 Gene

Genomics for OR9Q2 Gene

Regulatory Elements for OR9Q2 Gene

Genomic Location for OR9Q2 Gene

Chromosome:
11
Start:
58,190,434 bp from pter
End:
58,191,518 bp from pter
Size:
1,085 bases
Orientation:
Plus strand

Genomic View for OR9Q2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR9Q2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9Q2 Gene

Proteins for OR9Q2 Gene

  • Protein details for OR9Q2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGE9-OR9Q2_HUMAN
    Recommended name:
    Olfactory receptor 9Q2
    Protein Accession:
    Q8NGE9

    Protein attributes for OR9Q2 Gene

    Size:
    314 amino acids
    Molecular mass:
    35363 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR9Q2 Gene

Proteomics data for OR9Q2 Gene at MOPED

Post-translational modifications for OR9Q2 Gene

No Post-translational modifications

Other Protein References for OR9Q2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9Q2 Gene

Domains & Families for OR9Q2 Gene

Gene Families for OR9Q2 Gene

Protein Domains for OR9Q2 Gene

Suggested Antigen Peptide Sequences for OR9Q2 Gene

Graphical View of Domain Structure for InterPro Entry

Q8NGE9

UniProtKB/Swiss-Prot:

OR9Q2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9Q2: view

Function for OR9Q2 Gene

Molecular function for OR9Q2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR9Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR9Q2: view

Phenotypes for OR9Q2 Gene

GenomeRNAi human phenotypes for OR9Q2:
genes like me logo Genes that share phenotypes with OR9Q2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR9Q2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR9Q2 Gene

Localization for OR9Q2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9Q2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR9Q2 Gene COMPARTMENTS Subcellular localization image for OR9Q2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR9Q2: view

Pathways & Interactions for OR9Q2 Gene

genes like me logo Genes that share pathways with OR9Q2: view

Pathways by source for OR9Q2 Gene

Interacting Proteins for OR9Q2 Gene

Gene Ontology (GO) - Biological Process for OR9Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9Q2: view

No data available for SIGNOR curated interactions for OR9Q2 Gene

Drugs & Compounds for OR9Q2 Gene

No Compound Related Data Available

Transcripts for OR9Q2 Gene

mRNA/cDNA for OR9Q2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR9Q2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR9Q2 Gene

No ASD Table

Relevant External Links for OR9Q2 Gene

GeneLoc Exon Structure for
OR9Q2
ECgene alternative splicing isoforms for
OR9Q2

Expression for OR9Q2 Gene

mRNA expression in normal human tissues for OR9Q2 Gene

mRNA differential expression in normal tissues according to GTEx for OR9Q2 Gene

This gene is overexpressed in Testis (x45.1) and Fallopian Tube (x7.8).

SOURCE GeneReport for Unigene cluster for OR9Q2 Gene Hs.553643

genes like me logo Genes that share expression patterns with OR9Q2: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR9Q2 Gene

Orthologs for OR9Q2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR9Q2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia OR9Q2 35
  • 79.45 (n)
  • 77.64 (a)
OR9Q2 36
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1497 35
  • 82.48 (n)
  • 85.67 (a)
Olfr1497 16
Olfr1497 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia LOC466596 35
  • 99.26 (n)
  • 98.09 (a)
OR9Q2 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr377 35
  • 81.62 (n)
  • 83.97 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 58 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 60 (a)
ManyToMany
Species with no ortholog for OR9Q2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR9Q2 Gene

ENSEMBL:
Gene Tree for OR9Q2 (if available)
TreeFam:
Gene Tree for OR9Q2 (if available)

Paralogs for OR9Q2 Gene

(456) SIMAP similar genes for OR9Q2 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR9Q2 Gene

genes like me logo Genes that share paralogs with OR9Q2: view

Variants for OR9Q2 Gene

Sequence variations from dbSNP and Humsavar for OR9Q2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs1376485 -- 58,189,415(-) TCTTT(A/T)GTTTA upstream-variant-2KB
rs1376486 -- 58,189,360(-) TTCTA(A/G)TTCAC upstream-variant-2KB
rs1451317 -- 58,191,500(-) AGAAG(G/T)TGCTA utr-variant-3-prime
rs2867404 -- 58,189,550(-) ACCTG(A/T)TGTAC upstream-variant-2KB
rs3911232 -- 58,188,437(+) GTGGG(A/G)CACTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR9Q2 Gene

Variant ID Type Subtype PubMed ID
nsv897589 CNV Gain 21882294
nsv832165 CNV Gain 17160897
nsv832166 CNV Gain+Loss 17160897

Variation tolerance for OR9Q2 Gene

Residual Variation Intolerance Score: 45.78% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.22; 88.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR9Q2 Gene

HapMap Linkage Disequilibrium report
OR9Q2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR9Q2 Gene

Disorders for OR9Q2 Gene

Relevant External Links for OR9Q2

Genetic Association Database (GAD)
OR9Q2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR9Q2
genes like me logo Genes that share disorders with OR9Q2: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR9Q2 Gene

Publications for OR9Q2 Gene

  1. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. (PMID: 17903306) Newton-Cheh C. … Larson M.G. (BMC Med. Genet. 2007) 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for OR9Q2 Gene

Sources for OR9Q2 Gene

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