Free for academic non-profit institutions. Other users need a Commercial license

Aliases for OR8G2 Gene

Aliases for OR8G2 Gene

  • Olfactory Receptor Family 8 Subfamily G Member 2 2 3
  • OR8G2P 3 4 5
  • Olfactory Receptor OR11-292 3 4
  • Olfactory Receptor TPCR120 3 4
  • Olfactory Receptor 8G4 3 4
  • OR8G4 3 4
  • Olfactory Receptor, Family 8, Subfamily G, Member 2 Pseudogene 2
  • Olfactory Receptor, Family 8, Subfamily G, Member 2 2
  • Olfactory Receptor, Family 8, Subfamily G, Member 4 3
  • Seven Transmembrane Helix Receptor 3
  • Olfactory Receptor OR11-297 3
  • Olfactory Receptor 8G2 3
  • HSTPCR120 3
  • TPCR120 3
  • ORL206 3
  • ORL486 3

External Ids for OR8G2 Gene

Previous HGNC Symbols for OR8G2 Gene

  • OR8G2P
  • OR8G4

Previous GeneCards Identifiers for OR8G2 Gene

  • GC11P126096
  • GC11M125608
  • GC11P124089
  • GC11P123633
  • GC11P123600
  • GC11P124078
  • GC11P124095
  • GC11P120037
  • GC11P124079

Summaries for OR8G2 Gene

Entrez Gene Summary for OR8G2 Gene

  • Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

GeneCards Summary for OR8G2 Gene

OR8G2 (Olfactory Receptor Family 8 Subfamily G Member 2) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway. GO annotations related to this gene include G-protein coupled receptor activity and olfactory receptor activity.

UniProtKB/Swiss-Prot for OR8G2 Gene

  • Odorant receptor.

Gene Wiki entry for OR8G2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for OR8G2 Gene

Genomics for OR8G2 Gene

Regulatory Elements for OR8G2 Gene

Enhancers for OR8G2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F124521 0.3 FANTOM5 9.5 +296.9 296857 0.3 OR8A1 OR8B8 OR10G7 OR8G2 OR8G1 OR8B12 OR8D1 OR8D2 OR8B10P OR8A3P
GH11F124588 0.4 FANTOM5 7 +364.4 364428 0.4 OR8A1 OR8G1 OR8D1 OR8D2 OR8G2 OR8B12 OR8B8 SPA17 OR8Q1P
GH11F123740 0.9 FANTOM5 ENCODE 6.8 -482.6 -482566 3.8 CREB3L1 MLX ARID4B SIN3A DMAP1 YY1 ZNF143 KLF13 ZNF263 SP3 ZNF202 OR6X1 OR10G7 OR6M1 OR10G4 OR8G2 OR4D5 TMEM225 OR6T1 OR8D4
GH11F124191 0.8 FANTOM5 3 -32.6 -32550 0.3 DDX20 MAFG VWA5A OR8A1 OR6X1 OR10G7 OR8G2 OR8B12 OR4D5 OR10G4 OR6M1 OR8G1
GH11F124008 0.3 FANTOM5 2.5 -216.0 -215965 0.4 OR8D1 OR4D5 OR10G9 OR8D4 OR10G4 OR6M1 OR8G1 OR10S1 OR8D2 OR6X1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around OR8G2 on UCSC Golden Path with GeneCards custom track

Genomic Location for OR8G2 Gene

Chromosome:
11
Start:
124,224,639 bp from pter
End:
124,225,663 bp from pter
Size:
1,025 bases
Orientation:
Plus strand

Genomic View for OR8G2 Gene

Genes around OR8G2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
OR8G2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for OR8G2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for OR8G2 Gene

Proteins for OR8G2 Gene

  • Protein details for OR8G2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IF36-OR8G2_HUMAN
    Recommended name:
    Olfactory receptor 8G2
    Protein Accession:
    Q6IF36
    Secondary Accessions:
    • Q15614
    • Q6IF38

    Protein attributes for OR8G2 Gene

    Size:
    304 amino acids
    Molecular mass:
    33950 Da
    Quaternary structure:
    No Data Available

neXtProt entry for OR8G2 Gene

Post-translational modifications for OR8G2 Gene

Other Protein References for OR8G2 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for OR8G2 Gene

Domains & Families for OR8G2 Gene

Gene Families for OR8G2 Gene

Protein Domains for OR8G2 Gene

Graphical View of Domain Structure for InterPro Entry

Q6IF36

UniProtKB/Swiss-Prot:

OR8G2_HUMAN :
  • Belongs to the G-protein coupled receptor 1 family.
Family:
  • Belongs to the G-protein coupled receptor 1 family.
genes like me logo Genes that share domains with OR8G2: view

Function for OR8G2 Gene

Molecular function for OR8G2 Gene

UniProtKB/Swiss-Prot Function:
Odorant receptor.

Gene Ontology (GO) - Molecular Function for OR8G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004930 G-protein coupled receptor activity IEA --
GO:0004984 olfactory receptor activity IEA --
genes like me logo Genes that share ontologies with OR8G2: view

Phenotypes for OR8G2 Gene

genes like me logo Genes that share phenotypes with OR8G2: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for OR8G2 Gene

Localization for OR8G2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for OR8G2 Gene

Cell membrane; Multi-pass membrane protein.

Gene Ontology (GO) - Cellular Components for OR8G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with OR8G2: view

No data available for Subcellular locations from COMPARTMENTS for OR8G2 Gene

Pathways & Interactions for OR8G2 Gene

genes like me logo Genes that share pathways with OR8G2: view

Pathways by source for OR8G2 Gene

1 BioSystems pathway for OR8G2 Gene
1 KEGG pathway for OR8G2 Gene

Interacting Proteins for OR8G2 Gene

Gene Ontology (GO) - Biological Process for OR8G2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007186 G-protein coupled receptor signaling pathway IEA --
GO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA --
genes like me logo Genes that share ontologies with OR8G2: view

No data available for SIGNOR curated interactions for OR8G2 Gene

Transcripts for OR8G2 Gene

mRNA/cDNA for OR8G2 Gene

(1) REFSEQ mRNAs :
(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for OR8G2 Gene

No ASD Table

Relevant External Links for OR8G2 Gene

GeneLoc Exon Structure for
OR8G2
ECgene alternative splicing isoforms for
OR8G2

Expression for OR8G2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for OR8G2 Gene

mRNA differential expression in normal tissues according to GTEx for OR8G2 Gene

This gene is overexpressed in Testis (x43.9) and Cervix - Endocervix (x9.1).

NURSA nuclear receptor signaling pathways regulating expression of OR8G2 Gene:

OR8G2

SOURCE GeneReport for Unigene cluster for OR8G2 Gene:

Hs.381319
genes like me logo Genes that share expression patterns with OR8G2: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for OR8G2 Gene

Orthologs for OR8G2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for OR8G2 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC100687661 34
  • 86.64 (n)
cow
(Bos Taurus)
Mammalia LOC513062 34
  • 85.48 (n)
mouse
(Mus musculus)
Mammalia Or8g2 55 Olfr229 34 16
  • 83.51 (n)
Or8g20 55 Olfr44
  • chr9:39,484,310-39,485,251
Or8g23 55 Olfr937
  • chr9:39,059,732-39,060,664
Or8g24 55 Olfr938
  • chr9:39,077,799-39,078,743
Or8g2b 55 Olfr971
  • chr9:39,839,436-39,840,356
Or8g30 55 Olfr948
  • chr9:39,318,650-39,319,612
Or8g33 55 Olfr952
  • chr9:39,426,128-39,427,069
Or8g35 55 Olfr955
  • chr9:39,469,783-39,470,724
Or8g36 55 Olfr957
  • chr9:39,510,786-39,511,718
Or8g37 55 Olfr970
  • chr9:39,819,641-39,820,573
Species where no ortholog for OR8G2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for OR8G2 Gene

ENSEMBL:
Gene Tree for OR8G2 (if available)
TreeFam:
Gene Tree for OR8G2 (if available)

Paralogs for OR8G2 Gene

(442) SIMAP similar genes for OR8G2 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with OR8G2: view

No data available for Paralogs for OR8G2 Gene

Variants for OR8G2 Gene

Sequence variations from dbSNP and Humsavar for OR8G2 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs10893172 -- 124,224,709(+) TTCCT(C/G)CGTAG intron-variant, reference, missense
rs111305384 -- 124,224,055(+) ATTTA(A/G)CCGCT intron-variant, upstream-variant-2KB
rs111629383 -- 124,223,297(+) CATTT(A/G)GCTCC intron-variant, upstream-variant-2KB
rs111642092 -- 124,224,489(+) AAATG(A/G)TAATA intron-variant, upstream-variant-2KB
rs112166774 -- 124,225,663(+) TGTTC(A/C)TGAAT intron-variant, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for OR8G2 Gene

Variant ID Type Subtype PubMed ID
dgv57n111 CNV duplication 26073780
dgv82n21 CNV gain 19592680
esv2745180 CNV deletion 23290073
esv2745181 CNV deletion 23290073
esv3627973 CNV gain 21293372
nsv442245 CNV gain 18776908
nsv826110 CNV gain 20364138
nsv975237 CNV duplication 23825009

Relevant External Links for OR8G2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
OR8G2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for OR8G2 Gene

Disorders for OR8G2 Gene

Relevant External Links for OR8G2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
OR8G2

No disorders were found for OR8G2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for OR8G2 Gene

Publications for OR8G2 Gene

  1. Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species. (PMID: 9119360) Vanderhaeghen P. … Parmentier M. (Genomics 1997) 2 3 4 64
  2. The human olfactory receptor gene family. (PMID: 14983052) Malnic B. … Buck L.B. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4 64
  3. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for OR8G2 Gene

Sources for OR8G2 Gene

Content
Loading form....