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Aliases for OR9A2 Gene

Aliases for OR9A2 Gene

  • Olfactory Receptor, Family 9, Subfamily A, Member 2 2 3
  • Olfactory Receptor OR7-2 4

External Ids for OR9A2 Gene

Previous GeneCards Identifiers for OR9A2 Gene

  • GC07U990311
  • GC07M142196
  • GC07M142240
  • GC07M142433
  • GC07M142723

Summaries for OR9A2 Gene

Entrez Gene Summary for OR9A2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR9A2 Gene

OR9A2 (Olfactory Receptor, Family 9, Subfamily A, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR9A4.

UniProtKB/Swiss-Prot for OR9A2 Gene

  • Odorant receptor.

Gene Wiki entry for OR9A2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR9A2 Gene

Genomics for OR9A2 Gene

Regulatory Elements for OR9A2 Gene

Genomic Location for OR9A2 Gene

Start:
143,026,158 bp from pter
End:
143,027,195 bp from pter
Size:
1,038 bases
Orientation:
Minus strand

Genomic View for OR9A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR9A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR9A2 Gene

Proteins for OR9A2 Gene

  • Protein details for OR9A2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NGT5-OR9A2_HUMAN
    Recommended name:
    Olfactory receptor 9A2
    Protein Accession:
    Q8NGT5
    Secondary Accessions:
    • B9EH51
    • Q6IF71
    • Q8NGD9

    Protein attributes for OR9A2 Gene

    Size:
    310 amino acids
    Molecular mass:
    35330 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR9A2 Gene

Proteomics data for OR9A2 Gene at MOPED

Post-translational modifications for OR9A2 Gene

  • Glycosylation at Asn4
  • Modification sites at PhosphoSitePlus

Other Protein References for OR9A2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR9A2 Gene

Domains for OR9A2 Gene

Gene Families for OR9A2 Gene

HGNC:
  • OR9 :GPCR / Class A : Olfactory receptors

Protein Domains for OR9A2 Gene

Suggested Antigen Peptide Sequences for OR9A2 Gene

Graphical View of Domain Structure for InterPro Entry

Q8NGT5

UniProtKB/Swiss-Prot:

OR9A2_HUMAN :
  • Q8NGT5
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR9A2: view

Function for OR9A2 Gene

Molecular function for OR9A2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR9A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR9A2: view

Phenotypes for OR9A2 Gene

GenomeRNAi human phenotypes for OR9A2:
genes like me logo Genes that share phenotypes with OR9A2: view

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR9A2 Gene

Localization for OR9A2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR9A2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR9A2 Gene COMPARTMENTS Subcellular localization image for OR9A2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR9A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR9A2: view

Pathways for OR9A2 Gene

genes like me logo Genes that share pathways with OR9A2: view

Pathways by source for OR9A2 Gene

Interacting Proteins for OR9A2 Gene

Gene Ontology (GO) - Biological Process for OR9A2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR9A2: view

Transcripts for OR9A2 Gene

mRNA/cDNA for OR9A2 Gene

(2) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(3) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR9A2 Gene

Olfactory receptor, family 9, subfamily A, member 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR9A2 Gene

No ASD Table

Relevant External Links for OR9A2 Gene

GeneLoc Exon Structure for
OR9A2
ECgene alternative splicing isoforms for
OR9A2

Expression for OR9A2 Gene

mRNA expression in normal human tissues for OR9A2 Gene

mRNA differential expression in normal tissues according to GTEx for OR9A2 Gene

This gene is overexpressed in Brain - Spinal cord (cervical c-1) (16.5), Brain - Substantia nigra (5.6), and Brain - Hippocampus (4.5).

SOURCE GeneReport for Unigene cluster for OR9A2 Gene Hs.553594

genes like me logo Genes that share expressions with OR9A2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein expression and mRNA Expression by UniProt/SwissProt for OR9A2 Gene

Orthologs for OR9A2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for OR9A2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 79 (a)
OneToMany
-- 36
  • 80 (a)
OneToMany
-- 36
  • 80 (a)
OneToMany
LOC614298 35
  • 83.28 (n)
  • 82.3 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 45 (a)
ManyToMany
LOC100686794 35
  • 82.52 (n)
  • 79.8 (a)
mouse
(Mus musculus)
Mammalia Olfr459 35
  • 81.88 (n)
  • 81.88 (a)
Olfr459 16
Olfr459 36
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 67 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia RGD1562066 35
  • 81.66 (n)
  • 82.2 (a)
zebrafish
(Danio rerio)
Actinopterygii or101-1 36
  • 32 (a)
OneToMany
Species with no ortholog for OR9A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for OR9A2 Gene

ENSEMBL:
Gene Tree for OR9A2 (if available)
TreeFam:
Gene Tree for OR9A2 (if available)

Paralogs for OR9A2 Gene

Paralogs for OR9A2 Gene

Selected SIMAP similar genes for OR9A2 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for OR9A2 Gene

genes like me logo Genes that share paralogs with OR9A2: view

Variants for OR9A2 Gene

Sequence variations from dbSNP and Humsavar for OR9A2 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs9885986 - 143,026,975(+) GCAGA(C/T)GTTTA missense, reference
rs11364228 -- 143,028,280(+) CCATG(-/A)GGGCT upstream-variant-2KB
rs34203442 -- 143,027,108(+) TTCAG(C/T)GGCAC reference, missense
rs34687921 -- 143,027,555(+) TGACA(C/T)AAAGG upstream-variant-2KB
rs34967617 -- 143,029,054(+) TGTGT(-/C)TAGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for OR9A2 Gene

Variant ID Type Subtype PubMed ID
dgv2145e1 CNV Complex 17122850
nsv889274 CNV Loss 21882294

Relevant External Links for OR9A2 Gene

HapMap Linkage Disequilibrium report
OR9A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR9A2 Gene

Disorders for OR9A2 Gene

No disorders were found for OR9A2 Gene.

No data available for UniProtKB/Swiss-Prot for OR9A2 Gene

Publications for OR9A2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. Novel human G-protein-coupled receptors. (PMID: 12732197) Vanti W.B. … O'Dowd B.F. (Biochem. Biophys. Res. Commun. 2003) 3
  5. Natural selection on the olfactory receptor gene family in humans and chimpanzees. (PMID: 12908129) Gilad Y. … Paabo S. (Am. J. Hum. Genet. 2003) 3

Products for OR9A2 Gene

Sources for OR9A2 Gene

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