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Aliases for OR9I1 Gene

Aliases for OR9I1 Gene

  • Olfactory Receptor Family 9 Subfamily I Member 1 2 3 5
  • Olfactory Receptor OR11-228 3 4
  • Olfactory Receptor, Family 9, Subfamily I, Member 1 2
  • Olfactory Receptor 9I1 3
  • OR11-228 3

External Ids for OR9I1 Gene

Previous GeneCards Identifiers for OR9I1 Gene

  • GC11U990324
  • GC11M057662
  • GC11M057642
  • GC11M057887

Summaries for OR9I1 Gene

Entrez Gene Summary for OR9I1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9I1 Gene

OR9I1 (Olfactory Receptor Family 9 Subfamily I Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is OR9Q2.

UniProtKB/Swiss-Prot for OR9I1 Gene

  • Odorant receptor.

Gene Wiki entry for OR9I1 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9I1 Gene

Genomics for OR9I1 Gene

Regulatory Elements for OR9I1 Gene

Enhancers for OR9I1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F057946 0.6 FANTOM5 5.5 +173.0 173010 0.0 RFX1 OR10W1 OR10Q1 OR9Q2 OR5B2 OR9Q1 OR5B12 MED19 OR5B3 OR1S1 OR9I1
GH11F058033 0.3 FANTOM5 1.3 +85.5 85482 0.3 OR6Q1 OR1S1 OR5B12 OR9I1 ENSG00000255146
GH11F057637 1.2 FANTOM5 ENCODE 1.3 +479.9 479930 4.5 HDGF PKNOX1 ARID4B SIN3A GLI4 ZNF48 ETS1 YY1 SLC30A9 GLIS2 UBE2L6 RPS4XP13 SERPING1 MED19 TIMM10 ENSG00000254602 PRG3 YPEL4 OR9Q1 OR9I1
GH11F058133 0.6 ENCODE 0.4 -14.4 -14380 0.2 HDAC1 PKNOX1 TBL1XR1 RAD21 GATA2 SCRT2 ZBTB11 NCOA1 MBD2 KLF16 OR9Q2 OR9I1 OR9I2P
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR9I1 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR9I1 Gene

Chromosome:
11
Start:
58,118,500 bp from pter
End:
58,119,444 bp from pter
Size:
945 bases
Orientation:
Minus strand

Genomic View for OR9I1 Gene

Genes around OR9I1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR9I1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR9I1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9I1 Gene

Proteins for OR9I1 Gene

  • Protein details for OR9I1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGQ6-OR9I1_HUMAN
    Recommended name:
    Olfactory receptor 9I1
    Protein Accession:
    Q8NGQ6
    Secondary Accessions:
    • Q6IFH0
    • Q96RA8

    Protein attributes for OR9I1 Gene

    Size:
    314 amino acids
    Molecular mass:
    34908 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR9I1 Gene

Post-translational modifications for OR9I1 Gene

  • Glycosylation at Asn 5
  • Modification sites at PhosphoSitePlus

Other Protein References for OR9I1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9I1 Gene

Domains & Families for OR9I1 Gene

Gene Families for OR9I1 Gene

Protein Domains for OR9I1 Gene

Suggested Antigen Peptide Sequences for OR9I1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGQ6

UniProtKB/Swiss-Prot:

OR9I1_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9I1: view

Function for OR9I1 Gene

Molecular function for OR9I1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR9I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR9I1: view

Phenotypes for OR9I1 Gene

GenomeRNAi human phenotypes for OR9I1:
genes like me logo Genes that share phenotypes with OR9I1: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR9I1 Gene

Localization for OR9I1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9I1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR9I1 Gene COMPARTMENTS Subcellular localization image for OR9I1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR9I1: view

Pathways & Interactions for OR9I1 Gene

genes like me logo Genes that share pathways with OR9I1: view

Pathways by source for OR9I1 Gene

Interacting Proteins for OR9I1 Gene

Gene Ontology (GO) - Biological Process for OR9I1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IEA --
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IEA --
GO:0050896 response to stimulus IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9I1: view

No data available for SIGNOR curated interactions for OR9I1 Gene

Transcripts for OR9I1 Gene

mRNA/cDNA for OR9I1 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR9I1 Gene

No ASD Table

Relevant External Links for OR9I1 Gene

GeneLoc Exon Structure for
OR9I1
ECgene alternative splicing isoforms for
OR9I1

Expression for OR9I1 Gene

mRNA expression in normal human tissues for OR9I1 Gene

NURSA nuclear receptor signaling pathways regulating expression of OR9I1 Gene:

OR9I1

SOURCE GeneReport for Unigene cluster for OR9I1 Gene:

Hs.632122
genes like me logo Genes that share expression patterns with OR9I1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR9I1 Gene

Orthologs for OR9I1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR9I1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466593 34
  • 99.26 (n)
OR9I1 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC483485 34
  • 86.94 (n)
OR9I1 35
  • 84 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC524304 34
  • 83.01 (n)
OR9I1 35
  • 81 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Or9i1b 55 Olfr1505 16 35
  • 82 (a)
Or9i1 55 Olfr1502 34 35
  • 80.6 (n)
Or9i14 55 Olfr1499 35
  • 79 (a)
OneToMany
Or9i13-ps 55 Olfr1498-ps1
  • chr19:13,804,434-13,805,325
Or9i15-ps 55 Olfr1503-ps1
  • chr19:13,877,451-13,878,247
rat
(Rattus norvegicus)
Mammalia Olr384 34
  • 80.57 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 75 (a)
OneToMany
-- 35
  • 72 (a)
OneToMany
-- 35
  • 71 (a)
OneToMany
OPOR158 35
  • 68 (a)
OneToMany
Species where no ortholog for OR9I1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR9I1 Gene

ENSEMBL:
Gene Tree for OR9I1 (if available)
TreeFam:
Gene Tree for OR9I1 (if available)

Paralogs for OR9I1 Gene

Paralogs for OR9I1 Gene

(441) SIMAP similar genes for OR9I1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR9I1 Gene

genes like me logo Genes that share paralogs with OR9I1: view

Variants for OR9I1 Gene

Sequence variations from dbSNP and Humsavar for OR9I1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs386352342 Uncertain significance 58,119,227(-) CTGTT(A/G)CACCT intron-variant, reference, missense
rs111567855 -- 58,121,428(+) GACCT(A/G)CCAGA intron-variant, upstream-variant-2KB
rs111926666 -- 58,120,168(+) ATTTT(A/G)TATTT intron-variant, upstream-variant-2KB
rs11229259 -- 58,119,810(+) GTTGC(C/T)GTATG intron-variant, upstream-variant-2KB
rs112968757 -- 58,119,958(+) CTTTC(A/G)CAAGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR9I1 Gene

Variant ID Type Subtype PubMed ID
nsv832165 CNV gain 17160897
nsv832166 CNV gain+loss 17160897

Variation tolerance for OR9I1 Gene

Residual Variation Intolerance Score: 87.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.43; 27.99% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for OR9I1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR9I1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR9I1 Gene

Disorders for OR9I1 Gene

Relevant External Links for OR9I1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR9I1

No disorders were found for OR9I1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR9I1 Gene

Publications for OR9I1 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  2. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4 64

Products for OR9I1 Gene

Sources for OR9I1 Gene

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