Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR9A4 Gene

Aliases for OR9A4 Gene

  • Olfactory Receptor Family 9 Subfamily A Member 4 2 3 5
  • Olfactory Receptor, Family 9, Subfamily A, Member 4 2
  • Olfactory Receptor OR7-1 4

External Ids for OR9A4 Gene

Previous GeneCards Identifiers for OR9A4 Gene

  • GC07U990309
  • GC07P141026
  • GC07P141071
  • GC07P141265
  • GC07P141619
  • GC07P141622
  • GC07P142619
  • GC07P142928

Summaries for OR9A4 Gene

Entrez Gene Summary for OR9A4 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9A4 Gene

OR9A4 (Olfactory Receptor Family 9 Subfamily A Member 4) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR6S1.

UniProtKB/Swiss-Prot for OR9A4 Gene

  • Odorant receptor.

Gene Wiki entry for OR9A4 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9A4 Gene

Genomics for OR9A4 Gene

Regulatory Elements for OR9A4 Gene

Enhancers for OR9A4 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around OR9A4 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR9A4 Gene

141,873,479 bp from pter
141,986,420 bp from pter
112,942 bases
Plus strand

Genomic View for OR9A4 Gene

Genes around OR9A4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR9A4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR9A4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9A4 Gene

Proteins for OR9A4 Gene

  • Protein details for OR9A4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 9A4
    Protein Accession:
    Secondary Accessions:
    • B9EGV6
    • Q6IFI4

    Protein attributes for OR9A4 Gene

    314 amino acids
    Molecular mass:
    35758 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR9A4 Gene

Proteomics data for OR9A4 Gene at MOPED

Post-translational modifications for OR9A4 Gene

  • Glycosylation at Asn 4 and Asn 190
  • Modification sites at PhosphoSitePlus

Other Protein References for OR9A4 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9A4 Gene

Domains & Families for OR9A4 Gene

Gene Families for OR9A4 Gene

Protein Domains for OR9A4 Gene

Suggested Antigen Peptide Sequences for OR9A4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9A4: view

Function for OR9A4 Gene

Molecular function for OR9A4 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.
genes like me logo Genes that share phenotypes with OR9A4: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR9A4 Gene

Localization for OR9A4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9A4 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR9A4 Gene COMPARTMENTS Subcellular localization image for OR9A4 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9A4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR9A4: view

Pathways & Interactions for OR9A4 Gene

genes like me logo Genes that share pathways with OR9A4: view

Pathways by source for OR9A4 Gene

Interacting Proteins for OR9A4 Gene

Gene Ontology (GO) - Biological Process for OR9A4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9A4: view

No data available for SIGNOR curated interactions for OR9A4 Gene

Drugs & Compounds for OR9A4 Gene

No Compound Related Data Available

Transcripts for OR9A4 Gene

mRNA/cDNA for OR9A4 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR9A4 Gene

Olfactory receptor, family 9, subfamily A, member 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR9A4 Gene

No ASD Table

Relevant External Links for OR9A4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR9A4 Gene

mRNA expression in normal human tissues for OR9A4 Gene

SOURCE GeneReport for Unigene cluster for OR9A4 Gene Hs.690171

genes like me logo Genes that share expression patterns with OR9A4: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR9A4 Gene

Orthologs for OR9A4 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR9A4 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR9A4 35
  • 86.84 (n)
  • 87.26 (a)
OR9A4 36
  • 87 (a)
(Canis familiaris)
Mammalia LOC607362 35
  • 86.62 (n)
  • 88.85 (a)
-- 36
  • 89 (a)
-- 36
  • 85 (a)
-- 36
  • 85 (a)
-- 36
  • 89 (a)
(Mus musculus)
Mammalia Olfr460 35
  • 84.39 (n)
  • 84.39 (a)
Olfr460 16
Olfr460 36
  • 84 (a)
(Pan troglodytes)
Mammalia LOC472536 35
  • 99.15 (n)
  • 98.09 (a)
OR9A4 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Olr799 35
  • 84.18 (n)
  • 83.44 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 69 (a)
(Danio rerio)
Actinopterygii or101-1 36
  • 35 (a)
Species with no ortholog for OR9A4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OR9A4 Gene

Gene Tree for OR9A4 (if available)
Gene Tree for OR9A4 (if available)

Paralogs for OR9A4 Gene

Paralogs for OR9A4 Gene

(440) SIMAP similar genes for OR9A4 Gene using alignment to 1 proteins: Pseudogenes for OR9A4 Gene

genes like me logo Genes that share paralogs with OR9A4: view

Variants for OR9A4 Gene

Sequence variations from dbSNP and Humsavar for OR9A4 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs873818 -- 141,888,255(+) ACATC(G/T)TTTAA intron-variant
rs941255 -- 141,890,066(-) ATTTT(C/G)TCTTC intron-variant
rs994808 -- 141,911,091(+) ACATA(A/C)ATGAG intron-variant
rs994809 -- 141,911,485(+) TGGTG(C/T)TACTG intron-variant
rs6950696 -- 141,910,174(+) TCCAG(C/G)CTTTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for OR9A4 Gene

Variant ID Type Subtype PubMed ID
nsv831161 CNV Loss 17160897
nsv5974 CNV Loss 18451855

Variation tolerance for OR9A4 Gene

Residual Variation Intolerance Score: 73.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.53; 44.19% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR9A4 Gene

Disorders for OR9A4 Gene

Relevant External Links for OR9A4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR9A4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR9A4 Gene

Publications for OR9A4 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 67
  2. Genetic variants associated with disordered eating. (PMID: 23568457) Wade T.D. … Martin N.G. (Int J Eat Disord 2013) 3
  3. Human chromosome 7: DNA sequence and biology. (PMID: 12690205) Scherer S.W. … Tsui L.-C. (Science 2003) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR9A4 Gene

Sources for OR9A4 Gene