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Aliases for OR9K2 Gene

Aliases for OR9K2 Gene

  • Olfactory Receptor Family 9 Subfamily K Member 2 2 3 5
  • Olfactory Receptor OR12-2 3 4
  • Olfactory Receptor, Family 9, Subfamily K, Member 2 2
  • Olfactory Receptor 9K2 3
  • OR12-2 3

External Ids for OR9K2 Gene

Previous GeneCards Identifiers for OR9K2 Gene

  • GC12U990185
  • GC12P053812
  • GC12P055523

Summaries for OR9K2 Gene

Entrez Gene Summary for OR9K2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9K2 Gene

OR9K2 (Olfactory Receptor Family 9 Subfamily K Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding.

UniProtKB/Swiss-Prot for OR9K2 Gene

  • Odorant receptor.

Gene Wiki entry for OR9K2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9K2 Gene

Genomics for OR9K2 Gene

Regulatory Elements for OR9K2 Gene

Enhancers for OR9K2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12F055101 0.2 Ensembl 11.6 -27.7 -27737 0.5 OR9K2 NEUROD4 OR9K1P PIR43661
GH12F055167 0.5 Ensembl 10.8 +37.8 37820 0.2 ZSCAN29 OR9K2 OR10A7 OR9R1P OR10U1P
GH12F055020 0.3 FANTOM5 7.2 -108.8 -108832 0.0 TFAP4 NFIA GABPB1 NR2F6 OR6C3 OR6C65 OR9K2 OR6C75 NEUROD4 OR6C6 OR6C2 OR10A7 OR6C74 OR6C76
GH12F055630 0.4 FANTOM5 2.4 +499.6 499602 0.0 MMP19 OR6C4 OR10P1 OR6C65 ZC3H10 OR6C74 OR9K2 OR6C3 OR6C2 OR6C6
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR9K2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR9K2 Gene

55,129,681 bp from pter
55,130,802 bp from pter
1,122 bases
Plus strand

Genomic View for OR9K2 Gene

Genes around OR9K2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR9K2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR9K2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9K2 Gene

Proteins for OR9K2 Gene

  • Protein details for OR9K2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 9K2
    Protein Accession:
    Secondary Accessions:
    • B9EH19
    • Q6IFD6

    Protein attributes for OR9K2 Gene

    335 amino acids
    Molecular mass:
    37746 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAC06080.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR9K2 Gene

Post-translational modifications for OR9K2 Gene

  • Glycosylation at Asn 30 and Asn 114
  • Modification sites at PhosphoSitePlus

Other Protein References for OR9K2 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9K2 Gene

Domains & Families for OR9K2 Gene

Gene Families for OR9K2 Gene

Protein Domains for OR9K2 Gene

Suggested Antigen Peptide Sequences for OR9K2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9K2: view

Function for OR9K2 Gene

Molecular function for OR9K2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR9K2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR9K2: view

Phenotypes for OR9K2 Gene

GenomeRNAi human phenotypes for OR9K2:
genes like me logo Genes that share phenotypes with OR9K2: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR9K2 Gene

Localization for OR9K2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9K2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR9K2 Gene COMPARTMENTS Subcellular localization image for OR9K2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9K2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR9K2: view

Pathways & Interactions for OR9K2 Gene

genes like me logo Genes that share pathways with OR9K2: view

Pathways by source for OR9K2 Gene

Gene Ontology (GO) - Biological Process for OR9K2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9K2: view

No data available for SIGNOR curated interactions for OR9K2 Gene

Transcripts for OR9K2 Gene

mRNA/cDNA for OR9K2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR9K2 Gene

No ASD Table

Relevant External Links for OR9K2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR9K2 Gene

mRNA expression in normal human tissues for OR9K2 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR9K2 Gene:


SOURCE GeneReport for Unigene cluster for OR9K2 Gene:

genes like me logo Genes that share expression patterns with OR9K2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR9K2 Gene

Orthologs for OR9K2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR9K2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC467017 34
  • 99.4 (n)
OR9K2 35
  • 99 (a)
(Bos Taurus)
Mammalia LOC511753 34
  • 88.39 (n)
-- 35
  • 85 (a)
-- 35
  • 85 (a)
-- 35
  • 84 (a)
-- 35
  • 83 (a)
-- 35
  • 82 (a)
-- 35
  • 82 (a)
-- 35
  • 81 (a)
-- 35
  • 49 (a)
(Mus musculus)
Mammalia Or9k2b 55 Olfr826 16 35
  • 88 (a)
Or9k2 55 Olfr825 34 35
  • 85.27 (n)
(Canis familiaris)
Mammalia LOC100687255 34
  • 87.43 (n)
-- 35
  • 86 (a)
-- 35
  • 80 (a)
(Rattus norvegicus)
Mammalia Olr1070 34
  • 84.99 (n)
(Monodelphis domestica)
Mammalia OR9K2 35
  • 69 (a)
(Ornithorhynchus anatinus)
Mammalia OR9K2 35
  • 63 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 52 (a)
-- 35
  • 43 (a)
Species where no ortholog for OR9K2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR9K2 Gene

Gene Tree for OR9K2 (if available)
Gene Tree for OR9K2 (if available)

Paralogs for OR9K2 Gene

(455) SIMAP similar genes for OR9K2 Gene using alignment to 1 proteins: Pseudogenes for OR9K2 Gene

genes like me logo Genes that share paralogs with OR9K2: view

No data available for Paralogs for OR9K2 Gene

Variants for OR9K2 Gene

Sequence variations from dbSNP and Humsavar for OR9K2 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs11171306 -- 55,127,955(+) aactt(G/T)tccaa upstream-variant-2KB
rs11171307 -- 55,129,322(+) GTAGG(C/T)TTTTT upstream-variant-2KB
rs11171308 -- 55,129,396(+) ACTTG(A/G)CTACT upstream-variant-2KB
rs11171309 -- 55,129,630(+) AAGAA(A/C)TAAGA upstream-variant-2KB
rs112782622 -- 55,130,399(+) TTCAG(A/C/G)GACTG reference, synonymous-codon, missense

Structural Variations from Database of Genomic Variants (DGV) for OR9K2 Gene

Variant ID Type Subtype PubMed ID
nsv1048657 CNV gain 25217958
nsv1054634 CNV gain 25217958
nsv559001 CNV loss 21841781

Variation tolerance for OR9K2 Gene

Residual Variation Intolerance Score: 86.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 19.51; 98.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR9K2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR9K2 Gene

Disorders for OR9K2 Gene

Relevant External Links for OR9K2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR9K2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR9K2 Gene

Publications for OR9K2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. Variants in the 1q21 risk region are associated with a visual endophenotype of autism and schizophrenia. (PMID: 24152035) Goodbourn P.T. … Mollon J.D. (Genes Brain Behav. 2014) 3 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR9K2 Gene

Sources for OR9K2 Gene

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