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Aliases for OR8H2 Gene

Aliases for OR8H2 Gene

  • Olfactory Receptor, Family 8, Subfamily H, Member 2 2 3
  • Olfactory Receptor OR11-171 3 4
  • Olfactory Receptor 8H2 3
  • OR11-171 3

External Ids for OR8H2 Gene

Previous GeneCards Identifiers for OR8H2 Gene

  • GC11U990406
  • GC11P055648
  • GC11P055629
  • GC11P055872

Summaries for OR8H2 Gene

Entrez Gene Summary for OR8H2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR8H2 Gene

OR8H2 (Olfactory Receptor, Family 8, Subfamily H, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity. An important paralog of this gene is OR8I2.

UniProtKB/Swiss-Prot for OR8H2 Gene

  • Odorant receptor.

Gene Wiki entry for OR8H2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR8H2 Gene

Genomics for OR8H2 Gene

Regulatory Elements for OR8H2 Gene

Genomic Location for OR8H2 Gene

56,105,018 bp from pter
56,106,055 bp from pter
1,038 bases
Plus strand

Genomic View for OR8H2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR8H2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR8H2 Gene

Proteins for OR8H2 Gene

  • Protein details for OR8H2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Olfactory receptor 8H2
    Protein Accession:
    Secondary Accessions:
    • Q6IFC1

    Protein attributes for OR8H2 Gene

    312 amino acids
    Molecular mass:
    35422 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR8H2 Gene

Proteomics data for OR8H2 Gene at MOPED

Post-translational modifications for OR8H2 Gene

  • Glycosylation at Asn6
  • Modification sites at PhosphoSitePlus

Other Protein References for OR8H2 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:
HORDE protein sequence:

No data available for DME Specific Peptides for OR8H2 Gene

Domains for OR8H2 Gene

Gene Families for OR8H2 Gene

Protein Domains for OR8H2 Gene

Suggested Antigen Peptide Sequences for OR8H2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the G-protein coupled receptor 1 family.
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR8H2: view

Function for OR8H2 Gene

Molecular function for OR8H2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR8H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IBA --
GO:0004984 olfactory receptor activity IBA --
GO:0005549 odorant binding IBA --
genes like me logo Genes that share ontologies with OR8H2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR8H2

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR8H2 Gene

Localization for OR8H2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR8H2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for OR8H2 Gene COMPARTMENTS Subcellular localization image for OR8H2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR8H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0005887 integral component of plasma membrane IBA --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with OR8H2: view

Pathways for OR8H2 Gene

genes like me logo Genes that share pathways with OR8H2: view

Pathways by source for OR8H2 Gene

Interacting Proteins for OR8H2 Gene

Gene Ontology (GO) - Biological Process for OR8H2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IBA --
GO:0007608 sensory perception of smell IBA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR8H2: view

Transcripts for OR8H2 Gene

mRNA/cDNA for OR8H2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for OR8H2

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR8H2 Gene

No ASD Table

Relevant External Links for OR8H2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for OR8H2 Gene

mRNA expression in normal human tissues for OR8H2 Gene

Protein differential expression in normal tissues for OR8H2 Gene

This gene is overexpressed in Tlymphocyte (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for OR8H2 Gene

SOURCE GeneReport for Unigene cluster for OR8H2 Gene Hs.553744

genes like me logo Genes that share expressions with OR8H2: view

Expression partners for OR8H2 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for OR8H2 Gene

Orthologs for OR8H2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR8H2 Gene

Organism Taxonomy Gene Similarity Type Details
(Mus musculus)
Mammalia Olfr1100 35
  • 76.1 (n)
  • 70.74 (a)
Olfr1097 36
  • 69 (a)
Olfr1098 36
  • 69 (a)
Olfr1099 36
  • 70 (a)
Olfr1100 36
  • 69 (a)
(Pan troglodytes)
Mammalia LOC466546 35
  • 98.82 (n)
  • 97.12 (a)
OR8H2 36
  • 97 (a)
(Rattus norvegicus)
Mammalia Olr526 35
  • 76.96 (n)
  • 72.67 (a)
(Bos Taurus)
Mammalia -- 36
  • 71 (a)
-- 36
  • 71 (a)
(Canis familiaris)
Mammalia -- 36
  • 76 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 56 (a)
-- 36
  • 54 (a)
Species with no ortholog for OR8H2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR8H2 Gene

Gene Tree for OR8H2 (if available)
Gene Tree for OR8H2 (if available)

Paralogs for OR8H2 Gene

(454) SIMAP similar genes for OR8H2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with OR8H2: view

Variants for OR8H2 Gene

Sequence variations from dbSNP and Humsavar for OR8H2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs112501673 -- 56,104,896(+) GGCTG(A/G)AATGC upstream-variant-2KB
rs112970004 -- 56,103,612(+) TGGTC(C/T)CCAGG upstream-variant-2KB
rs141308613 -- 56,105,552(+) TACGA(C/T)TCAAA reference, synonymous-codon
rs141305814 -- 56,105,624(+) TACAA(A/C)ACCGA missense, reference
rs141204034 -- 56,105,361(+) CCTTC(C/T)TGGGT synonymous-codon, reference

Structural Variations from Database of Genomic Variants (DGV) for OR8H2 Gene

Variant ID Type Subtype PubMed ID
esv2751030 CNV Gain 17911159
nsv521440 CNV Loss 19592680
nsv832160 CNV Gain 17160897
nsv468575 CNV Loss 19166990
esv2661122 CNV Deletion 23128226

Relevant External Links for OR8H2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for OR8H2 Gene

Disorders for OR8H2 Gene

Relevant External Links for OR8H2

Genetic Association Database (GAD)

No disorders were found for OR8H2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for OR8H2 Gene

Publications for OR8H2 Gene

  1. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  2. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PMID: 23824909) Chen Y. … Ge F. (Mol. Cell Proteomics 2013) 3
  3. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. (PMID: 20235792) Uhl G.R. … MunafA^ M.R. (Pharmacogenomics 2010) 48

Products for OR8H2 Gene

Sources for OR8H2 Gene

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