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Aliases for OR9K2 Gene

Aliases for OR9K2 Gene

  • Olfactory Receptor, Family 9, Subfamily K, Member 2 2 3
  • Olfactory Receptor OR12-2 3 4
  • Olfactory Receptor 9K2 3
  • OR12-2 3

External Ids for OR9K2 Gene

Summaries for OR9K2 Gene

Entrez Gene Summary for OR9K2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9K2 Gene

OR9K2 (Olfactory Receptor, Family 9, Subfamily K, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR9K2 Gene

  • Odorant receptor.

Gene Wiki entry for OR9K2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9K2 Gene

Genomics for OR9K2 Gene

Genomic Location for OR9K2 Gene

Start:
55,129,681 bp from pter
End:
55,130,802 bp from pter
Size:
1,122 bases
Orientation:
Plus strand

Genomic View for OR9K2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR9K2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9K2 Gene

Regulatory Elements for OR9K2 Gene

Proteins for OR9K2 Gene

  • Protein details for OR9K2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGE7-OR9K2_HUMAN
    Recommended name:
    Olfactory receptor 9K2
    Protein Accession:
    Q8NGE7
    Secondary Accessions:
    • B9EH19
    • Q6IFD6

    Protein attributes for OR9K2 Gene

    Size:
    335 amino acids
    Molecular mass:
    37746 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC06080.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR9K2 Gene

Proteomics data for OR9K2 Gene at MOPED

Post-translational modifications for OR9K2 Gene

  • Glycosylation at Asn30 and Asn114

Other Protein References for OR9K2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for OR9K2 Gene

Domains for OR9K2 Gene

Gene Families for OR9K2 Gene

HGNC:
  • OR9 :GPCR / Class A : Olfactory receptors

Protein Domains for OR9K2 Gene

UniProtKB/Swiss-Prot:

OR9K2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q8NGE7
genes like me logo Genes that share domains with OR9K2: view

Function for OR9K2 Gene

Molecular function for OR9K2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR9K2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR9K2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR9K2 Gene

Localization for OR9K2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9K2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR9K2 Gene COMPARTMENTS Subcellular localization image for OR9K2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9K2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR9K2: view

Pathways for OR9K2 Gene

genes like me logo Genes that share pathways with OR9K2: view

Pathways by source for OR9K2 Gene

Interacting Proteins for OR9K2 Gene

Gene Ontology (GO) - Biological Process for OR9K2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9K2: view

Transcripts for OR9K2 Gene

mRNA/cDNA for OR9K2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR9K2 Gene

No ASD Table

Relevant External Links for OR9K2 Gene

GeneLoc Exon Structure for
OR9K2
ECgene alternative splicing isoforms for
OR9K2

Expression for OR9K2 Gene

mRNA expression in normal human tissues for OR9K2 Gene

SOURCE GeneReport for Unigene cluster for OR9K2 Gene Hs.553827

genes like me logo Genes that share expressions with OR9K2: view

Orthologs for OR9K2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR9K2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC467017 36
  • 99.4 (n)
  • 98.81 (a)
OR9K2 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 81 (a)
OneToMany
-- 37
  • 84 (a)
OneToMany
-- 37
  • 83 (a)
OneToMany
-- 37
  • 49 (a)
OneToMany
-- 37
  • 82 (a)
OneToMany
-- 37
  • 82 (a)
OneToMany
-- 37
  • 85 (a)
OneToMany
-- 37
  • 85 (a)
OneToMany
LOC511753 36
  • 88.39 (n)
  • 86.58 (a)
dog
(Canis familiaris)
Mammalia -- 37
  • 86 (a)
OneToMany
-- 37
  • 80 (a)
OneToMany
LOC100687255 36
  • 87.43 (n)
  • 88.82 (a)
mouse
(Mus musculus)
Mammalia Olfr825 36
  • 85.27 (n)
  • 89.68 (a)
Olfr825 16
Olfr825 37
  • 87 (a)
OneToMany
Olfr826 37
  • 88 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia OR9K2 37
  • 69 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia OR9K2 37
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Olr1070 36
  • 84.99 (n)
  • 88.75 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 52 (a)
OneToMany
-- 37
  • 43 (a)
OneToMany
Species with no ortholog for OR9K2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR9K2 Gene

ENSEMBL:
Gene Tree for OR9K2 (if available)
TreeFam:
Gene Tree for OR9K2 (if available)

Paralogs for OR9K2 Gene

Selected SIMAP similar genes for OR9K2 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR9K2 Gene

genes like me logo Genes that share paralogs with OR9K2: view

No data available for Paralogs for OR9K2 Gene

Variants for OR9K2 Gene

Sequence variations from dbSNP and Humsavar for OR9K2 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs1478735 -- 55,128,266(-) CCAAA(A/G)ATAAT upstream-variant-2KB
rs1478736 -- 55,128,223(-) TTGAG(A/G)TTACA upstream-variant-2KB
rs1478737 -- 55,128,108(-) ATTTA(C/T)TATAG upstream-variant-2KB
rs7137261 -- 55,130,530(+) ATACA(C/T)TCTAC synonymous-codon, reference
rs7305779 - 55,130,076(+) TATTG(A/C)ACCCA reference, missense

Relevant External Links for OR9K2 Gene

HapMap Linkage Disequilibrium report
OR9K2

No data available for Structural Variations from Database of Genomic Variants (DGV) for OR9K2 Gene

Disorders for OR9K2 Gene

No disorders were found for OR9K2 Gene.

No data available for UniProtKB/Swiss-Prot for OR9K2 Gene

Publications for OR9K2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia. (PMID: 24152035) Goodbourn P.T. … Mollon J.D. (Genes Brain Behav. 2014) 3
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR9K2 Gene

Sources for OR9K2 Gene

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