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Aliases for OR8U1 Gene

Aliases for OR8U1 Gene

  • Olfactory Receptor Family 8 Subfamily U Member 1 2 3 5
  • Olfactory Receptor, Family 8, Subfamily U, Member 1 2

External Ids for OR8U1 Gene

Previous GeneCards Identifiers for OR8U1 Gene

  • GC00U903073
  • GC11P055919
  • GC11P055885
  • GC11P056145
  • GC11P056146

Summaries for OR8U1 Gene

Entrez Gene Summary for OR8U1 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR8U1 Gene

OR8U1 (Olfactory Receptor Family 8 Subfamily U Member 1) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and odorant binding. An important paralog of this gene is ENSG00000279961.

UniProtKB/Swiss-Prot for OR8U1 Gene

  • Odorant receptor.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR8U1 Gene

Genomics for OR8U1 Gene

Regulatory Elements for OR8U1 Gene

Genomic Location for OR8U1 Gene

56,375,609 bp from pter
56,376,553 bp from pter
945 bases
Plus strand

Genomic View for OR8U1 Gene

Genes around OR8U1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR8U1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR8U1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR8U1 Gene

Proteins for OR8U1 Gene

  • Protein details for OR8U1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 8U1
    Protein Accession:

    Protein attributes for OR8U1 Gene

    309 amino acids
    Molecular mass:
    35088 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR8U1 Gene

Proteomics data for OR8U1 Gene at MOPED

Post-translational modifications for OR8U1 Gene

Other Protein References for OR8U1 Gene

ENSEMBL proteins:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR8U1 Gene

Domains & Families for OR8U1 Gene

Gene Families for OR8U1 Gene

Protein Domains for OR8U1 Gene

Suggested Antigen Peptide Sequences for OR8U1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR8U1: view

Function for OR8U1 Gene

Molecular function for OR8U1 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR8U1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR8U1: view

Phenotypes for OR8U1 Gene

GenomeRNAi human phenotypes for OR8U1:
genes like me logo Genes that share phenotypes with OR8U1: view

Animal Model Products

CRISPR Products

miRNA for OR8U1 Gene

miRTarBase miRNAs that target OR8U1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for OR8U1 Gene

Localization for OR8U1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR8U1 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR8U1 Gene COMPARTMENTS Subcellular localization image for OR8U1 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR8U1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR8U1: view

Pathways & Interactions for OR8U1 Gene

genes like me logo Genes that share pathways with OR8U1: view

Pathways by source for OR8U1 Gene

Interacting Proteins for OR8U1 Gene

Gene Ontology (GO) - Biological Process for OR8U1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR8U1: view

No data available for SIGNOR curated interactions for OR8U1 Gene

Drugs & Compounds for OR8U1 Gene

No Compound Related Data Available

Transcripts for OR8U1 Gene

mRNA/cDNA for OR8U1 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for OR8U1 Gene

Olfactory receptor, family 8, subfamily U, member 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for OR8U1 Gene

No ASD Table

Relevant External Links for OR8U1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR8U1 Gene

mRNA expression in normal human tissues for OR8U1 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for OR8U1 Gene

SOURCE GeneReport for Unigene cluster for OR8U1 Gene Hs.553618

genes like me logo Genes that share expression patterns with OR8U1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for OR8U1 Gene

Orthologs for OR8U1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR8U1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia OR8U1 35
  • 84.36 (n)
  • 83.82 (a)
OR8U1 36
  • 81 (a)
(Canis familiaris)
Mammalia OR8U1 35
  • 87.38 (n)
  • 89 (a)
OR8U1 36
  • 86 (a)
(Mus musculus)
Mammalia Olfr1044 35
  • 83.71 (n)
  • 86.41 (a)
Olfr1044 16
Olfr1044 36
  • 85 (a)
(Pan troglodytes)
Mammalia LOC466560 35
  • 93.1 (n)
  • 92.23 (a)
OR8U1 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Olr482 35
  • 83.5 (n)
  • 84.79 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 80 (a)
-- 36
  • 79 (a)
-- 36
  • 78 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 56 (a)
Species with no ortholog for OR8U1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR8U1 Gene

Gene Tree for OR8U1 (if available)
Gene Tree for OR8U1 (if available)

Paralogs for OR8U1 Gene

Paralogs for OR8U1 Gene

(457) SIMAP similar genes for OR8U1 Gene using alignment to 1 proteins: Pseudogenes for OR8U1 Gene

genes like me logo Genes that share paralogs with OR8U1: view

Variants for OR8U1 Gene

Sequence variations from dbSNP and Humsavar for OR8U1 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
VAR_053247 -
VAR_053248 -
VAR_053249 -
VAR_053250 -
VAR_053251 -

Structural Variations from Database of Genomic Variants (DGV) for OR8U1 Gene

Variant ID Type Subtype PubMed ID
nsv832161 CNV Gain 17160897
nsv324 CNV Insertion 18451855
nsv511006 CNV Complex 20534489
nsv478256 CNV Insertion 20440878
nsv499490 CNV Gain 21111241

Variation tolerance for OR8U1 Gene

Residual Variation Intolerance Score: 99.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.81; 86.84% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for OR8U1 Gene

Disorders for OR8U1 Gene

Relevant External Links for OR8U1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for OR8U1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR8U1 Gene

Publications for OR8U1 Gene

  1. The diploid genome sequence of an individual human. (PMID: 17803354) Levy S. … Venter J.C. (PLoS Biol. 2007) 3 67

Products for OR8U1 Gene

Sources for OR8U1 Gene