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Aliases for OR9G4 Gene

Aliases for OR9G4 Gene

  • Olfactory Receptor, Family 9, Subfamily G, Member 4 2 3
  • Olfactory Receptor OR11-216 3 4
  • Olfactory Receptor 9G4 3
  • OR11-216 3

External Ids for OR9G4 Gene

Previous GeneCards Identifiers for OR9G4 Gene

  • GC11U990392
  • GC11M056286
  • GC11M056266
  • GC11M056510

Summaries for OR9G4 Gene

Entrez Gene Summary for OR9G4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9G4 Gene

OR9G4 (Olfactory Receptor, Family 9, Subfamily G, Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR9G1.

UniProtKB/Swiss-Prot for OR9G4 Gene

  • Odorant receptor.

Gene Wiki entry for OR9G4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9G4 Gene

Genomics for OR9G4 Gene

Regulatory Elements for OR9G4 Gene

Genomic Location for OR9G4 Gene

Start:
56,742,827 bp from pter
End:
56,743,811 bp from pter
Size:
985 bases
Orientation:
Minus strand

Genomic View for OR9G4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR9G4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9G4 Gene

Proteins for OR9G4 Gene

  • Protein details for OR9G4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGQ1-OR9G4_HUMAN
    Recommended name:
    Olfactory receptor 9G4
    Protein Accession:
    Q8NGQ1
    Secondary Accessions:
    • Q6IF62
    • Q96RA9

    Protein attributes for OR9G4 Gene

    Size:
    327 amino acids
    Molecular mass:
    36344 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC05959.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for OR9G4 Gene

Proteomics data for OR9G4 Gene at MOPED

Post-translational modifications for OR9G4 Gene

Other Protein References for OR9G4 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9G4 Gene

Domains for OR9G4 Gene

Gene Families for OR9G4 Gene

HGNC:
  • OR9 :GPCR / Class A : Olfactory receptors

Protein Domains for OR9G4 Gene

Suggested Antigen Peptide Sequences for OR9G4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NGQ1

UniProtKB/Swiss-Prot:

OR9G4_HUMAN :
  • Q8NGQ1
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9G4: view

Function for OR9G4 Gene

Molecular function for OR9G4 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR9G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR9G4: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR9G4

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR9G4 Gene

Localization for OR9G4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9G4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR9G4 Gene COMPARTMENTS Subcellular localization image for OR9G4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR9G4: view

Pathways for OR9G4 Gene

genes like me logo Genes that share pathways with OR9G4: view

Pathways by source for OR9G4 Gene

Interacting Proteins for OR9G4 Gene

Gene Ontology (GO) - Biological Process for OR9G4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9G4: view

Transcripts for OR9G4 Gene

mRNA/cDNA for OR9G4 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR9G4

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for OR9G4
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR9G4 Gene

No ASD Table

Relevant External Links for OR9G4 Gene

GeneLoc Exon Structure for
OR9G4
ECgene alternative splicing isoforms for
OR9G4

Expression for OR9G4 Gene

mRNA expression in normal human tissues for OR9G4 Gene

SOURCE GeneReport for Unigene cluster for OR9G4 Gene Hs.554521

genes like me logo Genes that share expressions with OR9G4: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for OR9G4 Gene

Orthologs for OR9G4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR9G4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC466578 35
  • 98.98 (n)
  • 98.47 (a)
OR9G4 36
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 36
  • 84 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
LOC506891 35
  • 84.57 (n)
  • 85.85 (a)
dog
(Canis familiaris)
Mammalia OR9G4 35
  • 88.21 (n)
  • 90.68 (a)
OR9G4 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Olfr1006 35
  • 84.94 (n)
  • 87.18 (a)
Olfr1006 16
Olfr1006 36
  • 87 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 83 (a)
OneToMany
-- 36
  • 79 (a)
OneToMany
-- 36
  • 80 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Olr450 35
  • 84.08 (n)
  • 87.18 (a)
Species with no ortholog for OR9G4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR9G4 Gene

ENSEMBL:
Gene Tree for OR9G4 (if available)
TreeFam:
Gene Tree for OR9G4 (if available)

Paralogs for OR9G4 Gene

Paralogs for OR9G4 Gene

Selected SIMAP similar genes for OR9G4 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for OR9G4 Gene

genes like me logo Genes that share paralogs with OR9G4: view

Variants for OR9G4 Gene

Sequence variations from dbSNP and Humsavar for OR9G4 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs7114266 -- 56,744,896(+) AGCAC(A/G)CCCAG upstream-variant-2KB
rs7115637 -- 56,745,246(+) AGTAT(C/G)TTGCT upstream-variant-2KB
rs12417975 -- 56,745,419(+) ATCTG(A/G)AAATT upstream-variant-2KB
rs60711098 -- 56,744,792(+) CACTC(C/T)GTCAC upstream-variant-2KB
rs61902481 -- 56,745,186(+) TAAAT(A/T)AATAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR9G4 Gene

Variant ID Type Subtype PubMed ID
nsv468577 CNV Gain 19166990

Relevant External Links for OR9G4 Gene

HapMap Linkage Disequilibrium report
OR9G4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR9G4 Gene

Disorders for OR9G4 Gene

Relevant External Links for OR9G4

Genetic Association Database (GAD)
OR9G4
genes like me logo Genes that share disorders with OR9G4: view

No data available for UniProtKB/Swiss-Prot for OR9G4 Gene

Publications for OR9G4 Gene

  1. DEFOG: a practical scheme for deciphering families of genes. (PMID: 12213199) Fuchs T. … Shamir R. (Genomics 2002) 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PMID: 17903294) Yang Q. … O'Donnell C.J. (BMC Med. Genet. 2007) 3 48
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4

Products for OR9G4 Gene

Sources for OR9G4 Gene

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