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Aliases for OR8G2 Gene

Aliases for OR8G2 Gene

  • Olfactory Receptor, Family 8, Subfamily G, Member 2 2 3
  • Olfactory Receptor OR11-292 3 4
  • Olfactory Receptor TPCR120 3 4
  • Olfactory Receptor 8G4 3 4
  • OR8G2P 3 4
  • OR8G4 3 4
  • Olfactory Receptor, Family 8, Subfamily G, Member 2 Pseudogene 2
  • Olfactory Receptor, Family 8, Subfamily G, Member 4 3
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor OR11-297 3
  • Olfactory Receptor 8G2 3
  • HSTPCR120 3
  • TPCR120 3
  • ORL206 3
  • ORL486 3

External Ids for OR8G2 Gene

Previous Symbols for OR8G2 Gene

  • OR8G2P
  • OR8G4

Summaries for OR8G2 Gene

Entrez Gene Summary for OR8G2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR8G2 Gene

OR8G2 (Olfactory Receptor, Family 8, Subfamily G, Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR8G2 Gene

  • Odorant receptor.

Gene Wiki entry for OR8G2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR8G2 Gene

Genomics for OR8G2 Gene

Genomic Location for OR8G2 Gene

Start:
124,224,693 bp from pter
End:
124,225,639 bp from pter
Size:
947 bases
Orientation:
Plus strand

Genomic View for OR8G2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for OR8G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR8G2 Gene

Regulatory Elements for OR8G2 Gene

Proteins for OR8G2 Gene

  • Protein details for OR8G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IF36-OR8G2_HUMAN
    Recommended name:
    Olfactory receptor 8G2
    Protein Accession:
    Q6IF36
    Secondary Accessions:
    • Q15614
    • Q6IF38

    Protein attributes for OR8G2 Gene

    Size:
    304 amino acids
    Molecular mass:
    33950 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR8G2 Gene

Proteomics data for OR8G2 Gene at MOPED

Post-translational modifications for OR8G2 Gene

No Post-translational modifications

Other Protein References for OR8G2 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for OR8G2 Gene

Domains for OR8G2 Gene

Gene Families for OR8G2 Gene

HGNC:
  • OR8 :GPCR / Class A : Olfactory receptors

Protein Domains for OR8G2 Gene

UniProtKB/Swiss-Prot:

OR8G2_HUMAN
Family:
  • Belongs to the G-protein coupled receptor 1 family.:
    • Q6IF36
genes like me logo Genes that share domains with OR8G2: view

Function for OR8G2 Gene

Molecular function for OR8G2 Gene

UniProtKB/Swiss-Prot Function: Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR8G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity NAS 9119360
genes like me logo Genes that share ontologies with OR8G2: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for OR8G2 Gene

Localization for OR8G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR8G2 Gene

Cell membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for OR8G2 Gene COMPARTMENTS Subcellular localization image for OR8G2 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for OR8G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane NAS 9119360
genes like me logo Genes that share ontologies with OR8G2: view

Pathways for OR8G2 Gene

genes like me logo Genes that share pathways with OR8G2: view

Pathways by source for OR8G2 Gene

1 BioSystems pathway for OR8G2 Gene
1 KEGG pathway for OR8G2 Gene

Interacting Proteins for OR8G2 Gene

Gene Ontology (GO) - Biological Process for OR8G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0007608 sensory perception of smell NAS 9119360
GO:0050911 detection of chemical stimulus involved in sensory perception of smell NAS 9119360
genes like me logo Genes that share ontologies with OR8G2: view

Transcripts for OR8G2 Gene

mRNA/cDNA for OR8G2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for OR8G2 Gene

No ASD Table

Relevant External Links for OR8G2 Gene

GeneLoc Exon Structure for
OR8G2
ECgene alternative splicing isoforms for
OR8G2

Expression for OR8G2 Gene

mRNA expression in normal human tissues for OR8G2 Gene

mRNA differential expression in normal tissues according to GTEx for OR8G2 Gene

This gene is overexpressed in Testis (43.9) and Cervix - Endocervix (9.1).

SOURCE GeneReport for Unigene cluster for OR8G2 Gene Hs.381319

genes like me logo Genes that share expressions with OR8G2: view

Orthologs for OR8G2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR8G2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC513062 36
  • 85.48 (n)
  • 86.41 (a)
dog
(Canis familiaris)
Mammalia LOC100687661 36
  • 86.64 (n)
  • 86.06 (a)
mouse
(Mus musculus)
Mammalia Olfr229 36
  • 83.51 (n)
  • 85.02 (a)
Olfr229 16
Species with no ortholog for OR8G2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR8G2 Gene

ENSEMBL:
Gene Tree for OR8G2 (if available)
TreeFam:
Gene Tree for OR8G2 (if available)

Paralogs for OR8G2 Gene

Selected SIMAP similar genes for OR8G2 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with OR8G2: view

No data available for Paralogs for OR8G2 Gene

Variants for OR8G2 Gene

Sequence variations from dbSNP and Humsavar for OR8G2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
VAR_058309 -

Structural Variations from Database of Genomic Variants (DGV) for OR8G2 Gene

Variant ID Type Subtype PubMed ID
dgv82n21 CNV Gain 19592680
nsv898435 CNV Gain 21882294
esv2745180 CNV Deletion 23290073
esv2745181 CNV Deletion 23290073
nsv898436 CNV Gain 21882294
nsv442245 CNV CNV 18776908

Relevant External Links for OR8G2 Gene

HapMap Linkage Disequilibrium report
OR8G2

Disorders for OR8G2 Gene

No disorders were found for OR8G2 Gene.

No data available for UniProtKB/Swiss-Prot for OR8G2 Gene

Publications for OR8G2 Gene

  1. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P. … Parmentier M. (Genomics 1997) 2 3 4
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for OR8G2 Gene

Sources for OR8G2 Gene

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