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Aliases for OR9Q2 Gene

Aliases for OR9Q2 Gene

  • Olfactory Receptor Family 9 Subfamily Q Member 2 2 3 5
  • OR9Q2P 3 4
  • Olfactory Receptor, Family 9, Subfamily Q, Member 2 Pseudogene 3
  • Olfactory Receptor, Family 9, Subfamily Q, Member 2 2
  • Olfactory Receptor 9Q2 3

External Ids for OR9Q2 Gene

Previous HGNC Symbols for OR9Q2 Gene

  • OR9Q2P

Previous GeneCards Identifiers for OR9Q2 Gene

  • GC11P057735
  • GC11P057714
  • GC11P057957

Summaries for OR9Q2 Gene

Entrez Gene Summary for OR9Q2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9Q2 Gene

OR9Q2 (Olfactory Receptor Family 9 Subfamily Q Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR9Q1.

UniProtKB/Swiss-Prot for OR9Q2 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9Q2 Gene

Genomics for OR9Q2 Gene

Regulatory Elements for OR9Q2 Gene

Enhancers for OR9Q2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F058164 0.8 ENCODE 16.4 -25.1 -25116 2.0 ELF3 ATF1 MLX RAD21 RARA GATA4 CREM MIXL1 THAP11 HMG20B OR9Q2 OR1S2 OR10W1 RNU6-899P OR9Q1 MED19 TIMM10 OR5BL1P OR9I2P
GH11F057973 0.8 ENCODE 16.2 -216.3 -216319 0.5 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 TNKS1BP1 SSRP1 CTNND1 OR5AZ1P OR9Q2 RPS4XP13 OR5B1P OR5B15P OR5B21 BTBD18
GH11F057496 1.2 Ensembl ENCODE 16.2 -690.5 -690506 6.7 PKNOX1 ARID4B DMAP1 ZNF48 YY1 ZNF121 GLIS2 KLF7 FOS SP3 TIMM10 RPS4XP13 OR5AZ1P OR9Q2 OR5B1P OR5B15P BTBD18 RTN4RL2 RN7SKP259 MIR130A
GH11F057740 0.5 ENCODE 16.2 -448.5 -448545 2.7 HDGF PKNOX1 ARNT MLX CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 TNKS1BP1 SSRP1 CTNND1 RPS4XP13 OR5AZ1P OR9Q2 OR5B15P OR5B1P OR5B21 MED19
GH11F058133 0.6 ENCODE 10.6 -56.6 -56611 0.2 HDAC1 PKNOX1 TBL1XR1 RAD21 GATA2 SCRT2 ZBTB11 NCOA1 MBD2 KLF16 OR9Q2 OR9I1 OR9I2P
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR9Q2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR9Q2 Gene

Chromosome:
11
Start:
58,190,434 bp from pter
End:
58,191,518 bp from pter
Size:
1,085 bases
Orientation:
Plus strand

Genomic View for OR9Q2 Gene

Genes around OR9Q2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR9Q2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR9Q2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9Q2 Gene

Proteins for OR9Q2 Gene

  • Protein details for OR9Q2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGE9-OR9Q2_HUMAN
    Recommended name:
    Olfactory receptor 9Q2
    Protein Accession:
    Q8NGE9

    Protein attributes for OR9Q2 Gene

    Size:
    314 amino acids
    Molecular mass:
    35363 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR9Q2 Gene

Post-translational modifications for OR9Q2 Gene

No Post-translational modifications

Other Protein References for OR9Q2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9Q2 Gene

Domains & Families for OR9Q2 Gene

Gene Families for OR9Q2 Gene

Protein Domains for OR9Q2 Gene

Suggested Antigen Peptide Sequences for OR9Q2 Gene

Graphical View of Domain Structure for InterPro Entry

Q8NGE9

UniProtKB/Swiss-Prot:

OR9Q2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9Q2: view

Function for OR9Q2 Gene

Molecular function for OR9Q2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR9Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR9Q2: view

Phenotypes for OR9Q2 Gene

GenomeRNAi human phenotypes for OR9Q2:
genes like me logo Genes that share phenotypes with OR9Q2: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR9Q2 Gene

Localization for OR9Q2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9Q2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR9Q2 Gene COMPARTMENTS Subcellular localization image for OR9Q2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR9Q2: view

Pathways & Interactions for OR9Q2 Gene

genes like me logo Genes that share pathways with OR9Q2: view

Pathways by source for OR9Q2 Gene

Interacting Proteins for OR9Q2 Gene

Gene Ontology (GO) - Biological Process for OR9Q2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9Q2: view

No data available for SIGNOR curated interactions for OR9Q2 Gene

Transcripts for OR9Q2 Gene

mRNA/cDNA for OR9Q2 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR9Q2 Gene

No ASD Table

Relevant External Links for OR9Q2 Gene

GeneLoc Exon Structure for
OR9Q2
ECgene alternative splicing isoforms for
OR9Q2

Expression for OR9Q2 Gene

mRNA expression in normal human tissues for OR9Q2 Gene

mRNA differential expression in normal tissues according to GTEx for OR9Q2 Gene

This gene is overexpressed in Testis (x45.1) and Fallopian Tube (x7.8).

NURSA nuclear receptor signaling pathways regulating expression of OR9Q2 Gene:

OR9Q2

SOURCE GeneReport for Unigene cluster for OR9Q2 Gene:

Hs.553643
genes like me logo Genes that share expression patterns with OR9Q2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR9Q2 Gene

Orthologs for OR9Q2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR9Q2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466596 34
  • 99.26 (n)
OR9Q2 35
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Or9q2 55 Olfr1497 34 16 35
  • 82.48 (n)
rat
(Rattus norvegicus)
Mammalia Olr377 34
  • 81.62 (n)
cow
(Bos Taurus)
Mammalia OR9Q2 34 35
  • 79.45 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 60 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 58 (a)
ManyToMany
Species where no ortholog for OR9Q2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR9Q2 Gene

ENSEMBL:
Gene Tree for OR9Q2 (if available)
TreeFam:
Gene Tree for OR9Q2 (if available)

Paralogs for OR9Q2 Gene

Paralogs for OR9Q2 Gene

(456) SIMAP similar genes for OR9Q2 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR9Q2 Gene

genes like me logo Genes that share paralogs with OR9Q2: view

Variants for OR9Q2 Gene

Sequence variations from dbSNP and Humsavar for OR9Q2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10896708 -- 58,190,168(+) AATTG(A/G)GGTTC upstream-variant-2KB
rs112782393 -- 58,190,960(+) TGCCT(C/T)TGTTC reference, missense
rs114133139 -- 58,188,975(+) CCTTC(C/T)CCTGG upstream-variant-2KB
rs114696709 -- 58,189,004(+) AATTA(A/G)GGTGT upstream-variant-2KB
rs116035822 -- 58,190,520(+) GTGAC(A/G)GAGTT reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for OR9Q2 Gene

Variant ID Type Subtype PubMed ID
nsv832165 CNV gain 17160897
nsv832166 CNV gain+loss 17160897

Variation tolerance for OR9Q2 Gene

Residual Variation Intolerance Score: 45.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 9.22; 88.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR9Q2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR9Q2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR9Q2 Gene

Disorders for OR9Q2 Gene

Relevant External Links for OR9Q2

Genetic Association Database (GAD)
OR9Q2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR9Q2

No disorders were found for OR9Q2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR9Q2 Gene

Publications for OR9Q2 Gene

  1. Genome-wide association study of electrocardiographic and heart rate variability traits: the Framingham Heart Study. (PMID: 17903306) Newton-Cheh C. … Larson M.G. (BMC Med. Genet. 2007) 46 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR9Q2 Gene

Sources for OR9Q2 Gene

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